Ceramide-epoxides.

abstract：:(1) An analysis has been conducted of the lipids present in three obligately anaerobic bacteria isolated from the ovine rumen belonging to the genus Butyrivibrio. Two of these organisms are rich in phospholipase (A1 + A2) activity, and appear to be different strains of the species fibrisolvens. (2) The only N-containi...

journal_title：Chemistry and physics of lipids

authors： Clarke NG,Hazlewood GP,Dawson RM

更新日期：1976-10-01 00:00:00

abstract：OBJECTIVE:Fat-soluble vitamins (A, D, E and K) are isoprene derived apolar molecules. While deficiencies of these vitamins have been associated with various diseases such as type 2 diabetes and cancer, high doses of Vitamin A and D can cause toxic effects. Accurate detection of serum levels of these vitamins have criti...

journal_title：Chemistry and physics of lipids

authors： Ertugrul S,Yucel C,Sertoglu E,Ozkan Y,Ozgurtas T

更新日期：2020-08-01 00:00:00

abstract：:20-hydroxycholesterol is a signaling oxysterol with immunomodulating functions and, thus, structural analogues with reporter capabilities could be useful for studying and modulating the cellular processes concerned. We have synthesized three new 20-hydroxycholesterol-like pregn-5-en-3β-ol derivatives with fluorescent ...

journal_title：Chemistry and physics of lipids

authors： Faletrov YV,Efimova VS,Horetski MS,Tugaeva KV,Frolova NS,Lin Q,Isaeva LV,Rubtsov MA,Sluchanko NN,Novikova LA,Shkumatov VM

更新日期：2020-03-01 00:00:00

abstract：:Fusion of the single-walled liposomes of egg phosphatidylcholine as induced by the polyisoprenoids such as solanesol, trans-ethyl decaprenoate (EDP), coenzyme Q10, and dolichol has been investigated adopting the fluorescence quenching method. Relative efficiency of the polyisoprenoids employed on the induced fusion of...

journal_title：Chemistry and physics of lipids

authors： Sunamoto J,Iwamoto K,Tezuka T,Kadosaki K,Kondo H

更新日期：1983-08-01 00:00:00

abstract：:Small unilamellar vesicles (SUV) formed by egg yolk phosphatidylcholine (PC) and free oleic acid (OA) undergo aggregation induced by Ca2+ at pH greater than 7.0. The rate of the process, as monitored by turbidity changes, presents a linear dependence on phospholipid concentration and a hyperbolic dependence on Ca2+ co...

journal_title：Chemistry and physics of lipids

authors： Ortiz A,Gomez-Fernandez JC

更新日期：1988-04-01 00:00:00

abstract：:Ceramides with chemically modified polar headgroups were prepared and examined for their ability to form complex high axial ratio microstructures (CHARMS), potential drug delivery vehicles. In general, if the modified ceramide had either a hydrogen bond donor or acceptor at C-1 and C-3, including hydrophobic or hydrop...

journal_title：Chemistry and physics of lipids

authors： Goldstein AS,Gelb MH,Yager P

更新日期：2001-01-01 00:00:00

abstract：:The influence of the temperature on the adsorption of monomeric and micellar solutions of the anionic surfactant sodium dodecyl sulfate (SDS) on phosphatidylcholine (PC) liposomes was investigated using the fluorescent probe 2-(p-toluidinyl)-naphthalene-6-sodium sulfonate (TNS). The number of adsorbed molecules was qu...

journal_title：Chemistry and physics of lipids

authors： Cócera M,López O,Estelrich J,Parra JL,de la Maza A

更新日期：2003-06-01 00:00:00

abstract：:A series of long-chain methyl esters with vicinal oxo groups (1,2-diones; 1,2-diketones) were synthesized by potassium permanganate-based oxidation of methyl esters of mono-unsaturated fatty acids. The presence of two additional carbonyl groups may facilitate the synthesis of other derivatives. The starting materials ...

journal_title：Chemistry and physics of lipids

authors： Knothe G

更新日期：2002-05-01 00:00:00

abstract：:The work presented here demonstrates that the phenomenon of spontaneous vesiculation is not restricted to charged lipids and lipid mixtures, but occurs also in isoelectric phospholipid mixtures consisting of egg phosphatidylcholine (EPC) and egg lysophosphatidylcholine (lyso-EPC). 1H high-resolution NMR and freeze-fra...

journal_title：Chemistry and physics of lipids

authors： Hauser H

更新日期：1987-05-01 00:00:00

abstract：:The 3-sulfates of the S-acyl glutathione (GSH) conjugates of five natural bile acids (cholic, chenodeoxycholic, deoxycholic, ursodeoxycholic, and lithocholic) were synthesized as reference standards in order to investigate their possible formation by a rat liver cytosolic fraction. Their structures were confirmed by p...

