Transluminal stent-graft placements for the treatments of acute onset and chronic aortic dissections.

abstract：BACKGROUND:Induction of matrix metalloproteinases (MMPs) contributes to adverse remodeling after myocardial infarction (MI). Whether a region- and type-specific distribution of MMPs occurs within the post-MI myocardium remained unknown. METHODS AND RESULTS:Ten sheep were instrumented with a sonomicrometry array to mea...

journal_title：Circulation

authors： Wilson EM,Moainie SL,Baskin JM,Lowry AS,Deschamps AM,Mukherjee R,Guy TS,St John-Sutton MG,Gorman JH 3rd,Edmunds LH Jr,Gorman RC,Spinale FG

更新日期：2003-06-10 00:00:00

abstract：BACKGROUND:Heparin-induced thrombocytopenia (HIT) is an immune-mediated syndrome caused by heparin. Complications range from thrombocytopenia to thrombocytopenia with thrombosis. We report a prospective, historical- controlled study evaluating the efficacy and safety of argatroban, a direct thrombin inhibitor, as antic...

journal_title：Circulation

authors： Lewis BE,Wallis DE,Berkowitz SD,Matthai WH,Fareed J,Walenga JM,Bartholomew J,Sham R,Lerner RG,Zeigler ZR,Rustagi PK,Jang IK,Rifkin SD,Moran J,Hursting MJ,Kelton JG,ARG-911 Study Investigators.

更新日期：2001-04-10 00:00:00

abstract：BACKGROUND:Little information is available regarding the occurrence of perioperative and late cardiac events in women with vascular disease. The current study was performed to examine whether sex-specific differences exist in these outcomes in a large population of vascular surgery patients and to determine the value o...

journal_title：Circulation

authors： Hendel RC,Chen MH,L'Italien GJ,Newell JB,Paul SD,Eagle KA,Leppo JA

更新日期：1995-02-15 00:00:00

abstract：BACKGROUND:Metformin is first-line therapy for type 2 diabetes mellitus, although its effects on the cardiovascular system are unproved. METHODS:In this post hoc analysis, patients in SAVOR-TIMI 53 (Saxagliptin and Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus) with baseline biomarker samples (n=12...

journal_title：Circulation

authors： Bergmark BA,Bhatt DL,McGuire DK,Cahn A,Mosenzon O,Steg PG,Im K,Kanevsky E,Gurmu Y,Raz I,Braunwald E,Scirica BM,SAVOR-TIMI 53 Steering Committee and Investigators.

更新日期：2019-09-17 00:00:00

abstract：BACKGROUND:In patients with acute myocardial infarction (AMI), hyperglycemia predicts death, but the prognostic significance of hypoglycemia is controversial. METHODS AND RESULTS:We evaluated the prognostic significance of hypoglycemia and hyperglycemia in 30 536 AMI patients in a post hoc analysis of 2 large trials o...

journal_title：Circulation

authors： Goyal A,Mehta SR,Díaz R,Gerstein HC,Afzal R,Xavier D,Liu L,Pais P,Yusuf S

更新日期：2009-12-15 00:00:00

abstract：:While spatial asynergy at end-systole has been well characterized in patients with coronary artery disease, assessment of regional asynchrony has been hampered by technical constraints. We developed a computer-assisted method for analyzing regional asynchrony from the equilibrium (ECG-gated) radionuclide ventriculogra...

journal_title：Circulation

authors： Holman BL,Wynne J,Idoine J,Neill J

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:In this study we tested the hypothesis that atrial fibrillation (AF) causes electrophysiological changes of the atrial myocardium which might explain the progressive nature of the arrhythmia. METHODS AND RESULTS:Twelve goats were chronically instrumented with multiple electrodes sutured to the epicardium of...

journal_title：Circulation

authors： Wijffels MC,Kirchhof CJ,Dorland R,Allessie MA

更新日期：1995-10-01 00:00:00

abstract：:The healthcare system is undergoing a transition from paying for volume to paying for value. Clinicians, as well as public and private payers, are beginning to implement alternative delivery and payment models, such as the patient-centered medical home, accountable care organizations, and bundled payment arrangements....

journal_title：Circulation

authors： Bufalino VJ,Berkowitz SA,Gardner TJ,Piña IL,Konig M,AHA Expert Panel on Payment and Delivery System Reform.

更新日期：2017-08-15 00:00:00

abstract：BACKGROUND:The maintenance and termination of reentry arrhythmias are determined by tissue properties such as refractoriness and conduction velocity. Although the effects of Na(+) and K(+) channel block on electrophysiological properties and defibrillation threshold (DFT) have been studied, little is known about the ef...

journal_title：Circulation

authors： Qi X,Varma P,Newman D,Dorian P

更新日期：2001-09-25 00:00:00

abstract：BACKGROUND:Cardiac hypertrophy and subsequent heart failure triggered by chronic hypertension represent major challenges for cardiovascular research. Beyond neurohormonal and myocyte signaling pathways, growing evidence suggests inflammatory signaling pathways as therapeutically targetable contributors to this process....

