Effect of systemic adenosine on pain and secondary hyperalgesia associated with the heat/capsaicin sensitization model in healthy volunteers.

abstract：BACKGROUND:The underlying mechanisms of neuropathic pain remain unclear. This work aimed to investigate the role of Sirtuin3 (SIRT3), an nicotinamide adenosine dinucleotide+-dependent histone deacetylase, in the development of neuropathic pain induced by type 2 diabetes mellitus (T2DM) and to explore the associated mec...

journal_title：Regional anesthesia and pain medicine

authors： Zhou C,Zhang Y,Jiao X,Wang G,Wang R,Wu Y

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We present 2 case reports that illustrate that chronic intrathecal (IT) baclofen administration may be efficacious in treating patients with long-standing complex regional pain syndrome, type I (CRPS I) who have failed treatment with multiple drugs and procedures. CASE REPORTS:Both cases pres...

journal_title：Regional anesthesia and pain medicine

authors： Zuniga RE,Perera S,Abram SE

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this study is to examine the effects of head-up tilt (70 degrees ) 30 minutes after right or left stellate ganglion block (SGB) on RR interval, QT interval, the rate-corrected QT (QTc) interval, QT dispersion (QTD), and the rate-corrected QT dispersion (QTcD) using computerized meas...

journal_title：Regional anesthesia and pain medicine

authors： Fujii K,Yamaguchi S,Egawa H,Hamaguchi S,Kitajima T,Minami J

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Anesthesiologists are increasingly utilizing the Internet for personal and professional purposes. Without guidance, the task of searching the Internet for information may be time-consuming and frustrating. This article includes a basic introduction to the Internet with suggestions and guidelin...

journal_title：Regional anesthesia and pain medicine

authors： Smith MP,Tetzlaff JE,Sheplock GJ

更新日期：1999-07-01 00:00:00

abstract：:As the epidemics of obesity and diabetes expand, there are more patients with these disorders requiring elective surgery. For surgery on the extremities, peripheral nerve blocks have become a highly favorable anesthetic option when compared with general anesthesia. Peripheral blocks reduce respiratory and cardiac stre...

journal_title：Regional anesthesia and pain medicine

authors： Williams BA,Murinson BB,Grable BR,Orebaugh SL

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Continuous brachial plexus blocks at the interscalene level are associated with known diaphragm dysfunction from phrenic nerve paresis. More distal blocks along the brachial plexus may provide postsurgical analgesia while potentially having less effect on diaphragm function. Continuous intersc...

journal_title：Regional anesthesia and pain medicine

authors： Auyong DB,Yuan SC,Choi DS,Pahang JA,Slee AE,Hanson NA

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Previously, we have demonstrated that extending a continuous femoral nerve block (cFNB) from overnight to 4 days after total knee arthroplasty (TKA) provides clear benefits during the infusion, but not subsequent to catheter removal. However, there were major limitations in generalizing the results of that i...

journal_title：Regional anesthesia and pain medicine

authors： Ilfeld BM,Shuster JJ,Theriaque DW,Mariano ER,Girard PJ,Loland VJ,Meyer S,Donovan JF,Pugh GA,Le LT,Sessler DI,Ball ST

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:Local anesthetic-induced cardiotoxicity remains a complication of regional anesthesia, with the potential to result in cardiac arrest refractory to resuscitation. Successful resuscitation using Intralipid (Baxter Pharmaceuticals by Fresenius Kabi, Uppsala, Sweden), has been reported in 2 patients with bupivac...

journal_title：Regional anesthesia and pain medicine

authors： McCutchen T,Gerancher JC

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Postoperative pain is the expected but nonetheless undesirable byproduct of all surgical procedures. Humanitarian concerns and recent quasi-governmental regulations have heightened awareness about the importance of treating postoperative pain. This guideline builds upon the foundation created ...

journal_title：Regional anesthesia and pain medicine

authors： Rosenquist RW,Rosenberg J,United States Veterans Administration.

