Abstract:
:The aim of the study was to investigate if laser Doppler perfusion monitoring (LDPM) can be used in order to differentiate between gray and white matter and to what extent microvascular perfusion can be recorded in the deep brain structures during stereotactic neurosurgery. An optical probe constructed to fit in the Leksell Stereotactic System was used for measurements along the trajectory and in the targets (globus pallidus internus, subthalamic nucleus, zona incerta, thalamus) during the implantation of deep brain stimulation leads (n = 22). The total backscattered light intensity (TLI) reflecting the grayness of the tissue, and the microvascular perfusion were captured at 128 sites. Heartbeat-synchronized pulsations were found at all perfusion recordings. In 6 sites the perfusion was more than 6 times higher than the closest neighbor indicating a possible small vessel structure. TLI was significantly higher (p < 0.005) and the perfusion significantly lower (p < 0.005) in positions identified as white matter in the respective MRI batch. The measurements imply that LDPM has the potential to be used as an intracerebral guidance tool.
journal_name
Stereotact Funct Neurosurgjournal_title
Stereotactic and functional neurosurgeryauthors
Wårdell K,Blomstedt P,Richter J,Antonsson J,Eriksson O,Zsigmond P,Bergenheim AT,Hariz MIdoi
10.1159/000107360subject
Has Abstractpub_date
2007-01-01 00:00:00pages
279-86issue
6eissn
1011-6125issn
1423-0372pii
000107360journal_volume
85pub_type
临床试验,杂志文章abstract::Transient postoperative confusion (POC) occurs in 5-25% of patients following bilateral subthalamic nucleus stimulation. We retrospectively reviewed data on 96 patients who underwent bilateral subthalamic nucleus deep brain stimulation for Parkinson's disease. Nine percent of patients developed POC. There was no signi...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000086676
更新日期:2005-01-01 00:00:00
abstract::This is a report on a patient with intractable 'primary' generalized seizures and typical spike-wave EEG patterns, in whom an unexpected temporal lobe astrocytoma was detected by MRI studies. Clinical and electrophysiological studies were performed before and after surgical excision of the tumor and apical temporal lo...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000098729
更新日期:1995-01-01 00:00:00
abstract::The underlying electrophysiologic abnormality in patients with chronic pain syndrome is demonstrated in 2 patients whose pain and associated symptoms were incapacitating. Mechanical perturbation evoked discharges most easily at the mesodiencephalic junction. Discharging tissue at that level appears to be oriented in b...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099499
更新日期:1989-01-01 00:00:00
abstract::Craniotomy using stereotactic techniques has the potential to improve the extent of tumor resection and to reduce wound and neurologic morbidity. Most reports of stereotaxy-assisted craniotomy (SC) for tumor resection have focused on techniques using sophisticated computer hardware and volumetric software. Results of ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 临床试验,杂志文章
doi:10.1159/000100625
更新日期:1993-01-01 00:00:00
abstract::Between 1985 and 1997, 563 therapeutic craniotomies were performed: 311 anterior temporal (ATL) and 158 extramesial temporal (XMT) resections, 67 callosotomies, 20 hemispherectomies and 7 multiple subpial transections. Sixty-seven percent of nonlesional ATL cases were seizure free (SF), and 76% of nonlesional ATL case...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000029763
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:A patient controller (PC) is an optional device for patients with deep brain stimulation (DBS) to have limited control of their stimulator system. OBJECTIVES:We investigated the impact of a PC on DBS safety, most notably the handling/prevention of unexpected DBS failure in patients with Parkinson's disease ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000329361
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Balloon compression of the gasserian ganglion has been a well-established percutaneous treatment of trigeminal neuralgia since the 1980s. However, puncture of the foramen ovale by conventional single-plane fluoroscopy can be difficult in cases of local anatomic abnormalities. CASE PRESENTATION:We present th...
journal_title:Stereotactic and functional neurosurgery
pub_type:
doi:10.1159/000509821
更新日期:2020-09-16 00:00:00
abstract:BACKGROUND:Microvascular decompression (MVD) has been the right choice for glossopharyngeal neuralgia (GPN) patients. However, whether glossopharyngeal/vagal nerve root rhizotomy should be combined with MVD is still controversial. OBJECTIVE:To evaluate whether glossopharyngeal/vagal nerve root rhizotomy during MVD is ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000505712
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:The results from thalamic deep brain stimulation (DBS) for atypical tremor syndromes including tremor from multiple sclerosis (MS) and stroke are often disappointing. Three recent case reports have suggested that simultaneous stimulation of multiple thalamic targets can result in sustained improvement in suc...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099072
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVES:Interpreting the postoperative electroencephalographic (EEG) driving response (DR) as an indicator of electrode placement within the thalamic nucleus in deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) for refractory epilepsy is controversial. MATERIALS AND METHODS:We retrospective...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000449012
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:Deep brain stimulation (DBS) of the internal segment of the globus pallidus (GPi) is an alternative therapy in ameliorating the clinical symptoms of primary Meige syndrome. Nevertheless, proof of its efficacy and safety is insufficient due to several case reports and small-sample clinical studies. This study ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000504861
更新日期:2019-01-01 00:00:00
abstract::We describe the Zamorano-Dujovny localizing unit which consists of a ring-shaped headholder held on the patient's head by three or four variably placed fixation pins, thereby avoiding interference with the flap sites or craniotomy. The base ring is mounted intraoperatively on a special adapter that allows any patient ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000100290
更新日期:1994-01-01 00:00:00
abstract::To elucidate the radiobiological effect of Gamma Knife radiosurgery on brain tumors, we performed a histological study on nine cases. In two, the material was obtained at autopsy and in seven following surgery. In the central region of the radiation field, destructive changes occurred both in tumor cells and in vessel...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099695
更新日期:1996-01-01 00:00:00
abstract::The objective of this case report is to demonstrate that a benign tumour arising solely from the olfactory bulb can act as a primary epileptic focus and to illustrate the difficulty in making a preoperative diagnosis of pathological lesions in this area. The case of a 29-year-old male with intractable epilepsy is pres...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000070104
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:Stereotactic biopsies are subject to sampling errors (essentially due to target selection). The presence of contrast enhancement is not a reliable marker of malignancy. The goal of the present study was to determine whether perfusion-weighted imaging can improve target selection in stereotactic biopsies. MET...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000338092
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION:The primary goal of stereotactic systems in deep brain stimulation (DBS) surgery is accurate delivery of a DBS lead to a target identified on imaging. Thus, it is critical to understand the accuracy of the stereotactic systems and the factors which may be associated with a decrease in accuracy. METHODS:Ni...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000316761
更新日期:2010-01-01 00:00:00
abstract::Computerized brain atlas is a new application area in the practical use of stereotactic neurosurgery. Our approach provides a solution for the straightforward definition of a coordinate system (CA-CP), localization of the selected target point, trepanation points and trajectory transformation of the stereotactic elect...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099858
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Few multiple case studies of the effects of deep brain stimulation for camptocormia associated with Parkinson's disease have been reported. Although deep brain stimulation was in some cases not effective against camptocormia, it is unclear in which types of patients it was effective in treating camptocormia....
