Intrathecal baclofen: a useful agent in the treatment of well-established complex regional pain syndrome.

abstract：BACKGROUND AND OBJECTIVES:Amputations of the lower extremity remain a common procedure in a high-risk population. Perioperative morbidity and mortality reach as high as 14.1% in below-knee amputations. We aimed to determine whether regional, or neuraxial, anesthesia, when compared with general anesthesia (GA), would be...

journal_title：Regional anesthesia and pain medicine

authors： Malik O,Brovman EY,Urman RD

更新日期：2018-01-01 00:00:00

abstract：:Contemporary nonmalignant pain treatment algorithms commence with conservative non-invasive strategies, later progressing from minimally invasive interventions to invasive techniques or implantable devices. The most commonly used implantable devices are spinal cord stimulation (SCS) systems or targeted drug delivery (...

journal_title：Regional anesthesia and pain medicine

authors： Mekhail N,Mehanny DS,Armanyous S,Costandi S,Saweris Y,Azer G,Bolash R

更新日期：2020-01-12 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this study is to examine the effects of head-up tilt (70 degrees ) 30 minutes after right or left stellate ganglion block (SGB) on RR interval, QT interval, the rate-corrected QT (QTc) interval, QT dispersion (QTD), and the rate-corrected QT dispersion (QTcD) using computerized meas...

journal_title：Regional anesthesia and pain medicine

authors： Fujii K,Yamaguchi S,Egawa H,Hamaguchi S,Kitajima T,Minami J

更新日期：2004-07-01 00:00:00

abstract：:The development of chronic pain is a complex mechanism that is still not fully understood. Multiple somatic and visceral afferent pain signals, when experienced over time, cause a strengthening of certain neural circuitry through peripheral and central sensitization, resulting in the physical and emotional perceptual ...

journal_title：Regional anesthesia and pain medicine

authors： Castellanos JP,Woolley C,Bruno KA,Zeidan F,Halberstadt A,Furnish T

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:The posterior lumbar plexus block (LPB) has been used for decades to provide acute pain management after hip surgery. Unfamiliarity with the technique and its perceived difficulty, potential risks, and possible adverse effects such as quadriceps weakness have limited broader use. The quadratus lumborum blo...

journal_title：Regional anesthesia and pain medicine

authors： Polania Gutierrez JJ,Ben-David B,Rest C,Grajales MT,Khetarpal SK

更新日期：2021-02-01 00:00:00

abstract：:This article provides a brief overview of earlier work of our group on the peripheral signaling of pain, summarizes more recent studies on the role of opioids in chronic neuropathic pain, and speculates on the future of gene-based therapies as novel strategies to enhance the peripheral modulation of pain. Neurophysiol...

journal_title：Regional anesthesia and pain medicine

authors： Raja SN

更新日期：2012-03-01 00:00:00

abstract：:Abrupt cessation of intrathecal baclofen (ITB) administration can cause a life-threatening withdrawal syndrome that requires prompt diagnosis and urgent treatment. The current therapy for this condition is administration of propofol, benzodiazepines, paralytics and supportive care. This study reports a 53-year-old pat...

journal_title：Regional anesthesia and pain medicine

authors： Bellinger A,Siriwetchadarak R,Rosenquist R,Greenlee JD

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Peripheral nerve and spinal cord stimulation techniques have been used for many years. However, electrical stimulation methods rarely have been used to confirm epidural catheter placement. This study examines the practicality of this technique to confirm epidural catheter placement in obstetri...

journal_title：Regional anesthesia and pain medicine

authors： Tsui BC,Gupta S,Finucane B

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Morphine may elicit potent antinociceptive effects by binding and activating peripheral opioid receptors. However, the results in clinical studies have varied. We examined the postoperative analgesic effects of incisional morphine in patients undergoing lumpectomies and axillary node dissectio...

journal_title：Regional anesthesia and pain medicine

authors： Yarussi A,Sands R,Edge S,Lema MJ,de Leon-Casasola OA

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:It has recently been proposed that an infraclavicular brachial plexus block (BPB) at the costoclavicular (CC) space may overcome some of the limitations of the lateral sagittal (LS) approach. In this study, we hypothesized that the CC approach will produce faster onset of sensory blockade of t...