journal_title：Chemistry and physics of lipids

authors： Mitamura K,Hori N,Mino S,Iida T,Hofmann AF,Ikegawa S

更新日期：2012-04-01 00:00:00

abstract：:Cardiolipin is a major phospholipid in mitochondria and is involved in the generation of cellular energy in the form of ATP. In mammalian and eukaryotic cells it is synthesized via the cytidine-5'-diphosphate-1,2-diacyl-sn-glycerol phosphate pathway. This brief review will describe some of the more recent studies on m...

journal_title：Chemistry and physics of lipids

authors： Mejia EM,Nguyen H,Hatch GM

更新日期：2014-04-01 00:00:00

abstract：:Fungal infections are an important cause of morbidity and pose a serious health concern especially in immunocompromised patients. Luliconazole (LUL) is a topical imidazole antifungal drug with a broad spectrum of activity. To overcome the limitations of conventional dosage forms, LUL loaded lyotropic liquid crystallin...

journal_title：Chemistry and physics of lipids

authors： Mahmood A,Rapalli VK,Waghule T,Gorantla S,Singhvi G

更新日期：2021-01-01 00:00:00

abstract：:A new acoustical method for the investigation of lipid phase transition is introduced based on the measurement of the thermal acoustic radiation (TAR) inherent in lipids. The TAR of multilamellar vesicles from dipalmitoylphosphatidylcholine (DPPC) and dimyristoylphosphatidylcholine (DMPC) was measured in the megahertz...

journal_title：Chemistry and physics of lipids

authors： Anosov AA,Barabanenkov YN,Kazanskij AS,Less YA,Sharakshane AS

更新日期：2008-06-01 00:00:00

abstract：:We investigated the effect of pegylation on the physical stability, morphology and membrane integrity of arsonoliposomes. Arsonoliposomes composed of distearoylglycerophosphocholine (DSPC), cholesterol (Chol) and the palmitoyl side chain arsonolipid (with concentrations ranging from 0 mol% [DSPC/Chol vesicles] to 53 m...

journal_title：Chemistry and physics of lipids

authors： Piperoudi S,Fatouros D,Ioannou PV,Frederik P,Antimisiaris SG

更新日期：2006-02-01 00:00:00

abstract：:The gel-like liquid phase transition of dimyristoylphosphatidylcholine (DMPC) large unilamellar vesicles prepared by reverse phase evaporation has been investigated in buffers containing ethanol by quasi-elastic light scattering (QLS) and vibrational (infrared and Raman) spectroscopy. With the QLS technique, the relat...

journal_title：Chemistry and physics of lipids

authors： Hantz E,Cao A,Taillandier E

更新日期：1988-12-01 00:00:00

abstract：:The role of membrane cholesterol as a crucial regulator in the structure and function of membrane proteins and receptors is well documented. However, there is a lack of consensus on the mechanism for such regulation. We have previously shown that the function of an important neuronal receptor, the serotonin1A receptor...

journal_title：Chemistry and physics of lipids

authors： Pal S,Chakraborty H,Bandari S,Yahioglu G,Suhling K,Chattopadhyay A

更新日期：2016-03-01 00:00:00

abstract：:Under condition of ROS formation in lipid membranes, free radical reactions can proceed in both hydrophobic (peroxidation of lipids, POL) and polar (free radical fragmentation) parts of the bilayer. Free-radical fragmentation is typical for the lipids containing a hydroxyl group in β-position with respect to an ester ...

journal_title：Chemistry and physics of lipids

authors： Olshyk VN,Melsitova IV,Yurkova IL

更新日期：2014-01-01 00:00:00

abstract：:In liotropic lipid systems phase transitions can be induced isothermally by changing the solvent concentration or composition; alternatively, lipid composition can be modified by (bio)chemical means. The probability for isothermal phase transitions increases with the decreasing transition entropy; it is proportional t...

journal_title：Chemistry and physics of lipids

authors： Cevc G

更新日期：1991-03-01 00:00:00

abstract：:Cardiolipins (CLs) are ancient and unusual dimeric phospholipids localized in the plasma membrane of bacteria and in the inner mitochondrial membrane of eukaryotes. In mitochondria, two types of asymmetries--trans-membrane and molecular--are essential determinants of CL functions. In this review, we describe CL-based ...

journal_title：Chemistry and physics of lipids

authors： Kagan VE,Chu CT,Tyurina YY,Cheikhi A,Bayir H

更新日期：2014-04-01 00:00:00

abstract：:Low density lipoprotein (LDL) cholesterol is known to be oxidized both in vitro and in vivo giving rise to oxygenated sterols. Conflicting results, however, have been reported concerning both the nature and the relative concentrations of these compounds in oxidized human LDL. We examined the extracts obtained from Cu(...

