Family caregiving and all-cause mortality: findings from a population-based propensity-matched analysis.

Abstract:

:Previous studies have provided conflicting evidence on whether being a family caregiver is associated with increased or decreased risk for all-cause mortality. This study examined whether 3,503 family caregivers enrolled in the national Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study showed differences in all-cause mortality from 2003 to 2012 compared with a propensity-matched sample of noncaregivers. Caregivers were individually matched with 3,503 noncaregivers by using a propensity score matching procedure based on 15 demographic, health history, and health behavior covariates. During an average 6-year follow-up period, 264 (7.5%) of the caregivers died, which was significantly fewer than the 315 (9.0%) matched noncaregivers who died during the same period. A proportional hazards model indicated that caregivers had an 18% reduced rate of death compared with noncaregivers (hazard ratio = 0.823, 95% confidence interval: 0.699, 0.969). Subgroup analyses by race, sex, caregiving relationship, and caregiving strain failed to identify any subgroups with increased rates of death compared with matched noncaregivers. Public policy and discourse should recognize that providing care to a family member with a chronic illness or disability is not associated with increased risk of death in most cases, but may instead be associated with modest survival benefits for the caregivers.

journal_name

Am J Epidemiol

authors

Roth DL,Haley WE,Hovater M,Perkins M,Wadley VG,Judd S

doi

10.1093/aje/kwt225

subject

Has Abstract

pub_date

2013-11-15 00:00:00

pages

1571-8

issue

10

eissn

0002-9262

issn

1476-6256

pii

kwt225

journal_volume

178

pub_type

杂志文章
  • The use of logistic regression for modelling risk factors: with application to non-melanoma skin cancer.

    abstract::Logistic regression was used to estimate the "relative" risk of basal and squamous skin cancer for such factors as cumulative lifetime solar exposure, age, complexion, and tannability. In previous reports, a subject's exposure was estimated indirectly, by latitude, or by the number of sun days in a subject's habitat. ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a112638

    authors: Vitaliano PP

    更新日期:1978-11-01 00:00:00

  • Adverse birth outcomes associated with open dumpsites in Alaska Native Villages.

    abstract::This retrospective cohort study evaluated adverse birth outcomes in infants whose birth records indicated maternal residence in villages containing dumpsites potentially hazardous to health and environment. Birth records from 1997 to 2001 identified 10,073 eligible infants born to mothers in 197 Alaska Native villages...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwj241

    authors: Gilbreath S,Kass PH

    更新日期:2006-09-15 00:00:00

  • Hepatitis A in Peru. The role of children.

    abstract::A serologic survey in 1983-1984 evaluated the presence of hepatitis A antibody (anti-HAV) and hepatitis A immunoglobulin M antibody (anti-HAV IgM) in 3,251 adults and 811 children in the jungle and coastal areas of Peru. All subjects were asymptomatic. Adults had a 98% positive anti-HAV rate except for naval cadets, w...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a114354

    authors: Kilpatrick ME,Escamilla J

    更新日期:1986-07-01 00:00:00

  • Validation of a small set of ancestral informative markers for control of population admixture in African Americans.

    abstract::Confounding due to population stratification is a potential source of concern in population-based genetic association studies, particularly in recently admixed populations such as African Americans. Several methods have been developed to control for population stratification in the context of genome-wide association s...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1093/aje/kwq401

    authors: Ruiz-Narváez EA,Rosenberg L,Wise LA,Reich D,Palmer JR

    更新日期:2011-03-01 00:00:00

  • High sodium in drinking water and its effect on blood pressure.

    abstract::A recent study of two communities in Massachusetts showed that a group of high school sophomores exposed to 107 mg/liter sodium in their municipal drinking water had significantly higher systolic and diastolic blood pressures than a control group exposed to 8 mg/liter. The present study was undertaken to determine if ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113252

    authors: Hallenbeck WH,Brenniman GR,Anderson RJ

    更新日期:1981-12-01 00:00:00

  • Boy/girl differences in risk for reading disability: potential clues?

    abstract::The authors conducted a case-control study to determine whether risk factors for reading disability (RD) differentially affect boys and girls. The study population included all children born between 1976 and 1982 in Olmsted County, Minnesota (n = 5,701). A total of 303 RD cases were identified by using intelligence qu...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/154.9.787

    authors: St Sauver JL,Katusic SK,Barbaresi WJ,Colligan RC,Jacobsen SJ

    更新日期:2001-11-01 00:00:00

  • Basal-cell carcinoma incidence and associated risk factors in U.S. women and men.

