Abstract：
:Despite the availability of safe and effective measles vaccines since 1963, measles still accounts for approximately 10% of global mortality from all causes among children aged less than 5 years, an estimated 36.5 million cases and 1 million deaths in 1996. Worldwide in 1996, routine coverage with 1 dose of measles vaccine was 81%, although the African Region of the World Health Organization reports the lowest coverage, at 56%, and the largest proportion of measles cases and deaths. There is an urgent need to strengthen measles control and explore the best ways to achieve that end, especially in areas such as West Africa. However, the data presented by Cisse et al. do not show that the 1995 outbreak of measles in Niakhar, Senegal, was due mainly to the waning of vaccine-induced immunity among school-aged children. Waning immunity therefore cannot be used to justify the introduction of a multidose vaccination schedule as a key strategy for improving measles control in developing countries. The authors explain the basis for their opinions. The immediate objective of any measles control program should be to provide a first dose of measles vaccine to unvaccinated children.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Strebel P,Guris D,Papania M,Cochi Sdoi
10.1093/oxfordjournals.aje.a009812subject
Has Abstractpub_date
1999-02-15 00:00:00pages
302-3issue
4eissn
0002-9262issn
1476-6256journal_volume
149pub_type
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更新日期：1982-08-01 00:00:00
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更新日期：2001-02-15 00:00:00
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