Sequence-dependent antagonism between tamoxifen and methotrexate in human breast cancer cells.

abstract：:The multifactorial process of carcinogenesis in the digestive system involves mutations in oncogenes or tumor suppressor genes, as well as influence of environmental etiological factors. In recent years, common DNA polymorphisms in low penetrance genes emerged as genetic factors that seem to modulate an individual's s...

journal_title：Anticancer research

authors： Tsigris C,Chatzitheofylaktou A,Xiromeritis C,Nikiteas N,Yannopoulos A

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND/AIM:The purpose of this study was to identify adverse prognostic factors for patients with advanced esophageal cancer undergoing chemotherapy with docetaxel, cisplatin and 5-fluorouracil (DCF). PATIENTS AND METHODS:The study cohort comprised of 45 patients with advanced esophageal cancer who underwent induc...

journal_title：Anticancer research

authors： Nakajima M,Muroi H,Kikuchi M,Takahashi M,Ihara K,Shida Y,Kurayama E,Ogata H,Yamaguchi S,Sasaki K,Sakai M,Sohda M,Miyazaki T,Kuwano H,Kato H

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND/AIM:This study aimed to identify the survival benefit of intrahepatic tumour control by hepatic arterial infusion chemotherapy (HAIC) in hepatocellular carcinoma (HCC) patients with portal vein tumour thrombus (PVTT) or extrahepatic metastasis. PATIENTS AND METHODS:Between 2010 and 2017, a total of 187 cons...

journal_title：Anticancer research

authors： Sung PS,Yang K,Bae SH,Oh JS,Chun HJ,Nam HC,Jang JW,Choi JY,Yoon SK

更新日期：2019-07-01 00:00:00

abstract：:There is sparse information about cancer in the axillary tail of Spence (CATS). Eight hundred and thirty-nine patients with breast cancer were retrospectively studied for the occurrence of CATS. Ten patients were identified based on detection by imaging studies. A tendency towards stage II or III disease, and estrogen...

journal_title：Anticancer research

authors： Ampil F,Caldito G,Henderson B,Li B,Kim RH,Burton G,Chu Q

更新日期：2012-09-01 00:00:00

abstract：:A consecutive series of 128 breast cancer patients detected by breast screening were enrolled in this study to analyze their age-dependent characteristics. They were classified into three groups; 40 years or less (young): 26 patients, 41-55 years (middle-aged): 67 patients and 56 years or over (old): 35 patients. The ...

journal_title：Anticancer research

authors： Takei H,Iino Y,Horiguchi J,Maemura M,Koibuchi Y,Horii Y,Nagaoka H,Matsumoto H,Ishikita T,Yokoe T,Morishita Y

更新日期：1998-07-01 00:00:00

abstract：:To evaluate the treatment-related late sequelae including gonadal function and second malignancy 94 patients with stage I and II testicular seminoma treated with postorchiectomy radiation therapy were analyzed retrospectively. The 10-year cause specific, disease free and actuarial survival rates were 100, 98.5 and 96....

journal_title：Anticancer research

authors： Akimoto T,Takahashi I,Takahashi M,Yamakawa M,Hayakawa K,Mitsuhashi N,Niibe H

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Protein kinase C (PKC) activity is increased and gap junctional intercellular communication (GJIC) is decreased frequently in Ras-transformed cells. We investigated the roles of Ras and PKC in the deficient gap junctional intercellular communication (GJIC) of K-ras-transformed E9 mouse lung carcinoma cells. ...

journal_title：Anticancer research

authors： Cesen-Cummings K,Warner KA,Ruch RJ

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND/AIM:Advanced anaplastic thyroid cancer (ATC) is a rare, but highly aggressive malignancy, and its prognostic factors need to be further explored. We examined socioeconomic factors' predictive effect for survival performance in stage IV ATC patients. MATERIALS AND METHODS:Using the Surveillance, Epidemiology...

journal_title：Anticancer research

authors： Li MU,Gu S,Mao R,Ning Y,Trivedi N,Siddiqui A,Li P,Huo L

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Increasing evidence suggests that COX-2 promotes carcinogenesis but it is controversial as to whether COX-2 expression is a prognostic factor for rectal carcinoma. MATERIALS AND METHODS:Data of 62 consecutive patients with rectal carcinoma in UICC-stages I-III, which were curatively resected between 1995 an...

journal_title：Anticancer research

authors： Petersen S,Haroske G,Hellmich G,Ludwig K,Petersen C,Eicheler W

更新日期：2002-03-01 00:00:00

abstract：:Recently hormone - dependent mammary carcinoma cell lines were shown to exhibit in vitro significantly lower protein kinase C (PKC) activities and epidermal growth factor receptor (EGF-R) as compared to hormone - independent cell lines. Measurements of EGF-R levels in primary human breast cancer biopsies were determin...

