Abstract：
:The generation of phasic muscle activity during REM sleep is regulated by the brainstem. We proposed two sleep indices for phasic muscle activity during REM sleep, and examine their usefulness in assessing normal brainstem maturation and functional brainstem impairment during infancy. One - the dissociation index (DI) - seems to reflect maturation of the tonic inhibitory system functioning during REM sleep, and the other - % body movements in REMs bursts (%BMs-R) - to reflect that of the phasic one. In normal infants, DI showed a gradual, linear and significant increase with age, whereas %BMs-R showed a gradual and significant decrease with age. In infants with sudden infant death syndrome (SIDS) and one who had experienced apparent life-threatening events (ALTE), the DI values were lower than those in controls, although %BMs-R values were identical in the controls. In contrast, DI was variable in infants with West syndrome (WS), while %BMs-R exceeded normal values. The tonic inhibitory system seemed to be specifically involved in SIDS and ALTE, but the phasic inhibitory one in WS. Anatomical differences between these inhibitory systems are also discussed.
journal_name
J Sleep Resjournal_title
Journal of sleep researchauthors
Kohyama J,Shimohira M,Itoh M,Fukumizu M,Iwakawa Ydoi
10.1111/j.1365-2869.1993.tb00095.xsubject
Has Abstractpub_date
1993-12-01 00:00:00pages
241-249issue
4eissn
0962-1105issn
1365-2869pii
jsr002004241journal_volume
2pub_type
杂志文章abstract：:PAX6 gene mutations cause a variety of eye and central nervous system (CNS) abnormalities. Aniridia is often accompanied by CNS abnormalities such as pineal gland atrophy or hypoplasia, leading to disturbed circadian rhythm and sleep disorders. Less is known on the coincidence of narcolepsy in this patient group. We a...
journal_title：Journal of sleep research
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journal_title：Journal of sleep research
pub_type： 杂志文章,评审
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journal_title：Journal of sleep research
pub_type： 杂志文章
doi：10.1111/j.1365-2869.1993.tb00082.x
更新日期：1993-09-01 00:00:00
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journal_title：Journal of sleep research
pub_type： 杂志文章
doi：10.1111/j.1365-2869.1992.tb00048.x
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journal_title：Journal of sleep research
pub_type： 杂志文章
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pub_type： 杂志文章,评审
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journal_title：Journal of sleep research
pub_type： 杂志文章
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更新日期：1999-12-01 00:00:00
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journal_title：Journal of sleep research
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journal_title：Journal of sleep research
pub_type： 杂志文章,评审
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journal_title：Journal of sleep research
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journal_title：Journal of sleep research
pub_type： 杂志文章
doi：10.1111/jsr.12711
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journal_title：Journal of sleep research
pub_type： 杂志文章
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更新日期：2011-12-01 00:00:00
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journal_title：Journal of sleep research
pub_type： 杂志文章
doi：10.1111/j.1365-2869.1992.tb00025.x
更新日期：1992-06-01 00:00:00
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journal_title：Journal of sleep research
pub_type： 杂志文章
doi：10.1111/jsr.12549
更新日期：2017-12-01 00:00:00
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journal_title：Journal of sleep research
pub_type： 杂志文章,随机对照试验
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更新日期：2008-12-01 00:00:00
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journal_title：Journal of sleep research
pub_type： 杂志文章
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更新日期：2005-12-01 00:00:00
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journal_title：Journal of sleep research
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journal_title：Journal of sleep research
pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Journal of sleep research
pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2001-09-01 00:00:00
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journal_title：Journal of sleep research
pub_type： 杂志文章
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journal_title：Journal of sleep research
pub_type： 杂志文章
doi：10.1046/j.1365-2869.2002.00311.x
更新日期：2002-12-01 00:00:00
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journal_title：Journal of sleep research
pub_type： 杂志文章,实务指引
doi：10.1111/j.1365-2869.2006.00524.x
更新日期：2006-06-01 00:00:00
