Abstract:
:The aim of the study was to investigate the association of physician communication behaviours as perceived by the patient with patient reported satisfaction, distress, cancer-related self-efficacy, and perceived control over the disease in cancer patients. Questionnaires measuring distress, self-efficacy, and perceived control were completed prior to and after the consultation by 454 patients attending an oncology outpatient clinic. After the consultation, the patients also rated the physicians' communicative behaviours by completing a patient-physician relationship inventory (PPRI), and the physicians were asked to estimate patient satisfaction. The overall results showed that higher PPRI scores of physician attentiveness and empathy were associated with greater patient satisfaction, increased self-efficacy, and reduced emotional distress following the consultation. In contrast, lower PPRI scores were associated with reduced ability of the physician to estimate patient satisfaction. The results confirm and expand previous findings, suggesting that communication is a core clinical skill in oncology.
journal_name
Br J Cancerjournal_title
British journal of cancerauthors
Zachariae R,Pedersen CG,Jensen AB,Ehrnrooth E,Rossen PB,von der Maase Hdoi
10.1038/sj.bjc.6600798subject
Has Abstractpub_date
2003-03-10 00:00:00pages
658-65issue
5eissn
0007-0920issn
1532-1827pii
6600798journal_volume
88pub_type
杂志文章abstract::An extensive analysis of the reliability of positron emission tomography (PET) after induction treatment in patients with Hodgkin's disease (HD) or aggressive non-Hodgkin's lymphoma (NHL). In all, 75 untreated patients with HD (n=41) or aggressive NHL (n=34) were studied with both PET and CT scans following standard c...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/sj.bjc.6602040
更新日期:2004-08-31 00:00:00
abstract::In this study we sought factors that determine the survival of human colonic epithelial cells. Normal colonic epithelial cells are dependent on cell-cell contacts and survival factors for the inhibition of apoptosis whereas, during colorectal tumorigenesis, cells develop mechanisms to evade these controls. The ability...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/bjc.1997.167
更新日期:1997-01-01 00:00:00
abstract::This corrects the article DOI: 10.1038/bjc.2017.85. ...
journal_title:British journal of cancer
pub_type: 杂志文章,已发布勘误
doi:10.1038/bjc.2018.3
更新日期:2018-03-20 00:00:00
abstract::Up to 60% of gastro-oesophageal junction (GEJ) adenocarcinomas show nuclear beta-catenin expression, pointing to activated T-cell factor (TCF)/beta-catenin-driven gene transcription. We demonstrate in five human GEJ adenocarcinoma cell lines that nuclear beta-catenin expression indeed correlates with enhanced TCF-medi...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/sj.bjc.6601589
更新日期:2004-02-23 00:00:00
abstract::It has been suggested that World War II influenced breast cancer risk among Norwegian women by affecting adolescent growth. Diet changed substantially during the war, and the reduction in energy intake was assumed to be larger in non-food-producing than in food-producing municipalities. In the present study, we have l...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/sj.bjc.6600084
更新日期:2002-02-01 00:00:00
abstract::Previous studies have demonstrated that BR-931, a hepatic peroxisome proliferator, can induce liver tumours in mice and rats. Since alterations in gene expression may play a critical role in multistage hepatocarcinogenesis, the present studies examined the expression of the c-myc, c-H-ras, epidermal growth factor (EGF...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/bjc.1991.406
更新日期:1991-11-01 00:00:00
abstract::The incidence of Kaposi's sarcoma (KS) in 1976-90 was assessed in Italy, taking advantage of a network of nine population-based cancer registries covering, at its maximum, approximately 5.6 million subjects. The first examined period (1976-84) substantially reflects the epidemiology of KS prior to the AIDS epidemic in...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/bjc.1994.60
更新日期:1994-02-01 00:00:00
abstract::Piwi proteins and their interaction with piRNAs have rapidly emerged as important contributors to gene regulation, indicating their crucial function in germline and stem cell development. However, data on the Hiwi 1 (Hiwi) gene, one of the four human Piwi homologues, are still scarce. Therefore, we investigated the Hi...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/sj.bjc.6604653
更新日期:2008-10-07 00:00:00
