Abstract：
PURPOSES:To compare the claudication distances between men and women patients with peripheral arterial disease (PAD), and to determine whether sex differences in claudication pain persisted after controlling for potential confounders such as demographic, functional, and physiological measures. METHODS:A total of 488 men and 72 women functionally limited by intermittent claudication were evaluated. Patients were characterized on PAD-specific measures consisting of ankle/brachial index (ABI) and treadmill claudication distances, physical function measures consisting of ambulatory function, monitored physical activity, balance, and strength, and demographic measures obtained during a medical history. RESULTS:Initial claudication distance (ICD) was 33% shorter ( = 0.024) in women than in men (126 +/- 22 vs 189 +/- 13 m; mean +/- SEM), and absolute claudication distance (ACD) was 23% shorter ( = 0.022) in women (313 +/- 43 vs 407 +/- 18 m). These differences were present despite similar ( = 0.440) ABI values between women (0.63 +/- 0.02) and men (0.62 +/- 0.01). Peak oxygen uptake ( = 0.043) and self-perceived stair climbing ability ( = 0.020) were different between men and women, and were independently related to ICD (multiple R = 0.57, < 0.001) and to ACD (multiple R = 0.71, < 0.001). The sex differences in ICD ( = 0.524) and ACD ( = 0.722) were no longer present after controlling for peak oxygen uptake and self-perceived stair climbing ability. CONCLUSION:Shorter treadmill claudication distances in women with PAD were explained by their lower cardiopulmonary fitness and poorer self-perceived ability to climb stairs than compared with men. Therefore, women with intermittent claudication represent a subgroup of PAD patients who should receive high priority for exercise rehabilitation to improve physical function.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Gardner AWdoi
10.1097/00005768-200211000-00001subject
Has Abstractpub_date
2002-11-01 00:00:00pages
1695-8issue
11eissn
0195-9131issn
1530-0315journal_volume
34pub_type
杂志文章abstract：:Potential physiological, anthropometric, and training determinants of running economy (RE) were studied in a heterogeneous group of habitual distance runners (N = 188, 119 males, 69 females). RE was measured as VO2 (ml.kg-1.min-1) during level treadmill running at 161 m.min-1 (6 mph) (VO2-6). Examined as potential det...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：:Nine men participated in an exercise program (five days a week for 10 weeks) that was designed to strengthen the quadriceps muscles. This study was undertaken to determine if heavy resistance training results in an increase in endurance, Vo2max and whether the differences that are normally observed during bicycle and ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：PURPOSE:Cardiac aldosterone might be involved in the deleterious effects of nandrolone decanoate (ND) on the heart. Therefore, we investigated the involvement of cardiac aldosterone, by the pharmacological block of AT1 or mineralocorticoid receptors, on cardiac hypertrophy and fibrosis. METHODS:Male Wistar rats were r...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318217e8b6
更新日期：2011-10-01 00:00:00
abstract：INTRODUCTION:Gastroesophageal reflux disease is a disorder in which gastric contents move from stomach to esophagus. Exercise is a recognized contributing factor to reflux in healthy volunteers and is reported to be proportional to exercise intensity and the type of exercise. Our aim was to explore changes in physiolog...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.MSS.0000064937.99001.56
更新日期：2003-05-01 00:00:00
abstract：PURPOSE:This study aimed to examine the influence of sagittal plane trunk posture on lower extremity energetics during running. METHODS:Forty asymptomatic recreational runners (20 males and 20 females) ran overground at a speed of 3.4 m·s(-1). Sagittal plane trunk kinematics and lower extremity kinematics and energeti...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000436
更新日期：2015-03-01 00:00:00
abstract：:Exercise represents the primary countermeasure used during spaceflight to maintain or restore maximal aerobic capacity (VO2max), musculoskeletal structure, and orthostatic function. However, no single exercise or combination of prescriptions has proven entirely effective in restoring cardiovascular and musculoskeletal...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：10.1097/00005768-199608000-00010
更新日期：1996-08-01 00:00:00