journal_title：Anticancer research

authors： Wyss R,Fabbro D,Regazzi R,Borner C,Takahashi A,Eppenberger U

更新日期：1987-07-01 00:00:00

abstract：:Urine and serum samples from a group of 359 individuals were studied in order to evaluate the usefulness of TPA in patients with urological cancers. Serum was taken from 110 people at 12 noon (S1), 5 pm (S2), and 8 am the following day (S3), while urine samples were collected from 73 individuals over three time interv...

journal_title：Anticancer research

authors： Costello CB,Kumar S

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:Using three commercially available, unmodified PSA assays, 917 sera of 355 patients after radical prostatectomy underwent native and lyophilisation-concentrated PSA-detection to evaluate the benefit of serum concentration as a tool to increase sensitivity for earlier detection of recurrent prostate cancer af...

journal_title：Anticancer research

authors： Haese A,Huland E,Graefen M,Huland H

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Concurrent chemoradiotherapy (CCRT) is used to treat advanced head and neck cancer. The accuracy of evaluating lymph nodes metastases following CCRT is important for subsequent therapy. PATIENTS AND METHODS:Patients were divided into two groups, the complete response (CR) and the non-CR groups, as determine...

journal_title：Anticancer research

authors： Nishimura G,Matsuda H,Taguchi T,Takahashi M,Komatsu M,Sano D,Sakuma N,Arai Y,Takahashi H

更新日期：2012-02-01 00:00:00

abstract：UNLABELLED:We investigated the predictive value of the protein S100 as a tumor-marker in the post-surgical follow-up staging of patients with High Risk melanomas (Clark Levels IV/V, Thickness > 0.75 mm). METHODS:In 51 follow-up studies, performed in 50 patients, serum concentrations of the protein S100 were measured a...

journal_title：Anticancer research

authors： Mruck S,Baum RP,Rinne D,Hör G

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND/AIM:FAM92A1-289 is recognized as one of the newly-discovered putative oncogenes. This study was performed to reveal its oncogenic functions in human cervical carcinoma cells. MATERIALS AND METHODS:The FAM92A1-289+ cell line was established with knock-in technique and selected by puromycin-resistance screeni...

journal_title：Anticancer research

authors： Gui H,Guo XR,Fang J,Ma SN,Wu G,Shen JH,Tu HJ,Li DS,Dai LJ,Ruan XZ

更新日期：2016-10-01 00:00:00

abstract：:Cancer is mostly environmental in origin and therefore is theoretically preventable by control of environmental conditions. From the viewpoint of the natural history of cancer, the multi-step nature of neoplasia and the generally long latent period are stressed. The molecular biology of cancer tells us that neoplasia ...

journal_title：Anticancer research

authors： Sugano H

更新日期：1999-09-01 00:00:00

abstract：:Local control was compared between patients who had undergone breast-conserving therapy with and without nipple resection. We explored whether there was any difference in local control between the two treatment methods for patients with early breast cancer. A total of 333 women with breast cancer, who had undergone br...

journal_title：Anticancer research

authors： Horiguchi J,Koibuchi Y,Iijima K,Yoshida T,Takata D,Rokutanda N,Nagaoka R,Oyama T,Iino Y,Sakurai H,Morishita Y

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND/AIM:In order to develop an efficient drug-delivery system (DDS), a lipopeptide-loaded liposome that functions as a platform for the transpeptidase reaction mediated by sortase A (SrtA) was constructed and its stability, as well as cell-specific targeting were evaluated in the present study. MATERIALS AND ME...

journal_title：Anticancer research

authors： Tabata A,Ohkubo Y,Anyoji N,Hojo K,Tomoyasu T,Tatematsu Y,Ohkura K,Nagamune H

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Chemotherapeutic anticancer properties are thought to derive from apoptosis pathway activation and/or cell division arrest, but animal models have also evidenced anti-angiogenic activity in some agents. PATIENTS AND METHODS:The impact of gemcitabine, irinotecan and oxaliplatin + 5-FU upon the serum markers ...

journal_title：Anticancer research

authors： Bellone G,Novarino A,Chiappino I,Gramigni C,Carbone A,Addeo A,Tonel E,Bertetto O,Emanuelli G

更新日期：2005-09-01 00:00:00

abstract：:To date over 60 different human papilloma virus (HPV) types have been described and novel HPV genomes are still being identified. The identification and taxonomy of papilloma viruses has become increasingly complex However, some types, especially HPV-16, -18 and to a lesser extent HPV-31 and -33, which are found in a ...

