Arrangement of lipid and protein in human serum high density lipoproteins: a proposed model.

abstract：:A simplified procedure for lipid digestion, well suited for handling a large number of samples, was used to analyze a variety of common phospholipids. This procedure involves digestion of phospholipids in perchloric acid at 130 degrees C with minimal sample manipulation. For all lipids tested, complete destruction, ne...

journal_title：Chemistry and physics of lipids

authors： Mrsny RJ,Volwerk JJ,Griffith OH

更新日期：1986-01-01 00:00:00

abstract：:The work reported herein deals with the synthesis and the aggregation behavior studies of synthetic lipids bearing a non-ionic polar head made up of a tris(hydroxymethyl) aminomethane (tris) moiety linked with an aminoglycerol interface. The hydrophobic chains with variable lengths were grafted onto the hydroxyl funct...

journal_title：Chemistry and physics of lipids

authors： Polidori A,Michel N,Fabiano AS,Pucci B

更新日期：2005-07-01 00:00:00

abstract：:Age-related fluorescent and cross-linked proteins increase with lipid oxidation of tissues. The fluorophores and cross-links have been considered to be conjugated Schiff bases between amino groups of proteins and malonaldehyde. Our recent studies showed that the fluorophores produced in the in vitro reaction of protei...

journal_title：Chemistry and physics of lipids

authors： Kikugawa K,Beppu M

更新日期：1987-07-01 00:00:00

abstract：:The 13C- and 31P-NMR spectra and DSC thermograms of unsonicated dispersions consisting of phospholipids of varying methylation stages of the propanolamine head group were investigated. Methylation of the head group was accompanied by a corresponding reduction in the phase transition temperatures. In the liquid crystal...

journal_title：Chemistry and physics of lipids

authors： Gawrisch K,Arnold K,Rüger HJ,Kertscher P,Nuhn P

更新日期：1977-12-01 00:00:00

abstract：:Mycobacteria are intracellular pathogens that can invade and survive within host macrophages. Mycobacterial infections remain a major cause of mortality and morbidity worldwide, with serious concerns of emergence of multi and extensively drug-resistant tuberculosis. While significant advances have been made in identif...

journal_title：Chemistry and physics of lipids

authors： Viswanathan G,Jafurulla M,Kumar GA,Raghunand TR,Chattopadhyay A

更新日期：2018-07-01 00:00:00

abstract：:Low density lipoprotein (LDL) cholesterol is known to be oxidized both in vitro and in vivo giving rise to oxygenated sterols. Conflicting results, however, have been reported concerning both the nature and the relative concentrations of these compounds in oxidized human LDL. We examined the extracts obtained from Cu(...

journal_title：Chemistry and physics of lipids

authors： Malavasi B,Rasetti MF,Roma P,Fogliatto R,Allevi P,Catapano AL,Galli G

更新日期：1992-10-01 00:00:00

abstract：:Plasmalogens (1-O-1'-alkenyl-2-acylglycerophospholipids) and to a lesser extent the 1-O-alkyl analogs are ubiquitous and in some cases major constituents of mammalian cellular membranes and of anaerobic bacteria. In archaebacteria polar lipids of the cell envelope are either diphytanylglycerolipids or bipolar macrocyc...

journal_title：Chemistry and physics of lipids

authors： Paltauf F

更新日期：1994-12-01 00:00:00

abstract：:The properties of dipalmitoylphosphatidylcholine (DPPC):6-ketocholestanol bilayer at 50 mol% sterol were studied using the molecular dynamics simulation technique. Our simulations were performed at constant pressure and temperature on a nanosecond time scale. Data from this simulation were compared to the results of o...

journal_title：Chemistry and physics of lipids

authors： Smondyrev AM,Berkowitz ML

更新日期：2001-07-01 00:00:00

abstract：:Phosphatidylserine (PS) is an aminophospholipid that is prone to glycation. In oxidative conditions, glycated PS may lead to the formation of Amadori compounds and advanced glycated end products (AGEs), which are known to accumulate in diabetic patients. Nevertheless, there have been no studies that identified product...

journal_title：Chemistry and physics of lipids

authors： Maciel E,da Silva RN,Simões C,Melo T,Ferreira R,Domingues P,Domingues MR

更新日期：2013-09-01 00:00:00

abstract：:The indolic plant hormone, indole-3-acetic acid (IAA), mediated the transport of Mn2+ and other ions into small unilamellar vesicles prepared from soybean phosphatidylinositol (PI) and this process has been studied using 31P nuclear magnetic resonance spectroscopy (NMR). The rate of Mn2+ movement into PI vesicles is d...