abstract：:The kinetics of gas exchange at the on-transient of exercise are appreciably slowed in older individuals. Eight older men (72 yr) completed 6 months of aerobic cycle training. Ventilation and gas exchange kinetics were determined at the onset of a below threshold (ventilatory threshold, V(E)T) square wave exercise fun...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：PURPOSE:The purpose of this study was to identify electromyographic (EMG) differences in the latent muscle reaction timing (LMRT) of the rotator cuff between trained overhead throwers and control subjects in response to sudden internal rotation perturbation (P < or = 0.05). METHODS:Subjects included 15 trained overhea...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199910000-00006
更新日期：1999-10-01 00:00:00
abstract：PURPOSE:Heart transplant recipients (HTx) have a high prevalence of hypertension. Although exercise training promotes blood pressure (BP) reduction in HTx, the effects of a single exercise bout are unknown. Thus, we analyzed the acute effects of heated water-based exercise (HEx) versus land-based exercise (LEx) on ambu...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0000000000000846
更新日期：2016-05-01 00:00:00
abstract：PURPOSE:To estimate the prevalence of metabolic syndrome and insulin resistance in a cohort of Division 1 collegiate football players. METHODS:Ninety football players were evaluated in a cross-sectional study to estimate the prevalence of metabolic syndrome, insulin resistance, and associated risk factors. Obesity was...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181abdfec
更新日期：2009-12-01 00:00:00
abstract：:We compared physiological and perceptual responses to non-weight bearing (cycle) and weight bearing (treadmill) exercise in 16 sedentary women throughout a normal term pregnancy. Subjects were recruited late in the first trimester (less than 13 wk gestation) and were studied at 4 wk intervals throughout pregnancy and ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：PURPOSE:the objective of this study was to characterize the biomechanical effects of step rate modification during running on the hip, knee, and ankle joints so as to evaluate a potential strategy to reduce lower extremity loading and risk for injury. METHODS:three-dimensional kinematics and kinetics were recorded fro...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181ebedf4
更新日期：2011-02-01 00:00:00
abstract：PURPOSE:This is a case study of an aerobically trained, multisport, female athlete (age = 39) diagnosed with stage IIIc human epidermal growth factor receptor 2 positive breast cancer. The focus of the study is on measures of cardiorespiratory fitness (V˙O2peak) through the course of cancer therapy. METHODS:A symptom-...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000987
更新日期：2016-10-01 00:00:00
abstract：PURPOSE:Heart rate variability (HRV) indices are powerful independent prognostic factors of cardiovascular events and all cause mortality in patients with chronic heart failure (CHF). This study evaluates the influence of lifestyle on HRV in CHF patients. METHODS:Thirty-nine CHF patients (33 men, ischemic/dilated card...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.mss.0000174881.68546.ec
更新日期：2005-08-01 00:00:00
abstract：PURPOSE:Despite the growing research interest in vascular adaptations to exercise training over the last few decades, it remains unclear whether microvascular function in healthy subjects can be further improved by regular training. Herein, we sought to systematically review the literature and determine whether microva...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,meta分析,评审
doi：10.1249/MSS.0000000000000567
更新日期：2015-07-01 00:00:00
abstract：:The effect of glucose polymer (GP) ingestion upon endurance performance during walking exercise at 45% VO2max was examined. Also, performance on a battery of psychomotor tests was assessed to determine if exhaustion from endurance exercise was related to central nervous system dysfunction. Ten trained male subjects in...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：PURPOSE:To determine whether quantitative methods could separate golfers with a possible dystonic cause of the "yips" from those that appear to be nondystonic. METHODS:Twenty-seven golfers completed 10 two-handed and 10 right hand-only putts. Surface EMG assessed forearm muscle co-contraction and motion detectors moni...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001687
更新日期：2018-11-01 00:00:00
abstract：:Twelve college-age men exercised on a bicycle ergometer to VO2max and at 60, 70, and 80% VO2max for 30 min to determine the effects of exercise intensity on plasma beta-endorphin (B-EP). The time course for alterations in B-EP and the relationship to lactate were also examined. Following the VO2max test, the three sub...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：PURPOSE:This study was conducted to determine if fifth-grade students who walked or bicycled to school on a regular basis were more physically active than those that did not. METHODS:The sample consists of 219 fifth-grade students (10.3 +/- 0.6 yr, 44% male, 58% minority) from eight randomly selected urban and suburba...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.mss.0000179102.17183.6b
