Intracranial pseudolymphoma.

abstract：:Anaplastic ganglioglioma (AGG) are rare central nervous system tumours. Patient and treatment factors associated with outcome are poorly defined and limited to small retrospective case series and single case reports. Using the Surveillance, Epidemiology, and End Results (SEER) cancer registry, we investigated potentia...

journal_title：Journal of neuro-oncology

authors： Selvanathan SK,Hammouche S,Salminen HJ,Jenkinson MD

更新日期：2011-12-01 00:00:00

abstract：:The Notch signal regulates both cell viability and apoptosis, and maintains stemness of various cancers including glioblastoma (GBM). Although Notch signal inhibition may be an effective strategy in treating GBM initiating cells (GICs), its applicability to the different subtypes of GBM remains unclear. Here, we analy...

journal_title：Journal of neuro-oncology

authors： Tanaka S,Nakada M,Yamada D,Nakano I,Todo T,Ino Y,Hoshii T,Tadokoro Y,Ohta K,Ali MA,Hayashi Y,Hamada J,Hirao A

更新日期：2015-01-01 00:00:00

abstract：:A rat glioma model was employed to estimate the Ca2+ kinetics in the tumor arteriolar smooth muscle cells. Electron microcytochemistry revealed that the density of intracellular Ca2+ deposits in the intra-tumor arteriolar smooth muscle cells was significantly greater, with slightly higher membrane Ca(2+)-adenosine tri...

journal_title：Journal of neuro-oncology

authors： Zenke K,Nakagawa K,Kumon Y,Ohta S,Hatakeyama T,Sakaki S

更新日期：1996-10-01 00:00:00

abstract：:In sporadic schwannomas, inactivation of both copies of the NF2 tumor suppressor gene on 22q is common. Constitutional mutations of SMARCB1 are responsible of schwannomatosis, an inherited tumor predisposition syndrome, characterized by the development of multiple schwannomas. We analysed the frequency of copy number ...

journal_title：Journal of neuro-oncology

authors： Paganini I,Capone GL,Vitte J,Sestini R,Putignano AL,Giovannini M,Papi L

更新日期：2018-03-01 00:00:00

abstract：:Children with a brain tumor (BT) are at risk for a number of physical and cognitive problems that may lower their health-related quality of life (HRQoL). Executive functioning (EF) and intellectual ability are hypothesized to associate with HRQoL and deficits in these areas may be amenable to interventions. This study...

journal_title：Journal of neuro-oncology

authors： Netson KL,Ashford JM,Skinner T,Carty L,Wu S,Merchant TE,Conklin HM

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:To report outcomes of salvage re-irradiation (re-RT) in recurrent/progressive medulloblastoma (MB). METHODS:Medical records of patients treated with curative-intent re-RT as multi-modality management for recurrent/progressive MB between 2008 and 2018 were analyzed retrospectively. RESULTS:A total of 28 patien...

journal_title：Journal of neuro-oncology

authors： Gupta T,Maitre M,Sastri GJ,Krishnatry R,Shirsat N,Epari S,Sahay A,Chinnaswamy G,Patil V,Shetty P,Moiyadi A

更新日期：2019-09-01 00:00:00

abstract：:Despite the accumulating evidences of high chemosensitivity especially in anaplastic oligodendrogliomas with loss of chromosomes 1p and 19q, the optimal management strategy for low-grade tumors using the 1p/19q information remains controversial. We have treated all low-grade oligodendrogliomas by a chemotherapy-preced...

journal_title：Journal of neuro-oncology

authors： Iwadate Y,Matsutani T,Hasegawa Y,Shinozaki N,Higuchi Y,Saeki N

更新日期：2011-05-01 00:00:00

abstract：:The mainstays of primary treatment of ependymoma are aggressive surgery followed by radiotherapy. Although spreading occasionally occurs in the cerebrospinal pathways, chemotherapy is still not established and no ultimate drug has so far been found. Estramustine-phosphate (EMP), with a demonstrated effect on astrocyto...