journal_title：Regional anesthesia and pain medicine

authors： Songthamwat B,Karmakar MK,Li JW,Samy W,Mok LYH

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Robotic and hand-assisted laparoscopic nephrectomies are often associated with moderate to severe postoperative pain. The aim of the current study was to investigate the analgesic efficacy of the transmuscular quadratus lumborum (TQL) block for patients undergoing robotic or hand-assisted laparoscopic nephre...

journal_title：Regional anesthesia and pain medicine

authors： Dam M,Hansen C,Poulsen TD,Azawi NH,Laier GH,Wolmarans M,Chan V,Bendtsen TF,Børglum J

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Lipid infusion reverses systemic local anesthetic toxicity. The acceptable upper limit for lipid administration is unknown and has direct bearing on clinical management. We hypothesize that high volumes of lipid could have undesirable effects and sought to identify the dose required to kill 50% of the animal...

journal_title：Regional anesthesia and pain medicine

authors： Hiller DB,Di Gregorio G,Kelly K,Ripper R,Edelman L,Boumendjel R,Drasner K,Weinberg GL

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Epidural anesthesia is a technically challenging regional anesthetic technique that can be difficult to teach to novices. Epidural simulators are now available to allow realistic training within a safe and controlled environment before attempting the procedure on patients. Potentially, this ma...

journal_title：Regional anesthesia and pain medicine

authors： Friedman Z,Siddiqui N,Katznelson R,Devito I,Bould MD,Naik V

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A sublingual sufentanil tablet is being developed as a potential alternative to intravenous (IV) opioids for the management of postoperative pain. The objective of these studies was to evaluate the pharmacokinetics, efficacy, and safety of sublingual sufentanil tablets for postoperative pain m...

journal_title：Regional anesthesia and pain medicine

authors： Minkowitz HS,Singla NK,Evashenk MA,Hwang SS,Chiang YK,Hamel LG,Palmer PP

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:Local anesthetic-induced cardiotoxicity remains a complication of regional anesthesia, with the potential to result in cardiac arrest refractory to resuscitation. Successful resuscitation using Intralipid (Baxter Pharmaceuticals by Fresenius Kabi, Uppsala, Sweden), has been reported in 2 patients with bupivac...

journal_title：Regional anesthesia and pain medicine

authors： McCutchen T,Gerancher JC

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Ultrasound-guided regional anesthesia is a rapidly growing field. There exists little information regarding the competencies involved with such a practice. The objective of this exploratory study was to characterize the behavior of novices as they undertook the challenges of learning a new tec...

journal_title：Regional anesthesia and pain medicine

authors： Sites BD,Spence BC,Gallagher JD,Wiley CW,Bertrand ML,Blike GT

更新日期：2007-03-01 00:00:00

abstract：:The progression of sensory blockade in the hand following a forearm Bier block with ropivacaine is currently unknown. The hands of 10 healthy adult human subjects were anesthetized with ropivacaine, and their sensitivities to cold and touch were tested until the completion of anesthesia. On average, insensitivity to c...

journal_title：Regional anesthesia and pain medicine

authors： Horn JL,Cordo P,Künster D,Harvey C,Cherry A,Bratt A,Gurfinkel V

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Success in performing ultrasound-guided peripheral nerve blockade (PNB) demands sound knowledge of sonoanatomy, good scanning techniques, and proper hand-eye coordination. The objectives of our study were to evaluate whether simulator training aids success of novice operators in ultrasound-gui...

journal_title：Regional anesthesia and pain medicine

authors： Niazi AU,Haldipur N,Prasad AG,Chan VW

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Neosaxitoxin (NeoSTX) is a potent site-1 sodium-channel blocker being developed as a local anesthetic. Doses of 100 μg have been used by local infiltration in anesthetized adult humans without adverse effect. We hypothesized that similar doses could cause significant respiratory, neuromuscular, and cardiovas...

journal_title：Regional anesthesia and pain medicine

authors： Wylie MC,Johnson VM,Carpino E,Mullen K,Hauser K,Nedder A,Kheir JN,Rodriguez-Navarro AJ,Zurakowski D,Berde CB

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Perineural dexamethasone or dexmedetomidine prolongs the duration of single-injection peripheral nerve block when added to the local anesthetic solution. In a randomized, controlled, double-blinded study in patients undergoing thoracoscopic pneumonectomy, we tested the hypothesis that combined...

