Abstract:
:The authors examined the relation of negative affect to mortality in the Religious Orders Study, a longitudinal cohort study of older persons, between 1994 and 2002. Participants were 851 Catholic clergy members without dementia at baseline (mean age, 75.4 (standard deviation, 6.9) years; 68% women). They completed standard measures of depressive symptoms, proneness to anxiety and anger, and patterns of anger expression at baseline and then underwent annual clinical evaluations for a mean of 4.7 (standard deviation, 2.7) years. The association of each scale with mortality was examined in proportional hazards models adjusted for age, sex, education, measures of cognitive function, lower limb function, chronic illness, smoking, alcohol, and obesity. During follow-up, 164 persons died. Measures of internally experienced negative affect, such as depressive symptoms and suppressed anger, were related to mortality, but measures of externally directed negative affect, such as the tendencies to be angry with others and to express anger overtly, were not. Persons with a high score (90th percentile) on a summary measure of internally experienced negative affect were nearly twice as likely to die as persons with a low score (10th percentile). The results suggest that negative affect in older persons, especially internally experienced distress, is associated with an increased mortality risk.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Wilson RS,Bienias JL,Mendes de Leon CF,Evans DA,Bennett DAdoi
10.1093/aje/kwg224subject
Has Abstractpub_date
2003-11-01 00:00:00pages
827-35issue
9eissn
0002-9262issn
1476-6256journal_volume
158pub_type
杂志文章abstract::A recent study of two communities in Massachusetts showed that a group of high school sophomores exposed to 107 mg/liter sodium in their municipal drinking water had significantly higher systolic and diastolic blood pressures than a control group exposed to 8 mg/liter. The present study was undertaken to determine if ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a113252
更新日期:1981-12-01 00:00:00
abstract::The purpose of the present analysis was to use longitudinal data collected over 7 years (from 4 surveys) in the Residential Environments (RESIDE) Study (Perth, Australia, 2003-2012) to more carefully examine the relationship of neighborhood walkability and destination accessibility with walking for transportation that...
journal_title:American journal of epidemiology
pub_type: 杂志文章,随机对照试验
doi:10.1093/aje/kwu171
更新日期:2014-09-01 00:00:00
abstract::Male drivers sustained relatively more serious motorcycle collision injuries than did male passengers, female drivers, or female passengers. For male drivers, severity of injury was related to age. The relative frequency of serious head injury was highest for drivers not wearing helmets who were involved in collisions...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a112137
更新日期:1975-07-01 00:00:00
abstract::The relation between use of conjugated estrogens and the risk of uterine cancer was examined among 188 white women with newly diagnosed endometrial cancer and 428 controls hospitalized for nonmalignant conditions requiring surgery at the Boston Hospital for Women-Parkway Division, Boston, Massachusetts, in January 197...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a114414
更新日期:1986-09-01 00:00:00
abstract::Experimentally, high-carbohydrate diets have been shown to elevate triglycerides, but it has not been established whether this rise is permanent or transient. The authors approached this question by studying 719 boys from worldwide populations with marked differences in long-term carbohydrate intake. Fasting serum tri...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a115497
更新日期:1990-02-01 00:00:00
abstract::Iron, potassium, zinc, and other minerals might impact the development of premenstrual syndrome (PMS) through multiple mechanisms, but few studies have evaluated these relations. We conducted a case-control study nested within the prospective Nurses' Health Study II (1991-2001). Participants were free from PMS at base...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kws363
更新日期:2013-05-15 00:00:00
abstract::Many nonrandomized interventions rely upon a pre-post design to evaluate effectiveness. Such designs cannot account for events external to the intervention that may produce the outcome. We describe a method to construct a surveillance registry-based comparison group, which allows for estimating the effectiveness of th...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwy103
更新日期:2018-09-01 00:00:00
abstract::The authors examined the relation between 50 widely used agricultural pesticides and lung cancer incidence in the Agricultural Health Study, a prospective cohort study of 57,284 pesticide applicators and 32,333 spouses of farmer applicators with no prior history of lung cancer. Self-administered questionnaires were co...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwh290
更新日期:2004-11-01 00:00:00
abstract::The authors examined the prevalence of congenital malformations among births in Benton and Franklin counties, in southeastern Washington State, from 1968 through 1980. The Hanford Site is in this area and serves as a major employer. In addition, various agriculturally and chemically related activities are in the area....
