Serum homocysteine and lipoprotein (a) concentrations in hypercholesterolemic and normocholesterolemic children.

Abstract:

:The relationship between lipids, lipoproteins, total homocysteine, and lipoprotein (a) was studied in hypercholesterolemic and normocholesterolemic children. In hypercholesterolemic children, concentrations of total cholesterol, low-density lipoprotein (LDL) cholesterol, apolipoprotein B, and triglycerides were significantly higher compared to levels in controls, whereas concentrations of high-density lipoprotein (HDL) cholesterol and apolipoprotein A-I were lower compared to those in the control group. Total serum homocysteine concentrations in children with a positive family history for cardiovascular disease CHD(+) (7.28 micromol/L) were significantly higher than those in the control group (5.45 micromol/L), and in the group of CHD(-) children (5.25 micromol/L). The median value of lipoprotein (a) in patients was 31.5 mg/dL (range, 11-209 mg/dL) and in the control group, 19 mg/dL (range, 11-95 mg/dL). Concentrations of Lp (a), exceeding 30 mg/dL, were present in 45% of CHD(+) children, in 29% of CHD(-) children, and in only 11% of the control group.

journal_name

Clin Pediatr (Phila)

journal_title

Clinical pediatrics

authors

Laskowska-Klita T,Szymczak E,Radomyska B

doi

10.1177/000992280104000304

subject

Has Abstract

pub_date

2001-03-01 00:00:00

pages

149-54

issue

3

eissn

0009-9228

issn

1938-2707

journal_volume

40

pub_type

杂志文章
  • Current attitudes regarding use of antimicrobial agents: results from physician's and parents' focus group discussions.

    abstract::Antibiotics are widely prescribed for children with nonspecific upper respiratory tract infections, contributing to the recent emergence of resistant pneumococci. To understand the reasons for the overprescription of antibiotics, we conducted focus groups with parents and with pediatricians and family physicians to as...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992289803701104

    authors: Barden LS,Dowell SF,Schwartz B,Lackey C

    更新日期:1998-11-01 00:00:00

  • Who should accept primary responsibility for the encopretic child? A successful pediatric program based on dietary control, bowel training, and family counseling.

    abstract::Such a program was used to treat 18 encopretic children; 17 improved and 14 became completely free of soiling. Most encopretic children can be managed by pediatricians and only those children with severe emotional disorders require psychiatric referral. ...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992287801700110

    authors: Hein HA,Beerends JJ

    更新日期:1978-01-01 00:00:00

  • C-Reactive Protein and Ferritin Are Associated With Organ Dysfunction and Mortality in Hospitalized Children.

    abstract::Our objective was to determine if C-reactive protein (CRP) and ferritin values alone and in combination are associated with mortality among hospitalized children. All hospitalized patients at our institution with a CRP or ferritin assay in 2015 and 2016 were included. Area under the receiver operating curves (AUROC) w...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922819837352

    authors: Horvat CM,Bell J,Kantawala S,Au AK,Clark RSB,Carcillo JA

    更新日期:2019-06-01 00:00:00

  • Congenital dislocation of the hip--diagnostic screening and treatment. A comparative study of two populations of infants and children.

    abstract::To understand why congenital dislocated hip (CDH) was diagnosed late (mean age: nine months) in children admitted to the Children's Hospital of Philadelphia (CHOP), 714 consecutive CHOP admissions, aged zero to two years, and 947 consecutive newborns delivered at the Hospital, University of Pennsylvania (HUP) were exa...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992287601500304

    authors: Kadkhoda M,Chung SM,Adebonojo FO

    更新日期:1976-03-01 00:00:00

  • Differential leukocyte count in infants of diabetic mothers. Increased band count associated with macrosomia.

    abstract::The differential leukocyte count was studied within the first 24 hours of life in 115 infants of diabetic mothers (IDMs) appropriate for gestational age (AGA), 16 IDMs large for gestational age (LGA), 104 infants of non-diabetic mothers (INM's) AGA, and 22 INMs-LGA. A significant "shift to the left" was found in IDM's...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992288602500806

    authors: Mimouni F,Porat S,Merlob P,Zaizov R,Reisner SH

    更新日期:1986-08-01 00:00:00

  • Parental compliance with after hours telephone triage advice: nurse advice service versus on-call pediatricians.

