当前位置： SCI文献检索 > EPILEPSIA期刊下所有文献 > Relationships between seizure severity and health-related quality of life in refractory localization-related epilepsy.

Relationships between seizure severity and health-related quality of life in refractory localization-related epilepsy.

Abstract：

PURPOSE:To evaluate relationships between self-report measures of seizure severity and health-related quality of life (HRQOL) in people with refractory localization-related epilepsy. METHODS:A sample of 340 adults enrolled in a seven-center, prospective study of resective epilepsy surgery completed baseline questionnaires that included the Quality of Life in Epilepsy (QOLIE)-89 and a seven-item adaptation of the National Hospital Seizure Severity Scale. Associations between QOLIE-89 summary measures and both the total seizure severity scale score and individual seizure severity items were assessed, after adjustment for seizure frequency. RESULTS:The seizure severity measure had adequate scale score variability and reliability in this sample. Correlations between individual items in the scale did not exceed 0. 43. Product-moment partial correlations between the seizure severity scale and QOLIE-89 summary measures ranged from -0.17 to -0.29 (all p values <0.01). Of the seven seizure severity items, the average time before individuals perceived they were "really back to normal" after their seizures was broadly related to all domains of HRQOL (r values ranged from -0.16 to -0.30; p values <0.01). Severity of injury during seizures was the only other item having more than minimal associations with HRQOL, and it was selectively related to the physical health measure. Higher frequency of falls during seizures was modestly related to less employment. CONCLUSIONS:This seizure severity measure assesses constructs that are generally distinct from HRQOL, except for moderate and broad associations between HRQOL and patient's perceptions of the average duration of recovery time after seizures. Recovery time may potentially be a useful clinical indicator of seizure severity that reflects meaningful impairment of HRQOL in adults with frequent seizures.

journal_name

Epilepsia

journal_title

Epilepsia

authors

Vickrey BG,Berg AT,Sperling MR,Shinnar S,Langfitt JT,Bazil CW,Walczak TS,Pacia S,Kim S,Spencer SS

doi

10.1111/j.1528-1157.2000.tb00239.x

subject

Has Abstract

pub_date

2000-06-01 00:00:00

pages

760-4

issue

6

eissn

0013-9580

issn

1528-1167

journal_volume

41

pub_type

临床试验,杂志文章,多中心研究

相关文献

EPILEPSIA文献大全
  • Double pathology in Rasmussen's encephalitis: etiologic considerations.

    abstract：:In a 7-year-old girl with epilepsia partialis continua (EPC) involving the left face, arm, and leg for 1 year, serial neuroimaging studies showed progressive, brain atrophy. Because medical treatment was ineffective, she underwent a large fronto-temporal surgical resection. Neuropathological examination showed loss of...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/j.1528-1157.1996.tb00597.x

    authors： Yacubian EM,Rosemberg S,Marie SK,Valério RM,Jorge CL,Cukiert A

    更新日期：1996-05-01 00:00:00

  • Psychiatric outcome after temporal lobectomy: a predictive study.

    abstract：PURPOSE:The occurrence of psychiatric symptoms after temporal lobectomy is well documented. The aim of the present study was to identify preoperative factors that predict postoperative psychiatric outcome. METHODS:We studied the case notes of 121 patients (from an initial sample of 167) who underwent temporal lobectom...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/j.1499-1654.2000.001608.x

    authors： Anhoury S,Brown RJ,Krishnamoorthy ES,Trimble MR

    更新日期：2000-12-01 00:00:00

  • Sodium valproate associated with phenobarbital: effects on ammonia metabolism in humans.

    abstract：:Treatment with sodium valproate (VPA) in association with phenobarbital (PB) is accompanied by a greater systemic hyperammonemia than treatment by VPA alone. The anatomical origins of this difference were studied by injecting a dose of 1,500 mg VPA i.v. into six unmedicated patients and six epileptics chronically trea...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/j.1528-1157.1983.tb03428.x

    authors： Warter JM,Marescaux C,Brandt C,Rumbach L,Micheletti G,Chabrier G,Imler M,Kurtz D

