当前位置： SCI文献检索 > JOURNAL OF TRAVEL MEDICINE期刊下所有文献 > A dengue outbreak among camp participants in a Caribbean island, 1995.

A dengue outbreak among camp participants in a Caribbean island, 1995.

Abstract：

BACKGROUND:Dengue, a mosquito-transmitted viral disease, is a risk for visitors in tropical and subtropical areas. Several participants in a community-assistance program in Tortola, British Virgin Islands, in August, 1995, reported dengue-like symptoms either before or soon after leaving the island. METHODS:We conducted a retrospective cohort study to determine the extent of the outbreak, risk factors for illness, and the proportion of inapparent infections. Program participants were interviewed by telephone or mail, and asked to submit a serum sample for dengue diagnosis. A clinically-diagnosed case of dengue was defined as a person with fever and two or more of the following: headache, retro-orbital pain, myalgia, arthralgia, rash, or hemorrhagic manifestations. Serum specimens were tested for virus isolation, polymerase chain reaction (PCR), plaque-reduction neutralization (PRNT) or anti-dengue IgM and IgG antibody. RESULTS:Thirty-two (97%) of the 33 program participants responded; 21 of the 32 (66%) provided at least one serum sample for study. The median age was 17 years; 20 (62%) were women. Of 32 respondents, 22 (69%) met the clinical case definition for dengue: 15 of them (68%) had a positive IgM antibody response and 7 did not submit a serum sample. Dengue 1 virus (DEN-1) was identified by PCR in one case and all 11 positive PRNT results. No asymptomatic infections were identified. No respondent used effective mosquito repellent, and only 2 (6%) used bednets. CONCLUSIONS:A DEN-1 outbreak with a high attack rate (69%) occurred in a group of young short-term community aid workers. There were no asymptomatic infections documented. Participants' rare use of bednets or effective mosquito repellent highlights the importance of providing travelers to tropical areas with information about dengue fever and the recommended precautions to protect against infection.

journal_name

J Travel Med

journal_title

Journal of travel medicine

authors

Lyerla R,Rigau-Pérez JG,Vorndam AV,Reiter P,George AM,Potter IM,Gubler DJ

doi

10.2310/7060.2000.00022

subject

Has Abstract

pub_date

2000-03-01 00:00:00

pages

59-63

issue

eissn

1195-1982

issn

1708-8305

journal_volume

pub_type

杂志文章

在线工具

A dengue outbreak among camp participants in a Caribbean island, 1995.