Tracheal intubating conditions using propofol and remifentanil target-controlled infusions.

Abstract:

:Using target-controlled infusions (TCI) we aimed to determine the most appropriate dose of remifentanil required for intubation, using a steady effect-site concentration of propofol and without the use of neuromuscular blocking drugs. Sixty ASA III patients presenting for elective surgery were randomly allocated to one of three groups. Anaesthesia was induced in all patients using a target-controlled infusion of propofol 6.5 microg x ml(-1). This was reduced to 3 microg x ml(-1) after 1 min. Each group received a different TCI of remifentanil, 19, 15 or 11 ng x ml(-1), which was reduced to 10, 8 or 6 ng x ml(-1), respectively, after 1 min. Laryngoscopy and intubation were attempted at 4 min. Laryngoscopy and ease of intubation were assessed using a standard scoring system. Intubation was considered satisfactory in 75% of patients in groups 1 and 2 and 35% of patients in group 3. Intubation was successful in 20/20, 19/20 and 15/20 patients in groups 1, 2 and 3, respectively. Pulse oximetry, heart rate and noninvasive arterial pressure were measured pre-induction, and at intervals until after laryngoscopy and intubation. Mean arterial pressure (MAP) and heart rate decreased following induction of anaesthesia in all groups, which was statistically significant. Following laryngoscopy, MAP and heart rate increased, but were significantly less than the corresponding baseline values.

journal_name

Anaesthesia

journal_title

Anaesthesia

authors

Troy AM,Huthinson RC,Easy WR,Kenney GN

doi

10.1046/j.1365-2044.2002.02624_3.x

subject

Has Abstract

pub_date

2002-12-01 00:00:00

pages

1204-7

issue

12

eissn

0003-2409

issn

1365-2044

journal_volume

57

pub_type

临床试验,杂志文章,随机对照试验
  • A combined high frequency oscillator and intermittent positive pressure ventilator.

    abstract::A high frequency oscillator and its interface with the Siemens 900C ventilator form a combined high frequency oscillator and intermittent positive pressure ventilator. This combined high frequency ventilator is designed for use in selected cases of refractory hypoxaemia. ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1995.tb15114.x

    authors: Raphael JH,Atkinson I,Bexton MD

    更新日期:1995-07-01 00:00:00

  • The association between peri-operative acute risk change (ARC) and long-term survival after cardiac surgery.

    abstract::Acute risk change has been described as the difference in calculated mortality risk between the pre-operative and postoperative periods of cardiac surgery. We aimed to assess whether this was associated with long-term survival after cardiac surgery. We retrospectively analysed 22,570 cardiac surgical patients, with mi...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.13967

    authors: Coulson TG,Bailey M,Reid CM,Tran L,Mullany DV,Smith JA,Pilcher D

    更新日期:2017-12-01 00:00:00

  • Pharmacological characteristics and side effects of a new galenic formulation of propofol without soyabean oil.

    abstract::We compared the pharmacokinetics, pharmacodynamics and safety profile of a new galenic formulation of propofol (AM149 1%), which does not contain soyabean oil, with a standard formulation of propofol (Disoprivan 1%). In a randomised, double-blind, cross-over study, 30 healthy volunteers received a single intravenous b...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1365-2044.2003.03345.x

    authors: Paul M,Dueck M,Kampe S,Fruendt H,Kasper SM

    更新日期:2003-11-01 00:00:00

  • Pulmonary embolism. Prophylaxis diagnosis and treatment.

    abstract::The natural history diagnosis and immediate treatment of patients suffering from pulmonary embolism has been discussed. Anaesthetists should use their influence to bring about a high standard of prophylactic care against deep venous thrombosis and consequently of pulmonary embolism. They are likely to be involved in t...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1976.tb11905.x

    authors: Price DG

    更新日期:1976-09-01 00:00:00

  • A systematic review of peri-operative melatonin.

    abstract::We systematically reviewed randomised controlled trials of peri-operative melatonin. We included 24 studies of 1794 participants that reported eight peri-operative outcomes: anxiety; analgesia; sleep quality; oxidative stress; emergence behaviour; anaesthetic requirements; steal induction; and safety. Compared with pl...

    journal_title:Anaesthesia

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/anae.12717

    authors: Andersen LP,Werner MU,Rosenberg J,Gögenur I

    更新日期:2014-10-01 00:00:00

  • Serious complications with dextran-70 despite hapten prophylaxis. Is it best avoided prior to delivery?

