Abstract:
:This paper presents a comparison of three methods of parameter estimation in analysis of linkage between a quantitative trait locus (QTL) and a marker locus: maximum likelihood, mean square for trait cumulative distribution function, and method of moments, employing simulated backcross data. The sensitivity of estimates to violation of assumptions of normality and equal variances were also studied. Some measures of discrepancy between the trait distributions in the QTL groups are considered to evaluate the potential dependence of the resolution capacity of the QTL substitution effect with respect to trait mean value and variance.
journal_name
Biometricsjournal_title
Biometricsauthors
Korol AB,Ronin YI,Kirzhner VMsubject
Has Abstractpub_date
1996-06-01 00:00:00pages
426-41issue
2eissn
0006-341Xissn
1541-0420journal_volume
52pub_type
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