Abstract:
PURPOSE:To evaluate whether nonrecovery from acute traumatic sixth nerve palsy could be predicted from demographic factors or palsy characteristics. DESIGN:Prospective, observational case series SETTING:Multicenter (academic and private practices). OUTCOME MEASURE:Nonrecovery, defined as the presence of diplopia in primary position or more than 10 prism diopters of distance esotropia in primary position at 6 months after onset. METHODS:Using data from a previously described cohort of 84 eligible patients with acute traumatic sixth nerve palsy, we performed multivariate analyses of demographic factors and palsy characteristics. RESULTS:Nonrecovery at 6 months after onset was associated with a complete palsy (adjusted risk ratio, 9.11; 95% confidence interval [CI], 2.77-14.84) and with a bilateral palsy or paresis (adjusted risk ratio, 2.53; 95% CI, 0.98-4.29). The choice of conservative management (observation, prism, or patch) versus acute injection of Botulinum toxin (within 3 months of injury) did not influence final recovery. CONCLUSIONS:In acute traumatic sixth nerve palsy or paresis, failure to recover by 6 months after onset was associated independently with inability to abduct past midline at presentation and bilaterality. Although the overall recovery rate is high in acute traumatic sixth nerve palsy or paresis, a complete or bilateral case has a poor prognosis and is more likely to need strabismus surgery.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Holmes JM,Beck RW,Kip KE,Droste PJ,Leske DA,Pediatric Eye Disease Investigator Group.doi
10.1016/s0161-6420(01)00633-9subject
Has Abstractpub_date
2001-08-01 00:00:00pages
1457-60issue
8eissn
0161-6420issn
1549-4713pii
S0161-6420(01)00633-9journal_volume
108pub_type
杂志文章,多中心研究相关文献
OPHTHALMOLOGY文献大全abstract::Anterior optic nerve blood flow was studied in nine patients with unilateral neurogenic optic atrophy using noninvasive techniques. Disk reflectometry measurements from temporal sites demonstrated a significant reduction in the index of blood volume in atrophic optic nerves as compared with the contralateral optic ner...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(86)33671-6
更新日期:1986-06-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of astigmatic keratotomy (AK) by paired linear (transverse)-long incisions within a small optical zone in older patients with 3.00 diopters (D) or more of astigmatism who are intolerant of contact lenses, spectacles, or both. DESIGN:Prospective, noncomparative case series. PARTICIPANT...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2003.04.008
更新日期:2004-01-01 00:00:00
abstract:PURPOSE:To investigate the independent impact of the incidence and progression of diabetic retinopathy (DR) on visual functioning (VF). DESIGN:Population-based cohort study. PARTICIPANTS:A total of 518 participants aged 40 to 80 years (baseline visit 2007-2009 and second visit 6 years later, 2013-2015), with diabetes...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2018.02.011
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the accuracy of computerized videokeratography, keratometry, and the Gaussian optics formula for measuring corneal refractive power in patients after myopic laser in situ keratomileusis (LASIK). DESIGN:Noncomparative case series. PARTICIPANTS:One hundred eyes of 63 patients (mean age, 45.0 +/- 1...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(01)01001-6
更新日期:2002-04-01 00:00:00
abstract:PURPOSE:To investigate the association in Japanese between posterior vitreous attachment and the pathologies of typical age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV), 2 major forms of exudative AMD. DESIGN:Retrospective observational case series. PARTICIPANTS:A total of 378 eyes f...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.09.001
更新日期:2011-05-01 00:00:00
abstract::A 21-year-old man with known Castleman's disease, a lymphoproliferative disorder with both local and systemic manifestations, presented with decreased vision in the left eye and chromatopsia. He had infiltration of the left disc and choroid with elevation of the retina, multiple bilateral depigmented areas at the leve...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(89)32674-1
更新日期:1989-11-01 00:00:00
abstract:PURPOSE/BACKGROUND:Retinal arteriovenous malformations can be seen in a variety of ways and have multiple, associated, ocular changes that can affect vision. The authors report two cases of retinal arteriovenous malformation. In each case, a central retinal vein occlusion developed. METHODS:Each patient underwent clin...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(93)31701-x