    更新日期：1983-10-01 00:00:00

  • Development of intelligence and neuropsychological impairment scales for the Washington Psychosocial Seizure Inventory.

    abstract：:The Washington Psychosocial Seizure Inventory (WPSI) was used to evaluate the relative extent of psychosocial problems in 379 adults with epilepsy, having differing levels of intelligence and neuropsychological impairment. In general, there were more psychosocial problems when abilities were decreased. Two new scales ...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/j.1528-1157.1983.tb04859.x

    authors： Dodrill CB

    更新日期：1983-02-01 00:00:00

  • Recommendations of the Italian League against Epilepsy working group on generic products of antiepileptic drugs.

    abstract：:The availability of generic products of antiepileptic drugs (AEDs) has been increasing in recent years. In view of the importance of the issue, the Italian League against Epilepsy (LICE) set up an ad hoc working group whose task was to assess available evidence on the efficacy and safety of generic AEDs in the treatme...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/j.1528-1167.2006.00871.x

    authors： Perucca E,Albani F,Capovilla G,Bernardina BD,Michelucci R,Zaccara G

    更新日期：2006-01-01 00:00:00

  • Plasticity of excitatory amino acid transporters in experimental epilepsy.

    abstract：PURPOSE:To examine the relationship between seizures and excitatory amino acid transporter (EAAT) activity and whether up-regulation of EAAT activity alters epileptogenicity. METHODS:In this study, we exposed rat hippocampal slices to different convulsants before measuring EAAT activity. Rats were exposed to the EAAT ...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/j.1528-1157.2000.tb01567.x

    authors： Claudio OI,Ferchmin P,Velísek L,Sperber EF,Moshé SL,Ortiz JG

    更新日期：2000-01-01 00:00:00

  • Nonepileptic seizures in children.

    abstract：PURPOSE:To determine if the clinical characteristics of nonepileptic seizures (NES) are different in children younger than 13 years age as compared to adolescents. METHODS:Retrospective review of medical records and video-EEGs (VEEG) of all patients with NES confirmed on VEEG monitoring was performed. RESULTS:Sixty-e...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/j.1528-1167.2007.01200.x

    authors： Patel H,Scott E,Dunn D,Garg B

    更新日期：2007-11-01 00:00:00

  • Phenobarbital for the treatment of epilepsy in the 21st century: a critical review.

    abstract：SUMMARY:Phenobarbital (PB) is the most widely used antiepileptic drug (AED) in the developing world and remains a popular choice in many industrialized countries. Meta-analyses of randomized controlled trials suggest that few differences in efficacy exist between PB and other established AEDs, but its possible deleteri...

    journal_title：Epilepsia

    pub_type： 杂志文章,评审

    doi：10.1111/j.0013-9580.2004.12704.x

    authors： Kwan P,Brodie MJ

    更新日期：2004-09-01 00:00:00

  • Impact of idiopathic epilepsy on mothers and fathers: strain, burden of care, worries and perception of vulnerability.

    abstract：:The purpose of the study was to examine the impact of idiopathic epilepsy on mothers and fathers in terms of strain, burden of care, worries and perception of vulnerability. Data were collected and analyzed shortly after the diagnosis (T0) and 12 months later (T1). The results indicated that at T0 parents of children ...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/j.1528-1167.2007.01145.x

    authors： Ramaglia G,Romeo A,Viri M,Lodi M,Sacchi S,Cioffi G

    更新日期：2007-09-01 00:00:00

  • Defective visual inhibition in photosensitive idiopathic generalized epilepsy.

    abstract：PURPOSE:To assess the visual system excitability of photosensitive patients with idiopathic generalized epilepsy (IGE) with the paired-pulse flash-evoked potential (paired F-VEP) technique. METHODS:We studied 19 photosensitive patients with IGE (16 women) showing a photoparoxysmal electroencephalographic (EEG) respons...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/j.1528-1167.2012.03411.x

    authors： Strigaro G,Prandi P,Varrasi C,Monaco F,Cantello R

    更新日期：2012-04-01 00:00:00

  • SCN2A mutations and benign familial neonatal-infantile seizures: the phenotypic spectrum.

