Determination of thiopurine methyltransferase genotype or phenotype optimizes initial dosing of azathioprine for the treatment of Crohn's disease.

abstract：:Gastric cytoprotection in response to different agents (prostaglandins, carotenoids, etc.) failed to occur after surgical vagotomy. Decreased gastric emptying and the increased vascular permeability were tested in ethanol-treated rats without and with bilateral surgical vagotomy. The experiments were carried out on Sp...

journal_title：Journal of clinical gastroenterology

authors： Mózsik G,Király A,Garamszegi M,Jávor T,Nagy L,Németh A,Sütö G,Vincze A

更新日期：1992-01-01 00:00:00

abstract：:The correlation of serum hepatitis C virus (HCV) titers to the progression of type C chronic liver disease remains controversial. We have investigated the relationship between serum HCV titers and different histological stages of chronic liver disease, including chronic persistent hepatitis (CPH), chronic active hepat...

journal_title：Journal of clinical gastroenterology

authors： Kao JH,Lai MY,Chen PJ,Hwang LH,Chen DS

更新日期：1996-12-01 00:00:00

abstract：GOALS:To assess the effect of unilateral versus bilateral lung transplantation (LTx) on esophageal motility and gastroesophageal reflux, and the association with the development of obstructive chronic lung allograft dysfunction (o-CLAD). BACKGROUND:We have shown that esophagogastric junction outflow obstruction, incom...

journal_title：Journal of clinical gastroenterology

authors： Tangaroonsanti A,Lee AS,Vela MF,Crowell MD,Erasmus D,Keller C,Mallea J,Alvarez F,Almansa C,DeVault KR,Houghton LA

更新日期：2019-04-01 00:00:00

abstract：GOAL:To identify patients likely to fail metronidazole as initial treatment of C. difficile infection. BACKGROUND:For moderate to severe Clostridium difficile-associated diarrhea, metronidazole is the drug of choice for treatment. Oral vancomycin is given to patients who fail metronidazole or have intolerable side eff...

journal_title：Journal of clinical gastroenterology

authors： Fernandez A,Anand G,Friedenberg F

更新日期：2004-05-01 00:00:00

abstract：:Chylous ascites remains rare as a complication of surgical intervention. Although therapeutic manoeuvres to control chylous ascites have been developed over the past 20 years, its pathophysiology is poorly understood. Conservative approaches involving dietary restriction of long-chain triglycerides and salt, together ...

journal_title：Journal of clinical gastroenterology

authors： Ohri SK,Patel T,Desa LA,Spencer J

更新日期：1990-12-01 00:00:00

abstract：:Spontaneous umbilical fistula developed in two young women with Crohn's disease. This peculiar complication of Crohn's disease has been rarely reported. In view of the complete closure of the fistulas with medical treatment, we recommended conservative medical management, at least initially, in such patients. ...

journal_title：Journal of clinical gastroenterology

authors： Veloso FT,Cardoso V,Fraga J,Carvalho J,Dias LM

更新日期：1989-04-01 00:00:00

abstract：:Constipation is not a sign but a symptom, which is not measurable scientifically. It has emotional components and must be dealt with in a holistic manner. The scientific approach aims only at the physiological derangement and serves to place the complaint in a more objective perspective. An algorithm can be constructe...

journal_title：Journal of clinical gastroenterology

authors： Devroede G

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:The prevalence of duodenal ulcer (DU) has been considered high in patients with chronic pancreatitis; however, its pathogenesis is unclear. We hypothesized that Helicobacter pylori infection plays the major pathogenetic role. STUDY:One hundred seven cases (97 men, 10 women) of chronic alcoholic pancreatitis...

journal_title：Journal of clinical gastroenterology

authors： Chebli JM,de Souza AF,Gaburri PD,Bastos KV,Ribeiro TC,Filho RJ,Chebli LA,Castro Ferreira LE

更新日期：2002-07-01 00:00:00

abstract：:Abdominal pain, excruciating and recurrent, is the dominant feature of chronic pancreatitis that initially brings most of the patients to the physician's attention. The pathogenesis of pancreatic pain is often multifactorial and explains why not all patients respond to the same mode of therapy. Increased intraductal p...

journal_title：Journal of clinical gastroenterology

authors： Pitchumoni CS

更新日期：1998-09-01 00:00:00

abstract：:Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor, originally described in adipose tissue, which controls the expression of a large number of regulatory genes in lipid metabolism and insulin sensitization. Well known by endocrinologists, thiazolidinedionesare classical PPARγ synthetic agonists...

journal_title：Journal of clinical gastroenterology

authors： Speca S,Dubuquoy L,Desreumaux P

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND AND AIM:The role of alcohol consumption in insulin resistance remains unclear. The aim of this study was to examine the association between alcohol consumption and insulin resistance in a large asymptomatic population. METHODS:A total of 2463 asymptomatic Japanese men aged 28 years or above undergoing a com...