abstract::Despite encouraging results from recent studies, there is still no consensus to undertake mass screening using the Haemoccult test in the general population. The success of mass screening for colorectal cancer depends among other things on Haemoccult test properties. In on-going screening programmes, the Haemoccult te...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/bjc.1995.459
更新日期:1995-10-01 00:00:00
abstract::Pulmonary metastasectomy is widely and increasingly practiced in the belief that this intervention can cure patients with colorectal cancer, and that without it few survive 5 years. No good evidence exists supporting such convictions, indeed recent trial results challenge them. What evidence underpins this acceptance ...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/s41416-020-0927-2
更新日期:2020-08-01 00:00:00
abstract::Caffeine has for many years been known to be involved in the sensitization of DNA to damage. One potential mechanism recently put forward is an override of the G2/M block induced by irradiation, which would leave the cells less time for DNA repair prior to mitosis. However, different cell types display a variety of re...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1054/bjoc.2000.1259
更新日期:2000-08-01 00:00:00
abstract::Patients with advanced malignant disease show an apparent lesser degree of lymphocyte sensitization to cancer antigen when tested under standard conditions than do early cases. In the serum of cancer patients there is a lymphocyte response depressing factor whose titre rises as the neoplasm becomes more extensive. The...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/bjc.1972.23
更新日期:1972-06-01 00:00:00
abstract:BACKGROUND:Chronic antigenic stimulation may initiate non-Hodgkin (NHL) and Hodgkin lymphoma (HL) development. Antecedent, infection-related conditions have been associated, but evidence by lymphoproliferative subtype is limited. METHODS:From the US SEER-Medicare database, 44,191 NHL, 1832 HL and 200,000 population-ba...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/bjc.2014.173
更新日期:2014-05-27 00:00:00
abstract::In spite of the wide range of tumours successfully treated with 5-aminolevulinic acid mediated photodynamic therapy, the fact that 5-aminolevulinic acid has low lipid solubility, limits its clinical application. More lipophilic 5-aminolevulinic acid prodrugs and the use of liposomal carriers are two approaches aimed a...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/sj.bjc.6600144
更新日期:2002-03-04 00:00:00
abstract:OBJECTIVE:Detection of lymph node involvement in women with IB2-IIB cervical cancer could have a positive effect on survival. We set out to evaluate the incidence of pelvic and/or para-aortic lymph node involvement using the sentinel node (SN) biopsy and its impact on survival. METHODS:From 2002 to 2010, 66 women with...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/bjc.2011.541
更新日期:2012-01-03 00:00:00
abstract::Squamous cell carcinoma and adenocarcinoma of the oesophagus are cancers that develop from distinct epithelial sub-types; however, they are both related to chronic inflammation of differing aetiologies. Inflammation leads to somatically inherited genetic mutations altering control of the cell cycle, DNA replication an...
journal_title:British journal of cancer
pub_type: 杂志文章,评审
doi:10.1038/sj.bjc.6605126
更新日期:2009-07-07 00:00:00
abstract::Between 1946 and 1976 over 9,000 women with breast cancer were seen within one year of diagnosis at the A. Maxwell Evans Clinic (AMEC) in Vancouver, British Columbia. By 1978, 275 had a subsequent diagnosis of a second primary in the contralateral breast: 100 were diagnosed within 1 year, and 175 after 1 year of the f...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/bjc.1984.12
更新日期:1984-01-01 00:00:00
abstract:BACKGROUND:Ewing sarcoma is a paradigm of solid tumour -bearing chromosomal translocations resulting in fusion proteins that act as deregulated transcription factors. Ewing sarcoma translocations fuse the EWS gene with an ETS transcription factor, mainly FLI1. Most of the EWS-FLI1 target genes still remain unknown and ...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/sj.bjc.6605104
更新日期:2009-07-07 00:00:00
abstract::Human papillomavirus (HPV) is thought to cause some vulval squamous cell carcinomas (VSCC) by degrading p53 product. Evidence on whether HPV-negative VSCC results from p53 mutation is conflicting. We performed immunohistochemistry for p53 product on 52 cases of lone vulval intraepithelial neoplasia (VIN), 21 cases of ...