    abstract：:Mutations of the sodium channel subunit gene SCN2A have been described in families with benign familial neonatal-infantile seizure (BFNIS). We describe two large families with BFNIS and novel SCN2A mutations. The families had 12 and 9 affected individuals, respectively, with phenotypes consistent with BFNIS. Two mutat...

    journal_title：Epilepsia

    pub_type： 杂志文章,多中心研究

    doi：10.1111/j.1528-1167.2007.01049.x

    authors： Herlenius E,Heron SE,Grinton BE,Keay D,Scheffer IE,Mulley JC,Berkovic SF

    更新日期：2007-06-01 00:00:00

  • Health care expenditures among elderly patients with epilepsy in the United States.

    abstract：OBJECTIVE:The purpose of this study was to evaluate health care expenditures among elderly patients with epilepsy in the United States. METHODS:We performed an analysis of weighted 37 738 607 US participants aged 65 years to estimate health care expenditures in the elderly with and without epilepsy using the Medical E...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/epi.14455

    authors： Lekoubou A,Bishu KG,Ovbiagele B

    更新日期：2018-07-01 00:00:00

  • Some facts about sleep relevant for Landau-Kleffner syndrome.

    abstract：:Our understanding of the neural mechanisms of non-rapid eye movement sleep (NREM) is steadily increasing. Given the intriguing activation of paroxysmal activity during NREM sleep in patients with Landau-Kleffner syndrome (LKS), a thorough characterization of commonalities and differences between the neural correlates ...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/j.1528-1167.2009.02218.x

    authors： Mascetti L,Foret A,Bonjean M,Matarazzo L,Dang-Vu T,Maquet P

    更新日期：2009-08-01 00:00:00

  • Acute cerebral microbleeds in refractory status epilepticus.

    abstract：:Cerebral microbleeds (CMBs) are commonly found in patients with stroke and cerebral amyloid angiopathy. However, there have been no reports of CMBs or their acute appearance in patients with status epilepticus. Herein we describe two patients with refractory status epilepticus of uncertain origin. Both patients were p...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/epi.12113

    authors： Jeon SB,Parikh G,Choi HA,Lee K,Lee JH,Schmidt JM,Badjatia N,Mayer SA,Claassen J

    更新日期：2013-05-01 00:00:00

  • The effects of epilepsy and its treatment on sexual and reproductive function.

    abstract：:Male and female sexuality and reproductive functions are complex systems with cortical, limbic system, hypothalamic, pituitary, and end organ interactions. Sexual steroids are produced in the sexual glands, the adrenals, and the brain. They undergo interconversion in the brain, bind to different brain areas, and have ...

    journal_title：Epilepsia

    pub_type： 杂志文章,评审

    doi：10.1111/j.1528-1157.2000.tb01524.x

    authors： Penovich PE

    更新日期：2000-01-01 00:00:00

  • Do recent seizures and recent changes in antiepileptic drugs impact performances on neuropsychological tests in subtle ways that might easily be missed?

    abstract：PURPOSE:The possibility that a recent seizure or a recent change in antiepileptic medication might produce an occult change in neuropsychological performance is of interest, and especially so in the context of evaluation for epilepsy surgery. Such an evaluation is often done in a setting of video-EEG monitoring where a...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/j.1528-1167.2007.01140.x

    authors： Dodrill CB,Ojemann GA

    更新日期：2007-10-01 00:00:00

  • Increased deposition of cholesterol in brain after electroconvulsive seizure.

    abstract：:Rats injected intracranially with cholesterol precursors and subjected to electroconvulsive seizures showed significantly higher levels of deposition of [4-14C]cholesterol into brain cholesterol than controls. The degree of incorporation was cholesterol greater than mevalonic acid greater than sodium acetate; in each ...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/j.1528-1157.1983.tb03424.x

    authors： Colannino NM,Lipke H

    更新日期：1983-10-01 00:00:00

  • Blood-brain barrier dysfunction in brain diseases: clinical experience.

