Antibacterial activity of dentine primer containing MDPB after curing.

Abstract:

OBJECTIVES:A monomer methacryloyloxydodecylpyridinium bromide (MDPB) has antibacterial activity before polymerization. Furthermore, the antibacterial agent is immobilized by the polymerization of MDPB and the resin-based material incorporating MDPB is able to show an antibacterial effect even after being cured. The purpose of this study was to investigate the antibacterial effect of a dentine primer containing MDPB after curing. METHODS:The inhibitory effect of a cured MDPB-containing primer on the growth of Streptococcus mutans, Actinomyces viscosus and Lactobacillus casei was determined by the agar-disc method. The bactericidal activity of cured primer during a 1-h contact period was assessed using S. mutans, and the elution of unpolymerized MDPB was measured with high performance liquid chromatography. RESULTS:Cured MDPB-containing primer showed an inhibitory effect on the growth of all species which were in contact with the specimen surface, and displayed a little bactericidal effect on S. mutans without releasing any unpolymerized antibacterial components. CONCLUSION:Incorporation of antibacterial monomer MDPB into dentine primer is beneficial for providing antibacterial activity after curing.

journal_name

J Dent

journal_title

Journal of dentistry

authors

Imazato S,Ehara A,Torii M,Ebisu S

doi

10.1016/s0300-5712(97)00013-4

subject

Has Abstract

pub_date

1998-03-01 00:00:00

pages

267-71

issue

3

eissn

0300-5712

issn

1879-176X

pii

S0300571297000134

journal_volume

26

pub_type

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