Abstract:
BACKGROUND:The goal of this study was to compare development of emotional symptomatology during smoking cessation with transdermal nicotine patches in subjects with and without a history of depression. METHODS:Twenty-five subjects, 14 with a history of depression and 11 without such a history, were evaluated before beginning of cessation, on day 8, day 30, day 90 and day 120. RESULTS AND DISCUSSION:On day 120, ten subjects have maintained abstinence: 71.4% of subjects with and 45.5% of subjects without a history of depression relapsed. Both groups presented variable emotional symptomatology and there was no significant differences between subjects with and without a past depression. On the other hand, none of the symptoms which emerged during cessation predicted the issue of cessation. However, some symptoms appearing before beginning of cessation were related to subsequent relapse: lack of pleasure seeking and tiredness. Subsequent relapsers also tended to be more tense on baseline. These early symptoms can not be considered as withdrawal symptoms, they may reflect less confidence in success. It is also suggested that development of anhedonia represents an adaptative strategy to prepare for the withdrawal suffering.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Carton S,Le Houezec J,Lagrue G,Jouvent Rdoi
10.1016/s0165-0327(01)00468-2subject
Has Abstractpub_date
2002-11-01 00:00:00pages
195-9issue
2eissn
0165-0327issn
1573-2517pii
S0165032701004682journal_volume
72pub_type
杂志文章abstract:BACKGROUND:The relationship between major depressive disorder (MDD) and dysthymia, a form of chronic depression, is complex. The two conditions are highly comorbid and it is unclear whether they are two separate disease entities. We investigated the extent to which patients with dysthymia superimposed on major depressi...
journal_title:Journal of affective disorders
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更新日期:2011-12-01 00:00:00
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journal_title:Journal of affective disorders
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journal_title:Journal of affective disorders
pub_type: 杂志文章,随机对照试验
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更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Based on the function of neuregulin 1 (NRG1) in neurodevelopment, susceptibility to bipolar disorder presumably involves this gene. The 3' region of NRG1 contains the majority of the coding exons, and transcripts from this region encode 8 of the 9 known NRG1 isoforms; therefore, this region is likely to be p...
journal_title:Journal of affective disorders
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journal_title:Journal of affective disorders
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更新日期:2010-10-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
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journal_title:Journal of affective disorders
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journal_title:Journal of affective disorders
pub_type: 杂志文章,多中心研究
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更新日期:2004-04-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
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更新日期:2003-05-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2011.03.029
更新日期:2011-08-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
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更新日期:2011-05-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2007.12.001
更新日期:2008-08-01 00:00:00
abstract::Because depression is commonly observed in the chronic fatigue syndrome (CFS), the present study sought to determine whether the symptom pattern is similar to that seen in clinically depressed subjects (DEP). Individuals with multiple sclerosis (MS) were chosen as an additional comparison group because MS is a fatigui...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(96)00015-8
更新日期:1996-06-20 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jad.2017.02.012
更新日期:2017-04-15 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2016.10.035
更新日期:2017-12-15 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.12.031
更新日期:2020-03-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.03.034
更新日期:2015-07-15 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
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更新日期:2017-02-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jad.2008.03.030
更新日期:2009-01-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.12.064
更新日期:2019-03-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
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更新日期:2021-02-15 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.09.019
更新日期:2020-01-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.12.015
更新日期:2010-09-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00190-1
更新日期:2000-12-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.04.027
更新日期:2019-06-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.07.033
更新日期:2018-12-01 00:00:00
abstract::Platelet monoamine oxidase activity (MAO) and clinical symptoms were examined in 116 individuals, 32 acute depressed patients and 84 healthy controls. The enzyme activity was lower in depressed women than controls. MAO activity correlated positively with rated clinical state in depressed women but not in depressed men...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(95)00043-m
更新日期:1995-10-09 00:00:00
abstract:INTRODUCTION:Bipolar disorder (BD) is a severe mental disorder affecting 1-4% of the population worldwide. It is characterized by periods of (hypo)manic and depressive episodes. Seasonal patterns (SP) may be observed in admission rates, mood relapses and symptom fluctuations. METHODS:We conducted a systematic review o...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2014.07.002
更新日期:2014-10-01 00:00:00