    abstract::Dextran is used clinically for plasma volume expansion, improvement of blood flow and thromboprophylaxis, but has been associated with untoward side effects. Immunoprophylaxis with dextran I (hapten), before the infusion of dextran-70, has reduced the incidence of serious dextran-induced anaphylactoid reactions. We re...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1991.tb09916.x

    authors: Berg EM,Fasting S,Sellevold OF

    更新日期:1991-12-01 00:00:00

  • Effect of xenon anaesthesia on accuracy of cardiac output measurement using partial CO2 rebreathing.

    abstract::Cardiac output (CO) determination based on partial CO(2) rebreathing has recently been introduced into clinical practice. The determination of flow is crucial for exact CO readings and the physical properties of xenon, i.e. high density and viscosity, may influence flow readings. This study compared echocardiography-d...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2004.03897.x

    authors: Bein B,Hanne P,Hanss R,Renner J,Weber B,Steinfath M,Scholz J,Tonner PH

    更新日期:2004-11-01 00:00:00

  • Peri-operative stroke in general surgical patients.

    abstract::The incidence and aetiology of peri-operative stroke in patients undergoing general surgical procedures are reviewed. Some general recommendations on the peri-operative anaesthetic management of these patients are summarised. ...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2044.1997.136-az0129.x

    authors: Kam PC,Calcroft RM

    更新日期:1997-09-01 00:00:00

  • Vecuronium induced neuromuscular blockade. The effect of increasing dose on speed of onset.

    abstract::The speed of onset of neuromuscular blockade was measured for increasing doses of vecuronium. Onset times were found to be shorter with larger doses, up to a limit of ED95 X 3 (0.15 mg/kg). Thereafter, increasing the dose, even up to ED95 X 8 (0.4 mg/kg), did not appreciably shorten the time to full neuromuscular bloc...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1986.tb13217.x

    authors: Casson WR,Jones RM

    更新日期:1986-04-01 00:00:00

  • Randomised double-blinded comparison of phenylephrine vs ephedrine for maintaining blood pressure during spinal anaesthesia for non-elective Caesarean section*.

    abstract:SUMMARY:In a randomised, double-blinded study, we compared boluses of phenylephrine 100 microg with ephedrine 10 mg for treating hypotension (systolic blood pressure < 100 mmHg) in 204 patients having non-elective Caesarean section under spinal anaesthesia. Umbilical arterial (UA) and venous (UV) pH and base excess wer...

    journal_title:Anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.2008.05635.x

    authors: Ngan Kee WD,Khaw KS,Lau TK,Ng FF,Chui K,Ng KL

    更新日期:2008-12-01 00:00:00

  • Effects of the cervical collar on cerebrospinal fluid pressure.

    abstract::We investigated the hypothesis that cervical collars might compress the internal jugular veins and raise intracranial pressure in head-injured patients. In a randomised, single-blind, crossover study of nine patients scheduled for elective spinal anaesthesia the cerebrospinal fluid pressure in the lumbar subarachnoid ...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1994.tb03482.x

    authors: Raphael JH,Chotai R

    更新日期:1994-05-01 00:00:00

  • The effect of needle dimensions and infusion rates on injection pressures in regional anaesthesia needles: a bench-top study.

    abstract::Animal studies have shown that injection pressures > 75 kPa indicate probable intrafascicular needle tip position. This study describes the flow/pressure characteristics of seven common needle systems. A syringe pump delivered flow rates of 5, 6.67, 10, 13.3, 15 and 20 ml.min(-1) through these needle systems, while ke...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.12869

    authors: Patil JJ,Ford S,Egeler C,Williams DJ

    更新日期:2015-02-01 00:00:00

  • Addressing priorities for surgical research in Africa: implementation of a multicentre cloud-based peri-operative registry in Ethiopia.

    abstract::In resource-constrained settings, where inequalities in access to and quality of surgical care results in excess mortality, peri-operative care registries are uncommon. A south-south collaboration supported the implementation of a context specific, clinician-led, multicentre real-time peri-operative registry in Ethiop...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.15394

    authors: Network for Peri-operative Critical care (N4PCc)*.

