Early intralipid therapy may have prevented bupivacaine-associated cardiac arrest.

Abstract:

OBJECTIVE:Local anesthetic-induced cardiotoxicity remains a complication of regional anesthesia, with the potential to result in cardiac arrest refractory to resuscitation. Successful resuscitation using Intralipid (Baxter Pharmaceuticals by Fresenius Kabi, Uppsala, Sweden), has been reported in 2 patients with bupivacaine-induced cardiac arrest. CASE REPORT:We report another case for which Intralipid was used as part of a successful resuscitation in a patient with local anesthetic-induced cardiotoxicity. CONCLUSIONS:Early treatment with Intralipid may help prevent cardiac arrest and speed successful resuscitation efforts.

journal_name

Reg Anesth Pain Med

authors

McCutchen T,Gerancher JC

doi

10.1016/j.rapm.2007.09.006

subject

Has Abstract

pub_date

2008-03-01 00:00:00

pages

178-80

issue

2

eissn

1098-7339

issn

1532-8651

pii

S1098-7339(07)00757-2

journal_volume

33

pub_type

杂志文章
  • A translational study of the effects of ketamine and pregabalin on temporal summation of experimental pain.

    abstract:BACKGROUND AND OBJECTIVES:Central sensitization is often seen in chronic pain. A relevant and potent mechanism of central sensitization is the central integration of nociceptive impulses. Temporal summation in humans and the wind-up process in animals share common features of central integration. This preclinical and c...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/AAP.0b013e31822b0db0

    authors: Arendt-Nielsen L,Mansikka H,Staahl C,Rees H,Tan K,Smart TS,Monhemius R,Suzuki R,Drewes AM

    更新日期:2011-11-01 00:00:00

  • Is circumferential injection advantageous for ultrasound-guided popliteal sciatic nerve block?: A proof-of-concept study.

    abstract:BACKGROUND:Ultrasound (US) guidance, in some instances, can increase the success rate and reduce the onset and procedure times for peripheral nerve blockade compared with traditional nerve localization techniques. The presumptive mechanism for these benefits is the ability to accurately inject local anesthetic circumfe...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/AAP.0b013e318217a6a1

    authors: Brull R,Macfarlane AJ,Parrington SJ,Koshkin A,Chan VW

    更新日期:2011-05-01 00:00:00

  • Modulating pain in the periphery: gene-based therapies to enhance peripheral opioid analgesia: Bonica lecture, ASRA 2010.

    abstract::This article provides a brief overview of earlier work of our group on the peripheral signaling of pain, summarizes more recent studies on the role of opioids in chronic neuropathic pain, and speculates on the future of gene-based therapies as novel strategies to enhance the peripheral modulation of pain. Neurophysiol...

    journal_title:Regional anesthesia and pain medicine

    pub_type:

    doi:10.1097/AAP.0b013e31823b145f

    authors: Raja SN

    更新日期:2012-03-01 00:00:00

  • Regional to the Rescue! Axillary Brachial Plexus Nerve Block Facilitates Removal of Entrapped Transradial Catheter Placed for Cardiac Catheterization.

    abstract:OBJECTIVE:Our objective was to describe the first reported use of an axillary brachial plexus block to treat the entrapment of a transradial artery catheter due to vasospasm. CASE REPORT:A 42-year-old man undergoing transradial arterial cardiac catheterization suffered arterial vasospasm causing the catheter to become...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1097/AAP.0000000000000595

    authors: Fitzgerald BM,Babbel LA,Bacomo FK,Dhanjal ST

    更新日期:2017-07-01 00:00:00

  • Esmolol, Antinociception, and Its Potential Opioid-Sparing Role in Routine Anesthesia Care.

    abstract::β-Adrenergic blockade is an important mechanism for reducing morbidity and mortality in patients with hypertension and heart failure. Esmolol has been used widely for its chronotropic and antihypertensive effects. However, there has been recent inquiry regarding perioperative esmolol use and nociceptive modulation. Co...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章,评审

    doi:10.1097/AAP.0000000000000873

    authors: Bahr MP,Williams BA

    更新日期:2018-11-01 00:00:00

  • Clinical sonopathology for the regional anesthesiologist: part 2: bone, viscera, subcutaneous tissue, and foreign bodies.

