Quantification of post-concussion symptoms 3 months after minor head injury in 100 consecutive patients.

Abstract:

:Post-concussion symptoms (PCS) (such as headaches, irritability, anxiety, dizziness, fatigue and impaired concentration) are frequently experienced by patients who have sustained a minor head injury (MHI). The post-concussion syndrome has been defined as a clinical state where 3 or more symptoms persist for more than 3 months. This report focuses on the quantification of PCS according to the Rivermead Postconcussion Symptoms Questionnaire (RPQ). We studied 100 consecutive patients with MHI and normal computed tomography of the brain. At 3 months after injury, 62% reported the presence of one or more symptoms, and 40% fulfilled the diagnostic criteria for post-concussion syndrome. Patients with post-concussion syndrome had significantly (P < 0.001) higher RPQ scores (mean 19.1, SD 11.9) than those without (mean 1.2, SD 1.8). Patients on sick leave owing to the injury reported significantly (P = 0.05) higher RPQ scores (mean 10.3, SD 13.2) than those not on sick leave (mean 5.5, SD 8.6). We observed no association between age, gender, cause of injury, severity of injury, duration of amnesia and RPQ score. RPQ score provides useful information about the severity of PCS regardless of whether the diagnostic criteria for the post-concussion syndrome are met or not.

journal_name

J Neurol

journal_title

Journal of neurology

authors

Ingebrigtsen T,Waterloo K,Marup-Jensen S,Attner E,Romner B

doi

10.1007/s004150050254

subject

Has Abstract

pub_date

1998-09-01 00:00:00

pages

609-12

issue

9

eissn

0340-5354

issn

1432-1459

journal_volume

245

pub_type

临床试验,杂志文章
  • New insights into Parkinson's disease.

    abstract::Parkinson's disease (PD) is the most common neurodegenerative movement disorder. Recent advances in genetics and pathophysiology have led to new insights into the pathogenesis of PD. Ten loci have been linked to hereditary PD. Mutations in alpha-synuclein and ubiquitin carboxy hydrolase L1 (UchL1) cause autosomal domi...

    journal_title:Journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s00415-003-1304-9

    authors: Chung KK,Dawson VL,Dawson TM

    更新日期:2003-10-01 00:00:00

  • Clinical experience with high-dose idebenone in Friedreich ataxia.

    abstract::Several reports in the literature describe the effects of low-dose (5 mg/kg/day) idebenone in significantly reducing cardiac hypertrophy in patients with Friedreich ataxia. However, the effects of idebenone on neurological function have not been reliably determined in these studies; when neurological parameters were r...

    journal_title:Journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s00415-009-1008-x

    authors: Schulz JB,Di Prospero NA,Fischbeck K

    更新日期:2009-03-01 00:00:00

  • Utility of a next-generation sequencing-based gene panel investigation in German patients with genetically unclassified limb-girdle muscular dystrophy.

    abstract::Limb-girdle muscular dystrophies (LGMDs) are genetically heterogeneous and the diagnostic work-up including conventional genetic testing using Sanger sequencing remains complex and often unsatisfactory. We performed targeted sequencing of 23 LGMD-related genes and 15 genes in which alterations result in a similar phen...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-016-8036-0

    authors: Kuhn M,Gläser D,Joshi PR,Zierz S,Wenninger S,Schoser B,Deschauer M

    更新日期:2016-04-01 00:00:00

  • Pretreatment cerebral microbleeds and symptomatic intracerebral hemorrhage post-thrombolysis: a systematic review and meta-analysis.

    abstract:BACKGROUND AND PURPOSE:Cerebral microbleeds (CMBs) are a possible predictor of symptomatic intracranial hemorrhage (sICH) and poor function outcome (PFO). We aimed to investigate the presence of CMBs on increased incidence of sICH and PFO in acute ischemic stroke patients receiving intravenous thrombolysis (IVT) treatm...