journal_title:British journal of cancer
pub_type: 杂志文章,meta分析,多中心研究
doi:10.1038/sj.bjc.6600677
更新日期:2003-01-27 00:00:00
abstract:BACKGROUND:We assessed the association between symptoms reported at breast cancer screening visits and interval cancers (ICs) in a prospective manner. METHODS:This population-based matched cohort study uses data of the Finnish National Breast Cancer Screening Programme that invites women aged 50-69 years old during 19...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/s41416-018-0308-2
更新日期:2018-11-01 00:00:00
abstract::Swedish population-based incidence and mortality rates for cancer of the uterine cervix, both in situ and invasive, during the period 1958 to 1981 were determined by means of a dynamic model. This new approach describes without any preconceptions the development of the disease as a sequential process over the stages c...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/bjc.1989.236
更新日期:1989-07-01 00:00:00
abstract::Bispecific antibodies (bsAb) are considered as promising tools for the elimination of disseminated tumour cells in a minimal residual disease situation. The bsAb-mediated recruitment of an immune effector cell in close vicinity of a tumour cell is thought to induce an antitumoural immune response. However, classical b...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1054/bjoc.2000.1237
更新日期:2000-07-01 00:00:00
abstract::HuR, a ubiquitously expressed member of the Hu protein family that binds and stabilizes an AU-rich element (ARE)-containing mRNAs, is known to shuttle between the nucleus and the cytoplasm via several export pathways. When normal cells were treated with heat shock, HuR was exported to the cytoplasm in a chromosome mai...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/sj.bjc.6605084
更新日期:2009-06-16 00:00:00
abstract::The vascular architecture of four different tumour cell lines (CaX, CaNT, SaS, HEC-1B) transplanted subcutaneously in mice was examined by means of microvascular corrosion casting in order to determine whether there is a characteristic vascular pattern for different tumour types and whether it differs significantly fr...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/sj.bjc.6690416
更新日期:1999-05-01 00:00:00
abstract::The aim of the study was to evaluate efficacy and tolerance of epirubicin and gemcitabine as first-line chemotherapy in patients with advanced non-small-cell lung cancer. A phase I study was performed with the combination of escalating doses of epirubicin intravenously on day 1 and a fixed dose of gemcitabine on days ...
journal_title:British journal of cancer
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1054/bjoc.1999.1003
更新日期:2000-02-01 00:00:00
abstract:BACKGROUND:Tumoural interstitial hypertension, possibly modulated by platelet-derived and vascular endothelial growth factor receptors (PDGFR and VEGFR), may mediate resistance to chemotherapy. METHODS:Forty-eight patients with advanced solid tumours received oral PDGFR inhibitor CP-868,596 (60-100 mg twice daily (BID...
journal_title:British journal of cancer
pub_type: 杂志文章,多中心研究
doi:10.1038/sj.bjc.6605941
更新日期:2010-11-09 00:00:00
abstract::In an Italian case-control study of oral cancer, number of missing teeth and other aspects of dental care were similar, but the general condition of the mouth, as indicated by gum bleeding, tartar deposits and mucosal irritation, was worse among oral cancer cases than controls. No differences were detected in sexual p...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1054/bjoc.2000.1398
更新日期:2000-11-01 00:00:00
abstract::The work presented here has concerned the study of early, as well as late, enzymic changes occurring during diethylnitrosamine-induced hepatocarcinogenesis and liver regeneration after partial hepatectomy in comparison with normal liver differentiation. Rank correlation analysis of the enzyme data suggested a step-wis...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/bjc.1983.222
更新日期:1983-10-01 00:00:00
abstract:BACKGROUND:The arachidonic acid metabolite 12(S)-HETE is suspected to enhance metastatic spread by inducing cancer cell- and lymph endothelial cell (LEC) motility. However, the molecular mechanisms leading to 12(S)-HETE-triggered cell migration are still elusive. METHODS:To delineate the signalling pathways involved i...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/bjc.2016.201
更新日期:2016-07-26 00:00:00
abstract::The NCA (nonspecific cross-reacting antigen) was assayed in sera of patients with chronic myeloid leukaemia (CML). It was elevated to a mean value of 145·6 ng/ml (± 104·4 ng/ml) compared to 37·8 ng/ml (± 14·6 ng/ml) the sera of normal subjects. Patients with active disease generally had higher serum NCA levels than th...
journal_title:British journal of cancer
pub_type: 杂志文章
doi:10.1038/bjc.1982.269
更新日期:1982-11-01 00:00:00