Abstract:
:The escalation of the opioid crisis has led to an increase in the treatment of opioid use disorder. In particular, recent legislation has allowed for office-based treatment with buprenorphine, a partial µ-opioid agonist that is believed to be safer than methadone due to a ceiling effect on respiratory depression in adults. An increasing number of children are being exposed to buprenorphine as more adults in US households receive take-home prescriptions. The ceiling effect seen in adults does not seem to apply to young children, and intoxication with severe symptoms including fatalities can occur. This article outlines the pharmacology of buprenorphine and reviews the current literature on overdose in children. We conclude with practical recommendations for limiting potential exposure and damage to children from accidental buprenorphine overdose.
journal_name
Clin Pediatr (Phila)journal_title
Clinical pediatricsauthors
Lo Re M,Chaplin M,Aronow B,Modesto-Lowe Vdoi
10.1177/0009922819829038subject
Has Abstractpub_date
2019-06-01 00:00:00pages
613-617issue
6eissn
0009-9228issn
1938-2707journal_volume
58pub_type
杂志文章,评审abstract::Thrombocytopenia absent radius (TAR) syndrome, associated with small, echogenic kidneys and subsequent end-stage renal disease, was seen in a full-term newborn. In this infant, renal insufficiency may have increased the known risk of bleeding that is associated with TAR syndrome. Renal abnormalities and dysfunction ar...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289002900309
更新日期:1990-03-01 00:00:00
abstract::Between December 1980 and November 1984, the acute episode was studied prospectively in 187 children under 14 years presenting with acute poststreptococcal glomerulonephritis. The mean annual incidence was 19.5/10(5) children. The disease was mainly pharyngitis-associated and occurred throughout the year but peaked in...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288602500402
更新日期:1986-04-01 00:00:00
abstract::The Bronx Ongoing Pediatric Screening (BOPS) project sought to improve screening for sexual activity and sexually transmitted infections (gonorrhea and chlamydia [GCC] and HIV) in a primary care network, employing a modified learning collaborative, real-time clinical data feedback to practices, improvement coaching, a...
journal_title:Clinical pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1177/0009922817733702
更新日期:2018-07-01 00:00:00
abstract::Fifty-eight growth hormone (hGH) deficient adults who had received long-term hGH therapy and their families were contacted to assess their past and current status regarding peer relationships, educational and vocational achievements, and self-concepts. Both heterosexual and same-sex peer relationships were reported as...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288602500103
更新日期:1986-01-01 00:00:00
abstract::Obesity is a common nutritional problem among children. Using the Futrex 5000A method of bodyfat measurement, this prospective study determined the percentage bodyfat in a self-selected, indigent, predominantly black population and the accuracy of perceived body image. Bodyfat exceeded the optimal range in 39% and 67%...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289703600707
更新日期:1997-07-01 00:00:00
abstract::Congenital right diaphragmatic hernia can present a difficult diagnostic problem. An illustrative case is reviewed in which the diagnosis was not considered during the initial hospitalization because chest radiographs were interpreted as showing an atelectatic and pneumonic process. Once suspected, the diagnosis was m...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288102000610
更新日期:1981-06-01 00:00:00
abstract::Cervical adenopathy as the sole presentation of tuberculosis is seen infrequently in the pediatric age group. Despite modern treatment and public health measures, tuberculous cervical adenitis persists, and its prompt diagnosis and treatment are important from both a clinical and preventive health perspective. The aut...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288902800905
更新日期:1989-09-01 00:00:00
abstract::The utility of multicenter cognitive test methodology and resultant outcomes of supplementation with docosahexaenoic acid in healthy 4-year-old children was evaluated in a randomized, placebo-controlled, double-blind study. Subjects received 400-mg/d docosahexaenoic acid (n = 85) or matching placebo (n = 90) in capsul...
journal_title:Clinical pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/0009922807311730
更新日期:2008-05-01 00:00:00
abstract::Developmental language disorder has been reported in 3% to 10% of term infants and 30% of preterm infants (<34 weeks gestation). Screening for language delay in preterm infants can be costly and time-consuming. The objective of this study was to assess the expressive language development of preterm infants using the L...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922812439244
更新日期:2012-07-01 00:00:00
abstract::Patients with cyclic vomiting syndrome suffer from recurring episodes of severe nausea and vomiting. This paper presents 6 patients who responded to 1-carnitine administration. Average time between episodes was 1.7 months before carnitine administration and increased to 1.1 years after carnitine administration. Averag...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280204100307
更新日期:2002-04-01 00:00:00
abstract::A masked, randomized, parallel growth study was conducted in infants fed an amino acid-based formula (AF) or an extensively hydrolyzed casein-based formula (HF). Infants were enrolled between 0 and 9 days and studied to 112 days of age. Growth, formula intake, stool patterns, and serum albumin concentrations were asse...