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:To describe the heritability and sibling risk for angle closure. DESIGN:Prospective clinical study. PARTICIPANTS:Probands with primary angle closure (PAC) and primary angle-closure glaucoma (PACG) and their first-degree relatives. METHODS:One hundred probands with PAC and PACG and their first-degree relative...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.06.043
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVE:To determine the efficacy of a combination of 5-fluorouracil (5FU) and low-molecular-weight heparin (LMWH) in the treatment of unselected rhegmatogenous retinal detachment (RRD) undergoing primary vitrectomy. DESIGN:Double-masked, prospective, randomized, placebo-controlled clinical trial. PARTICIPANTS:Six ...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ophtha.2006.08.042
更新日期:2007-04-01 00:00:00
abstract:PURPOSE:To characterize retinal pigment epithelial (RPE) cell loss as evidenced by autofluorescence imaging in patients with neovascular age-related macular degeneration (AMD). DESIGN:Retrospective cohort study. PARTICIPANTS:There were 162 eyes of 116 consecutive patients with neovascular AMD examined in a retinal pr...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2012.07.076
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the safety and efficacy of transnasal orbital decompression for severe Graves' ophthalmopathy. DESIGN:Retrospective noncomparative case series with extended clinical follow-up. PARTICIPANTS:Seventy-eight consecutive subjects who were operated on for compressive optic neuropathy with loss of visu...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(00)00533-9
更新日期:2001-02-01 00:00:00
abstract::A case of preseptal cellulitis caused by Mycobacterium intracellulare is presented. A 56-year-old white woman developed erythema, induration, and tenderness of the lids of her right eye after chalazion removal, which did not respond to three weeks of broad spectrum antibiotics. Incision and drainage with biopsy reveal...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(82)34762-4
更新日期:1982-05-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of topical mitomycin-C (MMC) for treatment of postoperative residual conjunctival squamous cell carcinoma (SCC). DESIGN:Retrospective noncomparative case series. PARTICIPANTS:Five patients, two males and three females, with conjunctival and histologically proven incompletely excised c...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(01)00967-8
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVE:To characterize optic nerve head (ONH) anatomy related to the clinical optic disc margin with spectral domain-optical coherence tomography (SD-OCT). DESIGN:Cross-sectional study. PARTICIPANTS:Patients with open-angle glaucoma with focal, diffuse, and sclerotic optic disc damage, and age-matched normal contr...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2011.09.054
更新日期:2012-04-01 00:00:00
abstract::We studied the macrostructural characteristics of papillary changes of the upper tarsal conjunctiva associated with the wearing of polymethyl methacrylate (PMMA) contact lenses. Fifty subjects with elevated conjunctival papillae greater than 0.3 mm in diameter were studied. Macrostructural characteristics recorded wer...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(81)34899-4
更新日期:1981-11-01 00:00:00
abstract:PURPOSE:To identify factors predictive of remission of inflammation in new-onset anterior uveitis cases treated at tertiary uveitis care facilities. DESIGN:Retrospective cohort study. PARTICIPANTS:Patients seeking treatment at participating academic uveitis clinics within 90 days of initial diagnosis of anterior uvei...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2013.09.041
更新日期:2014-03-01 00:00:00
abstract::The authors used the Humphrey Retinal Analyzer to study the effect of acute changes in intraocular pressure (IOP) on the topography of the optic nerve head in normotensive and hypertensive eyes of cynomolgus monkeys. Chronically elevated IOP was produced monocularly in monkeys by argon laser angle treatment. In 8 hype...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(91)32345-5
更新日期:1991-01-01 00:00:00
abstract:PURPOSE:To study the associations between long-term and short-term use of topical beta-blockers and mortality. DESIGN:Prospective population-based cohort study. PARTICIPANTS:To examine long-term effects, 3842 participants aged 55 years and older were recruited. To examine short-term effects, 484 incident beta-blocker...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2008.07.004
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVE:To report the clinical and pathologic features of sarcomatous transformation of the skull with involvement of the orbit, in Paget's disease. DESIGN:Interventional case report. PARTICIPANT:An 83-year-old woman with Paget's disease who experienced progressive proptosis of the left eye. INTERVENTION:Fine-need...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(00)00180-9
