Abstract:
OBJECTIVE:To investigate the carcinogenicity of styrene by reanalysing data from a previous international cohort study of workers in the reinforced plastics industry. METHODS:Mortality from cancers of prior interest was analysed with more detailed consideration of exposure-response relations and an updated classification of leukaemias and lymphomas in data from a previous international cohort study of 37 021 reinforced plastics workers exposed to airborne styrene. RESULTS:Increased mortality from non-Hodgkin's lymphoma (NHL) was associated with the mean level of exposure to styrene in air (relative risk (RR) 2.31, 95% CI 1.29 to 4.12 per 100 ppm), but not with cumulative styrene exposure. Similar associations with mean exposure were observed for the oesophagus (RR 2.44, 95% CI 1.11 to 5.36 per 100 ppm) and pancreas (RR 1.89, 95% CI 1.17 to 3.09). Oesophageal cancer mortality was also associated with cumulative styrene exposure lagged 20 years (RR 1.16, 95% CI 1.03 to 1.31). No other cancer, including lung cancer, was associated with any indicator of styrene exposure. CONCLUSION:This reanalysis does not substantially change the conclusions of the original study with respect to NHL or lung cancer but new evidence concerning cancers of the oesophagus and pancreas merits further investigation.
journal_name
Occup Environ Medjournal_title
Occupational and environmental medicineauthors
Loomis D,Guha N,Kogevinas M,Fontana V,Gennaro V,Kolstad HA,McElvenny DM,Sallmén M,Saracci Rdoi
10.1136/oemed-2018-105131subject
Has Abstractpub_date
2019-03-01 00:00:00pages
157-162issue
3eissn
1351-0711issn
1470-7926pii
oemed-2018-105131journal_volume
76pub_type
杂志文章,多中心研究abstract:OBJECTIVES:The purpose of this study was to review the literature on the content of interventions focusing on return to work, employment status, or work retention in patients with cancer. Furthermore, the effect of the interventions on return to work was assessed in studies reporting return to work. METHODS:A literatu...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,评审
doi:10.1136/oem.2009.050070
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVE:To estimate the occurrence of hand eczema in hairdressers in Sweden. METHODS:The occurrence of hand eczema was estimated in a Swedish longitudinal retrospective cohort study including all female graduates from vocational schools for hairdressers from 1970 to 1995. A stratified sample from the general populat...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2005.026211
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:Occupational workload has been associated with an increased risk of osteoarthritis. The objective was to further examine the association between workload and occurrence of osteoarthritis and in particular to study whether heavy workload has similar importance as a causative factor for osteoarthritis of the hi...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
doi:10.1136/oem.2007.033365
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVE:To explore the healthy worker survivor effect (HWSE) in a study of Vermont granite workers by distinguishing "prevalent" from "incident" hires based on date of hire before or after the start of follow-up. METHODS:Records of workers between 1950 and 1982 were obtained from a medical surveillance programme. Pr...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2006.031369
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVES:To determine the mortality from non-respiratory cancers by work area among active and retired male workers of the German rubber industry. METHODS:A cohort of 11,633 male German workers was followed up for mortality from 1 January 1981 to 31 December 1991. Cohort members were active (n = 7536) or retired (n ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.55.5.325
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVES:Use of cost-benefit analysis in occupational health increases insight into the intervention strategy that maximises the cost-benefit ratio. This study presents a methodological framework identifying the most important elements of a cost-benefit analysis for occupational health settings. One of the main aims ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2011.064709
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVES:Assessment of level of exposure to platinum and platinum concentration in urine from platinum industry workers to evaluate internal exposures and excretion kinetics. METHODS:Platinum concentrations in urine samples from 34 workers were measured by adsorptive voltammetry after UV-photolysis. Morning and even...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.55.2.138
更新日期:1998-02-01 00:00:00
abstract:OBJECTIVES:To estimate the annual rates of self reported occupational asthma in different occupational groups in Sweden. METHODS:All claims of occupational asthma 1990-2 in the Swedish register of reported occupational diseases were classified according to occupation. The number of people employed in each occupational...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.53.11.757
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVES:To investigate changes in digital circulation during and after exposure to hand transmitted vibration. By studying two frequencies and two magnitudes of vibration, to investigate the extent to which haemodynamic changes depend on the vibration frequency, the vibration acceleration, and the vibration velocity...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.54.8.566
更新日期:1997-08-01 00:00:00
abstract::Crystalline silica is a widely used industrial material that is readily available worldwide, and is one of the most common types of particulate mineral pollutants. It has been classified as a group 1 human carcinogen of the respiratory system; however, whether it is linked to gastric cancer remains uncertain. We condu...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1136/oemed-2016-103552
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVES:To identify determinants of sickness absence in hospital physicians. METHODS:The Poisson regression analyses of short (1--3 days) and long (>3 days) recorded spells of sickness absence relating to potential determinants of sickness absence were based on a 2 year follow up period and cohorts of 447 (251 male...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
doi:10.1136/oem.58.6.361
更新日期:2001-06-01 00:00:00
abstract:OBJECTIVE:To report the effects of bleach use at home on the frequency of infections in 9102 school-age children participating in the HITEA project. METHODS:Parents of pupils aged 6-12 years from schools in Barcelona province (Spain), Utrecht province (the Netherlands) and Eastern and Central Finland were administered...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2014-102701
更新日期:2015-08-01 00:00:00
abstract::Aerosol sampling has evolved with changes in technology and our understanding of the importance of assessing the biologically relevant fractions of the total aerosol. During the past decade there has been international agreement on the definitions for the inhalable, thoracic, and respirable fractions and instruments h...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,评审
doi:10.1136/oem.56.11.747
更新日期:1999-11-01 00:00:00
abstract:OBJECTIVE:To assess whether CFS-like caseness (meeting the criteria for chronic fatigue syndrome (CFS)) predicts work status in the long term. METHODS:Prospective study in a sample of fatigued employees absent from work. Data were collected at baseline and four years later, and included CFS-like caseness and work stat...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2005.023176
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVES:A previous study of the short term effects of air pollution in London from April 1987 to March 1992 found associations between all cause mortality and black smoke and ozone, but no clear evidence of specificity for cardiorespiratory deaths. London data from 1992 to 1994 were analysed to examine the consisten...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.56.4.237
更新日期:1999-04-01 00:00:00
abstract:BACKGROUND:There is limited research concerning how small companies in particular, respond to health and safety messages. AIMS:To understand individuals' knowledge and beliefs about chemical risks and to compare these with those of experts. METHODS:The use of chromic acid in particular, and also other chemicals assoc...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.59.10.689
更新日期:2002-10-01 00:00:00
abstract:OBJECTIVES:To investigate the effectiveness of a counselling and education programme on work ability and work disability pension for employees in the construction industry. METHODS:Employees with a high disability risk of 38% or more in the following four years were included. Employees in the intervention group were e...
