Herpes simplex type 2 infection in a cohort aged 21 years.

Abstract:

OBJECTIVES:To measure the prevalence of HSV-2 antibodies in a birth cohort of 21 year old New Zealanders from whom detailed sexual histories had been obtained, and to assess the potential for HSV-2 serology in characterising a young adult population's risk for sexually transmitted diseases (STD). METHODS:Sera from 784 cohort members were tested using an indirect IgG enzyme linked immunoassay specific to the HSV-2 glycoprotein G. Positive results were confirmed by western blot. RESULTS:In all, 27 subjects were seropositive for HSV-2 (3.4%), only seven of whom gave a history of genital herpes (26%). Risk among females increased with lifetime number of partners, while risk for males increased with having a first partner who was aged 16 years or under. CONCLUSIONS:The seroprevalence of HSV-2 infection in this cohort was low, but similar to that seen in several other populations in this age group. HSV-2 seropositivity did not appear to be a sensitive marker for high risk sexual activity in this young population. This may be because a critical mass of HSV-2 carriers has not accumulated among potential partners by age 21 years.

journal_name

Sex Transm Infect

authors

Eberhart-Phillips J,Dickson NP,Paul C,Fawcett JP,Holland D,Taylor J,Cunningham AL

doi

10.1136/sti.74.3.216

subject

Has Abstract

pub_date

1998-06-01 00:00:00

pages

216-8

issue

3

eissn

1368-4973

issn

1472-3263

journal_volume

74

pub_type

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