    journal_title:Journal of neurology

    pub_type: 杂志文章,meta分析

    doi:10.1007/s00415-018-9156-5

    authors: Yan J,Qiu J,Wu X,Ge Y,Wang J,Wang Y

    更新日期:2020-02-01 00:00:00

  • A new mutation in GJC2 associated with subclinical leukodystrophy.

    abstract::Recessive mutations in GJC2, the gene-encoding connexin 47 (Cx47), cause Pelizaeus-Merzbacher-like disease type 1, a severe dysmyelinating disorder. One recessive mutation (p.Ile33Met) has been associated with a much milder phenotype--hereditary spastic paraplegia type 44. Here, we present evidence that a novel Arg98L...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-014-7429-1

    authors: Abrams CK,Scherer SS,Flores-Obando R,Freidin MM,Wong S,Lamantea E,Farina L,Scaioli V,Pareyson D,Salsano E

    更新日期:2014-10-01 00:00:00

  • New evidence for involvement of ESR1 gene in susceptibility to Chinese migraine.

    abstract::Migraine is a common and disabling nervous system disease with a significant genetic predisposition. The sex hormones play an important role in the pathogenesis of migraine. However, the conclusions of the previous genetic relation studies are conflicting. The aim of this study is to determine whether variants in gene...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-016-8321-y

    authors: An X,Fang J,Lin Q,Lu C,Ma Q,Qu H

    更新日期:2017-01-01 00:00:00

  • Recent developments in multiple system atrophy.

    abstract::Multiple system atrophy (MSA) is a rare late onset neurodegenerative disorder which presents with autonomic failure and a complicated motor syndrome including atypical parkinsonism, ataxia and pyramidal signs. MSA is a glial alpha-synucleinopathy with rapid progression and currently poor therapeutic management. This p...

    journal_title:Journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s00415-009-5173-8

    authors: Wenning GK,Stefanova N

    更新日期:2009-11-01 00:00:00

  • Optic neuritis presenting with amaurosis fugax.

    abstract::Optic neuritis usually presents with rapid and gradual loss of vision that is either complete or incomplete, and typically associated with retro-orbital pain. To our knowledge there have been no documented reports of optic neuritis presenting with multiple episodes of amaurosis fugax, the sudden and transient loss of ...

    journal_title:Journal of neurology

    pub_type: 信件

    doi:10.1007/s00415-009-5302-4

    authors: Awad AM,Estephan B,Warnack W,Stüve O

    更新日期:2009-12-01 00:00:00

  • Prognostic criteria in an epidemiological group of patients with multiple sclerosis: an exploratory study.

    abstract::Demographic and clinical features and data on medical history and prior environmental exposure collected during an epidemiological long-term study of multiple sclerosis (MS) were tested for their possible prognostic value. Fifty-two benign MS patients were compared with 29 patients having a malignant course. A primary...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00862981

    authors: Lauer K,Firnhaber W

    更新日期:1992-02-01 00:00:00

  • Cognitive and affective disturbances in multiple sclerosis.

    abstract::The emotional and relationship problems associated with MS have not always been fully appreciated by the medical profession, which has tended to concentrate on the physical aspects of this disease. Yet the psychological problems of MS often cause more suffering than physical effects. ...

    journal_title:Journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s004150170223

    authors: Kesselring J,Klement U

    更新日期:2001-03-01 00:00:00

  • Medial temporal lobe epilepsy associated with hippocampal sclerosis is a distinctive syndrome.

    abstract::Epileptic syndromes are distinctive disorders with specific features, which when taken together, permit a specific diagnosis. There is actually a debate on that medial temporal lobe epilepsy with hippocampal sclerosis is an epileptic syndrome. To address this issue, we searched for discriminative semiological features...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-017-8441-z

    authors: No YJ,Zavanone C,Bielle F,Nguyen-Michel VH,Samson Y,Adam C,Navarro V,Dupont S

    更新日期:2017-05-01 00:00:00

  • Dementia and assisted suicide and euthanasia.

