Stereotactic radiosurgery as a salvage treatment for recurrent epipharyngeal carcinoma.

Abstract:

:Fourteen patients with recurrent epipharyngeal carcinoma (EPC) were treated by gamma knife stereotactic radiosurgery. The tumor volume ranged from 0.3 to 80 ml (median 18.9 ml). Treatment was done with a tumor margin dose of 10-27 Gy (median 15 Gy). The median follow-up period was 15 months (range 2-47 months). Ten patients were alive and 4 were dead at the end of the follow-up period. In 6 patients (43%), the tumor disappeared or decreased in size until the end of the follow-up period. In 2 (14%), the tumor remained unchanged in size. In 6 (43%), the tumor showed regression initially but was enlarged later. A second radiosurgery was performed in 4 of those 6 cases and the tumor decreased in size again in 3 of them. Thus, the overall control rate of local tumor was 79% (11/14). In selected patients with recurrent EPC, stereotactic radiosurgery can be considered as a salvage treatment producing local control.

authors

Oda K,Mori Y,Kobayashi T,Kida Y,Yokoi H,Shibamoto Y,Yoshida J

doi

10.1159/000094461

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

103-8

issue

2-3

eissn

1011-6125

issn

1423-0372

pii

94461

journal_volume

84

pub_type

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