更新日期：2003-07-01 00:00:00

abstract：:Continuous peripheral nerve blockade has become a popular method of achieving postoperative analgesia for many surgical procedures. The safety and reliability of infusion pumps are dependent on their flow rate accuracy and consistency. Knowledge of pump rate profiles can help physicians determine which infusion pump i...

journal_title：Regional anesthesia and pain medicine

authors： Weisman RS,Missair A,Pham P,Gutierrez JF,Gebhard RE

更新日期：2014-09-01 00:00:00

abstract：:The American Society of Regional Anesthesia and Pain Medicine (ASRA) periodically updates its practice advisories and associated cognitive aids. The 2020 version of the ASRA Local Anesthetic Systemic Toxicity checklist was created in response to user feedback, simulation studies and advances in medical knowledge. This...

journal_title：Regional anesthesia and pain medicine

authors： Neal JM,Neal EJ,Weinberg GL

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Peripherally administered opioids, e.g., intra-articular morphine, exert their analgesic action on local opioid receptors. The present study investigated the safety and efficacy of intrabursal oxycodone and bupivacaine in comparison with bupivacaine infiltration and interscalene brachial plexu...

journal_title：Regional anesthesia and pain medicine

authors： Muittari P,Kirvelä O

更新日期：1998-09-01 00:00:00

abstract：:The use of ultrasound to facilitate regional anesthesia is an evolving area of clinical, education, and research interests. As our community's experience grows, it has become evident that anesthesiologists performing "routine" ultrasound-guided blocks may very well be confronted with atypical or even pathologic anatom...

journal_title：Regional anesthesia and pain medicine

authors： Sites BD,Macfarlane AJ,Sites VR,Naraghi AM,Chan VW,Antonakakis JG,Singh M,Brull R

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:Although complications of the epidural technique are known to affect the fetus adversely, there are no data indicating that regional analgesia directly causes harmful effects to the fetus. Our purpose was to determine the effect of epidural labor analgesia on the Doppler velocimetric indices of the uterine an...

journal_title：Regional anesthesia and pain medicine

authors： Chen LK,Yang YM,Yang YH,Lee CN,Chen SS,Sun WZ

更新日期：2011-05-01 00:00:00

abstract：INTRODUCTION:Diabetes may affect the duration of nerve block after regional anesthesia. This study aimed to compare the durations of sensory and motor block in diabetes versus non-diabetes patients after lower limb nerve block and delineate any sex-based differences in the duration of sensory and motor blocks of both d...

journal_title：Regional anesthesia and pain medicine

authors： Tang S,Wang J,Tian Y,Li X,Cui Q,Xu M,Song X,Zheng Y,Yang H,Ma C,Zhan L,Zhu C,Zhang Y,Yao M,Huang Y

更新日期：2019-07-12 00:00:00

abstract：:This article provides a brief overview of earlier work of our group on the peripheral signaling of pain, summarizes more recent studies on the role of opioids in chronic neuropathic pain, and speculates on the future of gene-based therapies as novel strategies to enhance the peripheral modulation of pain. Neurophysiol...

journal_title：Regional anesthesia and pain medicine

authors： Raja SN

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Success in performing ultrasound-guided peripheral nerve blockade (PNB) demands sound knowledge of sonoanatomy, good scanning techniques, and proper hand-eye coordination. The objectives of our study were to evaluate whether simulator training aids success of novice operators in ultrasound-gui...

journal_title：Regional anesthesia and pain medicine

authors： Niazi AU,Haldipur N,Prasad AG,Chan VW

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Sacroiliac joint injections are frequently performed procedures in the management of acute and chronic low-back pain, including patients with various immunocompromised states. Infectious complications following these procedures along with other spinal injections are rarely reported, but the true incidence is ...

journal_title：Regional anesthesia and pain medicine

authors： Nagpal G,Flaherty JP,Benzon HT

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Quadratus lumborum (QL) block is a new regional analgesic technique for upper and lower abdominal surgeries as part of a multimodal analgesic regime. It has also been reported to relieve pain after total hip arthroplasty (THA). In this prospective, randomized, double-blind study, we compared Q...

journal_title：Regional anesthesia and pain medicine

authors： Kukreja P,MacBeth L,Sturdivant A,Morgan CJ,Ghanem E,Kalagara H,Chan VWS

更新日期：2019-10-25 00:00:00

abstract：OBJECTIVE:Although uncommon, residual effects from contrast agents used more than 2 decades ago are possible. This case report is to alert clinicians to the implications of residual oil-based ionic contrast agents in the intrathecal space. CASE REPORT:A 70-year-old female with evidence of degenerative disc disease und...