    更新日期:2021-01-25 00:00:00

  • Rapid sequence induction: a questionnaire survey of its routine conduct and continued management during a failed intubation.

    abstract::Two hundred and ten obstetric anaesthetists completed a questionnaire assessing how they would perform a rapid sequence induction of anaesthesia for a Caesarean section and their continued management during a failed tracheal intubation. The survey revealed considerable variation in the timing and application of cricoi...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1046/j.1365-2044.1999.00738.x

    authors: Thwaites AJ,Rice CP,Smith I

    更新日期:1999-04-01 00:00:00

  • A systematic review and meta-analysis of the i-gel® vs laryngeal mask airway in children.

    abstract::We systematically reviewed randomised controlled trials of the i-gel® vs different types of laryngeal mask airway in children. We included nine studies. There was no evidence for differences in: rate of insertion at first attempt; insertion time; ease of insertion; or gastric tube insertion. The mean (95% CI) orophary...

    journal_title:Anaesthesia

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/anae.12746

    authors: Choi GJ,Kang H,Baek CW,Jung YH,Woo YC,Cha YJ

    更新日期:2014-11-01 00:00:00

  • Forum. The use of atracurium besylate for laparoscopy.

    abstract::An anaesthetic technique is described for laparoscopy using an intravenous induction, atracurium 0.2 mg/kg for muscle relaxation and intermittent positive pressure ventilation of the lungs with nitrous oxide and oxygen. It was found to be a suitable and simple technique. Recovery of spontaneous ventilation was achieve...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1365-2044.1984.tb07243.x

    authors: Sleigh JW,Matheson KH,Boys JE

    更新日期:1984-03-01 00:00:00

  • Adverse reaction to methohexitone and gallamine.

    abstract::A case is presented in which a patient developed an acute anaphylactoid reaction after receiving methohexitone and gallamine for the induction of anaesthesia. The problem of eliciting the responsible agent is discussed, which comments on the method of treatment and preventative measures. ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1981.tb08597.x

    authors: Harrison GR,Thompson ID

    更新日期:1981-01-01 00:00:00

  • Pulmonary arterio-venous fistula. A shunt equation exercise during thoracotomy.

    abstract::A report is given of a patient with multiple bilateral pulmonary arterio-venous fistulae who underwent right thoracotomy for this condition. Blood-gas studies before and during surgery showed that the arterio-venous oxygen content differences of 1-16-1-34 mmol/l were less than normal, and the calculated venous admixtu...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1977.tb10081.x

    authors: Purcell GR,Manners JM,Cockburn JS

    更新日期:1977-09-01 00:00:00

  • Relationship between the inability to climb two flights of stairs and outcome after major non-cardiac surgery: implications for the pre-operative assessment of functional capacity.

    abstract::Functional capacity is an integral component of the pre-operative evaluation of the cardiac patient for non-cardiac surgery. Stair climbing capacity has peri-operative prognostic importance. It may predict survival after lung resection and complications after major non-cardiac surgery. However, stair climbing cannot d...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2044.2005.04181.x

    authors: Biccard BM

    更新日期:2005-06-01 00:00:00

  • Differential flow from multihole epidural catheters.

    abstract::The pressures used in vivo to administer epidural doses of local anaesthetic were recorded for 16- and 18-gauge multihole catheters. Observations were made on 10 patients in labour for each catheter gauge. The pressure range for the 16-gauge catheters was 39.9-266 kPa, with a mean of 167.2 kPa, and for 18-gauge, a ran...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1988.tb05605.x

    authors: Power I,Thorburn J

    更新日期:1988-10-01 00:00:00

  • Spinal anaesthesia for urological surgery. A survey of failure rate, postdural puncture headache and patient satisfaction.

    abstract::A survey was conducted on 100 consecutive patients who underwent spinal anaesthesia in our urology operating theatres. Details of the spinal technique were recorded in the operating theatre. In 25% of patients, more than one attempt at subarachnoid puncture was required and 16% of this group went on to require general...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1992.tb03161.x

    authors: Harrison DA,Langham BT

    更新日期:1992-10-01 00:00:00

  • Blood disoprofol levels in anesthetised patients. Correlation of concentrations after single or repeated doses with hypnotic activity.

    abstract::The blood concentrations of disoprofol (Diprivan) after single intravenous doses of 1, 2 or 3 mg/kg have been examined in a subpopulation from previously reported clinical studies. The linear relationship between sleep time and dose could be explained by the linearity of the pharmacokinetics at these doses. After a si...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1982.tb01223.x

    authors: Adam HK,Kay B,Douglas EJ

    更新日期:1982-05-01 00:00:00

  • Evidence for benefit vs novelty in new intubation equipment.