journal_title:Clinical pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/0009922813492883
更新日期:2013-10-01 00:00:00
abstract::This study analyzed parental perception of the impact of diarrhea on quality of life of their children. A standardized questionnaire was completed by 2023 parents in Germany with children with diarrhea who were younger than 2 years old. Parents stated the most worrying aspects of diarrhea. A health score was measured ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922807310933
更新日期:2008-05-01 00:00:00
abstract::The purpose of this study was to assess the relationship between the clinical findings before starting treatment and the development quotient in children treated for congenital hypothyroidism. Patients with congenital hypothyroidism (n = 129) were divided into favorable and unfavorable groups according to intellectual...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922806289326
更新日期:2007-01-01 00:00:00
abstract::Postinfectious gastroparesis (PIGP) is a subgroup of idiopathic gastroparesis rarely reported in adolescents. This study describes 3 adolescent females with severe PIGP, who each underwent extensive workup prior to referral to a pediatric gastroenterologist. PIGP may be an underrecognized disorder in pediatrics, parti...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922811417857
更新日期:2012-02-01 00:00:00
abstract::Gynecomastia is defined as excessive development of the breast in boys. It is common in neonates and adolescents. Although in most cases this is a transient phenomenon, it might lead to significant social impediments such as decreased participation in physical education because of embarrassment. A primary care provide...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922806294800
更新日期:2007-07-01 00:00:00
abstract::Patient-centered medical home (PCMH) transformation has been challenging for pediatric practices, in part because of the National Committee for Quality Assurance (NCQA) PCMH focus on conditions and processes specific to adult patients. Realizing the potential challenges faced by pediatric practices, Vermont supported ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922816669788
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Little is known about the magnitude of multiple chronic conditions (MCC) in children. This study describes the prevalence of and patterns of comorbidities in children receiving Medicaid assistance. METHODS:Diagnoses from 5 years of Medicaid claims data were reviewed and identified 128,044 chi...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922815574073
更新日期:2015-04-01 00:00:00
abstract::Knowledge of the characteristics of family structure may be helpful to the pediatrician for predicting child abuse. During the past several decades progressive shifts from the classic family unit of two biological parents and their children to a variety of parental living arrangements have occurred. Most notable are t...
journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
doi:10.1177/000992280604500201
更新日期:2006-03-01 00:00:00
abstract::Infants with extracardiac anomalies or malformation syndromes frequently have associated cardiovascular malformations. Knowledge of these predictable patterns of associations allow rapid diagnosis and treatment of these infants. ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288402300303
更新日期:1984-03-01 00:00:00
abstract::More than 300 patients who presented consecutively to a sexual abuse clinic, a family planning clinic, and a family practice clinic filled out an anonymous survey regarding unwanted sexual experiences. In the family planning and family practice clinics, 40% of females and 16% of males reported having at least one unwa...
journal_title:Clinical pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1177/000992289503400603
更新日期:1995-06-01 00:00:00
abstract::We administered a questionnaire to determine changes in parental use and administration of over-the-counter (OTC) drugs after cyanide-laced Extra-Strength Tylenol capsules caused the deaths of at least seven people in Illinois in 1982. Three hundred area parents were studied and divided into three equally sized groups...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288402300806
更新日期:1984-08-01 00:00:00
abstract::Few studies have described the woman who chooses breast-feeding by more than simple demographics. The purpose of our study was to characterize new mothers by their infant feeding decisions, by demographic and obstetrical data, and by sources of personal support they received during their pregnancies and in making thei...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289002900105
更新日期:1990-01-01 00:00:00
abstract::This study aims to evaluate the cost-benefit of vaccination services, mostly partial series administration, provided by a mobile clinic program (MCP) in Houston for children of transient and low-income families. The study included 469 patients who visited the mobile clinics on regular service days in 2 study periods i...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922820908586
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Ethanol lock therapy (ELT) with systemic antimicrobial therapy is a promising therapy for catheter-related infection (CRI). The impact of ELT timing on treatment efficacy and costs is unknown. PROCEDURES:A prospective study was conducted in the Hematology/Oncology Unit at the Children's Hospital of Michigan...
journal_title:Clinical pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1177/0009922817717327
更新日期:2018-03-01 00:00:00
abstract::The objective was to determine the prevalence of therapies used by parents to manage acute diarrhea in their children and determine extent of parental adherence to current management guidelines and utilization of functional foods. Parents (N=623) of children with diarrhea were surveyed in a tertiary care pediatric eme...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922808327057
更新日期:2009-04-01 00:00:00
abstract::This article reports the case of a 3-year-old male with an elevated blood lead level. The child had a history of consuming imported lead-contaminated candies resulting in abdominal pains for which he was given a Hispanic folk remedy, called greta, by his mother. The home remedy aggravated the child's symptoms which pr...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922807304385
更新日期:2008-01-01 00:00:00
abstract::Propionic acidemia (PA) is one of the most frequent organic acidurias, but information on the outcome of individuals with PA is rather limited. We present data of 49 patients with PA, which were gathered from 18 metabolic centers throughout Central Europe on the occasion of an international workshop. All patients were...
journal_title:Clinical pediatrics
pub_type:
doi:10.1177/000992280404300908
更新日期:2004-11-01 00:00:00
abstract::The value of sonography in assessing chronic abdominal pain (CAP) in children, the characteristics of CAP, and the local pediatrician's practice in evaluating CAP are reported. Fifty-seven patients with CAP had abdominal and/or pelvic sonography; 56 were normal. One sonogram showed an ovarian cyst on the side opposite...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289303200304
更新日期:1993-03-01 00:00:00
abstract::To assess knowledge regarding symptoms and treatment of anaphylaxis, a vignette of a child having an allergic reaction to a peanut was presented to residents in an allergy clinic. Twelve sets of clinical outcomes ranging from severe multi-organ to mild single organ involvement were described, and residents were asked ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922820946012
更新日期:2021-01-01 00:00:00
abstract::Falszewska A, Dziechciarz P, Szajewska H. The diagnostic accuracy of Clinical Dehydration Scale in identifying dehydration in children with acute gastroenteritis: a systematic review. Clin Pediatr (Phila). 2014;53:1181-8. (Original DOI: 10.1177/0009922814538493 ). ...
journal_title:Clinical pediatrics
pub_type: 杂志文章,已发布勘误
doi:10.1177/0009922817711992
更新日期:2018-01-01 00:00:00