Abstract:
OBJECTIVES:It was hypothesised that inflammation plays a dominant part in the respiratory effects of exposure to wood dust. The purpose of this study was to relate the nasal inflammatory responses of workers exposed to meranti wood dust to (a) levels of exposure, (b) respiratory symptoms and (c) respiratory function. METHODS:A cross sectional study was carried out in 1997 in a woodworking plant that used mainly meranti, among 982 workers exposed to different concentrations of wood dust. Personal sampling (n=243) of inhalable dust measurements indicated mean exposure in specific jobs, and enabled classification of 930 workers in three exposure classes (<2, 2-5, and >5 mg/m(3)) based on job title. Questionnaires were used to screen respiratory symptoms in the entire population. Lung function was measured with two different techniques, conventional flow-volume curves and the forced oscillation technique. Nasal lavage was done to assess inflammation in the upper respiratory tract. RESULTS:A negative trend between years of employment and most flow-volume variables was found in men, but not in women workers. Current exposure, however, was not related to spirometric outcomes, respiratory symptoms, or nasal cellularity. Some impedance variables were related to current exposure but also with better function at higher exposure. CONCLUSIONS:Exposure to meranti wood dust did not cause an inflammation in the upper respiratory tract nor an increase of respiratory symptoms or decrease of lung function. These data do not corroborate the hypothesis that inflammation plays a part in airway obstruction induced by wood dust.
journal_name
Occup Environ Medjournal_title
Occupational and environmental medicineauthors
Borm PJ,Jetten M,Hidayat S,van de Burgh N,Leunissen P,Kant I,Houba R,Soeprapto Hdoi
10.1136/oem.59.5.338subject
Has Abstractpub_date
2002-05-01 00:00:00pages
338-44issue
5eissn
1351-0711issn
1470-7926journal_volume
59pub_type
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journal_title:Occupational and environmental medicine
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pub_type: 杂志文章,随机对照试验
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journal_title:Occupational and environmental medicine
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journal_title:Occupational and environmental medicine
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
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更新日期:2019-03-01 00:00:00
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journal_title:Occupational and environmental medicine
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更新日期:2012-10-01 00:00:00
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pub_type: 杂志文章
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更新日期:1994-01-01 00:00:00
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journal_title:Occupational and environmental medicine
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doi:10.1136/oem.56.6.423
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journal_title:Occupational and environmental medicine
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更新日期:2004-03-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2013-101485
更新日期:2014-02-01 00:00:00
abstract:AIM:To explore attitudes to influenza immunisation and rates of uptake among staff working in acute hospitals in the UK. METHOD:A cross-sectional survey of 11,670 healthcare workers in six UK hospitals was carried out using a postal questionnaire. RESULTS:Among 6302 responders (54% of those mailed), 19% had taken up ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
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更新日期:2007-04-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章,随机对照试验
doi:10.1136/oemed-2015-103089
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVES:Few studies have examined whether exposure to chlorinated solvents is associated with multiple myeloma. We evaluated associations between multiple myeloma and occupational exposure to six chlorinated solvents: 1,1,1-trichloroethane, trichloroethylene (TCE), methylene chloride (DCM), perchloroethylene, carbon...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2009.054809
更新日期:2011-06-01 00:00:00
abstract::Fluorocarbons are widely used in industry, and manifestations of inhalation toxicity include polymer fume fever, reactive airways dysfunction, and bronchospasm. Only seven cases of alveolitis occurring acutely after inhalation have been reported. This paper presents four cases of toxic pneumonitis due to direct inhala...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.015784
更新日期:2005-06-01 00:00:00
abstract:AIMS:To examine the effect of silica exposure, in the absence of silicosis, on the prevalence of pulmonary tuberculosis (PTB), which is epidemic among South African gold miners. METHODS:Cross-sectional study of 520 gold miners over 37 years of age. Length of service, and cumulative and average dust and quartz exposure...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.018614
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVES:Compare rates of medical insurance claims for musculoskeletal disorders (MSD) between workers in a construction trade and a general worker population to determine if higher physical exposures in construction lead to higher rates of claims on personal medical insurance. METHODS:Health insurance claims betwee...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2014-102313
更新日期:2015-01-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.57.10.678
更新日期:2000-10-01 00:00:00