Abstract:
:Two alkaloids, megistoquinone I (1) and megistoquinone II (2), were isolated from the bark of Sarcomelicope megistophylla. Their structures have been elucidated on the basis of MS and NMR data. Both belong to quinoline alkaloid series and should be considered as oxidation products of a furo[2,3-b]quinoline precursor. The two alkaloids showed antibacterial properties with minimum inhibitory concentration (MIC) ranging from 2.35 to 5.25 mg/ml for 1 and 0.73 to 1.23 mg/ml for 2.
journal_name
Chem Pharm Bull (Tokyo)journal_title
Chemical & pharmaceutical bulletinauthors
Fokialakis N,Magiatis P,Chinou I,Mitaku S,Tillequin Fdoi
10.1248/cpb.50.413subject
Has Abstractpub_date
2002-03-01 00:00:00pages
413-4issue
3eissn
0009-2363issn
1347-5223journal_volume
50pub_type
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