    abstract::There is a paucity of data on basal-cell carcinoma (BCC) in the United States, since most national registries do not collect information on BCC. We evaluated BCC incidence trends and associated risk factors for BCC in 140,171 participants from a U.S. female cohort, the Nurses' Health Study (1986-2006), and a U.S. male...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwt073

    authors: Wu S,Han J,Li WQ,Li T,Qureshi AA

    更新日期:2013-09-15 00:00:00

  • Magnetic field exposure from electric appliances and childhood cancer.

    abstract::The effect on childhood cancer of prolonged exposure to 60-H magnetic fields from electric appliances was examined using interview data from a recently completed case-control study. Exposures of children aged 0-14 years whose incident cancers were diagnosed between 1976 and 1983 and who resided in the Denver, Colorado...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a115566

    authors: Savitz DA,John EM,Kleckner RC

    更新日期:1990-05-01 00:00:00

  • Correction for biases in a population-based study of family history and coronary heart disease. The Newcastle Family History Study I.

    abstract::In this paper, the authors report on the design of a population-based case-control study of family history as a risk factor for coronary heart disease (CHD). They studied the characteristics of subjects who completed a detailed family history questionnaire in 1992-1994 as well as the accuracy of recall of family histo...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a009410

    authors: Silberberg JS,Wlodarczyk J,Fryer J,Ray CD,Hensley MJ

    更新日期:1998-06-15 00:00:00

  • All-cause, cardiovascular, and cancer mortality rates in postmenopausal white, black, Hispanic, and Asian women with and without diabetes in the United States: the Women's Health Initiative, 1993-2009.

    abstract::Using data from the Women's Health Initiative (1993-2009; n = 158,833 participants, of whom 84.1% were white, 9.2% were black, 4.1% were Hispanic, and 2.6% were Asian), we compared all-cause, cardiovascular, and cancer mortality rates in white, black, Hispanic, and Asian postmenopausal women with and without diabetes....

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwt177

    authors: Ma Y,Hébert JR,Balasubramanian R,Wedick NM,Howard BV,Rosal MC,Liu S,Bird CE,Olendzki BC,Ockene JK,Wactawski-Wende J,Phillips LS,Lamonte MJ,Schneider KL,Garcia L,Ockene IS,Merriam PA,Sepavich DM,Mackey RH,Johnson KC

    更新日期:2013-11-15 00:00:00

  • Stroke incidence among white, black, and Hispanic residents of an urban community: the Northern Manhattan Stroke Study.

    abstract::Stroke mortality is reported to be greater in blacks than in whites, but stroke incidence data for blacks and Hispanics are sparse. The aim of this study was to determine and compare stroke incidence rates among whites, blacks, and Hispanics living in the same urban community. A population-based incidence study was co...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a009445

    authors: Sacco RL,Boden-Albala B,Gan R,Chen X,Kargman DE,Shea S,Paik MC,Hauser WA

    更新日期:1998-02-01 00:00:00

  • Alcohol consumption at the time of conception and spontaneous abortion.

    abstract::The authors studied the association between female and male alcohol intakes at the time of conception and the risk of spontaneous abortion, including early pregnancy loss detected by urinary human chorionic gonadotropin. After a nationwide mailing to about 50,000 members of four trade unions in Denmark in 1992-1994, 4...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwh259

    authors: Henriksen TB,Hjollund NH,Jensen TK,Bonde JP,Andersson AM,Kolstad H,Ernst E,Giwercman A,Skakkebaek NE,Olsen J

    更新日期:2004-10-01 00:00:00

  • The descriptive epidemiology of pneumococcal meningitis in New York City.

    abstract::A total of 348 cases of meningitis caused by Streptococcus pneumoniae were reported to and investigated by the New York City Department of Health during the six years 1973-1978. The descriptive epidemiology and completeness of reporting of this disease entity are presented. The total crude incidence was estimated at 1...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113566

    authors: Henneberger PK,Galaid EI,Marr JS

    更新日期:1983-04-01 00:00:00

  • Factors associated with earthquake deaths in the great Hanshin-Awaji earthquake, 1995.