    abstract::To compare parental compliance with after-hours triage advice provided by telephone advice nurses and on-call pediatricians, a randomized controlled trial was undertaken at a university general pediatrics practice that enrolled parents or guardians calling for after-hours advice. Advice calls were randomized to a call...

    journal_title:Clinical pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1177/000992280304200707

    authors: Lee TJ,Baraff LJ,Wall SP,Guzy J,Johnson D,Woo H

    更新日期:2003-09-01 00:00:00

  • Fever of unknown origin: a diagnostic approach to this vexing problem.

    abstract::Fever is a common complaint leading families to seek medical attention. Its routine management is the bread and butter of pediatric practice. When fever is seen as prolonged beyond the expected time course (eg, 10 days for a presumed viral respiratory tract infection or 3 weeks for mononucleosis), concern for fever of...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章,评审

    doi:10.1177/0009922809347799

    authors: Tolan RW Jr

    更新日期:2010-03-01 00:00:00

  • Exploring the physically ill child's self-perceptions and the mother's perceptions of her child's needs: insights gained from the FIRO-BC--a behavior test for use with children.

    abstract::When dealing with the management of the dying patient and his family, systematic research has been very limited. Understanding the dying child's needs, as well as his family's, is important for approprirate therapy programs. The present study investigated the mother's awareness of her child's expressed and wanted need...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992287701600207

    authors: Samaniego LR,Caldwell HS,Nitschke R,Humphrey GB

    更新日期:1977-02-01 00:00:00

  • Bacteremia in patients with cystic fibrosis.

    abstract::Bacteremia in patients with cystic fibrosis (CF) has not been previously reported, a fact probably attributable to activated systemic immunity in the presence of chronic bronchopulmonary infection. We have observed two CF patients under a year of age with documented bacteremia, and a teen-aged patient with autopsy evi...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992288001901106

    authors: McCarthy MM,Rourk MH,Spock A

    更新日期:1980-11-01 00:00:00

  • The extent and patterns of multiple chronic conditions in low-income children.

    abstract:BACKGROUND AND OBJECTIVES:Little is known about the magnitude of multiple chronic conditions (MCC) in children. This study describes the prevalence of and patterns of comorbidities in children receiving Medicaid assistance. METHODS:Diagnoses from 5 years of Medicaid claims data were reviewed and identified 128,044 chi...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922815574073

    authors: Clark NM,Lachance L,Benedict MB,Little R,Leo H,Awad DF,Wilkin MK

    更新日期:2015-04-01 00:00:00

  • Development and Utility of Quality Metrics for Ambulatory Pediatric Cardiology in Kawasaki Disease.

    abstract::The Adult Congenital and Pediatric Cardiology (ACPC) Section of the American College of Cardiology sought to develop quality indicators/metrics for ambulatory pediatric cardiology practice. The objective of this study was to report the creation of metrics for patients with Kawasaki disease. Over a period of 5 months, ...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922819896098

    authors: Teitel DF,Newburger JW,Sutton N,Tani LY,Harahsheh AS,Jone PN,Mensch DJ,Cotts T,Davidson A,Dahdah N,Johnson WH Jr,Portman MA

    更新日期:2020-03-01 00:00:00

  • Prenatal counseling in heterozygotes for ornithine transcarbamylase deficiency.

    abstract::X-linked ornithine transcarbamylase deficiency (OTCD) often leads to fatal neonatal hyperammonemia in affected males (hemizygotes). In prenatal management of subsequent pregnancies, families carrying female fetuses are often reassured of the low risk of clinically overt disease. We suggest that such reassurance may be...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992289403300903

    authors: Fries MH,Kuller JA,Jurecki E,Packman S

    更新日期:1994-09-01 00:00:00

  • Incidence of serious bacterial infections in febrile children with sickle cell disease.

    abstract:OBJECTIVE:To determine the incidence of serious bacterial infections in febrile children with sickle cell disease and to describe the outcomes of children discharged from the pediatric emergency department. METHODS:We conducted a retrospective chart review of 188 febrile patients with sickle cell disease presenting to...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922813488645

    authors: Bansil NH,Kim TY,Tieu L,Barcega B

    更新日期:2013-07-01 00:00:00

  • Urban emergency department utilization by adolescents.

