Propofol-based versus fentanyl-isoflurane-based anesthesia for cardiac surgery.

Abstract:

OBJECTIVE:To evaluate drug costs, time of mechanical ventilation, complications, and hospital length of stay comparing propofol-based with fentanyl-isoflurane-based anesthesia. DESIGN:A prospective, randomized study. SETTING:A university-affiliated, tertiary care community hospital. PARTICIPANTS:Seventy patients undergoing primary coronary artery bypass surgery. INTERVENTIONS:Patients were randomized to either a low-dose fentanyl-isoflurane or a lower-dose fentanyl-isoflurane anesthetic supplemented with a continuous infusion of propofol. MEASUREMENTS AND MAIN RESULTS:Fentanyl-isoflurane anesthesia was significantly less expensive ($50.03+/-$27.26 v $121.69+/-$31.40) for anesthesia drugs and ($58.08+/-$27.39 v $129.91+/-$31.52) for total drug costs. There was also a trend for patients in the fentanyl-isoflurane group to be extubated slightly sooner (388+/-202 v 449+/-252 min) and go home sooner (5.1+/-1.8 v 6.0+/-3.0 days). CONCLUSION:Fentanyl-isoflurane provides an inexpensive anesthetic that permits as prompt an extubation as propofol, thus conserving resources for other patients.

authors

Engoren MC,Kraras C,Garzia F

doi

10.1016/s1053-0770(98)90328-7

subject

Has Abstract

pub_date

1998-04-01 00:00:00

pages

177-81

issue

2

eissn

1053-0770

issn

1532-8422

pii

S1053-0770(98)90328-7

journal_volume

12

pub_type

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