    abstract::The use of ultrasound to facilitate regional anesthesia is an evolving area of clinical, education, and research interests. As our community's experience grows, it has become evident that anesthesiologists performing "routine" ultrasound-guided blocks may very well be confronted with atypical or even pathologic anatom...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章,评审

    doi:10.1097/AAP.0b013e3181ddd21f

    authors: Sites BD,Macfarlane AJ,Sites VR,Naraghi AM,Chan VW,Antonakakis JG,Singh M,Brull R

    更新日期:2010-05-01 00:00:00

  • Continuous versus single-injection sciatic nerve block added to continuous femoral nerve block for analgesia after total knee arthroplasty: a prospective, randomized, double-blind study.

    abstract:BACKGROUND AND OBJECTIVES:The benefit of adding sciatic nerve block (SNB) to femoral nerve block to improve analgesia after total knee arthroplasty (TKA) is uncertain. We hypothesized that the effective duration of single-injection SNB is too short to improve postoperative analgesia and that this contributes to conflic...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/AAP.0000000000000076

    authors: Sato K,Adachi T,Shirai N,Naoi N

    更新日期:2014-05-01 00:00:00

  • A paramedian approach for epidural block: an anatomic and radiologic description.

    abstract:BACKGROUND AND OBJECTIVES:Certain factors, such as intervertebral disc herniation, previous spinal surgery, and osteoarthritis may cause problems during the midline epidural procedure. The purpose of this study was to investigate the placement of the needle tip in an alternative paramedian approach in a cadaver, and ra...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1053/rapm.2003.50129

    authors: Boon JM,Prinsloo E,Raath RP

    更新日期:2003-05-01 00:00:00

  • Postoperative epidural analgesia and possible transient anterior spinal artery syndrome.

    abstract:BACKGROUND AND OBJECTIVE:We present an unusual complication of epidural analgesia used to facilitate postoperative pain relief while allowing mobilization of the patient. CASE REPORT:A 65-year-old woman with a history of chronic obstructive pulmonary disease, atherosclerotic cardiovascular disease, chronic renal failu...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1053/rapm.2001.22993

    authors: Crystal Z,Katz Y

    更新日期:2001-05-01 00:00:00

  • Mechanism of action of the erector spinae plane block: distribution of dye in a porcine model.

    abstract::This study aimed to describe the anatomical distribution of dye injected in the erector spinae plane (ESP) in a porcine living model, which could aid to reveal factors potentially relevant to the unexplained clinical effects of the ESP block. Six pigs received 0.6 mL/kg of 0.25% new methylene blue at the level of the ...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1136/rapm-2019-100964

    authors: Otero PE,Fuensalida SE,Russo PC,Verdier N,Blanco C,Portela DA

    更新日期:2020-03-01 00:00:00

  • Pain on intramuscular injection of bupivacaine, ropivacaine, with and without dexamethasone.

    abstract:BACKGROUND AND OBJECTIVES:We wished to determine which long-acting local anesthetic would produce the least pain on injection for treatment of myofascial pain disorders. We compared the pain on intramuscular injection of bupivacaine, ropivacaine, bupivacaine with dexamethasone, ropivacaine with dexamethasone, and needl...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1053/rapm.2000.8933

    authors: Krishnan SK,Benzon HT,Siddiqui T,Canlas B

    更新日期:2000-11-01 00:00:00

  • Comparison of remifentanil and propofol infusions for sedation during regional anesthesia.

