Erythema exsudativum multiforme induced by granulocyte colony-stimulating factor in an allogeneic peripheral blood stem cell donor.

Abstract:

:We describe a healthy peripheral blood stem cell (PBSC) donor who developed a cutaneous reaction, erythema exsudativum multiforme, during the administration of granulocyte colony-stimulating factor (G-CSF) for mobilization. The cutaneous lesions were located on his hips, apart from the site of G-CSF injection. Treatment with topical corticosteroid was commenced, and the lesions resolved completely within a week. Adverse cutaneous reactions induced by G-CSF have been reported infrequently in healthy donors. Further documentation of cases and their full evaluation will be of great importance for both physicians and PBSC donor.

journal_name

Bone Marrow Transplant

authors

Mori T,Sato N,Watanabe R,Okamoto S,Ikeda Y

doi

10.1038/sj.bmt.1702501

subject

Has Abstract

pub_date

2000-07-01 00:00:00

pages

239-40

issue

2

eissn

0268-3369

issn

1476-5365

journal_volume

26

pub_type

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