Osteonecrosis in a chemically induced rat model of human hemolytic disorders associated with thrombosis--a new model for avascular necrosis of bone.

abstract：:There is considerable interest in determining whether hypergravity can be used as a countermeasure for microgravity-induced bone loss. This study was conducted on 20 immature male rats in order to investigate possible elastic adaptations of cortical bone in rapidly growing rats exposed to chronic hypergravity. Ten rat...

journal_title：Calcified tissue international

authors： Kohles SS,Bowers JR,Vailas AC,Vanderby R Jr

更新日期：1996-09-01 00:00:00

abstract：:Thyroxine (T4), triiodothyronine (T3), and alkaline phosphatase (AP) were assayed monthly in white-tailed deer plasma obtained from the antler (A), jugular (J), and the saphenous (S) veins during the period of antler growth and the period of mineralization. The concentrations of T3, T4, and AP in the J and S were not ...

journal_title：Calcified tissue international

authors： Bubenik GA,Sempere AJ,Hamr J

更新日期：1987-07-01 00:00:00

abstract：:We carried out a clinical trial of 1 alpha-hydroxycholecalciferol [1 alpha(OH)D3] at a dose of 1.0 microgram a day on 7 patients with psoriasis vulgaris. These patients had been treated by topical applications of corticosteroids before this study without improvement, and during the clinical trial, treatment of topical...

journal_title：Calcified tissue international

authors： Takamoto S,Onishi T,Morimoto S,Imanaka S,Yukawa S,Kozuka T,Kitano Y,Seino Y,Kumahara Y

更新日期：1986-12-01 00:00:00

abstract：:There are few longitudinal data on change in bone structure and muscle mass, strength and function in later life. We report these, and consider bone-muscle interrelationships in older men and women. We studied 188 men and 166 women from the Hertfordshire Cohort Study, who underwent peripheral quantitative computed tom...

journal_title：Calcified tissue international

authors： Patel A,Edwards MH,Jameson KA,Ward KA,Fuggle N,Cooper C,Dennison EM

更新日期：2018-11-01 00:00:00

abstract：:The evidence now strongly supports a central role for oestrogen in the maintenance of the normal female skeleton. Loss of endogenous oestrogen leads to a period of accelerated bone loss which can be prevented with appropriate oestrogen replacement. The route of administration is not important provided adequate dosages...

journal_title：Calcified tissue international

authors： Hillard TC,Stevenson JC

更新日期：1991-01-01 00:00:00

abstract：:Pyrolyzed scales, fin spines, and bone from the ray-finned bony fish Polypterus (Actinopterygii) showed two mineral phases on X-ray diffraction: hydroxyapatite (HA), Ca5(PO4)3OH, and whitlockite, Ca3(PO4)2. The ratio of HA/whitlockite varied with the structure (scale, spine, bone) within each individual fish. The rela...

journal_title：Calcified tissue international

authors： Meinke DK,Skinner HC,Thomson KS

更新日期：1979-08-24 00:00:00

abstract：:In the rat, prolonged administration of the luteinizing, hormone-releasing hormone agonist buserelin (25 micrograms/kg body wt/day s.c.) lowers blood estradiol, raises bone resorption, and induces osteopenia. The present study was undertaken to determine whether withdrawal of buserelin normalizes blood estradiol, slow...

journal_title：Calcified tissue international

authors： Goulding A,Gold E

更新日期：1990-01-01 00:00:00

abstract：:The aim of this study was to investigate the relation between birth weight and calcaneal bone stiffness in a large sample of Belgian, healthy, preadolescent children. Participants were 827 children (3.6-11.2 years, 51.6 % boys) from the Belgian cohort of the IDEFICS study. Birth weight was obtained using a parental qu...

journal_title：Calcified tissue international

authors： Van den Bussche K,Michels N,Gracia-Marco L,Herrmann D,Eiben G,De Henauw S,Sioen I

更新日期：2012-10-01 00:00:00

abstract：:Connective tissue diseases, including osteogenesis imperfecta (OI) and Ehlers-Danlos syndrome (EDS), exhibit a high degree of clinical and genetic heterogeneity. We report two sisters with blue sclerae, joint hypermobility and hearing loss. Whole-exome sequencing identified two compound heterozygous ZNF469 loss-of-fun...

journal_title：Calcified tissue international

authors： Rolvien T,Kornak U,Linke SJ,Amling M,Oheim R

更新日期：2020-09-01 00:00:00

abstract：:Test implant plates surgically retrieved from distal femurs of dogs were studied by Raman spectroscopy in order to characterize the bone-implant interface. The implant surface consisted of phosphate mineral, plasma sprayed on a titanium substrate. On the basis of its spectroscopic signature, the phosphate mineral of b...