更新日期：2005-12-01 00:00:00
abstract：PURPOSE:To investigate the effects of blood flow restriction (BFR) combined with electrical muscle stimulation (EMS) on skeletal muscle mass and strength during a period of limb disuse. METHODS:Thirty healthy participants (22 ± 3 years; 23 ± 3 kg·m) were randomly assigned to either: control (CON; n=10), BFR alone (BFR...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002544
更新日期：2020-10-22 00:00:00
abstract：PURPOSE:This study aimed to determine the effect of acute exercise on the proliferation and expression of activation markers on T-lymphocytes. METHODS:Seventeen well-trained male endurance runners completed 60 min of treadmill running at 95% of ventilatory threshold and a resting, no exercise, control session at the s...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.MSS.0000058361.82096.26
更新日期：2003-04-01 00:00:00
abstract：PURPOSE:The present study assessed the factorial validity and gender invariance of the Social Physique Anxiety Scale (SPAS) using a sample of young adolescents. Existing SPAS 12-item, one- and two-factor and truncated, one-factor (i.e., nine-item and seven-item) measurement models reported in the adult literature were ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.mss.0000117111.76228.bf
更新日期：2004-03-01 00:00:00
abstract：PURPOSE:Physical activity plays an important role in the prevention of many serious diseases. To develop targeted strategies that encourage physical activity, knowledge of stability of physical activity levels over time is essential. The aim of this study was to examine tracking of leisure time physical activity in adu...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3182084562
更新日期：2011-07-01 00:00:00
abstract：:It is commonly believed that exposure to cold environmental temperatures depresses immune function and increases the risk for infection. This review paper will 1) present an overview of human physiological responses to cold exposure, 2) present the human studies examining the effects of cold exposure on immune respons...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：10.1097/00005768-200212000-00023
更新日期：2002-12-01 00:00:00
abstract：:We suggest a mechanism by which blood volume changes might explain the hypotension that, after space flight, often accompanies the return to normal gravity. Upon entering microgravity, peripheral veins may collapse and, because of volume redistribution, raise the pressure in the central venous compartment. After some ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199610000-00029
更新日期：1996-10-01 00:00:00
abstract：PURPOSE:To study the ventilatory effects of closely monitored cycle ergometer conditioning (HR target, 145-150 beats x min(-1); 25 min/session; three sessions per week) during the second and third pregnancy trimesters (TMs) in healthy human pregnancy. METHODS:Subjects were 27 previously sedentary pregnant women (exerc...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199801000-00004
更新日期：1998-01-01 00:00:00
abstract：PURPOSE:To compare the cardiovascular reactivity response to mental challenge of aerobically trained and untrained preadolescent boys. METHODS:Heart rate (HR) and blood pressure, as well as stroke volume, total peripheral resistance, rate pressure product, and cardiac contractility response in 15 aerobically trained (...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
doi：10.1249/01.MSS.0000078935.78895.8E
更新日期：2003-08-01 00:00:00
abstract：:Studies using wearable sensors to measure posture, physical activity (PA), and sedentary behavior typically use a single sensor worn on the ankle, thigh, wrist, or hip. Although the use of single sensors may be convenient, using multiple sensors is becoming more practical as sensors miniaturize. PURPOSE:We evaluated ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002306
更新日期：2020-08-01 00:00:00
abstract：INTRODUCTION:Muscle force production is usually impaired in people with spinal cord injury (SCI). The use of high-intensity neuromuscular electrical stimulation (NMES) strength training can help promote metabolically active lean muscle mass and, thus, increase muscle mass and improve physical health and quality of life...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001637
更新日期：2018-09-01 00:00:00
abstract：PURPOSE AND METHODS:The isovolumic contractile responsiveness of left ventricular (LV) myocardium to altered extracellular [Ca2+], [Na+], and pacing frequency was examined using perfused hearts (37 degrees C) isolated from sedentary (SED) and treadmill-trained (TR) adult female rats. RESULTS:The suppressive effect of ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199810000-00006
更新日期：1998-10-01 00:00:00