    abstract::The number of dementia patients requesting euthanasia in the Netherlands has increased over the past five years. The issue is highly controversial. In this contribution we discuss some of the main arguments: the nature of suffering, the voluntariness of the request and the role of the physician. We argue that society ...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-016-8095-2

    authors: de Beaufort ID,van de Vathorst S

    更新日期:2016-07-01 00:00:00

  • Carotid endarterectomy in patients with recurrent symptoms associated with an ipsilateral carotid artery near occlusion with full collapse.

    abstract:OBJECTIVE:Near occlusion (NO) of the internal carotid artery (ICA) with full collapse (NOFC) is a rare condition, with a prevalence of around 1%. Guidelines on carotid stenosis recommend a conservative treatment in patients with a single-event ipsilateral to a NOFC, but the optimal treatment for patients with recurrent...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-018-8939-z

    authors: Meershoek AJA,Vonken EPA,Nederkoorn PJ,Kappelle LJ,de Borst GJ

    更新日期:2018-08-01 00:00:00

  • Copy number variations are a rare cause of non-CMT1A Charcot-Marie-Tooth disease.

    abstract::Hereditary peripheral neuropathies present a group of clinically and genetically heterogeneous entities. All known forms, including the various forms of Charcot-Marie-Tooth disease (CMT) are characterized as Mendelian traits and over 35 genes have been identified thus far. The mutational mechanism of the most common C...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-009-5401-2

    authors: Huang J,Wu X,Montenegro G,Price J,Wang G,Vance JM,Shy ME,Züchner S

    更新日期:2010-05-01 00:00:00

  • Characteristics associated with quality of life among people with drug-resistant epilepsy.

    abstract::Quality of Life (QoL) is the preferred outcome in non-pharmacological trials, but there is little UK population evidence of QoL in epilepsy. In advance of evaluating an epilepsy self-management course we aimed to describe, among UK participants, what clinical and psycho-social characteristics are associated with QoL. ...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-017-8512-1

    authors: Ridsdale L,Wojewodka G,Robinson E,Landau S,Noble A,Taylor S,Richardson M,Baker G,Goldstein LH,SMILE Team.

    更新日期:2017-06-01 00:00:00

  • Natural history of most common spinocerebellar ataxia: a systematic review and meta-analysis.

    abstract:BACKGROUND:Spinocerebellar ataxias (SCAs) are rare dominantly inherited neurodegenerative disorders that lead to severe disability and premature death. OBJECTIVE:To better characterize the natural history of the most common SCAs, SCA1, SCA2, SCA3 and SCA6, we performed a meta-analysis of literature to determine diseas...

    journal_title:Journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s00415-020-09815-2

    authors: Diallo A,Jacobi H,Tezenas du Montcel S,Klockgether T

    更新日期:2020-04-07 00:00:00

  • The metabolic and endocrine characteristics in spinal and bulbar muscular atrophy.

    abstract:OBJECTIVE:Spinal and bulbar muscular atrophy (SBMA) is caused by an abnormal expansion of the CAG repeat in the androgen receptor gene. This study aimed to systematically phenotype a German SBMA cohort (n = 80) based on laboratory markers for neuromuscular, metabolic, and endocrine status, and thus provide a basis for ...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-018-8790-2

    authors: Rosenbohm A,Hirsch S,Volk AE,Grehl T,Grosskreutz J,Hanisch F,Herrmann A,Kollewe K,Kress W,Meyer T,Petri S,Prudlo J,Wessig C,Müller HP,Dreyhaupt J,Weishaupt J,Kubisch C,Kassubek J,Weydt P,Ludolph AC

    更新日期:2018-05-01 00:00:00

  • Lipoic (thioctic) acid increases brain energy availability and skeletal muscle performance as shown by in vivo 31P-MRS in a patient with mitochondrial cytopathy.