journal_title：Calcified tissue international

authors： Walters MA,Blumenthal NC,Leung Y,Wang Y,Ricci JL,Spivak JM

更新日期：1991-05-01 00:00:00

abstract：:The phorbol ester 12-O-tetradecanoyl-13-acetate (TPA) blocked the growth of, and induced the appearance of processes in the human osteosarcoma cell line U-2 OS. The phorbol ester decreased the intracellular level of alkaline phosphatase (APase) activity (as measured per mg cell protein) and caused a marked increase in...

journal_title：Calcified tissue international

authors： Ringbom-Anderson T,Akerman KE

更新日期：1992-06-01 00:00:00

abstract：:The purpose of the present work was to investigate the appearance of ossification centers in human femur by Dual-energy X-ray Absorptiometry (DXA), comparing densitometric data with morphogenetic events. Posteroanterior scans were performed on 31 dried femora (from 11.5 weeks of conceptual age to 1 year of postnatal l...

journal_title：Calcified tissue international

authors： Panattoni GL,D'Amelio P,Di Stefano M,Isaia GC

更新日期：2000-04-01 00:00:00

abstract：:Age-related loss of skeletal muscle is associated with increased risk of functional limitation and cardiovascular (CV) mortality. In the elderly abdominal aortic calcification (AAC) can increase CV risk by altering aortic properties which may raise blood pressure and increase cardiac workload. This study investigated ...

journal_title：Calcified tissue international

authors： Rodríguez AJ,Scott D,Khan B,Khan N,Hodge A,English DR,Giles GG,Ebeling PR

更新日期：2016-10-01 00:00:00

abstract：:Duffy antigen receptor for chemokines (DARC) binds to a number of pro-inflammatory chemokines, and since chemokines are known to regulate trafficking of osteoclast (OC) precursors, we predicted that DARC would regulate OC recruitment to sites of inflammation by modulating chemokine activity. To test this hypothesis, w...

journal_title：Calcified tissue international

authors： Alemi F,Elgendy M,Edderkaoui B

更新日期：2016-11-01 00:00:00

abstract：:Raman spectroscopy has been used to demonstrate, for the first time, that calcium mineralization in the core of the major lateral teeth of the chiton Acanthopleura echinata takes place as an ordered process, with crystalline carbonated apatite being the first mineral deposited. Deposition begins at the top of the toot...

journal_title：Calcified tissue international

authors： Lee AP,Brooker LR,Macey DJ,van Bronswijk W,Webb J

更新日期：2000-11-01 00:00:00

abstract：:The acute-phase response (APR) is frequently observed in patients treated with intravenous (iv) zoledronate (ZOL). We investigated whether a short course of rosuvastatin (ROSU) could attenuate the ZOL--induced APR through blocking the mevalonate pathway at a proximal level. Twenty-eight osteoporotic postmenopausal wom...

journal_title：Calcified tissue international

authors： Makras P,Anastasilakis AD,Polyzos SA,Bisbinas I,Sakellariou GT,Papapoulos SE

更新日期：2011-05-01 00:00:00

abstract：:A whole-body counter was used to measure the retention and distribution of radioactivity along the longitudinal axis of the body during 10 days after the intravenous injection of 50 microCi of 47Ca. These data and the simultaneous measurements of the serum specific activity allowed us to calculate, by the Bauer-Carlss...

journal_title：Calcified tissue international

authors： Bergmann P,Paternot T,Schoutens A

更新日期：1983-01-01 00:00:00

abstract：:The CYP3A7 enzyme metabolizes some steroid hormones, including dehydroepiandrosterone sulfate (DHEAS). The age-related decline of serum DHEAS levels is believed to contribute to osteoporosis. Previously, the CYP3A7*1C polymorphism has been shown to cause a persistent high CYP3A7 enzyme activity, resulting in lower lev...

journal_title：Calcified tissue international

authors： Bácsi K,Kósa JP,Borgulya G,Balla B,Lazáry A,Nagy Z,Horváth C,Speer G,Lakatos P

更新日期：2007-03-01 00:00:00

abstract：:Aging bone shows a progressive decline in mass and strength. Previous studies have suggested that bone marrow stem cells are reduced with aging and that this could be responsible, in part, for age-associated bone deficits. We measured the number of osteoprogenitor cells present in the bone marrow from adult and aged r...

journal_title：Calcified tissue international

authors： Quarto R,Thomas D,Liang CT

更新日期：1995-02-01 00:00:00

abstract：:Noncarious cervical lesions have a multifactorial etiology. Mechanical stress has been identified as one of the factors, but little evidence exists for its cause-effect relationship. This study was conducted at three different pH levels to observe the surface loss on dentin beams under tension and compression. Bovine ...