    abstract:BACKGROUND AND OBJECTIVES:Patients treated with regional anesthesia often require concomitant medication for comfort and sedation. Propofol is widely used for this purpose. Remifentanil, a new ultra-short-acting opioid, exhibits at low doses distinct sedative properties that may be useful for supplementation of regiona...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s1098-7339(98)90112-2

    authors: Lauwers MH,Vanlersberghe C,Camu F

    更新日期:1998-01-01 00:00:00

  • A Double-Blind Randomized Comparison of Continuous Interscalene, Supraclavicular, and Suprascapular Blocks for Total Shoulder Arthroplasty.

    abstract:BACKGROUND AND OBJECTIVES:Continuous brachial plexus blocks at the interscalene level are associated with known diaphragm dysfunction from phrenic nerve paresis. More distal blocks along the brachial plexus may provide postsurgical analgesia while potentially having less effect on diaphragm function. Continuous intersc...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/AAP.0000000000000578

    authors: Auyong DB,Yuan SC,Choi DS,Pahang JA,Slee AE,Hanson NA

    更新日期:2017-05-01 00:00:00

  • Reconfiguring the scope and practice of regional anesthesia in a pandemic: the COVID-19 perspective.

    abstract::The COVID-19 outbreak is on the world. While many countries have imposed general lockdown, emergency services are continuing. Healthcare professionals have been infected with the virulent severe acute respiratory syndrome coronavirus-2 (SARS), which spreads by close contact and aerosols. The anesthesiologist is partic...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章,评审

    doi:10.1136/rapm-2020-101541

    authors: Ashokka B,Chakraborty A,Subramanian BJ,Karmakar MK,Chan V

    更新日期:2020-07-01 00:00:00

  • Unintentional subdural placement of epidural catheters during attempted epidural anesthesia: an anatomic study of spinal subdural compartment.

    abstract:BACKGROUND:Although infrequent, subdural block is a complication of epidural anesthesia with obvious implications. Knowledge of the spinal subdural compartment (dura-arachnoid interface) may help elucidate controversies arising from evidence that subdural catheter placement is feasible and may be difficult to identify ...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1097/AAP.0b013e31822e0e8c

    authors: Reina MA,Collier CB,Prats-Galino A,Puigdellívol-Sánchez A,Machés F,De Andrés JA

    更新日期:2011-11-01 00:00:00

  • Pectoral nerve blocks and postoperative pain outcomes after mastectomy: a meta-analysis of randomized controlled trials.

    abstract:BACKGROUND AND OBJECTIVES:Several studies have evaluated the effect of pectoral nerve blocks to improve postoperative analgesia following breast cancer surgery resulting in contradictory findings. The aim of this study was to examine the effect of Pecs blocks on postoperative analgesia in women following mastectomies. ...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1136/rapm-2019-100658

    authors: Lovett-Carter D,Kendall MC,McCormick ZL,Suh EI,Cohen AD,De Oliveira GS

    更新日期:2019-08-09 00:00:00

  • Risk Factors for and Prediction of a Difficult Neuraxial Block: A Cohort Study of 73,579 Patients from the Danish Anaesthesia Database.

    abstract:BACKGROUND:A difficult neuraxial block (DNB) may be associated with complications. The aims of this study were to estimate the prevalence of DNB, assess patient-related and organizational factors associated with DNB, and evaluate the diagnostic accuracy of an accumulated risk score for predicting DNB. METHODS:A consec...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1097/AAP.0000000000000293

    authors: Stendell L,Lundstrøm LH,Wetterslev J,Itenov TS,Rosenstock CV

    更新日期:2015-09-01 00:00:00

  • Regional anesthesia in a very low-birth-weight neonate for a neurosurgical procedure.

    abstract:BACKGROUND AND OBJECTIVES:Peripheral nerve blocks can be successfully utilized in infants for neurosurgical procedures. Our objective was utilizing a series of peripheral nerve blocks for a neurosurgical procedure in a very low-birth-weight neonate. CASE REPORT:We report the use of supraorbital, great auricular, and g...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1016/j.rapm.2003.09.008

    authors: Suresh S,Bellig G

    更新日期:2004-01-01 00:00:00

  • Calciphylaxis treated with neurolytic lumbar sympathetic block: case report and review of the literature.