    abstract::A woman affected by chronic progressive external ophthalmoplegia and muscle mitochondrial DNA deletion was studied by phosphorus magnetic resonance spectroscopy (31P-MRS) prior to and after 1 and 7 months of treatment with oral lipoic acid. Before treatment a decreased phosphocreatine (PCr) content was found in the oc...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00873552

    authors: Barbiroli B,Medori R,Tritschler HJ,Klopstock T,Seibel P,Reichmann H,Iotti S,Lodi R,Zaniol P

    更新日期:1995-07-01 00:00:00

  • Low prevalence of ataxic polyneuropathy in a community with high exposure to cyanide from cassava foods.

    abstract:INTRODUCTION:Ataxic polyneuropathy, which occurs in endemic form in an area in southwest Nigeria, is attributed to exposure to cyanide from cassava foods. Exposure to cyanide from cassava is, however, not exclusive to this endemic area. In this study, the occurrence of ataxic polyneuropathy was compared in two communit...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-002-0779-0

    authors: Oluwole OS,Onabolu AO,Cotgreave IA,Rosling H,Persson A,Link H

    更新日期:2002-08-01 00:00:00

  • Two cases of cerebral toxoplasmosis in AIDS patients mimicking HIV-related dementia.

    abstract::Two unusual cases of cerebral toxoplasmosis in AIDS patients are presented. Two homosexual males aged 33 and 52 years in CDC stage IV C1 complained of memory loss during the past 6 months, as well as weight loss and mild fever. They showed severe intellectual deterioration and discrete basal ganglia dysfunction. Motor...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00314650

    authors: Arendt G,Hefter H,Figge C,Neuen-Jakob E,Nelles HW,Elsing C,Freund HJ

    更新日期:1991-12-01 00:00:00

  • Euro-Esli: a European audit of real-world use of eslicarbazepine acetate as a treatment for partial-onset seizures.

    abstract::The Euro-Esli study was an exploratory pooled analysis of data from 14 European clinical practice studies, which was conducted to audit the real-world effectiveness, safety, and tolerability of eslicarbazepine acetate (ESL) as an adjunctive treatment for partial-onset seizures. Retention and effectiveness were assesse...

    journal_title:Journal of neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00415-017-8618-5

    authors: Villanueva V,Holtkamp M,Delanty N,Rodriguez-Uranga J,McMurray R,Santagueda P

    更新日期:2017-11-01 00:00:00

  • Disease management: the example of amyotrophic lateral sclerosis.

    abstract::Disease management is defined as any medical or pharmaceutical intervention designed to improve both outcomes for the patient and overall cost-effectiveness of the health plan. Disease management focuses on the patient throughout the entire course of the disease, involving both health providers and third-party payers....

    journal_title:Journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1007/pl00014806

    authors: Matheron L,Barrau K,Blin O

    更新日期:1998-08-01 00:00:00

  • Identification of the spinocerebellar ataxia type 7 mutation in Taiwan: application of PCR-based Southern blot.

    abstract::Spinocerebellar ataxia (SCA) type 7 is an autosomal dominant disorder characterized by neural loss, mainly in the cerebellum and regions of the brainstem and particularly the inferior olivary complex. This neurodegeneration disease is associated with expansion of unstable CAG repeats within the 5'-translated region of...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s004150070131

    authors: Hsieh M,Lin SJ,Chen JF,Lin HM,Hsiao KM,Li SY,Li C,Tsai CJ

    更新日期:2000-08-01 00:00:00

  • Step length predicts executive dysfunction in Parkinson's disease: a 3-year prospective study.

    abstract::Cognition and gait appear to be closely related. The chronological interplay between cognitive decline and gait dysfunction is not fully understood. The aim of the present prospective study is investigating whether the dysfunction of specific gait parameters, during specific task and medication conditions, may predict...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-018-8973-x

    authors: Amboni M,Iuppariello L,Iavarone A,Fasano A,Palladino R,Rucco R,Picillo M,Lista I,Varriale P,Vitale C,Cesarelli M,Sorrentino G,Barone P