journal_title：Chemistry and physics of lipids

authors： Malavasi B,Rasetti MF,Roma P,Fogliatto R,Allevi P,Catapano AL,Galli G

更新日期：1992-10-01 00:00:00

abstract：:Fourier Transform Infra-red and Raman Spectroscopies indicate that 7 alpha-hydroxycholesterol and 7-ketocholesterol have a diminished capacity to condense (increase the packing order of) fluid-state dipalmitoylphosphatidylcholine (DPPC) acyl chains when compared with the effects of cholesterol and the other oxidized s...

journal_title：Chemistry and physics of lipids

authors： Rooney M,Tamura-Lis W,Lis LJ,Yachnin S,Kucuk O,Kauffman JW

更新日期：1986-08-01 00:00:00

abstract：:Trehalose lipids are bacterial biosurfactants which present interesting physicochemical and biological properties. These glycolipids have a number of different commercial applications and there is an increasing interest in their use as therapeutic agents. The amphiphilic nature of trehalose lipids points to the membra...

journal_title：Chemistry and physics of lipids

authors： Teruel JA,Ortiz A,Aranda FJ

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:In this study, we aimed to compare the serum lipid profile and fatty acid (FA) compositions of erythrocyte membrane (EM) and plasma in three different patient groups (group 1: type 2 diabetes mellitus (T2DM)+end-stage renal disease (ESRD), group 2: ESRD, group 4: T2DM) and healthy controls (group 3) simultan...

journal_title：Chemistry and physics of lipids

authors： Sertoglu E,Kurt I,Tapan S,Uyanik M,Serdar MA,Kayadibi H,El-Fawaeir S

更新日期：2014-02-01 00:00:00

abstract：:To exploit the potential of Didodecyldimethylammonium bromide (D12DAB) as a core lipidic constituent, an attempt was made to fabricate and optimize cationic nanostructured lipid carriers (cNLCs) using a cost-effective microemulsification methodology. Designed composition was optimized by studying the effect of differe...

journal_title：Chemistry and physics of lipids

authors： Kanwar R,Kaur G,Mehta SK

更新日期：2016-03-01 00:00:00

abstract：:Based on size and compositional data, models for the two major density subclasses of human serum high density lipoproteins have been developed. Descriptions of both the surface structure of the high density lipoproteins and the structure of their apolar core regions are integral parts of these models. The surface is d...

journal_title：Chemistry and physics of lipids

authors： Verdery RB,Nichols AV

更新日期：1975-04-01 00:00:00

abstract：:The interaction of monovalent cations and membrane phospholipids has a great theoretical and practical importance. Because of the very low differences between the binding forces of monovalent cations to phospholipids, the methods applied up till now did not succeed in completely elucidating this interaction. We develo...

journal_title：Chemistry and physics of lipids

authors： Cserháti T,Szögyi M

更新日期：1983-12-01 00:00:00

abstract：:The aim of this study was to develop, optimize and evaluate the potential of solid lipid nanoparticles (SLNs) as a topical delivery system for targeted and prolonged release of Fluocinolone acetonide (FA). FA loaded SLNs were successfully developed by an emulsification-ultrasonication method and optimized using 17-run...

journal_title：Chemistry and physics of lipids

authors： Pradhan M,Singh D,Singh MR

更新日期：2015-02-01 00:00:00

abstract：:X-ray diffraction data taken at high instrumental resolution were obtained for EPC and DMPC under various osmotic pressures, primarily at T = 30 degrees C. The headgroup thickness DHH was obtained from relative electron density profiles. By using volumetric results and by comparing to gel phase DPPC we obtain areas AE...

journal_title：Chemistry and physics of lipids

authors： Petrache HI,Tristram-Nagle S,Nagle JF

更新日期：1998-09-01 00:00:00

abstract：:Interactions of the peptides melittin and magainin with phospholipid vesicle membranes have been studied using fluorescence correlation spectroscopy. Molecular interactions of melittin and magainin with phospholipid membranes are performed in rhodamine-entrapped vesicles (REV) and in rhodamine-labelled phospholipid ve...

journal_title：Chemistry and physics of lipids

authors： Pramanik A,Thyberg P,Rigler R

更新日期：2000-01-01 00:00:00

abstract：:Human erythrocyte band 3 reconstituted into phospholipid vesicles has been used for studying the interaction of interdigitated lipid bilayer with an integral membrane protein. The interdigitated gel phase in DPPG/band 3 or DPPG/DMPC/band 3 systems was induced with polymyxin B (PMB) or Tris+. The phase transitions of t...

journal_title：Chemistry and physics of lipids

authors： Wang PY,Lu JZ,Chen JW,Hwang F

更新日期：1994-03-01 00:00:00