    abstract:BACKGROUND AND OBJECTIVE:Calciphylaxis is a painful complication of end-stage renal disease and secondary hyperparathyroidism. Calcification most commonly affects skin and soft tissue of the lower extremities resulting in excruciatingly painful skin ulcers. Treatment involves correction of hypercalcemia and hyperphosph...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1016/s1098-7339(00)90018-x

    authors: Green JA,Green CR,Minott SD

    更新日期:2000-05-01 00:00:00

  • Posterior lumbar plexus block in children: a new anatomical landmark.

    abstract:BACKGROUND AND OBJECTIVES:Posterior lumbar plexus block is a well established anesthetic technique for lower limb surgeries. Both magnetic resonance imaging and clinical prospective studies were performed to verify if a new palpable landmark could be used for lumbar plexus block in pediatric patients. METHODS:Twenty-f...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1016/j.rapm.2007.06.395

    authors: Mello SS,Saraiva RA,Marques RS,Gasparini JR,Assis CN,Gonçalves MH

    更新日期:2007-11-01 00:00:00

  • Adherence to a Multimodal Analgesic Clinical Pathway: A Within-Group Comparison of Staged Bilateral Knee Arthroplasty Patients.

    abstract:BACKGROUND AND OBJECTIVES:Multimodal analgesic clinical pathways for joint replacement patients often include perineural catheters, but long-term adherence to these pathways has not yet been investigated. Our primary aim was to determine adherence rate to a knee arthroplasty clinical pathway for patients undergoing sta...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1097/AAP.0000000000000588

    authors: Steckelberg RC,Funck N,Kim TE,Walters TL,Lochbaum GM,Memtsoudis SG,Giori NJ,Indelli PF,Graham LJ,Mariano ER

    更新日期:2017-05-01 00:00:00

  • Acute postoperative pain is an independent predictor of chronic postsurgical pain following total knee arthroplasty at 6 months: a prospective cohort study.

    abstract:BACKGROUND:Approximately 15% of patients report persistent knee pain despite surgical success following total knee arthroplasty (TKA). The purpose of this study was to determine the association of acute-postsurgical pain (APSP) with chronic postsurgical pain (CPSP) 6 months after TKA controlling for patient, surgical a...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1136/rapm-2018-100036

    authors: Buvanendran A,Della Valle CJ,Kroin JS,Shah M,Moric M,Tuman KJ,McCarthy RJ

    更新日期:2019-02-15 00:00:00

  • Electron-microscopic imaging of endothoracic fascia in the thoracic paravertebral space in rats.

    abstract:BACKGROUND AND OBJECTIVES:Anesthesia and analgesia with paravertebral block are reportedly variable. Existence of an endothoracic fascia has been proposed as one of the possible mechanisms leading to variability. We undertook an electron-microscopy imaging study to investigate the endothoracic fascia in the thoracic pa...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1097/AAP.0b013e31824451cb

    authors: Stopar Pintaric T,Veranic P,Hadzic A,Karmakar M,Cvetko E

    更新日期:2012-03-01 00:00:00

  • Centennial of intravenous regional anesthesia. Bier's Block (1908-2008).

    abstract::The surgeon August Gustav Bier significantly influenced surgery, general medicine, and especially anesthesia. He was the father of spinal anesthesia (1898) and intravenous regional anesthesia (1908). Both anesthetic techniques are still valuable and widely applied in everyday anesthesia practices throughout the world,...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 传,历史文章,杂志文章

    doi:10.1016/j.rapm.2008.04.011

    authors: van Zundert A,Helmstädter A,Goerig M,Mortier E

    更新日期:2008-09-01 00:00:00

  • Ultrasound- or nerve stimulation-guided wrist blocks for carpal tunnel release: a randomized prospective comparative study.

