A unique method for mutation analysis of tumor suppressor genes in colorectal carcinomas using a crypt isolation technique.

abstract：:Renal solitary fibrous tumors (SFTs) have been reported infrequently. We report a 76-year-old man with a left renal mass that had previously been shown radiographically to be stable, but was now growing. Grossly, the mass measured 12 cm, was poorly circumscribed, and invaded beyond the renal capsule. Approximately 10%...

journal_title：Archives of pathology & laboratory medicine

authors： Fine SW,McCarthy DM,Chan TY,Epstein JI,Argani P

更新日期：2006-06-01 00:00:00

abstract：:In 112 patients with mixed tumors of the salivary glands, 94 tumors were located in parotid glands, 11 in submandibular salivary glands, and 7 in monor palatal salivary glands. Capsular ingrowth, a characteristic growth pattern, may explain the frequency of multilobulation and capsular defects in these tumors, particu...

journal_title：Archives of pathology & laboratory medicine

authors： Naeim F,Forsberg MI,Waisman J,Coulson WF

更新日期：1976-05-01 00:00:00

abstract：OBJECTIVE:To better understand immunologic and pathophysiologic changes in the spleen in chronic immune thrombocytopenic purpura. DESIGN:We performed immunohistochemical studies on 12 spleens of patients with immune thrombocytopenic purpura. RESULTS:Four spleens had prominent hyperplastic secondary follicles in the w...

journal_title：Archives of pathology & laboratory medicine

authors： Jiang DY,Li CY

更新日期：1995-06-01 00:00:00

abstract：CONTEXT:Hyalinizing spindle cell tumor with giant rosettes is a recently described biphasic neoplasm of soft tissues that shares mesenchymal and neuroendocrine features. Its morphologic structure is distinctive, with the presence of hyalinized paucicellular foci that are termed rosettes. The cells around the latter dis...

journal_title：Archives of pathology & laboratory medicine

authors： Bejarano PA,Padhya TA,Smith R,Blough R,Devitt JJ,Gluckman JL

更新日期：2000-08-01 00:00:00

abstract：:An endobronchial papillary tumor in a 75-year-old reformed cigarette smoker exhibited the light microscopic features of a transitional cell neoplasm. The constituent cells showed cytologic features of malignancy; in addition, there were microfoci of mucosal invasion. Electron microscopy showed tonofilaments and numero...

journal_title：Archives of pathology & laboratory medicine

authors： Smith PS,McClure J

更新日期：1982-10-01 00:00:00

abstract：:Sensitivity, specificity, and predictive values are commonly used to report the performance characteristics of a diagnostic test. With tests that by their nature have more than two classes of results, calculation of sensitivity and specificity demands the combination of categories into two classes, leading to a loss o...

journal_title：Archives of pathology & laboratory medicine

authors： Giard RW,Hermans J

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVE:To design, develop, and implement a prototype medical event-reporting system for use in transfusion medicine to improve transfusion safety by studying incidents and errors. METHODS:The IDEALS concept of design was used to identify specifications for the event-reporting system, and a Delphi and subsequent nom...

journal_title：Archives of pathology & laboratory medicine

authors： Battles JB,Kaplan HS,Van der Schaaf TW,Shea CE

更新日期：1998-03-01 00:00:00

abstract：:Progressive sclerosing orbital pseudotumors are a subset of usually primary and localized idiopathic fibroinflammatory disorders. We report on a 66-year-old man who developed this condition along the facial tissue planes with extension into the orbit and preferential involvement of the periorbital membrane. Fibrocolla...

journal_title：Archives of pathology & laboratory medicine

authors： Mehta M,Jakobiec F,Fay A

更新日期：2009-08-01 00:00:00

abstract：CONTEXT:Mucin 4 (MUC4) is a high-molecular-weight membrane-bound glycoprotein that is expressed in the foregut before epithelial differentiation. It is found in normal adult airway epithelium, non-small cell lung carcinoma (NSCLC) and in other human malignancies independent of mucus secretion. Although its tissue distr...

journal_title：Archives of pathology & laboratory medicine

authors： Kwon KY,Ro JY,Singhal N,Killen DE,Sienko A,Allen TC,Zander DS,Barrios R,Haque A,Cagle PT

更新日期：2007-04-01 00:00:00

abstract：:Hepatoid carcinoma of the ovary (HCO) is a rare malignant tumor of uncertain histogenesis that was first described by Ishikura and Scully in the late 1980s. Unlike hepatoid yolk sac tumor (HYST), one of its main differential diagnoses, HCO usually presents in perimenopausal and postmenopausal women without gonadal dys...