    更新日期:2018-10-01 00:00:00

  • Dissecting aneurysm of intracranial vertebral artery: case report and review of literature.

    abstract::A spontaneous dissecting aneurysm of the intracranial portion of the dominant right vertebral artery presented as massive subarachnoid hemorrhage, excruciating headache, and respiratory arrest in a 57-year-old white man with a history of systemic hypertension. He died on the 3rd day. Postmortem examination revealed a ...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/BF00313594

    authors: Manz HJ,Luessenhop AJ

    更新日期:1983-01-01 00:00:00

  • A short scale for evaluation of neuropsychiatric disorders in Parkinson's disease: first psychometric approach.

    abstract::The neuropsychiatric symptoms and behavioral disorders affecting Parkinson's disease (PD) patients are common and disabling. A PD-specific interview-based 12-item scale, the Scale for Evaluation of Neuropsychiatric Disorders in Parkinson's Disease (SEND-PD), has been developed to assess the severity of neuropsychiatri...

    journal_title:Journal of neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00415-012-6490-x

    authors: Martinez-Martin P,Frades-Payo B,Agüera-Ortiz L,Ayuga-Martinez A

    更新日期:2012-11-01 00:00:00

  • Lumbar spinal stenosis: assessment of cauda equina involvement by electrophysiological recordings.

    abstract:UNLABELLED:The objective of this study was to investigate the relationship between electrophysiological recordings and clinical as well as radiological findings in patients suggestive to suffer from a lumbar spinal stenosis (LSS). We hypothesise that the electrophysiological recordings, especially SSEP, indicate a lumb...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-006-0427-1

    authors: Egli D,Hausmann O,Schmid M,Boos N,Dietz V,Curt A

    更新日期:2007-06-01 00:00:00

  • Female carriers of X-chromosomal adrenoleukodystrophy: a major differential diagnosis in progressive myelopathy.

    abstract::Adrenoleukodystrophy (ALD) and adrenomyeloneuropathy (AMN) are allelic X-chromosomal disorders of peroxisomal lipid metabolism due to mutations of the ABCD1-gene, leading, respectively, to leukoencephalopathy or myeloneuropathy in male patients. We report a family with two symptomatic carriers in subsequent generation...

    journal_title:Journal of neurology

    pub_type: 信件

    doi:10.1007/s00415-010-5505-8

    authors: Guettsches AK,Kuechler A,Gal A,Schmitz W,Tegenthoff M,Vorgerd M

    更新日期:2010-08-01 00:00:00

  • Gait analysis of sporadic and hereditary spastic paraplegia.

    abstract:OBJECTIVES:Sporadic (SSP) and hereditary spastic paraplegias (HSP) are clinically and genetically heterogeneous disorders, which are characterised by a slowly progressive spastic paraparesis. Initial symptoms and the rate of progression are variable even among members of the same family. Spastic paraparesis is the majo...

    journal_title:Journal of neurology

    pub_type: 杂志文章

    doi:10.1007/s00415-004-0366-7

    authors: Klebe S,Stolze H,Kopper F,Lorenz D,Wenzelburger R,Volkmann J,Porschke H,Deuschl G

    更新日期:2004-05-01 00:00:00

  • The genetics of ataxia: through the labyrinth of the Minotaur, looking for Ariadne's thread.

    abstract::Among the hereditary cerebellar ataxias (CAs), there are at least 36 different forms of autosomal dominant cerebellar ataxia (ADCAs), 20 autosomal recessive cerebellar ataxias (ARCAs), two X-linked ataxias, and several forms of ataxia associated with mitochondrial defects. Despite the steady increase in the number of ...

    journal_title:Journal of neurology

    pub_type: 杂志文章,评审

    doi:10.1007/s00415-014-7387-7

    authors: Mancuso M,Orsucci D,Siciliano G,Bonuccelli U

    更新日期:2014-09-01 00:00:00