journal_title：Anticancer research

authors： Troungos C,Horti M,Kittas C

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND/AIM:The significance of microvascular invasion (MVI) of hepatocellular carcinoma (HCC) after radiofrequency ablation (RFA) is unknown. PATIENTS AND METHODS:We studied 149 patients with solitary small-sized HCC (≤3 cm) who underwent hepatectomy, and developed a predictive model of MVI using independent facto...

journal_title：Anticancer research

authors： Imai K,Yamashita YI,Yusa T,Nakao Y,Itoyama R,Nakagawa S,Okabe H,Chikamoto A,Ishiko T,Baba H

更新日期：2018-02-01 00:00:00

abstract：:Since long, oxidative stress-driven modifications in breast cancer were faced as detrimental cellular events that cause obligatory cell damage. Recent studies show that the products generated during redox reactions are able to modulate pivotal processes regarding breast cancer survival, proposing a new way of looking ...

journal_title：Anticancer research

authors： Mencalha A,Victorino VJ,Cecchini R,Panis C

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Screening gastroscopic examinations were performed in a cohort of individuals at high risk for developing gastric carcinoma (GC). PATIENTS AND METHODS:Five gastric biopsies were obtained following the Houston schema. Five histological parameters of gastritis were investigated: acute gastritis, chronic gastr...

journal_title：Anticancer research

authors： Saieva C,Rubio CA,Nesi G,Zini E,Filomena A

更新日期：2012-05-01 00:00:00

abstract：:The effects of NAMI-A, a novel ruthenium compound endowed with selective antimetastatic action, were tested on solid metastasising tumours of the mouse in comparison to cisplatin, cyclophosphamide and dacarbazine. Each compound was administered i.p. as freshly prepared solutions in isotonic saline in combination with ...

journal_title：Anticancer research

authors： Sava G,Gagliardi R,Bergamo A,Alessio E,Mestroni G

更新日期：1999-03-01 00:00:00

abstract：:We have previously reported that the presence of an extracapsular invasion (ECI) at sentinel lymph nodes (SLNs) is a strong predictor of non-SLN metastasis in breast cancer. We hypothesized that(18)F-fluorodeoxyglucose (FDG) uptake by metastatic SLNs reflects invasive disease, or ECI. In this study, we evaluated the a...

journal_title：Anticancer research

authors： Fujii T,Yajima R,Tatsuki H,Kuwano H

更新日期：2016-04-01 00:00:00

abstract：:Tumor growth delay (TGD) is a widely accepted method for in situ assessment of tumor treatment modalities. However, it has some drawbacks: (1) dependency on arbitrary endpoints and, even more serious, (2) lack of alterations of the tumor-growth pattern after treatment. In the present study a generalization of TGD is p...

journal_title：Anticancer research

authors： Bassukas ID

更新日期：1993-09-01 00:00:00

abstract：:Giant cell tumor (GCT) is a relatively common and locally aggressive benign bone tumor. The sternum is a rare location. To date, only four cases have been reported with detailed information. Here, we present a case with sternal GCT and discuss the clinical manifestation and treatment, in addition to reviewing the lite...

journal_title：Anticancer research

authors： Futani H,Okumura Y,Fukuda Y,Fukunaga S,Hasegawa S,Yoshiya S

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:During the complex process of melanoma cell detachment from the primary tumor and subsequent metastasis, different cell surface proteins are involved in tumor cell interactions with extracellular matrix (ECM) components and surrounding cells. Melanoma cells are able to vary their expression patterns of adhes...

journal_title：Anticancer research

authors： Laube F

更新日期：2007-07-01 00:00:00

abstract：AIM:To investigate whether the negative quality of life result of a large randomized exercise intervention study (BREX) was due to considerable spontaneous recovery after adjuvant treatments. PATIENTS AND METHODS:The change in QoL was studied in the control patients of the BREX study (Group 1) and a group of similar f...

journal_title：Anticancer research

authors： Penttinen H,Rautalin M,Roine R,Jahkola T,Kellokumpu-Lehtinen PL,Huovinen R,Kautiainen H,Järvenpää S,Hakamies-Blomqvist L,Blomqvist C,Saarto T

更新日期：2014-03-01 00:00:00

abstract：:Our investigation comprises 778 cases of resection for early gastric cancer (27.4% of all stomach resections). The rate of lymph node metastasis was 1.2% in m (mucosal cancer) group, 3.3% in sm (submucosal cancer) 1 group and 22.6% in sm 2 group. In sm 2 group, lymph node extirpation of R2 is essential. The five year ...

journal_title：Anticancer research

authors： Kito T,Yamamura Y,Kobayashi S

更新日期：1988-05-01 00:00:00