journal_title：Journal of clinical gastroenterology

authors： Gunji T,Matsuhashi N,Sato H,Iijima K,Fujibayashi K,Okumura M,Sasabe N,Urabe A

更新日期：2011-10-01 00:00:00

abstract：GOAL:The goal of this study was to determine disparities in liver cancer surveillance among people with disabilities is the goal of this study. BACKGROUND:Using the linked administrative database in Korea, we sought to investigate (1) whether there are disparities in liver cancer surveillance according to degree and t...

journal_title：Journal of clinical gastroenterology

authors： Seo JY,Shin DW,Yu SJ,Jung JH,Han K,Cho IY,Kim SY,Choi KS,Park JH,Park JH,Kawachi I

更新日期：2020-09-04 00:00:00

abstract：BACKGROUND AND AIMS:Informed consent is a vital preprocedural step for endoscopy but there are substantial variations in its delivery. We therefore sought to assess a multifaceted intervention to improve the consent process. METHODS:Gastroenterologists at a tertiary center were educated on the recommended components o...

journal_title：Journal of clinical gastroenterology

authors： Fudman DI,Papamichael K,Roemi L,Rao V,Falchuk KR,Leffler DA,Feuerstein JD

更新日期：2019-09-01 00:00:00

abstract：GOAL:To study the rate at which Helicobacter pylori infection is treated in an immigrant cohort after diagnosis by esophagogastroduodenoscopy (EGD). BACKGROUND:Gastric cancer is the second leading cause of cancer death worldwide, and is especially prevalent in East Asia; immigrants from this part of the world remain a...

journal_title：Journal of clinical gastroenterology

authors： Cho A,Chaudhry A,Minsky-Primus L,Tso A,Perez-Perez G,Diehl DL,Marcus SG,Gany FM

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Poor preparation for elective colonoscopy is exceedingly common in persons with spinal cord injury (SCI). This unsatisfactory outcome is likely due to long-standing difficulty with evacuation and decreased colonic motility, which may result in inadequate responses to conventional bowel preparation regimens. ...

journal_title：Journal of clinical gastroenterology

authors： Korsten MA,Spungen AM,Radulovic M,Rosman AS,Hunt K,Galea MD,Kornfeld SD,Lyons BL,Yen C,Bauman WA

更新日期：2015-10-01 00:00:00

abstract：:Extrahepatic biliary atresia (EHBA), an inflammatory sclerosing cholangiopathy, is the leading indication for liver transplantation in children. The cause is still unknown, although possible infectious, genetic, and immunologic etiologies have received much recent focus. These theories are often dependent on each othe...

journal_title：Journal of clinical gastroenterology

authors： Bassett MD,Murray KF

更新日期：2008-07-01 00:00:00

abstract：:Duodenal neoplasms are a rare and not often considered cause of massive upper gastrointestinal bleeding. During a 4-year period, 859 endoscopies in patients with upper gastrointestinal bleeding revealed a duodenal tumor to be the cause of bleeding in eight patients. Three patients had a primary duodenal neoplasm, two ...

journal_title：Journal of clinical gastroenterology

authors： Sharon P,Stalnikovicz R,Rachmilewitz D

更新日期：1982-02-01 00:00:00

abstract：:Inflammatory bowel disease (IBD) commonly affects women of childbearing age, leading to concerns about the effects of the disease on fertility and pregnancy, the effect of pregnancy on the disease, and the diagnosis and treatment of IBD in the pregnancy women. The literature regarding these issues is reviewed, and a r...

journal_title：Journal of clinical gastroenterology

authors： Vender RJ,Spiro HM

更新日期：1982-06-01 00:00:00

abstract：:A 61-year-old man developed obstructive jaundice and had ultrasonographic and cholangiopancreatographic findings consistent with carcinoma of the pancreas. However, pathologically the obstruction proved to be from heterotopic pancreatic tissue compressing the common bile duct. This patient and eight previously reporte...

journal_title：Journal of clinical gastroenterology

authors： O'Reilly DJ,Craig RM,Lorenzo G,Yokoo H

更新日期：1983-04-01 00:00:00

abstract：:In two patients, treatment of amebic dysentery was followed (despite the disappearance of the infecting organism) by an illness with the clinical, pathological, and radiological characteristics of nonspecific ulcerative colitis. Their case histories indicate that in addition to persistent or recurrent amebic infection...