    abstract：:The blood-brain barrier, a unique feature of the cerebral vasculature, is gaining attention as a feature in common neurologic disorders including stroke, traumatic brain injury, epilepsy, and schizophrenia. Although acute blood-brain barrier dysfunction can induce cerebral edema, seizures, or neuropsychiatric symptoms...

    journal_title：Epilepsia

    pub_type： 杂志文章,评审

    doi：10.1111/j.1528-1167.2012.03697.x

    authors： Schoknecht K,Shalev H

    更新日期：2012-11-01 00:00:00

  • Systemic lupus erythematosus associated with use of valproate.

    abstract：:A 30-year-old man with long-standing localization-related epilepsy and mental retardation had seizures that were partially controlled with valproate (VPA) 500 mg four times daily. Routine examination showed severe thrombocytopenia with mild leukopenia and chronic low-grade hemolytic anemia. Pertinent laboratory result...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/j.1528-1157.1994.tb02927.x

    authors： Asconapé JJ,Manning KR,Lancman ME

    更新日期：1994-01-01 00:00:00

  • Genetics of photosensitivity (photoparoxysmal response): a review.

    abstract：:We present a review of phenotype-genotype correlation and the genetics of photosensitivity. The photoparoxysmal response in EEG (PPR) is still one of the best paradigms for exogenously triggered brain responses based on a genetic predisposition. The definition of the PPR phenotype requires multiple, precise methodolog...

    journal_title：Epilepsia

    pub_type： 杂志文章,评审

    doi：10.1111/j.0013-9580.2004.451008.x

    authors： Stephani U,Tauer U,Koeleman B,Pinto D,Neubauer BA,Lindhout D

    更新日期：2004-01-01 00:00:00

  • Lack of change in neurochemical markers during the postepileptic phase of intrahippocampal tetanus toxin syndrome in rats.

    abstract：:The chronic epileptic syndrome induced by injecting tetanus toxin into rat hippocampus causes functional changes that essentially are permanent, outlasting the period of active seizures by at least 1 year. These long-term changes have been characterized by an impaired performance on a range of behavioral tasks, which ...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/j.1528-1157.1990.tb05508.x

    authors： Francis PT,Lowe SL,Bowen DM,Jefferys JG

    更新日期：1990-11-01 00:00:00

  • Reduction in internal carotid arterial blood flow velocity in children during antiepileptic drug therapy with clinical dosages.

    abstract：:We studied the effect of antiepileptic drugs (AEDs) on internal carotid artery (ICA) blood flow velocity, as an index of total cerebral blood flow (CBF). The subjects were 45 newly diagnosed children with febrile convulsion or epilepsy who were seizure-free for a period long enough not to affect the results. They had ...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/j.1528-1157.1994.tb02519.x

    authors： Futagi Y,Otani K,Imai K

    更新日期：1994-07-01 00:00:00

  • Epilepsy in peroxisomal diseases.

    abstract：PURPOSE:To clarify the electroclinical manifestation of epileptic seizures and the evolution of epilepsy in patients with peroxisomal diseases. METHODS:Retrospective review of the medical records and EEGs of 14 patients with peroxisomal diseases: seven with Zellweger syndrome (ZS), two with neonatal adrenoleukodystrop...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/j.1528-1157.1997.tb01095.x

    authors： Takahashi Y,Suzuki Y,Kumazaki K,Tanabe Y,Akaboshi S,Miura K,Shimozawa N,Kondo N,Nishiguchi T,Terada K,Orii T

    更新日期：1997-02-01 00:00:00

  • Parahippocampal epilepsy with subtle dysplasia: A cause of "imaging negative" partial epilepsy.

    abstract：PURPOSE:Lesion-negative refractory partial epilepsy is a major challenge in the assessment of patients for potential surgery. Finding a potential epileptogenic lesion simplifies assessment and is associated with good outcome. Here we describe imaging features of subtle parahippocampal dysplasia in five cases that were ...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/j.1528-1167.2009.02103.x

    authors： Pillay N,Fabinyi GC,Myles TS,Fitt GJ,Berkovic SF,Jackson GD

    更新日期：2009-12-01 00:00:00

  • Withdrawal of valproic acid treatment during pregnancy and seizure outcome: Observations from EURAP.

    abstract：:Based on data from the EURAP observational International registry of antiepileptic drugs (AEDs) and pregnancy, we assessed changes in seizure control and subsequent AED changes in women who underwent attempts to withdraw valproic acid (VPA) during the first trimester of pregnancy. Applying Bayesian statistics, we comp...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/epi.13437

    authors： Tomson T,Battino D,Bonizzoni E,Craig J,Lindhout D,Perucca E,Sabers A,Thomas SV,Vajda F,EURAP Study Group.