    abstract::This study describes urban emergency department (ED) utilization and follow-up referral patterns among adolescents. ED visits for 14-19-year-old patients at an urban university hospital with adjacent adult and pediatric emergency departments during specified months in 1993 were retrospectively reviewed. A subgroup (n=...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992280003900806

    authors: Grove DD,Lazebnik R,Petrack EM

    更新日期:2000-08-01 00:00:00

  • The magnesium load test: III. correlation of clinical and laboratory data in infants from one to six months of age.

    abstract::A study of 64 infants from one to six months of age was made using the 32-hour parenteral magnesium load test. Most of the infants were studied for neuromuscular hyperirritability or other signs compatible with magnesium deficiency; some with unrelated problems served as controls. Magnesium retention below 40 per cent...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992287501400506

    authors: Caddell JL,Byrne PA,Triska RA,McElfresh AE

    更新日期:1975-05-01 00:00:00

  • Parents view a brief violence prevention program in clinic.

    abstract::Participants were parents of 1- to 7-year-old children presenting to a pediatric clinic. The intervention was Play Nicely, 2nd edition, a multimedia educational program that teaches childhood aggression management skills. On average, parents viewed 10 to 15 min in clinic. The average age of the 89 participants was 30 ...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922807302508

    authors: Scholer SJ,Mukherjee AB,Gibbs KI,Memon S,Jongeward KL

    更新日期:2007-10-01 00:00:00

  • Mothers' perceptions of family health history and an online, parent-generated family health history tool.

    abstract::Family health history (FHH) can identify families at increased risk for disease. Purpose. To learn mothers' (1) perceptions of the benefits of FHH and (2) willingness to complete a FHH tool, My Family Health Portrait (MFHP). Methods. Qualitative in-depth interviews were conducted with mothers recruited through Cincinn...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922812467531

    authors: Berger KA,Lynch J,Prows CA,Siegel RM,Myers MF

    更新日期:2013-01-01 00:00:00

  • Clinical Factors Associated With Chest Imaging Findings in Hospitalized Infants With Bronchiolitis.

    abstract::Despite recommendations against routine imaging, chest radiography (CXR) is frequently performed on infants hospitalized for bronchiolitis. We conducted a review of 811 infants hospitalized for bronchiolitis to identify clinical factors associated with imaging findings. CXR was performed on 553 (68%) infants either on...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922817698802

    authors: Nazif JM,Taragin BH,Azzarone G,Rinke ML,Liewehr S,Choi J,Esteban-Cruciani N

    更新日期:2017-10-01 00:00:00

  • Congenital right diaphragmatic hernia. A case report and review of the literature.

    abstract::Congenital right diaphragmatic hernia can present a difficult diagnostic problem. An illustrative case is reviewed in which the diagnosis was not considered during the initial hospitalization because chest radiographs were interpreted as showing an atelectatic and pneumonic process. Once suspected, the diagnosis was m...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992288102000610

    authors: Stahl GE,Warren WS,Rosenberg H,Spackman TJ,Schnaufer L

    更新日期:1981-06-01 00:00:00

  • Throat culture is necessary after negative rapid antigen detection tests.

    abstract::This study was conducted to determine if culture confirmation is needed for a negative rapid antigen detection test. Data on 18,509 tests done in patients younger than 18 years old were reviewed. Of the 14,167 (76.5%) that were negative, 968 (6.8%) were associated with positive cultures. No significant seasonal variat...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1177/0009922806290219

    authors: Mirza A,Wludyka P,Chiu TT,Rathore MH

    更新日期:2007-04-01 00:00:00

  • Prevalence of sexually transmitted infections in at-risk adolescent females at a comprehensive, stand-alone adolescent health center in New York City.

    abstract:BACKGROUND:Sexually transmitted infections (STIs) are common among adolescents, and multiple STIs over one's lifetime can increase health risks. Few studies have assessed lifetime STI prevalence. This study evaluates minority, underserved adolescents' self-reported lifetime STI history and objective STI rates. METHODS...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922814533816

    authors: Yavorsky RL,Hollman D,Steever J,Soghomonian C,Diaz A,Strickler H,Schlecht N,Burk RD,Ochner CN

    更新日期:2014-08-01 00:00:00

  • Mobile Complex Care Plans to Enhance Parental Engagement for Children With Medical Complexity.

