A randomised double-blind evaluation of adenosine as adjunct to sufentanil in spinal labour analgesia.

Abstract:

BACKGROUND:Intrathecal injection of sufentanil offers labour pain relief of short duration. This double-blind randomised study evaluates if the combination of adenosine to sufentanil could give relevant prolongation (40%) of the duration of sufentanil spinal analgesia. METHODS:Twenty-five healthy parturients requesting labour analgesia were included. Patients received 10 micro g of sufentanil + 500 micro g of adenosine or 10 micro g of sufentanil intrathecally. Pain intensity and duration of pain relief were assessed. RESULTS:Pain relief was equal between groups. Duration of analgesia was not increased by adenosine + sufentanil, 99 +/- 54 min, vs. sufentanil, 89 +/- 56 min. CONCLUSION:Adding 500 micro g of adenosine to 10 micro g of sufentanil could not provide any prolongation of labour pain relief.

authors

Rane K,Sollevi A,Segerdahl M

doi

10.1034/j.1399-6576.2003.00110.x

subject

Has Abstract

pub_date

2003-05-01 00:00:00

pages

601-3

issue

5

eissn

0001-5172

issn

1399-6576

pii

110

journal_volume

47

pub_type

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