    abstract::A myriad of new intubation equipment has been introduced commercially since the appearance of Macintosh/Miller blades in the 1940s. We review the role of devices that are relevant to current clinical practice based on their presence in the scientific literature. The comparative performance of new vs traditional direct...

    journal_title:Anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2044.2011.06935.x

    authors: Behringer EC,Kristensen MS

    更新日期:2011-12-01 00:00:00

  • Safety and efficacy of rescue flexible bronchoscopic intubation using the Bentson floppy-tip guidewire via a supraglottic airway in critically ill children.

    abstract::Difficulty in tracheal intubation in paediatric intensive care patients is associated with increased morbidity and mortality. Delays to intubation and interruption to oxygenation and ventilation are poorly tolerated. We developed a safe and atraumatic tracheal intubation technique. A floppy-tipped guidewire and airway...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/anae.14008

    authors: Cross D,Nyman A,James P,Durward A

    更新日期:2017-11-01 00:00:00

  • Validation of a pre-anaesthetic screening questionnaire.

    abstract::We developed a screening questionnaire to be used by nurses to decide which patients should see an anaesthetist for further evaluation before the day of surgery. Our objective was to measure the accuracy of responses to the questionnaire. Agreement between questionnaire responses and the anaesthetist's assessment was ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1046/j.1365-2044.2003.03335.x

    authors: Hilditch WG,Asbury AJ,Jack E,McGrane S

    更新日期:2003-09-01 00:00:00

  • Evaluation of a new continuous cardiac output monitor in off-pump coronary artery surgery.

    abstract::We evaluated a new, ultra-fast response continuous cardiac output monitor in 34 adult patients undergoing off-pump coronary artery bypass graft surgery. Cardiac output was measured with the TruCCOMS continuous cardiac output monitor (Aortech International plc, Lanarkshire, UK), using triplicate cold bolus thermodiluti...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.2004.03668.x

    authors: Leather HA,Vuylsteke A,Bert C,M'Fam W,Segers P,Sergeant P,Vandermeersch E,Wouters PF

    更新日期:2004-04-01 00:00:00

  • Immediate care of cardiac emergencies.

    abstract::The emergency treatment of serious disorders of cardiac rhythm, left heart failure, cardiogenic shock, and cyanotic attacks is discussed. The article is intended for medical practitioners without special cardiological experience. ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1976.tb11866.x

    authors: Chamberlain DA,Williams JH

    更新日期:1976-07-01 00:00:00

  • The estimation of inspired desflurane concentration in a low-flow system.

    abstract::We have examined the predictability of inspired desflurane concentration during low-flow anaesthesia using a to-and-fro breathing system. Twenty-two adult patients requiring mechanical ventilation of the lungs during surgery took part in the study. Using a fresh gas flow of 1 l.min-1, the ratio of inspired desflurane ...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1111/j.1365-2044.1996.tb14953.x

    authors: Gowrie-Mohan S,Muralitharan V,Lockwood GG

    更新日期:1996-10-01 00:00:00

  • Cerebral and regional organ perfusion in pigs during xenon anaesthesia.

    abstract::Little is known about the haemodynamic effects of inhaled xenon on regional organ perfusion. The aim of this study was to investigate the effect of 79% xenon ventilation on organ perfusion in pigs. We investigated 10 pigs, which were randomly allocated to receive either xenon 79% or total intravenous anaesthesia (TIVA...

    journal_title:Anaesthesia

    pub_type: 杂志文章

    doi:10.1046/j.1365-2044.2001.02322.x

    authors: Schmidt M,Marx T,Kotzerke J,Lüderwald S,Armbruster S,Topalidis P,Schirmer U,Reinelt H

    更新日期:2001-12-01 00:00:00

  • A comparison of different modes of noninvasive ventilatory support: effects on ventilation and inspiratory muscle effort.

    abstract::The aims of noninvasive ventilation include the correction of hypoventilation and unloading of inspiratory muscles. Volume cycled flow generators, bi-level positive airway pressure and continuous positive airway pressure techniques have all been used with face and nasal masks. We have compared these modes of ventilato...

    journal_title:Anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2044.1994.tb14173.x

    authors: Elliott MW,Aquilina R,Green M,Moxham J,Simonds AK

    更新日期:1994-04-01 00:00:00