    abstract::Care plans can reduce care fragmentation for children with medical complexity (CMC); however, implementation is challenging. Mobile health innovations could improve implementation. This mixed methods study's objectives were to (1) evaluate feasibility of mobile complex care plans (MCCPs) for CMC enrolled in a complex ...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922818805241

    authors: Ming DY,Jackson GL,Sperling J,Gray M,Wyman Roth N,Spears T,Parente V,Bosworth H

    更新日期:2019-01-01 00:00:00

  • L-carnitine administration reduces number of episodes in cyclic vomiting syndrome.

    abstract::Patients with cyclic vomiting syndrome suffer from recurring episodes of severe nausea and vomiting. This paper presents 6 patients who responded to 1-carnitine administration. Average time between episodes was 1.7 months before carnitine administration and increased to 1.1 years after carnitine administration. Averag...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992280204100307

    authors: Van Calcar SC,Harding CO,Wolff JA

    更新日期:2002-04-01 00:00:00

  • Randomized study of six umbilical cord care regimens. Comparing length of attachment, microbial control, and satisfaction.

    abstract::Two hundred and seventy one infants were enrolled in a study to compare six different methods of treating the umbilical cord. Antimicrobial control was equal for all methods. Repeated triple dye application was considered least acceptable by staff and parents and had the longest attachment time. Povidone-iodine was as...

    journal_title:Clinical pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1177/000992288802700302

    authors: Gladstone IM,Clapper L,Thorp JW,Wright DI

    更新日期:1988-03-01 00:00:00

  • Conservative approach to the mediastinitis in childhood secondary to esophageal perforation.

    abstract::The aim of this study was to evaluate the safety and efficacy of nonoperative treatment of esophageal perforation (EP) in children. Between 1999 and 2004, 13 episodes in 12 patients were evaluated. The treatment program consisted of broad-spectrum antibiotics, nasopharyngeal aspiration, parenteral and/or enteral nutri...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992280504400204

    authors: Demirbag S,Tiryaki T,Atabek C,Surer I,Ozturk H,Cetinkursun S

    更新日期:2005-03-01 00:00:00

  • A critical review of studies of newborn discharge timing.

    abstract::The duration of hospitalization for newborns has declined dramatically, driven by efforts to control health-care costs as well as by efforts to demedicalize childbirth. In order to determine the clinical basis for this practice, the quality of the published literature on discharge timing was analyzed. Thirteen experim...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章,meta分析

    doi:10.1177/000992289503401201

    authors: Margolis LH

    更新日期:1995-12-01 00:00:00

  • Buprenorphine Overdose in Young Children: An Underappreciated Risk.

    abstract::The escalation of the opioid crisis has led to an increase in the treatment of opioid use disorder. In particular, recent legislation has allowed for office-based treatment with buprenorphine, a partial µ-opioid agonist that is believed to be safer than methadone due to a ceiling effect on respiratory depression in ad...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章,评审

    doi:10.1177/0009922819829038

    authors: Lo Re M,Chaplin M,Aronow B,Modesto-Lowe V

    更新日期:2019-06-01 00:00:00

  • Pulmonary function in older children and young adults with gastroesophageal reflux.

    abstract::A wide variety of types of pulmonary diseases and respiratory symptoms have been associated with gastroesophageal reflux (GER). Asthma, chronic bronchitis, bronchiectasis, and pulmonary fibrosis have all been linked to GER, but causal mechanisms have been difficult to establish. To characterize pulmonary function abno...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992288602501101

    authors: Allen JL,Wohl ME

    更新日期:1986-11-01 00:00:00

  • Long-term prognosis for children with nephrotic syndrome.

    abstract::Follow-up survival and health information were obtained, after a median of 27.5 years, from 132 patients who had been seen originally as children with nephrotic syndrome between 1951 and 1967. Ninety seven patients were alive. Recurring edema or proteinuria, or both, persisted in 15 percent of those still alive. Eight...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992288802700201

    authors: Wynn SR,Stickler GB,Burke EC

    更新日期:1988-02-01 00:00:00

  • Newborn screening for metabolic disorders: parental perceptions of the initial communication of results.

    abstract::Positive newborn screening (NBS) results cause significant parental distress, but little is known about how parents find out about children's screening results and what they are told. This qualitative, exploratory study reports on parents' perceptions of the initial communication of NBS results. Participants included ...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922812446011

    authors: Buchbinder M,Timmermans S

    更新日期:2012-08-01 00:00:00