Tumour cell dispersion by the ultrasonic aspirator during brain tumour resection.

Abstract:

:Ultrasonic aspirators are commonly used to resect brain tumours because they allow safe, rapid and accurate removal of diseased tissue. Since ultrasonic aspirators generate a spray of aerosolized irrigating fluid around the instrument tip, we questioned whether this spray might contain viable tumours cells that could contribute to intraoperative spread of tumour fragments. To test this hypothesis, we collected the spray produced during the resection of nine brain tumours with an ultrasonic aspirator and semi-quantitatively analysed it for tumour presence. The aerosolized irrigation fluid was found to contain intact tumour cells or clumps of tumour cells in all nine instances, and there was a trend of increasing tumour cell dispersion with increasing ultrasonic aspiration times. Further examination is required to determine if this intraoperative dispersion of apparently viable tumour fragments contributes to local neoplasm recurrence.

journal_name

Br J Neurosurg

authors

Preston JK,Masciopinto J,Salamat MS,Badie B

subject

Has Abstract

pub_date

1999-10-01 00:00:00

pages

486-9

issue

5

eissn

0268-8697

issn

1360-046X

journal_volume

13

pub_type

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