Abstract:
OBJECTIVE:To determine feasibility, validity, and cost effectiveness of the syndromic approach to male patients with urethral discharge in Bandung, Indonesia. METHODS:The WHO algorithm on urethral discharge with no microscopy available was evaluated. Patients presented with a complaint of urethral discharge and if discharge was confirmed the algorithm was applied. Treatment covered gonococcal and chlamydial infection (ciprofloxacin 500 mg single oral dose plus doxycycline 100 mg, twice daily orally for 7 days). The gold standard for validation was gonococcal culture and chlamydia antigen detection. RESULTS:140 male patients with a complaint of urethral discharge were enrolled; 119 had confirmed discharge and entered the decision tree: 107 were followed and 104 (97%) were clinically cured. Of the three patients with persistent discharge, one had a purulent urethral discharge, diagnosed as gonococcal urethritis and he was probably reinfected; two patients had a serous discharge and microbiological tests were negative. Overall, 106 out of 107 patients (99%) were microbiologically cured. Sensitivity of the algorithm is 100% and its positive predictive value (PPV) is 75% or 97% if validated against gold standard microbiological tests or Gram stain, respectively. Cost per patient is rupiah (Rp)5.894 ($US2.56) for the algorithm compared with Rp43.024 ($18.70) for full microbiological diagnosis. The cost estimate for an algorithm of urethral discharge with microscopy available is Rp6.432 ($2.80) CONCLUSION:The "symptom and sign" algorithm is fully adapted to the prevailing situation in primary healthcare settings, is acceptable to healthcare workers and patients (who are effectively treated at their first visit), is highly cost effective, is 100% sensitive (no false negatives, which is not the case with microbiological diagnosis), and has a high PPV, between 75% and 97%. It is an excellent patient management tool and a sound basis for partner notification so that it should have a major impact on STD/HIV control and prevention in both men and women.
journal_name
Sex Transm Infectjournal_title
Sexually transmitted infectionsauthors
Djajakusumah T,Sudigdoadi S,Keersmaekers K,Meheus Asubject
Has Abstractpub_date
1998-06-01 00:00:00pages
S29-33eissn
1368-4973issn
1472-3263journal_volume
74 Suppl 1pub_type
杂志文章abstract:OBJECTIVES:To determine the prevalence of identified STIs and recognised symptoms of STIs and their association with health status, substance use, and sexual risk behaviour in a sample of HIV seropositive men and women. METHODS:223 men, 112 women, and five transsexual people living with HIV infection completed confide...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.76.5.350
更新日期:2000-10-01 00:00:00
abstract:OBJECTIVE:To describe and compare sexual behaviour patterns in 1996 (before the explosion of the HIV epidemic in 2000) and 2006, and the correlates of high-risk sexual behaviour in Estonia. METHODS:Data on selected sexual behaviour characteristics were obtained by interviewing a probability sample of the adult populat...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2012-050506
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVES:We undertook a prospective evaluation of the Qualpro Syphicheck-WB rapid syphilis test to measure its diagnostic performance and utility as a point-of-care (POC) screening test among female sex workers (FSWs) in Bangalore, India. METHODS:From August 2008 to May 2009, FSWs without a laboratory-confirmed hist...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究
doi:10.1136/sti.2009.038778
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVES:To design and implement an HIV surveillance system using periodic cross sectional prevalence surveys in National Guard recruits of the Republic of Cyprus. METHODS:HIV infection surveillance used unlinked anonymous screening (UAS) methodology, which tested residual blood originally collected for other purpos...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.78.1.50
更新日期:2002-02-01 00:00:00
abstract:OBJECTIVE:To determine the seroprevalence rate of syphilis among pregnant women attending the antenatal clinics of a teaching and a state specialist hospital in Nigeria, in order to ascertain whether maternal screening should be incorporated into routine antenatal care of our hospitals. METHODS:A screening for syphili...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2006.023416
更新日期:2007-08-01 00:00:00
abstract:OBJECTIVES:To describe the seroepidemiology of herpes simplex virus (HSV) types 1 and 2 in the general populations of eight European countries to better understand recent reported changes in disease epidemiology. METHODS:Belgium, Bulgaria, Czech Republic, England and Wales, Finland, Germany, Netherlands, and Slovenia ...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究
doi:10.1136/sti.2003.005850
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVE:Three decades into the HIV epidemic and with the advancement of HIV treatments, condom and non-condom-based anal intercourse among gay men in resource-rich countries needs to be re-assessed. METHODS:The proportions of men engaging in a range of anal intercourse practices were estimated from the ongoing cross...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2011-050041
