Apoptosis following gamma knife radiosurgery in a case of acoustic schwannoma.

Abstract:

:A 25-year-old woman with a large acoustic schwannoma underwent surgical excision 18 months after Gamma Knife radiosurgery because of transient expansion of the tumor causing ataxia. Histopathologial investigation by the TUNEL method revealed the presence of some apoptotic cells. The findings were compared with findings from a control group of 7 operated cases where radiosurgery had not been used. There was no apoptosis found in any of these cases. In addition, another case which resulted in a regrowing tumor following Gamma Knife treatment also showed no apoptosis. These findings suggest apoptosis may be a possible mechanism in reducing tumor size following Gamma Knife radiosurgery.

authors

Fukuoka S,Oka K,Seo Y,Tokanoshi M,Sumi Y,Nakamura H,Nakamura J,Ikawa F

doi

10.1159/000056411

subject

Has Abstract

pub_date

1998-10-01 00:00:00

pages

88-94

eissn

1011-6125

issn

1423-0372

pii

sfn0a088

journal_volume

70 Suppl 1

pub_type

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