journal_title：Journal of neuro-oncology

authors： Bergenheim AT,Hartman M,Bergh J,Ridderheim PA,Henriksson R

更新日期：1994-01-01 00:00:00

abstract：:Temozolomide (TMZ) alone has been proposed as a promising alternative to radiotherapy (RT) in elderly glioblastoma (GBM) patients. We report a meta-analysis to systematically evaluate TMZ monotherapy in older GBM patients. A systematic literature search was performed using PubMed, EMBASE and the Cochrane database. Stu...

journal_title：Journal of neuro-oncology

authors： Yin AA,Cai S,Dong Y,Zhang LH,Liu BL,Cheng JX,Zhang X

更新日期：2014-01-01 00:00:00

abstract：:Improvements in imaging are increasing the detection of multiple lesions in the setting of glioblastoma. Occasionally distant non-enhancing lesions may be identified which have the appearances of a multicentric low-grade glioma. We aimed to determine the incidence, prognostic significance and diagnostic value of this ...

journal_title：Journal of neuro-oncology

authors： Lasocki A,Gaillard F,Tacey MA,Drummond KJ,Stuckey SL

更新日期：2016-09-01 00:00:00

abstract：:In earlier studies, we demonstrated that intratumoral infusions of alloreactive cytotoxic T lymphocytes (aCTL), sensitized to the major histocompatibility complex (MHC) antigens of the host, effectively retarded the intracranial growth of Fischer 9L gliosarcoma. We further demonstrated that continuous in vitro exposur...

journal_title：Journal of neuro-oncology

authors： Paul DB,Read SB,Kulprathipanja NV,Gomez GG,Kleinschmidt-DeMasters BK,Schiltz PM,Kruse CA

更新日期：2003-08-01 00:00:00

abstract：:While surgery is proned in low-grade glioma (LGG), the invasion of functional areas frequently prevents a complete resection. We report the first case of a patient operated on for a left frontal LGG, diagnosed because of seizures, with partial resection due to an invasion of the controlateral hemisphere. Chemotherapy ...

journal_title：Journal of neuro-oncology

authors： Duffau H,Taillandier L,Capelle L

更新日期：2006-11-01 00:00:00

abstract：:Intra-cerebrospinal fluid chemotherapy (ICC) is used widely to treat or prevent neoplastic meningitis (NM), although its safety has not been thoroughly assessed. We aimed to analyse the incidence, severity and cause of the adverse reactions provoked by ICC in a cohort of onco-haematological patients. We retrospectivel...

journal_title：Journal of neuro-oncology

authors： Pardo-Moreno J,Fernández C,Arroyo R,Ruiz-Ocaña C,Aláez C,Cuadrado ML

更新日期：2015-11-01 00:00:00

abstract：:During glioma resection, 5-aminolevulinic acid (5-ALA) and fluorescein sodium (Fl-Na) are used for photodynamic tumor visualization. The objective of this study was to evaluate the pathological findings of the boundary zone between the tumor and adjacent normal brain in glioblastoma patients undergoing simultaneous do...

journal_title：Journal of neuro-oncology

authors： Yano H,Nakayama N,Ohe N,Miwa K,Shinoda J,Iwama T

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Recent studies suggest a relatively high prevalence of autoimmune disorders (AD) among primary CNS lymphoma (PCNSL) patients, however, the literature is limited to case reports. To gain a better understanding of AD-PCNSL we reviewed and analyzed all cases described in the literature. METHODS:We searched the...

journal_title：Journal of neuro-oncology

authors： Kaulen LD,Karschnia P,Dietrich J,Baehring JM

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:Elongation of telomeres is necessary for tumor cell immortalization and senescence escape; neoplastic cells use to alternative pathways to elongate telomeres: telomerase reactivation or a telomerase-independent mechanism termed alternative lengthening of telomeres (ALT). Telomerase and ALT pathway has been expl...

journal_title：Journal of neuro-oncology

authors： Minasi S,Baldi C,Pietsch T,Donofrio V,Pollo B,Antonelli M,Massimino M,Giangaspero F,Buttarelli FR