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVES:To measure the prevalence of HSV-2 antibodies in a birth cohort of 21 year old New Zealanders from whom detailed sexual histories had been obtained, and to assess the potential for HSV-2 serology in characterising a young adult population's risk for sexually transmitted diseases (STD). METHODS:Sera from 784...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.74.3.216
更新日期:1998-06-01 00:00:00
abstract:OBJECTIVES:Young women in sub-Saharan Africa are at high risk of STIs and unintended pregnancies, yet hormonal contraceptive (HC) use may affect STI risk. We compared the influence of three HCs on the incidence and prevalence of STIs and bacterial vaginosis (BV) in South African adolescents. METHODS:One hundred and th...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2020-054483
更新日期:2020-09-28 00:00:00
abstract:OBJECTIVES:Geosocial networking application specific to men who have sex with men (MSM) (gay app) has revolutionised the social networking of MSM globally, much concern was raised over its linkage to HIV/syphilis risk. This study sought to examine the association between use of gay app and sexual behaviours and HIV/syp...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2018-053902
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:The objective of this study was to compare the costs and outcomes of two sexually transmitted infection (STI) screening interventions targeted at men in football club settings in England, including screening promoted by team captains. METHODS:A comparison of costs and outcomes was undertaken alongside a pil...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,随机对照试验
doi:10.1136/sextrans-2014-051715
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence and clinical features of Trichomonas vaginalis (TV) infection in men. METHODS:Men attending a public STD clinic in Baltimore, Maryland, were evaluated between March and July 2000. Clinicians recorded a standardised history and clinical examination. Urethral swab specimens were col...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.79.2.151
更新日期:2003-04-01 00:00:00
abstract:BACKGROUND:Accession of 10 Central and Eastern European (CEE) countries to the E.U. resulted in the largest migratory influx in peacetime British history. No information exists on the sexual behaviour of CEE migrants within the U.K. The aim of this study was to assess the sexual lifestyles and health service needs of t...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2010.047209
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:The Sydney Sexual Health Centre in Australia uses a proforma tool to screen all new female clients for recent physical intimate partner violence (IPV). This study describes the prevalence and associations of recent physical IPV among women attending a sexual health clinic. METHOD:The clinic database was use...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2010.043109
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVES:To inform control strategies undertaken as part of an outbreak of Shigella flexneri 3a among men who have sex with men (MSM). METHODS:All men aged ≥18 years diagnosed with S flexneri 3a between October 2012 and May 2013 were invited to participate. Semistructured in-depth quantitative interviews were conduc...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2015-052014
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVES:Bacterial vaginosis (BV) increases women's susceptibility to sexually transmitted infections (STIs) and HIV and may partly explain the high incidence of STI/HIV among girls and young women in East and southern Africa. The objectives of this study were to investigate the association between BV and sexual debu...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2018-053680
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVE:To estimate the predictive values for HIV infection of diagnosis of oral manifestations of the infection. METHOD:Prevalence of oral manifestations was compared in cross sectional blinded clinical examinations of homosexual men attending a genitourinary medicine clinic. Data were extrapolated to populations i...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.74.5.345
更新日期:1998-10-01 00:00:00
abstract:OBJECTIVE:Comprehensive data on Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections to guide screening services among transgender women (TGW) are limited. We studied the burden of CT/NG infections in pharyngeal, rectal and urethral sites of Thai TGW and determined missed CT/NG diagnoses if selected sit...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2018-053835
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:Millions of patients are prescribed drugs for sexually transmitted infections (STIs) in developing countries each year, yet the treatment effect of these prescriptions is largely unknown. OBJECTIVES:To determine if the prescribing of erythromycin and ceftriaxone to pregnant women with STI symptoms leads to ...