journal_title：Archives of pathology & laboratory medicine

authors： Acosta AM,Pins MR

更新日期：2019-07-01 00:00:00

abstract：:We report the case of a primary breast rhabdomyosarcoma in a 51-year-old white woman. The tumor occupied the upper outer quadrant of the right breast. There was no association with the underlying pectoral muscle, and the patient was free of any other benign or malignant neoplastic processes outside the breast. Microsc...

journal_title：Archives of pathology & laboratory medicine

authors： Kyriazis AP,Kyriazis AA

更新日期：1998-08-01 00:00:00

abstract：:The human lymphocyte antigen (HLA) typing community was one of the early groups to adopt molecular testing. This action was borne out of the need to identify the many alleles of the highly polymorphic HLA system. Early paradigms used restriction fragment length polymorphism regimes, but the polymerase chain reaction m...

journal_title：Archives of pathology & laboratory medicine

authors： Gerlach JA

更新日期：2002-03-01 00:00:00

abstract：:We studied 16 cases of bile duct adenomas, lesions that are distinct from Meyenburg complex. The former lesion is made up of small tubular structures with little or no lumen, is usually single and subcapsular, and is unrelated to cystic disease. It must be differentiated from early carcinoma. Of the six cases encounte...

journal_title：Archives of pathology & laboratory medicine

authors： Govindarajan S,Peters RL

更新日期：1984-11-01 00:00:00

abstract：:We report two cases of primary cardiac lymphoma that developed in patients suffering from the acquired immunodeficiency syndrome. Both cases of lymphoma were histologically aggressive as generally observed in patients with the acquired immunodeficiency syndrome. The lymphoma cells in the center of a tumor nodule obtai...

journal_title：Archives of pathology & laboratory medicine

authors： Guarner J,Brynes RK,Chan WC,Birdsong G,Hertzler G

更新日期：1987-03-01 00:00:00

abstract：CONTEXT:- Colonic inertia is a debilitating form of primary chronic constipation with unknown etiology and diagnostic criteria, often requiring pancolectomy. We have occasionally observed massively enlarged submucosal ganglia containing at least 20 perikarya, in addition to previously described giant ganglia with great...

journal_title：Archives of pathology & laboratory medicine

authors： Naemi K,Stamos MJ,Wu ML

更新日期：2018-02-01 00:00:00

abstract：:Atherosclerosis can be defined as a disease process that occurs when the influx and deposition of cholesterol into the arterial wall exceed the egress of cholesterol from the arterial wall. This process is characterized by early deposition of cholesterol in and around arterial wall cells. The cholesterol is derived fr...

journal_title：Archives of pathology & laboratory medicine

authors： Mahley RW

更新日期：1983-08-01 00:00:00

abstract：CONTEXT:Because the consequences of making an interpretive error on a proficiency test are more severe than those made on an educational challenge, the same slide may exhibit different performance characteristics in the 2 different settings. OBJECTIVE:The results of the 2006 College of American Pathologists Gynecologi...

journal_title：Archives of pathology & laboratory medicine

authors： Hughes JH,Bentz JS,Fatheree L,Souers RJ,Wilbur DC,Cytopathology Resource Committee, College of American Pathologists.

更新日期：2009-02-01 00:00:00

abstract：CONTEXT:The laboratory test turnaround times (TATs) that exceed the expectations of clinicians who order those tests, the so-called outlier test reporting rates, may be responsible for perceptions of inadequate laboratory service. OBJECTIVE:To monitor outlier test reporting rates for emergency department stat potassiu...

journal_title：Archives of pathology & laboratory medicine

authors： Novis DA,Walsh MK,Dale JC,Howanitz PJ,College of American Pathologists Q-Tracks.

更新日期：2004-06-01 00:00:00

abstract：:Primary leiomyosarcoma of the pancreas is a rare tumor for which only 21 reports appear in the world literature. We describe an additional case of pancreatic leiomyosarcoma in a 76-year-old man, who complained of persistent high fever. Histologic examination revealed a pleomorphic spindle cell tumor. Reactivity for mu...

journal_title：Archives of pathology & laboratory medicine

authors： Nesi G,Pantalone D,Ragionieri I,Amorosi A

更新日期：2001-01-01 00:00:00

abstract：:Apoptosis and necrosis are two fundamental types of cell death. Current knowledge indicates that the key mechanism of apoptosis is endonuclease activation leading to internucleosomal double-stranded chromatin (DNA) breaks, whereas the key mechanism of necrosis is cell membrane damage. The initial alterations of cellul...

journal_title：Archives of pathology & laboratory medicine

authors： Buja LM,Eigenbrodt ML,Eigenbrodt EH

更新日期：1993-12-01 00:00:00

abstract：:Ciliated hepatic foregut cysts are rare congenital lesions derived from the embryologic foregut. They are considered benign, and a review of 64 published cases revealed no instances of malignant transformation. We report a case of squamous cell carcinoma arising in a ciliated hepatic foregut cyst in a 51-year-old man....