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a114800
更新日期:1988-02-01 00:00:00
abstract::The authors assessed the relation between cigarette smoking and nonspecific inflammatory bowel disease in a case-control study of 124 cases of ulcerative colitis, 109 cases of Crohn's disease, and 250 age- and sex-matched control subjects in hospital for acute nongastric or intestinal conditions unrelated to smoking. ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a114550
更新日期:1987-03-01 00:00:00
abstract::The authors characterized human immunodeficiency virus (HIV) and hepatitis C virus (HCV) incidence and prospective changes in self-reported risk behavior over 2 years among 1,158 injection drug users (IDUs) recruited in Chennai, India, in 2005-2006. At baseline, HIV prevalence was 25.3%, and HCV prevalence was 54.5%. ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwq288
更新日期:2010-12-01 00:00:00
abstract::An analysis of the familial aggregation of blood pressure (BP) was conducted to provide estimates of the role of genes and household environment in determining the phenotypic resemblance between biologically related family members. The biological model used for this analysis parameterizes the correlations between fami...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a112830
更新日期:1979-10-01 00:00:00
abstract::A higher serum phosphorus level is associated with cardiovascular disease (CVD) events among community-living populations. Mechanisms are unknown. The ankle-brachial index (ABI) provides information on both atherosclerosis and arterial stiffness. In this cross-sectional study (2000-2002), the authors evaluated the ass...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwq020
更新日期:2010-04-15 00:00:00
abstract::Seventh-Day Adventists in Tromsø showed a coronary risk factor pattern similar to Seventh-Day Adventists in other parts of the world. Compared with non-Seventh-Day Adventists, serum cholesterol was 1.35 mmol/liter (1974) and 0.83 mmol/liter (1979-1980) lower in males and 0.64 mmol/liter (1979-1980) lower in females. B...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a114162
更新日期:1985-11-01 00:00:00
abstract::1,3-Butadiene and styrene are suspected carcinogens and common chemicals used in the synthesis of rubber. To investigate any potential human hazards from exposure to these chemicals, a case-control study of 59 lymphohematopoietic cancers was conducted within a cohort of male workers employed between 1943 and 1982 in e...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/136.7.843
更新日期:1992-10-01 00:00:00
abstract::Vital statistics data on mortality from malignant melanoma from five countries are simultaneously fit by the method of cohort analysis. After the effects of geographic and temporal trends are removed, the proportion of deaths occurring in the younger age groups is found to be higher in females than in males. Relative ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a113726
更新日期:1984-01-01 00:00:00
abstract::Although psychotropic drug use has been associated with increased risk of falls in long-term care settings; this association may be confounded by the high prevalence of dementia and depression and other fall risk factors. This question was addressed in a prospective cohort study of recurrent falls among 282 ambulatory...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a117619
更新日期:1995-07-15 00:00:00
abstract::Exposures to cadmium, lead, and mercury are associated with adverse health effects, including cardiovascular disease, which may be promoted by lipid peroxidation. The authors examined cadmium, lead, and mercury in relation to plasma levels of F(2)-8α isoprostanes (isoprostane), 9-hydroperoxy-10,12-octadecadienoic acid...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwr375
更新日期:2012-04-01 00:00:00
abstract::A national serosurvey was conducted in Mexico from March to October 1986 to identify predictors of dengue transmission and target areas at high risk of severe annual epidemics. A total of 3,408 households in 70 localities with populations less than 50,000 were randomly sampled, and serology was obtained from one subje...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a115829
更新日期:1991-06-01 00:00:00
abstract::Evaluation of adult health risks from exposures that occurred in childhood may require case-control studies in which subjects who are now adults are asked to provide information that might be more accurately provided by their parents. The quality of parental smoking and drinking histories provided by adult offspring w...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a114453
更新日期:1986-11-01 00:00:00
abstract::Exceptionally high incidence rates of thyroid cancer are observed in New Caledonia, particularly in Melanesian women. To investigate further the etiology of thyroid cancer and to clarify the reasons of this elevated incidence, the authors conducted a countrywide population-based case-control study in this multiethnic ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwm204
更新日期:2007-11-15 00:00:00
abstract::The authors examined the relative importance of dietary sodium, potassium, calcium, and magnesium intakes as correlates of blood pressure in a cross-sectional analysis of 987 black and 1,043 white 9- and 10-year-old girls from Richmond, California, Cincinnati, Ohio, and Washington, DC, who were enrolled in the Nationa...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a116975
更新日期:1994-01-15 00:00:00
abstract::The authors abstracted a sample of 7,536 hospital medical records to validate the accuracy of the coding of obstetric information on 1) birth certificates, 2) a statewide computerized hospital discharge abstract data system, and 3) a linked file merging birth certificates and the hospital abstract data for Washington ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a116834
更新日期:1993-07-15 00:00:00
abstract::This study examined the validity of self-reported delivery weight among 3,518 respondents to the 1988 National Maternal and Infant Health Survey. Self-reported delivery weight was ascertained from a mail survey administered during the postpartum period. Measured delivery weight was obtained by abstraction of medical r...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a010103
更新日期:1999-11-01 00:00:00
abstract::Glucose intolerance and diabetes mellitus are associated with physical inactivity, but it is unclear whether preventive interventions should aim at increasing overall energy expenditure or increasing participation in vigorous, fitness-enhancing activities. Studies aimed at separating and quantifying the effects of the...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/152.2.132
更新日期:2000-07-15 00:00:00
abstract::The US Great Recession resulted in an alarming number of home foreclosures that weakened the social and physical environment of thousands of neighborhoods. Few studies have evaluated whether these neighborhood changes were related to changes in individual behaviors. We examined the relationship between changes in neig...
journal_title:American journal of epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1093/aje/kwy075
更新日期:2018-09-01 00:00:00
abstract::Cytomegalovirus (CMV) is a common worldwide perinatal infection. Although usually asymptomatic, it may cause deafness in up to 15% of these infants. A cross-sectional study was performed to determine the age-specific prevalence of CMV seropositivity in Chinese children and to determine if any risk factors for infectio...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a115467
更新日期:1990-01-01 00:00:00
abstract::The aim of this study was to identify individual predisposing risk indicators for falls in a sample of institutionalized frail elderly in southern Germany. The design was a prospective observational study with a 1-year follow-up (October 1998-September 1999). The study population included 472 long-term-care residents ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwg203
更新日期:2003-10-01 00:00:00
abstract::Previous studies have provided conflicting evidence on whether being a family caregiver is associated with increased or decreased risk for all-cause mortality. This study examined whether 3,503 family caregivers enrolled in the national Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study showed dif...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwt225
更新日期:2013-11-15 00:00:00
abstract::An estimated 80% of sexually active young women in the United States use hormonal contraceptives during their reproductive years. Associations between hormonal contraceptive use and mood disturbances remain understudied, despite the hypothesis that estrogen and progesterone play a role in mood problems. In this study,...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwt188
更新日期:2013-11-01 00:00:00