    abstract::The authors conducted descriptive and case-control studies to find factors associated with earthquake deaths due to the Great Hanshin-Awaji earthquake on January 17, 1995, in Nishinomiya, Japan. In the case-control study, cases included all 1,104 deaths. Controls were randomly selected from survivors. Earthquake morta...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/153.2.153

    authors: Osaki Y,Minowa M

    更新日期:2001-01-15 00:00:00

  • "First-wave" bias when conducting active safety monitoring of newly marketed medications with outcome-indexed self-controlled designs.

    abstract::Large health care databases are used extensively for pharmacoepidemiologic studies. Unique methodological issues arise when applying self-controlled designs (i.e., using within-person comparisons) for active surveillance of newly marketed drugs. We use 3 examples to illustrate bias related to population-level exposure...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwu162

    authors: Wang SV,Schneeweiss S,Maclure M,Gagne JJ

    更新日期:2014-09-15 00:00:00

  • The performance of three approximate confidence limit methods for the odds ratio.

    abstract::The performance of three approximate confidence limit methods for the odds ratio, R, is studied at the 95% level in the unconditional sample space. There are: the method proposed by Cornfield (Proceedings of the 3rd Berkeley Symposium 1956;4:135-48), the logit method with 1/2 corrections first considered by Woolf (Ann...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113323

    authors: Gart JJ,Thomas DG

    更新日期:1982-03-01 00:00:00

  • Occupational exposures and male infertility.

    abstract::The purpose of this study was to determine the association between male occupational exposures and infertility. A retrospective case-control study was performed using data collected between 1991 and 1997 at nine US clinical sites as part of a previously conducted large multicenter trial. Cases were defined as infertil...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章,多中心研究

    doi:10.1093/aje/kwi269

    authors: Gracia CR,Sammel MD,Coutifaris C,Guzick DS,Barnhart KT

    更新日期:2005-10-15 00:00:00

  • Persistent mood symptoms in a multiethnic community cohort of pre- and perimenopausal women.

    abstract::To further our understanding of the relation between mood and menopause, the authors examined 1) the association between persistent mood symptoms and menopausal status and 2) factors that increase a woman's vulnerability to an overall dysphoric mood during the early perimenopausal period. The sample consisted of an et...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwg155

    authors: Bromberger JT,Assmann SF,Avis NE,Schocken M,Kravitz HM,Cordal A

    更新日期:2003-08-15 00:00:00

  • Evidence from nonrandomized studies: a case study on the estimation of causal effects.

    abstract::Although randomized controlled trials are regarded as the gold standard for comparison of treatments, evidence from observational studies is still relevant. To cope with the problem of possible confounding in these studies, investigators need methods for analyzing their results which adjust for confounders and lead to...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwn010

    authors: Schmoor C,Caputo A,Schumacher M

    更新日期:2008-05-01 00:00:00

  • Racial variations in vision.

    abstract::This study determined the distributions of uncorrected visual acuity and of refractive error in representative groups of Australian Aborigines and Australians of European origin aged 20-30 years. The methodology used in this study and its verification are described in detail. As a group, the Aborigines have significan...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a113067

    authors: Taylor HR

    更新日期:1981-01-01 00:00:00

  • Recent exposure to particulate matter and C-reactive protein concentration in the multi-ethnic study of atherosclerosis.

    abstract::Ambient levels of particulate matter have been linked to cardiovascular disease. The mechanisms mediating these associations are poorly understood. One candidate mechanism is inflammation. Using data from the Multi-Ethnic Study of Atherosclerosis (2000-2002), the authors investigated the relation between exposure to p...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwj186

    authors: Diez Roux AV,Auchincloss AH,Astor B,Barr RG,Cushman M,Dvonch T,Jacobs DR Jr,Kaufman J,Lin X,Samson P

    更新日期:2006-09-01 00:00:00

  • Dietary cation intake and blood pressure in black girls and white girls.

    abstract::The authors examined the relative importance of dietary sodium, potassium, calcium, and magnesium intakes as correlates of blood pressure in a cross-sectional analysis of 987 black and 1,043 white 9- and 10-year-old girls from Richmond, California, Cincinnati, Ohio, and Washington, DC, who were enrolled in the Nationa...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a116975

    authors: Simon JA,Obarzanek E,Daniels SR,Frederick MM

    更新日期:1994-01-15 00:00:00

  • Repeated hospitalizations and self-rated health among the elderly: a multivariate failure time analysis.