更新日期：2019-05-01 00:00:00

abstract：:Little is known on the natural history, recurrence patterns, neurocognitive outcomes and prognostic factors associated with survival in long-term survivors (≥10 years) from brain metastasis (BM). In this study, the records of 1953 patients who underwent treatment for BM with a potential for ≥10 years of follow-up were...

journal_title：Journal of neuro-oncology

authors： Kotecha R,Vogel S,Suh JH,Barnett GH,Murphy ES,Reddy CA,Parsons M,Vogelbaum MA,Angelov L,Mohammadi AM,Stevens GHJ,Peereboom DM,Ahluwalia MS,Chao ST

更新日期：2016-09-01 00:00:00

abstract：INTRODUCTION:High hospital case volumes are associated with improved treatment outcomes for numerous diseases. We assessed the association between academic non-profit hospital case volume and survival of adult glioblastoma patients. METHODS:From the nationwide Finnish Cancer Registry, we identified all adult (≥ 18 yea...

journal_title：Journal of neuro-oncology

authors： Raj R,Seppä K,Luostarinen T,Malila N,Seppälä M,Pitkäniemi J,Korja M

更新日期：2020-04-01 00:00:00

abstract：:Intracranial metastatic prostate carcinoma is rare. We sought to determine the clinical outcomes after Gamma Knife stereotactic radiosurgery (GKSRS) for patients with intracranial prostate carcinoma metastases. We studied data from 10 patients who underwent radiosurgery for 15 intracranial metastases (9 dural-based an...

journal_title：Journal of neuro-oncology

authors： Flannery T,Kano H,Niranjan A,Monaco EA 3rd,Flickinger JC,Lunsford LD,Kondziolka D

更新日期：2010-02-01 00:00:00

abstract：:A case of multiple brain metastases from breast carcinoma treated with tamoxifen is described. She remained in remission for 58 months and is still alive after 82+ months of hormone therapy. The case indicates that hormonal treatment may be very effective in the management of brain metastases from breast carcinoma. ...

journal_title：Journal of neuro-oncology

authors： Pors H,von Eyben FE,Sørensen OS,Larsen M

更新日期：1991-04-01 00:00:00

abstract：INTRODUCTION:This study evaluated an association between whole brain volume loss and neurocognitive decline following prophylactic cranial irradiation (PCI) for limited-stage small-cell lung cancer (SCLC). METHODS:This was a secondary analysis of a prospective clinical trial that accrued patients at a single instituti...

journal_title：Journal of neuro-oncology

authors： Gui C,Chintalapati N,Hales RK,Voong KR,Sair HI,Grimm J,Duhon M,Kleinberg LR,Vannorsdall TD,Redmond KJ

更新日期：2019-09-01 00:00:00

abstract：SUBJECT:To date there is no established tumor marker for the clinical follow-up of glioblastoma, WHO grade IV, (GBM) which constitutes the most frequent and malignant primary brain tumor. However, since there is promising data that the serum glial fibrillary acidic protein (sGFAP) may serve as a biomarker for glial bra...

journal_title：Journal of neuro-oncology

authors： Baumgarten P,Quick-Weller J,Gessler F,Wagner M,Tichy J,Forster MT,Foerch C,Seifert V,Mittelbronn M,Senft C

更新日期：2018-09-01 00:00:00

abstract：:The effectiveness of radiotherapy and chemotherapy in high grade gliomas (HGG) depends on tumor micro-environment. We summarize our experience of the influence of spinal cord stimulation (SCS) on this micro-environment. Patients with HGG (n = 26) were assessed pre- and post-SCS, using: (1) Doppler in middle cerebral a...

journal_title：Journal of neuro-oncology

authors： Clavo B,Robaina F,Valcarcel B,Catala L,Perez JL,Cabezon A,Jorge IJ,Fiuza D,Hernandez MA,Jover R,Carreras JL