journal_title：Circulation

authors： Heymans S,Corsten MF,Verhesen W,Carai P,van Leeuwen RE,Custers K,Peters T,Hazebroek M,Stöger L,Wijnands E,Janssen BJ,Creemers EE,Pinto YM,Grimm D,Schürmann N,Vigorito E,Thum T,Stassen F,Yin X,Mayr M,de Windt LJ,

更新日期：2013-09-24 00:00:00

abstract：:When acute myocardial infarction occurs in patients with hypertension and left ventricular hypertrophy (LVH), the incidence of sudden cardiac death increases markedly. Possible explanations include increased size of the occluded vascular bed secondary to more extensive atherosclerotic coronary vascular disease in the ...

journal_title：Circulation

authors： Koyanagi S,Eastham C,Marcus ML

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND:Oxygen administration is currently used in clinical medicine to improve peripheral oxygen delivery to tissues threatened by ischemia. However, conflicting results have been reported on the effects of oxygen in ischemic areas. This study was aimed at investigating the effects of 40% oxygen inhalation on the s...

journal_title：Circulation

authors： Bongard O,Bounameaux H,Fagrell B

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:The novel phosphate binder sevelamer has been shown to prevent the progression of aortic and coronary calcification in uremic patients. Whether it also decreases the progression of atheromatous plaques is unknown. The aim of our study was to examine the effect of sevelamer administration on the development o...

journal_title：Circulation

authors： Phan O,Ivanovski O,Nguyen-Khoa T,Mothu N,Angulo J,Westenfeld R,Ketteler M,Meert N,Maizel J,Nikolov IG,Vanholder R,Lacour B,Drüeke TB,Massy ZA

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Coronary artery disease (CAD) and myocardial infarction (MI) are caused in part by genetic factors. Recently, the MEF2A gene was linked to MI/CAD in a single pedigree with autosomal-dominant pattern of inheritance. In addition, genetic variants within the gene have been associated with MI in case-control set...

journal_title：Circulation

authors： Lieb W,Mayer B,König IR,Borwitzky I,Götz A,Kain S,Hengstenberg C,Linsel-Nitschke P,Fischer M,Döring A,Wichmann HE,Meitinger T,Kreutz R,Ziegler A,Schunkert H,Erdmann J

更新日期：2008-01-15 00:00:00

abstract：BACKGROUND:Activated protein C resistance due to factor V Leiden (FVL) is a common genetic risk factor for venous thrombosis in humans. Although the impact of FVL on the development of venous thrombosis is well established, its effect on arterial thrombosis and atherosclerosis is controversial. METHODS AND RESULTS:To ...

journal_title：Circulation

authors： Eitzman DT,Westrick RJ,Shen Y,Bodary PF,Gu S,Manning SL,Dobies SL,Ginsburg D

更新日期：2005-04-12 00:00:00

abstract：BACKGROUND:Myocardium irreversibly injured by ischemic stress must be efficiently repaired to maintain tissue integrity and contractile performance. Macrophages play critical roles in this process. These cells transform across a spectrum of phenotypes to accomplish diverse functions ranging from mediating the initial i...

journal_title：Circulation

authors： Cao DJ,Schiattarella GG,Villalobos E,Jiang N,May HI,Li T,Chen ZJ,Gillette TG,Hill JA

更新日期：2018-06-12 00:00:00

abstract：BACKGROUND:Factors leading differentially to the development of isolated diastolic (IDH), systolic-diastolic (SDH), and isolated systolic (ISH) hypertension are poorly understood. We examined the relations of blood pressure (BP) and clinical risk factors to the new onset of the 3 forms of hypertension. METHODS AND RES...

journal_title：Circulation

authors： Franklin SS,Pio JR,Wong ND,Larson MG,Leip EP,Vasan RS,Levy D

更新日期：2005-03-08 00:00:00

abstract：BACKGROUND:Diabetes is an independent risk factor for the development of neointimal hyperplasia and subsequent vein graft failure after coronary or peripheral artery bypass grafting. We evaluate a new mouse model of surgical vein grafting to investigate the mechanisms of neointimal formation in the setting of type 2 di...

journal_title：Circulation

authors： Salzberg SP,Filsoufi F,Anyanwu A,von Harbou K,Karlof E,Carpentier A,Dansky HM,Adams DH

更新日期：2006-07-04 00:00:00

abstract：BACKGROUND:It is recommended that comatose survivors of out-of-hospital cardiac arrest should be cooled to 32° to 34°C for 12 to 24 hours. However, the optimal level of cooling is unknown. The aim of this pilot study was to obtain initial data on the effect of different levels of hypothermia. We hypothesized that deepe...

journal_title：Circulation

authors： Lopez-de-Sa E,Rey JR,Armada E,Salinas P,Viana-Tejedor A,Espinosa-Garcia S,Martinez-Moreno M,Corral E,Lopez-Sendon J

更新日期：2012-12-11 00:00:00

abstract：BACKGROUND:Pulse pressure (PP) increases with age as a result of arterial stiffening and is a powerful predictor of cardiovascular disease. Type 1 diabetes is associated with excessive cardiovascular mortality and increased arterial stiffness. We examined whether the age-related blood pressure changes in type 1 diabeti...

journal_title：Circulation

authors： Rönnback M,Fagerudd J,Forsblom C,Pettersson-Fernholm K,Reunanen A,Groop PH,Finnish Diabetic Nephropathy (FinnDiane) Study Group.