    更新日期：2016-08-01 00:00:00

  • ILAE official report: a practical clinical definition of epilepsy.

    abstract：:Epilepsy was defined conceptually in 2005 as a disorder of the brain characterized by an enduring predisposition to generate epileptic seizures. This definition is usually practically applied as having two unprovoked seizures >24 h apart. The International League Against Epilepsy (ILAE) accepted recommendations of a t...

    journal_title：Epilepsia

    pub_type： 杂志文章,评审

    doi：10.1111/epi.12550

    authors： Fisher RS,Acevedo C,Arzimanoglou A,Bogacz A,Cross JH,Elger CE,Engel J Jr,Forsgren L,French JA,Glynn M,Hesdorffer DC,Lee BI,Mathern GW,Moshé SL,Perucca E,Scheffer IE,Tomson T,Watanabe M,Wiebe S

    更新日期：2014-04-01 00:00:00

  • The effect of amygdala kindling on neuronal firing patterns in the lateral thalamus in the GAERS model of absence epilepsy.

    abstract：OBJECTIVE:The co-occurrence of absence and mesial temporal lobe epilepsy is rare in both humans and animal models. Consistent with this, rat models of absence epilepsy, including genetic absence epilepsy rats from Strasbourg (GAERS), are resistant to experimental temporal lobe epileptogenesis, in particular by amygdala...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/epi.12592

    authors： Carçak N,Zheng T,Ali I,Abdullah A,French C,Powell KL,Jones NC,van Raay L,Rind G,Onat F,O'Brien TJ

    更新日期：2014-05-01 00:00:00

  • Mortality in Dravet syndrome: search for risk factors in Japanese patients.

    abstract：:A questionnaire survey was conducted in Japan to investigate the causes and prevalence of death related to Dravet syndrome. The questionnaire was delivered to 246 hospitals at which physicians were treating childhood epilepsy to gain information about the total number of patients with Dravet syndrome and the prevalenc...

    journal_title：Epilepsia

    pub_type： 杂志文章,多中心研究

    doi：10.1111/j.1528-1167.2011.03002.x

    authors： Sakauchi M,Oguni H,Kato I,Osawa M,Hirose S,Kaneko S,Takahashi Y,Takayama R,Fujiwara T

    更新日期：2011-04-01 00:00:00

  • Interictal and ictal EEG activity in the basal ganglia: an SEEG study in patients with temporal lobe epilepsy.

    abstract：PURPOSE:The interictal and ictal EEG activity in the basal ganglia in patients with temporal lobe epilepsy were studied during invasive EEG monitoring. METHODS:Eight epilepsy surgery candidates, each with a proven mesiotemporal seizure-onset zone, participated in the study. We used two invasive EEG methods to determin...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1046/j.1528-1157.2002.28001.x

    authors： Rektor I,Kuba R,Brázdil M

    更新日期：2002-03-01 00:00:00

  • Comparison of 5 alpha-pregnan-3 alpha-ol-20-one and phenobarbital on cortical synaptic activation and inhibition studied in vitro.

    abstract：:The effects of 5 alpha-pregnan-3 alpha-ol-20-one (3 alpha-OH-DHP) and phenobarbital (PB) on synaptic excitation and inhibition in rat hippocampal slices in vitro were compared. Stimulations were made orthodromically and antidromically while we recorded extracellularly from the dendritic and the somatic layer of the CA...

    journal_title：Epilepsia

    pub_type： 杂志文章

    doi：10.1111/j.1528-1157.1993.tb02403.x

    authors： Taubøll E,Gjerstad L

    更新日期：1993-03-01 00:00:00