journal_title：Chemistry and physics of lipids

authors： Jones GP,Misso NL,Paleg LG

更新日期：1992-04-01 00:00:00

abstract：:The application of fluorescence methodologies to obtain information about the extent, dynamics and topology of peptide interaction with binary phospholipid (mainly zwitterionic/anionic) mixtures is reviewed. First, general approaches based on peptide (tryptophan residues) fluorescence properties that give information ...

journal_title：Chemistry and physics of lipids

authors： Loura LM,de Almeida RF,Coutinho A,Prieto M

更新日期：2003-01-01 00:00:00

abstract：:The effect of several synthetic peptides based on the sequence of human pulmonary surfactant-associated protein B (SPB) on the molecular packing of model membrane lipids (7:1 dipalmitoyl phosphatidylcholine (DPPC)/dipalmitoyl phosphatidylglycerol (DPPG)) was studied using fluorescence anisotropy. This information was ...

journal_title：Chemistry and physics of lipids

authors： Baatz JE,Sarin V,Absolom DR,Baxter C,Whitsett JA

更新日期：1991-12-01 00:00:00

abstract：:Various optically active hydroxy derivatives of polyunsaturated fatty acids were easily oxidised to their corresponding keto derivatives using Dess-Martin periodinane. The reaction was run on the millimolar scale with good yields and without appreciable isomerisation of the surrounding double bonds. Reduction of these...

journal_title：Chemistry and physics of lipids

authors： Iacazio G

更新日期：2003-10-01 00:00:00

abstract：:Recent studies have revealed that sphingomyelin (SM) is involved in metabolic syndrome and is a new target of an anti-metabolic syndrome drug. Deficiencies in the enzyme SM synthase 1 (SMS1) result in severe abnormalities, whereas deficiencies in SMS2 do not. SMS1 and SMS2 synthesize SM under similar conditions, so th...

journal_title：Chemistry and physics of lipids

authors： Zama K,Mitsutake S,Watanabe K,Okazaki T,Igarashi Y

更新日期：2012-10-01 00:00:00

abstract：:In the present work, we report the physico-chemical properties and structural characteristics of special polyhydroxy fatty acid nanoparticles after their fusion by means of attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR), X-ray diffraction (XRD), differential scanning calorimetry (DSC), ...

journal_title：Chemistry and physics of lipids

authors： Heredia-Guerrero JA,Domínguez E,Luna M,Benítez JJ,Heredia A

更新日期：2010-03-01 00:00:00

abstract：:For the design of new synthetic substrates for the assay of pancreatic lipases activity, acyl dialkylglycerols of variable chain length were prepared. Titrimetric assay of these substrates showed the highest lipolytic activity of porcine pancreas lipase (pPL) with butanoyl dibutylglycerol. The activity is lower but co...

journal_title：Chemistry and physics of lipids

authors： Ciuffreda P,Loseto A,Manzocchi A,Santaniello E

更新日期：2001-06-01 00:00:00

abstract：:Ceriporiopsis subvermispora is a selective white-rot fungus that secretes alk(en)ylitaconic acids named ceriporic acids, known as ion redox silencers. In this study, we analysed a series of extracellular lipid-related metabolites produced by the fungus and found that a wide variety of ceriporic acids and fatty acids, ...

journal_title：Chemistry and physics of lipids

authors： Nishimura H,Murayama K,Watanabe T,Honda Y,Watanabe T

更新日期：2012-01-01 00:00:00

abstract：:The recently discovered marine fatty acid (+/-)-2-methoxy-13-methyltetradecanoic acid was synthesized for the first time in six steps (26% overall yield) starting from commercially available methyl 12-methyltridecanoate. The synthetic approach provided enough material to corroborate the structure of the acid, which wa...

journal_title：Chemistry and physics of lipids

authors： Carballeira NM,Cruz H,Orellano EA,González FA

更新日期：2003-12-01 00:00:00

abstract：:The interactions of iodine, iodide and triiodide with phosphatidylcholine multilayers have been investigated in order to find supporting data for conduction mechanisms of iodine-doped bimolecular lipid membranes. On the basis of order-disorder parameters it can be concluded that phospholipid multilayers interact with ...

journal_title：Chemistry and physics of lipids

authors： Loshchilova E,Karvaly B

更新日期：1977-06-01 00:00:00

abstract：:Cannabinoid receptor agonists diminish responses to painful stimuli. Extensive evidence demonstrates that CB(1) cannabinoid receptor activation inhibits pain responses. Recently, the synthesis of CB(2) cannabinoid receptor-selective agonists has allowed testing whether CB(2) receptor activation inhibits pain. CB(2) re...