更新日期：2004-08-31 00:00:00

abstract：BACKGROUND:Congestive heart failure (CHF) in humans is associated with a marked sympathoexcitation, including an augmented muscle sympathetic nerve activity (MSNA) in intraneural multiunit recordings. In the present study, single-unit recording was used to evaluate whether the firing properties of individual muscle vas...

journal_title：Circulation

authors： Macefield VG,Rundqvist B,Sverrisdottir YB,Wallin BG,Elam M

更新日期：1999-10-19 00:00:00

abstract：BACKGROUND:Cardiac mechanical restitution and relaxation restitution are thought to be physiological correlates of the recovery kinetics of Ca2+ release mechanisms and sequestration capacity of the sarcoplasmic reticulum (SR). Since congestive heart failure is characterized by abnormal intracellular Ca2+ handling, we s...

journal_title：Circulation

authors： Prabhu SD,Freeman GL

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Pulmonary arterial hypertension (PAH) remains a concern in patients with β-thalassemia major (TM) and intermedia (TI); however, studies evaluating its prevalence and risk factors using systematic confirmation on right heart catheterization are lacking. METHODS AND RESULTS:This was a multicenter cross-sectio...

journal_title：Circulation

authors： Derchi G,Galanello R,Bina P,Cappellini MD,Piga A,Lai ME,Quarta A,Casu G,Perrotta S,Pinto V,Musallam KM,Forni GL,Webthal Pulmonary Arterial Hypertension Group*.

更新日期：2014-01-21 00:00:00

abstract：BACKGROUND:Lymphatic network and chemokine-mediated signals are essential for leukocyte traffic during the proximal steps of alloimmune response. We aimed to determine the role of lymphatic vessels and their principal growth signaling pathway, vascular endothelial growth factor (VEGF)-C/D/VEGFR-3, during acute and chro...

journal_title：Circulation

authors： Nykänen AI,Sandelin H,Krebs R,Keränen MA,Tuuminen R,Kärpänen T,Wu Y,Pytowski B,Koskinen PK,Ylä-Herttuala S,Alitalo K,Lemström KB

更新日期：2010-03-30 00:00:00

abstract：:Between July 1985 and September 1987, 25 patients underwent 26 carotid endarterectomies based on an abnormal duplex scan (B-mode ultrasonography and pulsed-Doppler sound spectral analysis) indicative of severe stenosis or ulceration. Arteriography was not performed because of severe unstable angina requiring coronary ...

journal_title：Circulation

authors： Marshall WG Jr,Kouchoukos NT,Murphy SF,Pelate C

更新日期：1988-09-01 00:00:00

abstract：:The anatomy of 58 specimens of aortic outflow tract atresia was studied. All cases had situs solitus and levocardia, 37 had atrioventricular (AV) concordance, two had common inlet to a right ventricle and 19 had mitral atresia. The great arteries were normally interrelated in all cases. Fifty-one cases had an intact v...

journal_title：Circulation

authors： Thiene G,Gallucci V,Macartney FJ,Del Torso S,Pellegrino PA,Anderson RH

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Cell-mediated autoimmunity has been strongly implicated in the pathogenesis of viral myocarditis. METHODS AND RESULTS:Using a murine model of acute myocarditis caused by coxsackievirus B3, we analyzed the phenotypes and morphology of the infiltrating cells in the hearts by immunofluorescence and electron mi...

journal_title：Circulation

authors： Seko Y,Shinkai Y,Kawasaki A,Yagita H,Okumura K,Takaku F,Yazaki Y

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Current studies have demonstrated that applying therapeutic hypothermia for 12 to 24 hours after resuscitation from cardiac arrest improves the outcomes of cardiopulmonary resuscitation. The present study investigated whether a shorter duration of therapeutic hypothermia induced quickly and early after resus...

journal_title：Circulation

authors： Ye S,Weng Y,Sun S,Chen W,Wu X,Li Z,Weil MH,Tang W

更新日期：2012-01-03 00:00:00

abstract：:Balloon dilation angioplasty was attempted in 10 infants and children with severe congenital or operative "venous" obstructions. In five children the obstructions were "vena caval" and followed repair for transposition of the great vessels (four patients) or orthotopic liver transplantation (one patient). In the four ...

journal_title：Circulation

authors： Lock JE,Bass JL,Castaneda-Zuniga W,Fuhrman BP,Rashkind WJ,Lucas RV Jr

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:The management of asymptomatic severe mitral regurgitation remains controversial. The aim of this study was to evaluate the outcome of a watchful waiting strategy in which patients are referred to surgery when symptoms occur or when asymptomatic patients develop left ventricular (LV) enlargement, LV dysfunct...

journal_title：Circulation

authors： Rosenhek R,Rader F,Klaar U,Gabriel H,Krejc M,Kalbeck D,Schemper M,Maurer G,Baumgartner H

更新日期：2006-05-09 00:00:00