journal_title：Calcified tissue international

authors： Mishra P,Palamara JE,Tyas MJ,Burrow MF

更新日期：2006-12-01 00:00:00

abstract：:Osteoblasts in vitro differentiate from a proliferating to a mineralizing phenotype upon transfer to a medium rich in beta-glycerophosphate and ascorbic acid. The nutritional requirements of the cells at different stages of this differentiation process are not known. In other cell types, nutritional supplementation du...

journal_title：Calcified tissue international

authors： Brown PM,Hutchison JD,Crockett JC

更新日期：2011-12-01 00:00:00

abstract：:Currently used diagnostic measures for sarcopenia are based on the evaluation of appendicular skeletal muscle mass (ASMM) divided by height-squared (ASMMI). This study aimed to investigate the associations between different operational definitions of appendicular muscle mass and BMD at different skeletal sites in agin...

journal_title：Calcified tissue international

authors： Gonnelli S,Caffarelli C,Cappelli S,Rossi S,Giordano N,Nuti R

更新日期：2014-10-01 00:00:00

abstract：:The values of in vivo T1 relaxation time (T1) of phosphorus atoms of wrist bone have been measured by phosphorus-31 magnetic resonance spectroscopy (MRS) in 65 menopausal women separated into three groups: (1) age-matched women without any paraclinical or clinical osteoporosis; (2) patients with paraclinical osteoporo...

journal_title：Calcified tissue international

authors： Confort-Gouny S,Mattéi JP,Vion-Dury J,Roux H,Bisset JP,Cozzone PJ

更新日期：1995-06-01 00:00:00

abstract：:Several studies have demonstrated that bone has the power of regeneration and repair. BMPs (bone morphogenetic proteins) are involved in the determination of osteoblast phenotype and bone turnover, therefore genes coding for these proteins, like BMP-4, could be considered potential candidate genes for osteoporosis. We...

journal_title：Calcified tissue international

authors： Semprini S,Mango R,Brancati F,Dallapiccola B,Becherini L,Novelli G,De Lorenzo A,Brandi ML,Gennari L

更新日期：2000-07-01 00:00:00

abstract：:The main congenital conditions of hypophosphatemia expressed in adulthood include several forms of hereditary hypophosphatemic rickets and a congenital disorder of vitamin D metabolism characterized by osteomalacia and hypophosphatemia in adult patients. Hypophosphatemia in adults is defined as serum phosphate concent...

journal_title：Calcified tissue international

authors： Marcucci G,Brandi ML

更新日期：2021-01-01 00:00:00

abstract：:Genome-wide association studies (GWAS) have demonstrated that genetic variation at the MADS box transcription enhancer factor 2, polypeptide C (MEF2C) locus is robustly associated with bone mineral density, primarily at the femoral neck. MEF2C is a transcription factor known to operate via the Wnt signaling pathway. O...

journal_title：Calcified tissue international

authors： Johnson ME,Deliard S,Zhu F,Xia Q,Wells AD,Hankenson KD,Grant SF

更新日期：2014-04-01 00:00:00

abstract：:We conducted a case-control study on fracture risk associated with the use of orally administered prednisolone/prednisone, budesonide, methylprednisolone, and hydrocortisone to assess if the various preparations were associated with different fracture patterns. Cases were all subjects with any fracture sustained durin...

journal_title：Calcified tissue international

authors： Vestergaard P,Rejnmark L,Mosekilde L

更新日期：2008-04-01 00:00:00

abstract：:Measurement of areal bone mineral density (aBMD) in intravertebral subregions may increase the diagnostic sensitivity of dual-energy X-ray absorptiometry (DXA)-derived parameters for vertebral fragility. This study investigated whether DXA-derived bone parameters in vertebral subregions were better predictors of verte...

journal_title：Calcified tissue international

authors： Briggs AM,Perilli E,Codrington J,Reynolds KJ,Parkinson IH,Wark JD

更新日期：2014-08-01 00:00:00

abstract：:Humanin (HN), a mitochondrial derived peptide, plays cyto-protective role under various stress. In this study, we aimed to investigate the effects of HNGF6A, an analogue of HN, on osteoblast apoptosis and differentiation and the underlying mechanisms. Cell proliferation of murine osteoblastic cell line MC3TC-E1 was ex...

journal_title：Calcified tissue international

authors： Zhu X,Zhao Z,Zeng C,Chen B,Huang H,Chen Y,Zhou Q,Yang L,Lv J,Zhang J,Pan D,Shen J,Duque G,Cai D

更新日期：2020-05-01 00:00:00

abstract：:We have used in situ hybridization to examine expression of collagen type I, II, and X mRNA and osteonectin mRNA in the chick epiphysis. Tissue samples from the proximal tibial growth cartilage were fixed in modified Carnoy's solution, dehydrated in ethanol, and embedded in paraffin. Longitudinal and transverse sectio...

journal_title：Calcified tissue international

authors： Oshima O,Leboy PS,McDonald SA,Tuan RS,Shapiro IM

更新日期：1989-09-01 00:00:00