更新日期:2000-08-01 00:00:00
abstract::Twelve consecutive patients with optic neuritis of unknown etiology treated with 250 to 500 mg methylprednisolone every 6 hours are described. All patients improved, some dramatically and rapidly. Patients with swollen discs and visual loss for less than 6 weeks improved uniformly, rapidly, and completely. In some pat...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(88)33220-3
更新日期:1988-01-01 00:00:00
abstract:PURPOSE:To evaluate changes in posterior corneal curvature as a possible cause of the hyperopic refractive shift observed after Descemet's stripping automated endothelial keratoplasty (DSAEK). DESIGN:Prospective, noncomparative, interventional case series. PARTICIPANTS:Thirty-four eyes of 29 patients with Fuchs' endo...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2009.04.035
更新日期:2009-09-01 00:00:00
abstract::A 35-year-old white man, on immunosuppressive medications for 3 1/2 years following a renal transplant, presented with a whitish-yellow mass at the medial end of the left lower eyelid. An initial incisional biopsy was performed that was misinterpreted as granular cell myoblastoma. The mass was subsequently excised and...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(86)33633-9
更新日期:1986-08-01 00:00:00
abstract:PURPOSE:The spaceflight-associated neuro-ocular syndrome (SANS) affects astronauts on missions to the International Space Station (ISS). The SANS has blurred vision and ocular changes as typical features. The objective of this study was to investigate if microgravity can create deformations or movements of the eye or o...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2020.07.007
更新日期:2021-02-01 00:00:00
abstract:OBJECTIVE:To investigate the impact of resident participation in cataract surgery on operative time and cost. DESIGN:Retrospective chart review. PARTICIPANTS:All patients who underwent phacoemulsification cataract surgery by an attending or resident surgeon of the Penn State Hershey Eye Center between July 1, 2004, a...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2011.06.026
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:To evaluate the clinical and histopathologic characteristics of Merkel cell carcinoma (MCC) of the eyelid. DESIGN:Retrospective case series and literature review. PARTICIPANTS:Three consecutive patients with MCC of the eyelid who were referred to the Ocular Oncology Unit of Leiden University Medical Center, N...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2007.02.024
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:To report the long-term outcomes of patients with iridocorneal endothelial (ICE) syndrome who required surgery for glaucoma. DESIGN:Retrospective, noncomparative case series. PARTICIPANTS:Twenty-six patients with ICE syndrome who underwent surgery for glaucoma at one institution between January 1987 and Janua...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(01)00725-4
更新日期:2001-10-01 00:00:00
abstract::Enucleation is the beginning of a long-term relationship between the ophthalmologist and the patient to provide a comfortable, cosmetically acceptable, anophthalmic socket. The ideal socket should have a low risk of implant extrusion, normal volume, and normal motility of the prosthesis. Aspheric motility implants pro...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(83)80054-2
更新日期:1983-09-01 00:00:00
abstract:OBJECTIVE:To determine if instrument cleaning techniques affect the rate of diffuse lamellar keratitis (DLK) after laser in situ keratomileusis (LASIK). DESIGN:Retrospective case series. PARTICIPANTS:Two hundred ten eyes of 109 patients. METHODS:A record review was performed of all patients who underwent LASIK at th...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(01)00876-4
更新日期:2002-02-01 00:00:00
abstract:PURPOSE:To ascertain the clinical features, visual outcome, and recurrence rates of ocular toxoplasmosis (OT) in a large series of patients. To determine the efficacy of various treatment strategies and identify the patients at risk of visual loss. DESIGN:Retrospective noncomparative observational case series. PARTIC...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(02)00990-9
更新日期:2002-05-01 00:00:00
abstract::Asymptomatic hyperdeviation (HD) in peripheral gaze may be caused by muscle paresis, restrictive orbital diseases, cranial neuropathy, or skew deviation. The authors suspected that this finding was often physiologic and therefore examined 61 normal subjects with the Maddox rod. Forty-seven of 61 patients (77%) showed ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(88)33108-8
更新日期:1988-06-01 00:00:00