更新日期：2012-01-01 00:00:00

abstract：:We prospectively evaluated the efficacy and safety of imatinib plus hydroxyurea in patients with progressive/recurrent meningioma. A total of 21 patients with progressive/recurrent meningioma were enrolled in this dual center, single-arm, phase II trial. All patients received 500 mg of hydroxyurea twice a day. Imatini...

journal_title：Journal of neuro-oncology

authors： Reardon DA,Norden AD,Desjardins A,Vredenburgh JJ,Herndon JE 2nd,Coan A,Sampson JH,Gururangan S,Peters KB,McLendon RE,Norfleet JA,Lipp ES,Drappatz J,Wen PY,Friedman HS

更新日期：2012-01-01 00:00:00

abstract：:The labeling index (LI) of 216 cases of human brain tumors was determined by the immunohistochemical technique with monoclonal antibody to bromodeoxyuridine (BrdU). The proliferative potential of 110 cases was estimated using the intra-operative intravenous infusion of BrdU at a dose of 200 mg/sq m. In another 106 cas...

journal_title：Journal of neuro-oncology

authors： Kharbanda K,Dinda AK,Sarkar C,Karak AK,Dhir R,Mathur M,Roy S

更新日期：1995-01-01 00:00:00

abstract：:NeuroCogFX is a short yet comprehensive computer-based neuropsychological battery of tests developed to investigate neurological patients for cognitive dysfunction after potentially neurotoxic therapy. NeuroCogFX had been standardized in a group of 242 healthy controls (Fliessbach et al., Fortschr Neurol Psychiatr 74:...

journal_title：Journal of neuro-oncology

authors： Fliessbach K,Rogowski S,Hoppe C,Sabel M,Goeppert M,Helmstaedter C,Calabrese P,Schackert G,Tonn JC,Simon M,Schlegel U

更新日期：2010-12-01 00:00:00

abstract：:The antiproliferative effect of IFNalpha was tested on the human glioblastoma cell lines, U-373MG and T98G. IFNalpha significantly inhibited the growth of both cell lines, but was more effective in retarding the growth of U-373MG cells. Flow cytometry analysis indicated that synchronized IFNalpha-treated U-373MG cells...

journal_title：Journal of neuro-oncology

authors： Tanabe T,Kominsky SL,Subramaniam PS,Johnson HM,Torres BA

更新日期：2000-07-01 00:00:00

abstract：PURPOSE:Therapeutic intervention at glioblastoma (GBM) progression, as defined by current assessment criteria, is arguably too late as second-line therapies fail to extend survival. Still, most GBM trials target recurrent disease. We propose integration of a novel imaging biomarker to more confidently and promptly defi...

journal_title：Journal of neuro-oncology

authors： Gatson NTN,Bross SP,Odia Y,Mongelluzzo GJ,Hu Y,Lockard L,Manikowski JJ,Mahadevan A,Kazmi SAJ,Lacroix M,Conger AR,Vadakara J,Nayak L,Chi TL,Mehta MP,Puduvalli VK

更新日期：2020-07-01 00:00:00

abstract：:Ependymomas (EPN) show site specific genetic alterations and a recent DNA methylation profiling study identified nine molecular subgroups. C11orf95-RELA and YAP1 fusions characterise the RELA and YAP1 molecular subgroups, respectively, of supratentorial (ST)-EPNs. Current guidelines recommend molecular subgrouping ove...

journal_title：Journal of neuro-oncology

authors： Malgulwar PB,Nambirajan A,Pathak P,Faruq M,Rajeshwari M,Singh M,Suri V,Sarkar C,Sharma MC

更新日期：2018-05-01 00:00:00

abstract：INTRODUCTION:Intracranial meningiomas rarely present with multiple lesions. To the best of our knowledge, current literature regarding meningiomatosis (MM) is mostly comprised of small case series and individual reports. Hence, survival outcome data are limited. The Objective of this study is to explore the influence o...

journal_title：Journal of neuro-oncology

authors： Ramos-Fresnedo A,Domingo RA,Vivas-Buitrago T,Lundy L,Trifiletti DM,Jentoft ME,Desai AB,Quiñones-Hinojosa A

更新日期：2020-09-01 00:00:00