journal_title：Chemistry and physics of lipids

authors： Malan TP Jr,Ibrahim MM,Vanderah TW,Makriyannis A,Porreca F

更新日期：2002-12-31 00:00:00

abstract：:Biological effects of foreign substances are usually caused by their interaction within lipid bilayers with the membrane lipids. It is therefore desirable in many situations to determine the effects and the partition of xenobiotic substances, as well as drugs, added to amphiphile-water systems. Bicontinuous cubic liqu...

journal_title：Chemistry and physics of lipids

authors： Engblom J

更新日期：1996-12-20 00:00:00

abstract：:Monitoring bile acids as signal molecules in combination with a bile acid synthesis marker and the FXR regulator fibroblast growth factor 19 (FGF19), this study addresses significant postprandial changes. The efficacy of the different pathways to regulate bile acid synthesis through short heterodimer partner (SHP) dep...

journal_title：Chemistry and physics of lipids

authors： Matysik S,Martin J,Bala M,Scherer M,Schäffler A,Schmitz G

更新日期：2011-09-01 00:00:00

abstract：:DNA interactions with the bilayers of cationic liposomes were studied using a novel model experiment: DNAs were locally injected by a micropipette to a part of a giant unilamellar vesicle. The resulting phenomena were directly observed in optical microscope. Giant unilamellar vesicles (GUVs), about 100 microm in diame...

journal_title：Chemistry and physics of lipids

authors： Angelova MI,Tsoneva I

更新日期：1999-08-01 00:00:00

abstract：:Under condition of ROS formation in lipid membranes, free radical reactions can proceed in both hydrophobic (peroxidation of lipids, POL) and polar (free radical fragmentation) parts of the bilayer. Free-radical fragmentation is typical for the lipids containing a hydroxyl group in β-position with respect to an ester ...

journal_title：Chemistry and physics of lipids

authors： Olshyk VN,Melsitova IV,Yurkova IL

更新日期：2014-01-01 00:00:00

abstract：:A method using liquid chromatography - atmospheric pressure chemical ionisation mass spectrometry was evaluated for determining the molecular species composition of phospholipids (phosphatidylcholines from soybean, egg yolk and bovine liver) after conversion to diacylglycerol nicotinate derivatives. The structures cou...

journal_title：Chemistry and physics of lipids

authors： Dobson G,Deighton N

更新日期：2001-05-01 00:00:00

abstract：:Structural analysis, a purification scheme and stability information on a fluorescent cholesterol analogue, which has been used as a probe in several model and biological systems, are presented. The proposed structure for the fluorophore, cholestatrien-3 beta-ol, closely resembles that of cholesterol. However, problem...

journal_title：Chemistry and physics of lipids

authors： Fischer RT,Stephenson FA,Shafiee A,Schroeder F

更新日期：1984-11-01 00:00:00

abstract：:A complex mixture of monoacylglycerols, identified as (C30--C36) corynomycoloylglycerols was isolated from the diethyl ether/acetone-soluble lipids of Corynebacterium pseudotuberculosis. ...

journal_title：Chemistry and physics of lipids

authors： Ioneda T,Silva CL

更新日期：1979-09-01 00:00:00

abstract：:The permeability of liposomes to water, glucose, Ca2+ and alkaline cations was monitored by recording the change in absorbance at 450 nm using a rapid reaction stopped-flow spectrophotometer. Liposomes were prepared with egg phosphatidylcholine and concentrations of dolichol ranging from 0.1% to 9% (w/w). Net permeabi...

journal_title：Chemistry and physics of lipids

authors： Boscoboinik DO,Feliz M,Disalvo EA,Belocopitow E

更新日期：1985-11-01 00:00:00

abstract：:Platelet activating factor is one of the most potent inflammatory ether phospholipid mediators known and structurally modified analogues are of considerable interest as potential therapeutic preparations. Inspired by the proposed structure for a novel endogenous hydroxy-PAF analogue isolated recently from gingival cre...

journal_title：Chemistry and physics of lipids

authors： Karantonis HC,Pitsinos EN,Antonopoulou S,Couladouros EA,Demopoulos CA

更新日期：2005-12-01 00:00:00

abstract：:N-Acyl tris(hydroxymethyl)aminomethanes (N-acyl tris, NATs) are structural analogs of ceramides, which were reported to induce apoptosis either by elevation of ceramide levels or by activation of pro-apoptotic effectors that are physiological targets of ceramide. In this study, we synthesized and characterized a homol...

journal_title：Chemistry and physics of lipids

authors： D S,Ravindar C,Swamy MJ

更新日期：2018-12-01 00:00:00