journal_title:Sexually transmitted infections
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1136/sti.2003.007757
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVE:To examine the frequency of three sexual behaviours from the most active to the least active members of the population in various subpopulations using measures of inequality. METHODS:Data from a US national probability sample of the population aged 15-44 years (National Survey of Family Growth) were used. Gi...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.2010.042283
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVES:To assess whether a previously established low sexually transmitted infection/HIV risk in prostitutes in London has been sustained, and to measure other occupational risks, including mortality. DESIGN:9 year prospective study in west London. SUBJECTS:402 prostitutes recruited from 1985 to 1991, 320 were fo...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.75.5.340
更新日期:1999-10-01 00:00:00
abstract:BACKGROUND:Little is known about infection rates for human immunodeficiency virus (HIV) and other diseases that can be transmitted sexually in Bangladeshi women who may be at intermediate levels of risk--that is, women who are not commercial sex workers (CSWs) but whose sexual contacts may include men at high risk for ...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sti.77.5.344
更新日期:2001-10-01 00:00:00
abstract:OBJECTIVES:In addition to researcher-designed sampling biases, population-representative surveys for biomarker measurement of STIs often have substantial missingness due to non-contact, non-consent and other study-implementation issues. STI prevalence estimates may be biased if this missingness is related to STI risk. ...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2019-054342
更新日期:2020-11-01 00:00:00
abstract::Recent advances in genetic characterisation of Trichomonas vaginalis isolates show that the extensive clinical variability in trichomoniasis and its disease sequelae are matched by significant genetic diversity in the organism itself, suggesting a connection between the genetic identity of isolates and their clinical ...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,评审
doi:10.1136/sextrans-2013-051098
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Although physician recommendation is one of the strongest predictors of human papillomavirus (HPV) vaccination, it is unclear for whom physicians are recommending the vaccine. To help guide intervention efforts, this study investigated predictors of participant-reported physician recommendation for HPV vacci...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2015-052088
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVES:To assess the feasibility and utility of sentinel laboratory surveillance of HIV testing as a tool for understanding patterns and trends in HIV testing in a range of healthcare services. METHODS:Data on all anti-HIV antibody tests carried out by the Leeds Teaching Hospital Trust laboratory over a 12-month p...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究
doi:10.1136/sti.2009.041293
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:To explore ideas of truck drivers and villagers from rural Tanzania about heterosexual anal sex (HAS) and the associated health risks. METHODS:Qualitative study using 8 in-depth interviews (IDIs) and 2 focus group discussions (FGDs) with truck drivers and 16 IDIs and 4 FGDs with villagers from the Morogoro r...
journal_title:Sexually transmitted infections
pub_type: 杂志文章
doi:10.1136/sextrans-2015-052055
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVES:To assess HIV and syphilis prevalence, HIV-related behaviours and testing for HIV in female sex workers (FSW) in Sudan. DESIGN:Bio-behavioural surveys using respondent-driven sampling were carried out among FSW in the capital cities of 14 states in Sudan in 2011-2012. HIV and syphilis testing was done by ra...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究
doi:10.1136/sextrans-2013-051097
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Genital herpes (GH) is a common sexually transmitted infection. Novel tools for the control of GH (for example, tests and vaccines) are emerging, but optimal assessment of the cost effectiveness of such interventions requires scaled, preference based estimates of the impact of GH on health related quality of...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究
doi:10.1136/sti.2004.011619
更新日期:2005-06-01 00:00:00
abstract:OBJECTIVE:To compare and contrast attitudes and behaviours of family doctors and patients with regard to genital herpes and its management. METHODS:Family doctors and infected patients were surveyed online to explore disease importance/seriousness, emotional impact, transmission and treatment. The study received ethic...
journal_title:Sexually transmitted infections
pub_type: 杂志文章,多中心研究
doi:10.1136/sti.2007.027631
更新日期:2008-02-01 00:00:00