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000324907
更新日期:2011-01-01 00:00:00
abstract::In this study, we investigated the efficacy of brachytherapy in the treatment of 138 patients with intracranial neoplasms of the CNS. Of the total number of patients, 50 presented with glioblastoma multiforme, 45 presented with low-grade glioma, 19 presented with anaplastic astrocytoma, 23 presented with metastases an...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000075100
更新日期:2003-01-01 00:00:00
abstract::A Leksell Gamma Unit was commissioned and a Lars Leksell Center for Radiosurgery was established at the University of Virginia Health Sciences Center in March 1989. At that time a formal quality assurance program designed for the Leksell Gamma Unit was put into effect. This paper will review the components of suggeste...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099561
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND/AIMS:Parkinson's disease (PD) is an idiopathic progressive neurological disorder. Improvement in motor function of PD patients has been established with subthalamic nucleus (STN) deep brain stimulation (DBS). While variations in DBS settings (i.e. amplitude, frequency and pulse width) on motor function have ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 临床试验,杂志文章
doi:10.1159/000163554
更新日期:2008-01-01 00:00:00
abstract::We present a system for surgical navigation using stereo overlays in the operating microscope aligned to the operative scene. This augmented reality system provides 3D information about nearby structures and offers a significant advancement over pointer-based guidance, which provides only the location of one point and...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000029708
更新日期:1999-01-01 00:00:00
abstract::Stereotactic guidance is useful for planning an accurate trajectory to the third ventricle. A guiding block with a ball joint was developed for frame-based endoscopy and adaptors for arm-based and armless navigation systems. Between 1992 and 1996, 52 patients were operated on endoscopically in the third ventricle unde...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099907
更新日期:1997-01-01 00:00:00
abstract::The first Gamma Knife was installed in Stockholm in 1968 after nearly two decades of development. Following the opening of the Gamma Knife facility in Pittsburgh in 1987, radiosurgery has seen an explosive expansion. Along with this expansion there has been a development of alternative technologies, of which the most ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Posttraumatic stress disorder (PTSD) is a prevalent and highly disabling psychiatric disorder that is notoriously difficult to treat. At some point in their lifetimes, 5-8% of men, 10-14% of women, and up to a quarter of combat veterans carry this diagnosis. Despite pharmacological and behavioral therapies, up to 30% ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000343148
更新日期:2013-01-01 00:00:00
abstract:PURPOSE:Gamma knife (GK) radiosurgery for trigeminal neuralgia (TN) has been effective in 50-80% of cases when using a single 4-mm collimator and a maximum dose of 60-90 Gy. Attempting to improve the response rate by increasing the dose may lead to increased risk of facial numbness or disturbed sensation. Combined use ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000076661
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Writer's cramp is a specific movement disorder with hand muscle cramps in writing, being classified into focal and action-specific dystonia. Stereotactic surgery, such as thalamotomy and deep brain stimulation (DBS), has been reported for writer's cramp; however, the number of reported cases is still scarce ...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000366004
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Hypothalamic hamartomas are associated with precocious puberty and chronic epilepsy characterized by gelastic seizures. The seizure disorder is usually refractory to most antiepileptic drugs. Gamma knife surgery has emerged as an alternative to microsurgical removal or radiofrequency ablation to improve seiz...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000094036
更新日期:2006-01-01 00:00:00
abstract::The authors assessed whether gamma knife radiosurgery is effective for patients with acromegaly where the pituitary tumors invaded the cavernous sinus. Radiosurgery was performed on 9 patients (average of 20 Gy to the tumor margin), 8 of whom had already undergone transsphenoidal surgery and/or craniotomy with occasio...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000066721
更新日期:2001-01-01 00:00:00
abstract::The author has performed 108 stereotactic thalamotomies using MRI (MGSTs) without ventriculography in 77 cerebral palsy (CP) patients with dyskinesia(s) from January 1992 to January 1997. The clinical results were verified in terms of improvement of major preoperative symptom and patient's (or relative's) satisfaction...
journal_title:Stereotactic and functional neurosurgery
pub_type: 杂志文章
doi:10.1159/000099891
更新日期:1997-01-01 00:00:00