journal_title:Occupational and environmental medicine
pub_type: 临床试验,杂志文章
doi:10.1136/oem.2006.029678
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVES:To evaluate work experiences among teens enrolled in school-sponsored work (SSW) programs and compare the findings to other-working teens. This study, the first to assess work-related safety and health for teens in SSW programs, includes teens working one job and teens working multiple jobs. METHODS:A surve...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2010.059170
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:To estimate the fraction of carpal tunnel syndrome (CTS) that is attributable to work in the total adult population of the island of Montreal. METHODS:The population consisted of 1.1 million people 20-64 years of age, with 73.2% of men and 60.6% of women employed. The rates of first surgery for CTS were comp...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.54.7.519
更新日期:1997-07-01 00:00:00
abstract::: This systematic review and meta-analysis aimed to examine whether working beyond the standard working hours was associated with a greater risk of depressive disorder among workers included in published prospective studies. This manuscript was prepared according to the PRISMA guideline checklist. A database search wa...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1136/oemed-2016-103845
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVES:To describe the nationwide occurrence of work related musculoskeletal injuries among all home care service workers in Sweden, and to identify relative risks and risk factors of the injuries. METHODS:The study was based on work related injuries reported to the Swedish occupational injury information system i...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.52.10.686
更新日期:1995-10-01 00:00:00
abstract:OBJECTIVE:This study investigated the association between long-term exposure to black smoke (BS) air pollution and mortality in two related Scottish cohorts with 25 years of follow-up. METHODS:Risk factors were collected during 1970-1976 for 15331 and 6680 participants in the Renfrew/Paisley and Collaborative cohorts ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2011-100600
更新日期:2012-12-01 00:00:00
abstract:AIMS:To determine the risk of all cause mortality, cause specific mortality, and incident cancer in meatworkers. METHODS:In a retrospective cohort study, a list of members of a meatworkers union in Australia was matched with the national death and cancer registries. Standardised mortality ratios (SMR) and standardised...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.60.9.e4
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVES:To investigate the sources of high concentrations of particles of < 10 microns diameter (PM10) in classrooms, observed in a previous study on childhood exposure to PM10, and to study the correlation between classroom and outdoor concentrations of mass and elements of PM10. METHODS:Measurements of PM10 were ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.56.7.482
更新日期:1999-07-01 00:00:00
abstract:OBJECTIVES:To evaluate the effects of chronic exposure to lead on the peripheral nervous system in lead workers. METHODS:Nerve conduction velocity and electromyographic studies were performed on 31 lead workers of a battery recycling factory and 31 sex and age matched controls. 25 cases with mild distal extensor weakn...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.52.6.415
更新日期:1995-06-01 00:00:00
abstract:OBJECTIVES:Structural impairment of the renal proximal tubular epithelium induced by cadmium (Cd) was investigated by measuring the concentration of neutral endopeptidase 24.11 (NEP), an ectoenzyme of the apical brush border, in the urine of 106 male workers employed in a Cd smelter (among whom 52 were occupationally e...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.54.6.432
更新日期:1997-06-01 00:00:00
abstract:BACKGROUND:Commercial airline crew is one of the occupational groups with the highest exposures to ionising radiation. Crew members are also exposed to other physical risk factors and subject to potential disruption of circadian rhythms. METHODS:This study analyses mortality in a pooled cohort of 93 771 crew members f...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2013-101395
更新日期:2014-05-01 00:00:00
abstract:AIMS:To determine the factors that affect why some infants receive higher exposures relative to the mother's body burden than do others. METHODS:A total of 159 mother-infant pairs from a cohort of women receiving prenatal care at Magee-Womens Hospital in Pittsburgh, PA from 1992 to 1995 provided blood samples at deliv...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2003.012492
更新日期:2005-04-01 00:00:00
abstract:OBJECTIVES:To elucidate factors contributing to hard metal asthma, the entire workforce of a corporation producing hard metal tools (n = 703) was examined. METHODS:The variables evaluated were the atopy reflected by immunoglobulin E (IgE) antibody against mite allergen, history of exposure to hard metal, smoking, conc...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.53.3.188
更新日期:1996-03-01 00:00:00
abstract:INTRODUCTION:The current definition of chronic obstructive pulmonary disease (COPD) associates persistent airflow limitation and chronic respiratory symptoms. Agricultural work has been associated with an increased risk of developing COPD, but the prevalence and definition of the disease vary greatly between studies. T...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,meta分析
doi:10.1136/oemed-2018-105310
更新日期:2019-01-01 00:00:00