    abstract::The purpose of this study was to determine to what extent a single measure, self-rated health (SRH), independently predicts long-term hospitalizations due to all causes and to cardiovascular diseases by using both the standard Cox proportional hazards model and a more robust events model. The study cohort consisted of...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/153.3.232

    authors: Kennedy BS,Kasl SV,Vaccarino V

    更新日期:2001-02-01 00:00:00

  • Arsenic exposure, smoking, and lung cancer in smelter workers--a case-control study.

    abstract::A cohort of 3,916 Swedish copper smelter workers employed for at least 3 months between 1928 and 1967 was followed up through 1981. Arsenic exposure was estimated for different time periods at each workplace within the smelter. Detailed job records were linked to the exposure matrix, thus forming individual cumulative...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a116128

    authors: Järup L,Pershagen G

    更新日期:1991-09-15 00:00:00

  • Body fat distribution and osteoarthritis.

    abstract::The association of body fat distribution with single and combined site osteoarthritis was investigated using data from the US Health Examination Survey I, 1960-1962 (HES I) and the first National Health and Nutrition Examination Survey I, 1971-1975 (NHANES I). The study included 1,636 adults aged 35-79 years from HES ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a115711

    authors: Davis MA,Neuhaus JM,Ettinger WH,Mueller WH

    更新日期:1990-10-01 00:00:00

  • Strategies for pandemic and seasonal influenza vaccination of schoolchildren in the United States.

    abstract::Vaccinating school-aged children against influenza can reduce age-specific and population-level illness attack rates. Using a stochastic simulation model of influenza transmission, the authors assessed strategies for vaccinating children in the United States, varying the vaccine type, coverage level, and reproductive ...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwp237

    authors: Basta NE,Chao DL,Halloran ME,Matrajt L,Longini IM Jr

    更新日期:2009-09-15 00:00:00

  • Risk factors for secondary transmission in households after a common-source outbreak of Norwalk gastroenteritis.

    abstract::In November 1984, a foodborne outbreak of Norwalk gastroenteritis occurred in a K-12 public school in northern Vermont. The outbreak offered an opportunity to systematically study in detail secondary transmission rates in households. Eating salad at Tuesday's school-sponsored Thanksgiving Banquet was associated with i...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a114756

    authors: Heun EM,Vogt RL,Hudson PJ,Parren S,Gary GW

    更新日期:1987-12-01 00:00:00

  • Retinal arteriolar diameters and elevated blood pressure: the Atherosclerosis Risk in Communities Study.

    abstract::Narrowing and other changes in retinal arterioles may reflect damage due to hypertension, which may predict stroke and other cardiovascular diseases independently of blood pressure level. Newly developed quantitative methods of assessing retinal narrowing are used to determine whether this sign is related only to curr...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.aje.a009997

    authors: Sharrett AR,Hubbard LD,Cooper LS,Sorlie PD,Brothers RJ,Nieto FJ,Pinsky JL,Klein R

    更新日期:1999-08-01 00:00:00

  • Racial and Ethnic Disparities in the Incidence of Esophageal Cancer in the United States, 1992-2013.

    abstract::Racial and ethnic disparities in the incidence of esophageal cancer have not been thoroughly characterized with quantitative health-disparity measures. Using data from 1992-2013 from 13 US cancer registries in the Surveillance, Epidemiology, and End Results database, we assessed such disparities according to histologi...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwx221

    authors: Xie SH,Rabbani S,Petrick JL,Cook MB,Lagergren J

    更新日期:2017-12-15 00:00:00

  • Genetic variation in the progesterone receptor gene and ovarian cancer risk.

    abstract::Evidence suggests a role for progesterone in ovarian cancer development. Progesterone exerts its effect on target cells by interacting with its receptor. Thus, genetic variations that may cause alterations in the biologic functions of the progesterone receptor can potentially contribute to individual susceptibility to...

    journal_title:American journal of epidemiology

    pub_type: 杂志文章

    doi:10.1093/aje/kwi064

    authors: Terry KL,De Vivo I,Titus-Ernstoff L,Sluss PM,Cramer DW

    更新日期:2005-03-01 00:00:00