journal_title：Journal of clinical gastroenterology

authors： Rampton DS,Salmon PR,Clark CG

更新日期：1983-06-01 00:00:00

abstract：GOALS:The aim of this study was to compare celecoxib with loxoprofen for protection of small intestine. BACKGROUND:RCT studies report that COX-2 selective inhibitor celecoxib induces fewer small intestinal injuries than nonselective nonsteroidal anti-inflammatory drugs (NSAIDs). Loxoprofen is a prodrug nonselective NS...

journal_title：Journal of clinical gastroenterology

authors： Fujimori S,Hanada R,Hayashida M,Sakurai T,Ikushima I,Sakamoto C

更新日期：2016-03-01 00:00:00

abstract：:We compared eleven patients in whom symptoms of Crohn's disease appeared at age greater than or equal to 65 with a younger group in whom symptoms had appeared earlier. Only 64% of the older patients were initially recognized as having Crohn's disease, as compared with 96% of the younger patients even though clinical c...

journal_title：Journal of clinical gastroenterology

authors： Stalnikowicz R,Eliakim R,Diab R,Rachmilewitz D

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:Although of unproven benefit for nonalcoholic steatohepatitis (NASH), thiazolidinediones (TZDs) have emerged as a promising therapy. Little evidence exists, however, regarding sustained effects of TZDs in NASH after drug discontinuation. A recent clinical study suggests that relapse of NASH pathophysiology i...

journal_title：Journal of clinical gastroenterology

authors： Argo CK,Iezzoni JC,Al-Osaimi AM,Caldwell SH

更新日期：2009-07-01 00:00:00

abstract：:In a 6 to 12-week double-blind trial, the effect of cisapride (10 mg q.i.d.) was compared with that of placebo in 63 patients with esophagitis confirmed by endoscopy and/or biopsy. In only one patient (3%) in the cisapride group but in 43% of the placebo patients (p = 0.001), symptoms had not improved after 6 weeks. F...

journal_title：Journal of clinical gastroenterology

authors： Baldi F,Bianchi Porro G,Dobrilla G,Iascone C,Lobello R,Marzio L,Sabbatini F,Tittobello A,Verme G

更新日期：1988-12-01 00:00:00

abstract：:Two cases of Cruveilhier-Baumgarten syndrome not clinically evident and without esophageal varices in patients with liver cirrhosis and portal hypertension are presented. The diagnosis was made by real-time ultrasonography, which showed echographic caput medusae with large afferent umbilical veins and efferent inferio...

journal_title：Journal of clinical gastroenterology

authors： Caturelli E,Sperandeo G,Squillante MM,Mangia A,Gabbrielli L

更新日期：1989-06-01 00:00:00

abstract：GOALS:To determine whether the consumption of artichokes enriched with a probiotic Lactobacillus paracasei strain affects fecal microbiota composition, fecal enzyme activity, and short-chain fatty acids production and symptom profile in patients suffering from constipation. BACKGROUND:Constipation is a common gastroin...

journal_title：Journal of clinical gastroenterology

authors： Valerio F,Russo F,de Candia S,Riezzo G,Orlando A,Lonigro SL,Lavermicocca P

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Diagnosis of gastroesophageal reflux disease (GERD) based on subjective evaluation of symptoms alone is challenging. GOALS:To test the validity and reliability of a graded response questionnaire to identify patients with GERD. STUDY:Patients presenting with upper abdominal symptoms for more than a month, a...

journal_title：Journal of clinical gastroenterology

authors： Ho KY,Gwee KA,Khor JL,Selamat DS,Yeoh KG

更新日期：2008-07-01 00:00:00

abstract：:In 1992, a 61-year-old man who complained of recurrent episodes of fever and jaundice was diagnosed as having sclerosing cholangitis. In the three years that followed, the clinical picture progressively worsened; and, in 1995, the patient was hospitalized again for biliary obstruction. A liver transplantation was excl...

journal_title：Journal of clinical gastroenterology

authors： Tritto G,Iaccarino V,De Martino S,D'Agostino L

更新日期：2000-03-01 00:00:00

abstract：:Barrett's esophagus is a common premalignant condition that predisposes to the development of adenocarcinoma of the esophagus through a process of transformation from metaplasia to dysplasia and then carcinoma. Periodic endoscopic surveillance with multiple biopsies is adopted by most physicians to detect dysplasia or...

journal_title：Journal of clinical gastroenterology

authors： Hsu CW,Krevsky B,Sigman LM,Thomas RM

更新日期：1998-10-01 00:00:00

abstract：:We previously established a model of cell damage induced by an acidified medium in the rat gastric epithelial cell line RGM1. Treatment of the cells with epidermal growth factor (EGF, 1-10 ng/ml) for 4 h prevented acid-induced cell damage in a concentration-dependent manner. In contrast, basic fibroblast growth factor...

journal_title：Journal of clinical gastroenterology

authors： Furukawa O,Okabe S

更新日期：1997-01-01 00:00:00