Abstract:
BACKGROUND:Authorities have pledged to eliminate canine rabies by 2020 in Cambodia, a country with a very high rabies burden. Logistic and financial access to timely and adequate postexposure prophylaxis (PEP) is essential for preventing rabies in humans. METHODS:We undertook a survey of the few identified sites where PEP rabies vaccination and rabies immunoglobulin (RIG) are available in Cambodia. We examined the Rabies Prevention Center at Institut Pasteur du Cambodge (rpc@ipc) database and rpc@ipc order forms for 2012 to assess vaccine and RIG use. We conducted a rapid internet survey of centers that provide rabies vaccine and RIG in Cambodia, other than rpc@ipc. RESULTS:The cost of a full course of intramuscular or intradermal PEP in Cambodia, with and without RIG, was also estimated. Rabies vaccination is free of charge in one foundation hospital and is accessible for a fee at Institut Pasteur du Cambodge (IPC), some institutions, and some Cambodian private clinics. In 2012, 27,500 rabies vaccine doses (0.5 mL) and 591 equine RIG doses were used to provide intradermal PEP to 20,610 persons at rpc@ipc following animal bites. Outside of rpc@ipc, an estimated total of 53,400 vaccine doses and 200 RIG doses were used in Cambodia in 2012. The wholesale cost of full rabies PEP was estimated at 50% to 100% of a Cambodian farmer's monthly wage. CONCLUSIONS:Local populations and travelers cannot be sure to locally access adequate and timely PEP due to high costs and low access to RIG. Travelers to high-endemic areas such as Cambodia are strongly encouraged to undergo pre-exposure vaccination or seek expert advice, as per World Health Organization (WHO) recommendations. State-subsidized, pre-positioned stocks of human vaccine and RIG in bite management centers would extend the rabies prevention centers network. Support from Institut Pasteur du Cambodge for staff training, cold chain, and quality control would contribute to reducing the risk of rabies deaths in Cambodia.
journal_name
J Travel Medjournal_title
Journal of travel medicineauthors
Tarantola A,Ly S,In S,Ong S,Peng Y,Heng N,Buchy Pdoi
10.1111/jtm.12228subject
Has Abstractpub_date
2015-09-01 00:00:00pages
348-52issue
5eissn
1195-1982issn
1708-8305journal_volume
22pub_type
杂志文章abstract:BACKGROUND:Conventional treatment of imported malaria in Italy consists of quinine or mefloquine. Since beta-arthemeter is now available, an open-label pharmacodynamic analysis was performed in 73 adults with uncomplicated Plasmodium falciparum malaria. In vitro susceptibility to mefloquine and quinine was evaluated at...
journal_title:Journal of travel medicine
pub_type: 临床试验,杂志文章
doi:10.2310/7060.2005.12305
更新日期:2005-05-01 00:00:00
abstract::Canadians are increasingly travelling to areas that would necessitate a pre-travel consultation. Changes in professional regulations in Canada allow greater autonomy of nurses and pharmacists, resulting in shifts in provision of travel health services. We surveyed 824 Canadian travel clinics, 270 (33%) of whom respond...