journal_title：Regional anesthesia and pain medicine

authors： Navani A,Dominguez CL,Hald JK,Fishman SM

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Posterior lumbar plexus block is a well established anesthetic technique for lower limb surgeries. Both magnetic resonance imaging and clinical prospective studies were performed to verify if a new palpable landmark could be used for lumbar plexus block in pediatric patients. METHODS:Twenty-f...

journal_title：Regional anesthesia and pain medicine

authors： Mello SS,Saraiva RA,Marques RS,Gasparini JR,Assis CN,Gonçalves MH

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In order to prolong labor analgesia, one may add intrathecal epinephrine to the combination of bupivacaine and fentanyl. In this study, we tested the hypothesis that the addition of intrathecal epinephrine would lessen the requirement for a rescue dose of epidural analgesia during labor. METH...

journal_title：Regional anesthesia and pain medicine

authors： Okutomi T,Mochizuki J,Amano K,Datta S

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND/IMPORTANCE:Ultrasound (US)-guided cervical selective nerve root injections (CSNRI) have been proposed as an alternative to fluoroscopic (FL) -guided injections. When choosing US guidance, the proceduralist should be aware of potential issues confirming vertebral level, be clear regarding terminology, and up ...

journal_title：Regional anesthesia and pain medicine

authors： Ehsanian R,Schneider BJ,Kennedy DJ,Koshkin E

更新日期：2021-01-13 00:00:00

abstract：OBJECTIVE:To describe a late neurologic complication of intrathecal pump implantation and show the methods used for the diagnosis and successful treatment of transverse myelitis in this setting. CASE REPORT:A 32-year-old man with a chronic abdominal pain syndrome presented with right lower-extremity numbness 2 months ...

journal_title：Regional anesthesia and pain medicine

authors： Ubogu EE,Lindenberg JR,Werz MA

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:0.1% bupivacaine for obstetric epidural analgesia is given by infusion, using a loading dose of a higher concentration alone or in combination with opioid analgesics. A single dose of 0.1% without any additive for relief of first-stage labor pain has not yet been documented. METHODS:Fifty-eig...

journal_title：Regional anesthesia and pain medicine

authors： Christiaens F,Verborgh C,Dierick A,Camu F

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:Postdural puncture headache (PDPH) is an uncommon sequel of lumbar puncture in children. When conservative treatment with bed rest, hydration, and caffeine are ineffective, epidural blood patches are recommended and are generally effective. The purpose of this report was to highlight that when lumbar epidural...

journal_title：Regional anesthesia and pain medicine

authors： Dʼsouza G,Seidel FG,Krane EJ

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Lipid infusion reverses systemic local anesthetic toxicity. The acceptable upper limit for lipid administration is unknown and has direct bearing on clinical management. We hypothesize that high volumes of lipid could have undesirable effects and sought to identify the dose required to kill 50% of the animal...

journal_title：Regional anesthesia and pain medicine

authors： Hiller DB,Di Gregorio G,Kelly K,Ripper R,Edelman L,Boumendjel R,Drasner K,Weinberg GL

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Anesthesia and analgesia with paravertebral block are reportedly variable. Existence of an endothoracic fascia has been proposed as one of the possible mechanisms leading to variability. We undertook an electron-microscopy imaging study to investigate the endothoracic fascia in the thoracic pa...

journal_title：Regional anesthesia and pain medicine

authors： Stopar Pintaric T,Veranic P,Hadzic A,Karmakar M,Cvetko E

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The American College of Obstetricians & Gynecologists has opposed postpartum tubal ligation (PPTL) in patients whose pregnancies have been complicated by a medical condition, including hypertension. A prospective study was conducted to assess the appropriateness of spinal anesthesia for PPTL i...

journal_title：Regional anesthesia and pain medicine

authors： Suelto MD,Vincent RD Jr,Larmon JE,Norman PF,Werhan CF

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Conflicting definitions concerning the exact location of the lumbar plexus have been proposed. The present study was carried out to detect anatomical variants regarding the topographical relation between the lumbar plexus and the psoas major muscle as well as lumbar plexus anatomy at the L4-L5...

journal_title：Regional anesthesia and pain medicine

authors： Kirchmair L,Lirk P,Colvin J,Mitterschiffthaler G,Moriggl B

更新日期：2008-03-01 00:00:00