    abstract:BACKGROUND AND OBJECTIVES:We hypothesized that ultrasound-guided wrist blocks may be faster to perform, and may increase success rate, compared with nerve stimulation-guided wrist blocks. METHODS:Sixty patients undergoing ambulatory endoscopic carpal tunnel release were randomly allocated to receive median and ulnar n...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.rapm.2008.01.004

    authors: Macaire P,Singelyn F,Narchi P,Paqueron X

    更新日期:2008-07-01 00:00:00

  • Median effective local anesthetic doses of plain bupivacaine and ropivacaine for spinal anesthesia administered via a spinal catheter for brachytherapy of the lower abdomen.

    abstract:BACKGROUND AND OBJECTIVES:Continuous spinal anesthesia via a spinal catheter allows adjusting the duration and extent of anesthesia to surgical needs, maintenance of hemodynamic stability, and good postoperative analgesia. This study was designed to determine the median effective local anesthetic dose of plain ropivaca...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.rapm.2007.06.396

    authors: Michalek-Sauberer A,Kozek-Langenecker SA,Heinzl H,Deusch E,Chiari A

    更新日期:2008-01-01 00:00:00

  • SIRT3 alleviates neuropathic pain by deacetylating FoxO3a in the spinal dorsal horn of diabetic model rats.

    abstract:BACKGROUND:The underlying mechanisms of neuropathic pain remain unclear. This work aimed to investigate the role of Sirtuin3 (SIRT3), an nicotinamide adenosine dinucleotide+-dependent histone deacetylase, in the development of neuropathic pain induced by type 2 diabetes mellitus (T2DM) and to explore the associated mec...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1136/rapm-2020-101918

    authors: Zhou C,Zhang Y,Jiao X,Wang G,Wang R,Wu Y

    更新日期:2021-01-01 00:00:00

  • Disappearance of wheezing during epidural lidocaine anesthesia in a patient with bronchial asthma.

    abstract:BACKGROUND AND OBJECTIVES:Local anesthetics in blood absorbed from the epidural space attenuate bronchial hyperreactivity to chemical stimuli. However, it is not documented whether local anesthetics at clinically relevant concentrations improve active wheezing in patients with bronchial asthma. CASE REPORT:We managed ...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1016/s1098-7339(99)90015-9

    authors: Shono S,Higa K,Harasawa I,Sugano H,Dan K

    更新日期:1999-09-01 00:00:00

  • Systemic Lidocaine Fails to Improve Postoperative Pain, But Reduces Time to Discharge Readiness in Patients Undergoing Laparoscopic Sterilization in Day-Case Surgery: A Double-Blind, Randomized, Placebo-Controlled Trial.

    abstract:BACKGROUND AND OBJECTIVES:Perioperative systemic lidocaine provides postoperative analgesia, decreases opioid consumption, and facilitates rehabilitation in abdominal surgery. We hypothesized that systemic lidocaine has analgesic effects in women undergoing day-case laparoscopic sterilization. METHODS:Eighty women wer...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/AAP.0000000000000398

    authors: Dewinter GB,Teunkens A,Vermeulen K,Al Tmimi L,Van de Velde M,Rex S

    更新日期:2016-05-01 00:00:00

  • Total knee arthroplasty under quadruple nerve block with ropivacaine 0.32%: effect of addition of intravenous dexmedetomidine to intravenous dexamethasone on analgesic duration.

    abstract:BACKGROUND AND OBJECTIVES:Peripheral nerve blocks reduce postoperative pain and enhance recovery after total knee arthroplasty (TKA). This study aims to assess the benefits of addition of intravenous dexmedetomidine (DexM) to intravenous dexamethasone on the analgesic duration of quadruple nerve blocks. METHODS:This d...

    journal_title:Regional anesthesia and pain medicine

    pub_type: 杂志文章

    doi:10.1136/rapm-2020-101749

    authors: Chassery C,Marty P,Rontes O,Chaubard M,Vuillaume C,Basset B,Merouani M,Marquis C,De Lussy A,Delbos MC,Casalprim J,Bataille B,Naudin C,Ferre F,Delbos A

    更新日期:2021-02-01 00:00:00