journal_title:Journal of travel medicine
pub_type: 社论,评审
doi:10.1093/jtm/tay032
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Sexual behavior during travel has increasingly become a focus of travel medicine research. The perceived freedom when away from home can lead to increased casual sexual activities, often unprotected. Local sexual partners, particularly those who are in close contact with tourists due to their occupation, nee...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2007.00110.x
更新日期:2007-05-01 00:00:00
abstract::The diagnostic attitude of western physicians toward migrants' complaints is often an unstable balance between the obstinate search for exotic tropical diseases and the overappreciation of the cultural dimensions of symptoms. Such attitude may divert attention from organic diseases. The careful assessment of all level...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2009.00312.x
更新日期:2009-07-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2002.22460
更新日期:2002-01-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2006.00087.x
更新日期:2007-03-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2007.00142.x
更新日期:2007-09-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章,多中心研究
doi:10.1111/jtm.12179
更新日期:2015-05-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1093/jtm/taaa110
更新日期:2020-09-26 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1708-8305.1999.tb00838.x
更新日期:1999-06-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/jtm.12158
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Giardia infection is an ongoing problem in Tasmania and occurs throughout the state. It has been postulated that part of the problem is the reservoir of infection in native animals which is suggested to contribute to infections in humans. To date, however, no detailed study on the epidemiology of giardiasis ...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.1998.tb00485.x
更新日期:1998-09-01 00:00:00
abstract::A 35-year-old healthy Dutch woman went on a trek (Lang Tang) in Nepal up to an approximate altitude of about 3800 meters. She had no prior history of any medical problems except attacks of generalized epilepsy when she was 19 years old, which had been controlled with antiepileptic medications. She had had no attacks a...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.1998.tb00512.x
更新日期:1998-12-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/jtm.12136
更新日期:2014-11-01 00:00:00
abstract::A 34-year-old patient presented with giant, transient urticarial skin lesions and periorbital edema after a 3-month stay in DR Congo. Retrospective analysis of stored samples revealed that these signs were prodromal manifestations of acute hepatitis B infection. The hepatitis B infection was spontaneously cleared; the...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2011.00507.x
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:Prior to initiation of a program of registration, training, standards, and audit for yellow fever vaccination centers (YFVCs) in England, the National Travel Health Network and Centre (NaTHNaC) assessed the current practice and resource needs of these centers. METHODS:A questionnaire was sent to all YFVCs o...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2008.00217.x
更新日期:2008-09-01 00:00:00
abstract::Scrub typhus should be considered in any febrile patient presenting with a macular rash, a polyadenopathy, an eschar, or a history of environmental exposure in endemic areas. The differential diagnosis includes malaria, typhoid fever, leptospirosis, and arboviroses. Doxycycline 100 mg twice daily for 7 days should be ...
journal_title:Journal of travel medicine
pub_type: 杂志文章,评审
doi:10.1111/j.1708-8305.2007.00151.x
更新日期:2007-09-01 00:00:00
abstract:BACKGROUND:Several live attenuated vaccines against bacterial enteric pathogens have recently been licensed. These include the Salmonella typhi Ty21a typhoid vaccine (Vivotif Berna(R) Vaccine) and Vibrio cholerae CVD103-HgR cholera vaccine (Mutacol Berna(R) Vaccine). They comprise a unique class of biologics in which p...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.1998.tb00449.x
更新日期:1998-03-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2011.00582.x
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:Soldiers based in Townsville, Australia, returned from East Timor following peacekeeping operations during the wet season of 1999 to 2000. This represented the potential to import dengue virus into north Queensland, a dengue receptive area of Australia. This article seeks to outline the measures taken by the...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2002.24234
更新日期:2002-07-01 00:00:00
abstract:INTRODUCTION:Spain could be a potential area in Europe for the development and spread of emerging diseases from the tropics due to its geoclimatic characteristics, but there is little information on infectious diseases imported by travelers. The aim of this article was to analyze clinical-epidemiological characteristic...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2010.00433.x
更新日期:2010-09-01 00:00:00
abstract::Tropical sprue is a rare disease in travelers. Its etiology remains unclear. We report two cases of tropical sprue occurring in long-term residents in Nepal and Cameroon. In one case, Tropheryma whippelii, the agent of Whipple's disease, was identified. Many infectious agents have been suggested to be the etiological ...
journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2006.00038.x
更新日期:2006-05-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.2310/7060.2005.12611
更新日期:2005-11-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1093/jtm/taw062
更新日期:2016-09-13 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2009.00336.x
更新日期:2009-09-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2011.00578.x
更新日期:2012-01-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1111/j.1708-8305.2012.00627.x
更新日期:2012-07-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 杂志文章
doi:10.1093/jtm/tax001
更新日期:2017-07-01 00:00:00
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journal_title:Journal of travel medicine
pub_type: 临床试验,杂志文章
doi:10.2310/7060.2003.9359
更新日期:2003-11-01 00:00:00