journal_title：Archives of pathology & laboratory medicine

authors： Vick DJ,Goodman ZD,Ishak KG

更新日期：1999-11-01 00:00:00

abstract：:A 67-year-old man, with multiple skin lesions that appeared over 2 years, had biopsies that disclosed granulomatous dermatitis with associated small yeasts. The urinary antigen test results were negative for Histoplasma infection; cultures from the biopsies did not grow any fungi or other potential pathogens. The ches...

journal_title：Archives of pathology & laboratory medicine

authors： Desai HB,Perkins PL,Procop GW

更新日期：2011-09-01 00:00:00

abstract：:A 50-year-old man presented with a lung mass in the left upper lobe, which was shown by electron microscopy to be a thymoma. There was no evidence of a mediastinal mass. The lymphocytes of the tumor reacted with monoclonal antibody T101, a pan T-cell marker, and with OKT8. B1 and B2 surface antigens characteristic of ...

journal_title：Archives of pathology & laboratory medicine

authors： Green WR,Pressoir R,Gumbs RV,Warner O,Naab T,Qayumi M

更新日期：1987-11-01 00:00:00

abstract：CONTEXT:The College of American Pathologists (CAP) Human Papillomavirus (High-Risk) Survey for Cytopathology and Other Laboratories (CHPV) meets the Clinical Laboratory Improvement Amendments of 1988 (CLIA '88) requirements for 5 proficiency testing challenges analyzed 3 times per year. This study reports laboratory pe...

journal_title：Archives of pathology & laboratory medicine

authors： Moriarty AT,Bentz JS,Winkler B,Fischer AH,Laucirica R,Souers RJ,Thomas N,Zhao C

更新日期：2013-05-01 00:00:00

abstract：:A T-cell immunoblastic lymphoma having plasmacytoid features that mimic B-cell immunoblastic lymphoma, is described. The lesion was composed of sheets of pleomorphic plasmacytoid cells that displayed a helper T-cell immunophenotype (Leu-1+, Leu-3+, Leu-4+, Leu-5+, Leu-9-, Leu-2-). Ultrastructural features were consist...

journal_title：Archives of pathology & laboratory medicine

authors： Swanson S,Innes DJ Jr,Frierson HF Jr,Hess CE

更新日期：1987-11-01 00:00:00

abstract：:Pulmonary adenocarcinoma is one of the most common types of lung cancer. Traditionally, adenocarcinomas have been divided based on their degree of resemblance to their parent tissues into 3 histopathologic types: well, moderately, and poorly differentiated. In the majority of cases, this schema is sufficient to catego...

journal_title：Archives of pathology & laboratory medicine

authors： Moran CA

更新日期：2006-07-01 00:00:00

abstract：:We report a case of hepatic inflammatory myofibroblastic tumor in a 26-year-old African American man who presented with right upper quadrant pain, weight loss, and fatigue during the previous year. Hepatomegaly was found on physical examination. Laboratory findings were significant for mild normocytic, normochromic an...

journal_title：Archives of pathology & laboratory medicine

authors： Solomon GJ,Kinkhabwala MM,Akhtar M

更新日期：2006-10-01 00:00:00

abstract：:Placental mesenchymal dysplasia is a rare placental lesion characterized by stem villous cystic dilation and vesicle formation, placentomegaly, and vascular abnormalities. It can be associated with growth restriction, stillbirth, Beckwith-Wiedemann syndrome, and some chromosomal abnormalities, and needs to be distingu...

journal_title：Archives of pathology & laboratory medicine

authors： Pawoo N,Heller DS

更新日期：2014-09-01 00:00:00

abstract：:An adenoma of type 2 pneumocytes in the periphery of the left lung was an incidental finding at the autopsy of a 28-year-old woman. Light microscopy revealed a predominantly papillary growth with oncocytic features. Ultrastructurally, multilaminated bodies and many mitochondria were found in the tumor cells and tubula...

journal_title：Archives of pathology & laboratory medicine

authors： Fine G,Chang CH

更新日期：1991-08-01 00:00:00

abstract：CONTEXT.—:Repair is a challenging diagnosis and a significant source of false-positive (FP) interpretations in cervical cytology. No large-scale study of performance of repair in the liquid-based era has been performed. OBJECTIVE.—:To evaluate the performance of repair in the College of American Pathologists Pap Educa...

journal_title：Archives of pathology & laboratory medicine

authors： Staats PN,Souers RJ,Nunez AL,Li Z,Kurtycz DFI,Goodrich K,Witt BL,Davey DD,Booth CN

更新日期：2019-11-22 00:00:00