journal_title：Regional anesthesia and pain medicine

authors： Zhang P,Liu S,Zhu J,Rao Z,Liu C

更新日期：2019-08-08 00:00:00

abstract：BACKGROUND:This prospective, randomized, observer-blinded study compared ultrasound guidance and the conventional landmark-based technique for superficial cervical plexus blockade. METHODS:Forty patients were randomly allocated to receive a block of the superficial cervical plexus using ultrasound guidance (n = 20) or...

journal_title：Regional anesthesia and pain medicine

authors： Tran DQ,Dugani S,Finlayson RJ

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Dorsal root ganglion stimulation is an emerging therapy in the treatment of chronic pain. Compared with traditional spinal cord stimulation, it allows a discretely targeted stimulation profile and may act via differing mechanisms of action. Despite these advantages, little is known about the c...

journal_title：Regional anesthesia and pain medicine

authors： Sivanesan E,Bicket MC,Cohen SP

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Anesthesiologists are increasingly utilizing the Internet for personal and professional purposes. Without guidance, the task of searching the Internet for information may be time-consuming and frustrating. This article includes a basic introduction to the Internet with suggestions and guidelin...

journal_title：Regional anesthesia and pain medicine

authors： Smith MP,Tetzlaff JE,Sheplock GJ

更新日期：1999-07-01 00:00:00

abstract：:Pain patients can be difficult. They can provoke negative feelings of frustration and anger among clinicians and damage the doctor-patient relationship. This article helps practitioners to identify those pain patients who would be prone to difficult behavior and sheds light on some of the reasons behind the behavior t...

journal_title：Regional anesthesia and pain medicine

authors： Wasan AD,Wootton J,Jamison RN

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Transversus abdominis plane (TAP) blocks have been shown to reduce postoperative pain after various abdominal surgical procedures in several studies. The motor nerves of the abdominal wall are located in the same plane as the sensory nerves affected by the TAP block. The aim of this study was ...

journal_title：Regional anesthesia and pain medicine

authors： Petersen M,Elers J,Børglum J,Belhage B,Mortensen J,Maschmann C

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Paresthesia occasionally occurs during dural puncture or injection of local anesthetic for spinal anesthesia. Although the incidence of neurologic complications after spinal anesthesia is extremely low, the significance of paresthesia is unknown. The influence of known lumbar spine pathology o...

journal_title：Regional anesthesia and pain medicine

authors： Tetzlaff JE,Dilger JA,Wu C,Smith MP,Bell G

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Cervical erector spinae plane (ESP) block has been described to anesthetize the brachial plexus (BP), however, the mechanism of its clinical effect remains unknown. As the prevertebral fascia encloses the phrenic nerves, BP and erector spinae muscles to form a prevertebral compartment, a local anesthetic inj...

journal_title：Regional anesthesia and pain medicine

authors： Elsharkawy H,Ince I,Hamadnalla H,Drake RL,Tsui BCH

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In addition to their blockade of voltage-dependent sodium channels, the action of local anesthetics at 5-hydroxytryptamine-3 (5-HT3) receptors may be clinically relevant. Because local anesthetics have different clinical properties, we have tested the hypothesis that differences in interaction...

journal_title：Regional anesthesia and pain medicine

authors： Ueta K,Suzuki T,Sugimoto M,Uchida I,Mashimo T

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Previously, we have demonstrated that extending a continuous femoral nerve block (cFNB) from overnight to 4 days after total knee arthroplasty (TKA) provides clear benefits during the infusion, but not subsequent to catheter removal. However, there were major limitations in generalizing the results of that i...

journal_title：Regional anesthesia and pain medicine

authors： Ilfeld BM,Shuster JJ,Theriaque DW,Mariano ER,Girard PJ,Loland VJ,Meyer S,Donovan JF,Pugh GA,Le LT,Sessler DI,Ball ST

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Adenosine is an endogenous compound that may have analgesic effects. Results from clinical trials are not consistent, however, and there is a need for large-scale, randomized, placebo-controlled studies to clarify the role of adenosine in the treatment of pain states, including acute nocicepti...

journal_title：Regional anesthesia and pain medicine

authors： Dirks J,Petersen KL,Rowbotham MC,Dahl JB

更新日期：2001-09-01 00:00:00