Early specification of striatal projection neurons and interneuronal subtypes in the lateral and medial ganglionic eminence.

abstract：:Persistence of horizontal cell (HC) light responses in extracellular solutions containing low Ca2+ plus divalent cations to block Ca2+ currents (ICa) has been attributed to Ca2+-independent neurotransmission. Using a retinal slice preparation to record both ICa and light responses, we demonstrate that persistence of H...

journal_title：Neuroscience

authors： Cadetti L,Thoreson WB,Piccolino M

更新日期：2004-01-01 00:00:00

abstract：:Puberty is a critical period of development during which the reemergence of gonadotropin-releasing hormone secretion from the hypothalamus triggers a cascade of hormone-dependent processes. Maturation of specific brain regions including the prefrontal cortex occurs during this window, but the complex mechanisms underl...

journal_title：Neuroscience

authors： Morrison KE,Rodgers AB,Morgan CP,Bale TL

更新日期：2014-04-04 00:00:00

abstract：:In a complex linguistic environment, while speech sounds can greatly vary, some shared features are often invariant. These invariant features constitute so-called abstract auditory rules. Our previous study has shown that with auditory sensory intelligence, the human brain can automatically extract the abstract audito...

journal_title：Neuroscience

authors： Guo XT,Wang XD,Liang XY,Wang M,Chen L

更新日期：2018-02-21 00:00:00

abstract：:Astrocytes have been generally believed to perform mainly homeostatic and supportive functions for neurons in the central nervous system. Recently, a growing body of evidence suggests previously unrecognized and surprising functions for astrocytes, including regulation of synaptic formation, transmission and plasticit...

journal_title：Neuroscience

authors： Adamsky A,Goshen I

更新日期：2018-02-01 00:00:00

abstract：:The present study was undertaken to investigate the possible effects of Spantide [D-Arg1, D-Trp7,9 Leu11]-substance P, a substance P antagonist, and of somatostatin on spinal cord blood flow. The experiments were performed with the laser-doppler technique on the L1 spinal cord segment exposed by laminectomy. The effec...

journal_title：Neuroscience

authors： Freedman J,Post C,Kåhrström J,Ohlen A,Mollenholt P,Owman C,Alari L,Hökfelt T

更新日期：1988-10-01 00:00:00

abstract：:Most functional imaging studies of memory retrieval investigate memory for standardized laboratory stimuli. However, naturally acquired autobiographical memories differ from memories of standardized stimuli in important ways. Neuroimaging studies of natural memories may reveal distinctive patterns of brain activation ...

journal_title：Neuroscience

authors： Maddock RJ,Garrett AS,Buonocore MH

更新日期：2001-01-01 00:00:00

abstract：:We investigated functional organization of the vagus nerve (N. X)- and glossopharyngeal nerve (N. IX)-related nuclei in the embryonic rat brainstem and compared their development and spatial distribution patterns, using multiple-site optical recording with a fast voltage-sensitive dye, NK2761. Intact brainstem prepara...

journal_title：Neuroscience

authors： Momose-Sato Y,Nakamori T,Sato K

更新日期：2011-09-29 00:00:00

abstract：:It is well established that women experience major depression at roughly twice the rate of men. Interestingly, accumulating clinical and experimental evidence shows that the responsiveness of males and females to antidepressant pharmacotherapy, and particularly to tricyclic antidepressants (TCAs), is sex-differentiate...

journal_title：Neuroscience

authors： Pitychoutis PM,Dalla C,Sideris AC,Tsonis PA,Papadopoulou-Daifoti Z

更新日期：2012-05-17 00:00:00

abstract：:Studies in experimental animals have revealed important roles of neuroactive steroids in the control of central nervous system functions during physiological and pathological conditions, suggesting that they may represent good candidates for the development of neuroprotective strategies for neurodegenerative and psych...

journal_title：Neuroscience

authors： Melcangi RC,Panzica G,Garcia-Segura LM

更新日期：2011-09-15 00:00:00

abstract：:In genetically-modified Lmx1b(f/f/p) mice, selective deletion of LMX1B in Pet-1 expressing cells leads to failure of embryonic development of serotonin (5-HT) neurons. As adults, these mice have a decreased hypercapnic ventilatory response and abnormal thermoregulation. This mouse model has been valuable in defining t...

journal_title：Neuroscience

authors： Cerpa V,Gonzalez A,Richerson GB

更新日期：2014-10-24 00:00:00

abstract：:The possible roles of G-protein coupled metabotropic glutamate receptors in central nervous function are currently the focus of intensive investigation. The complexity of effects produced by agonists at these receptors probably reflects the activity of a range of sub-types. The metabotropic glutamate receptors first d...

journal_title：Neuroscience

authors： Birse EF,Eaton SA,Jane DE,Jones PL,Porter RH,Pook PC,Sunter DC,Udvarhelyi PM,Wharton B,Roberts PJ

更新日期：1993-02-01 00:00:00

abstract：:Agrin, a synaptic basal lamina protein, is essential for the formation of the vertebrate neuromuscular junction. Agrin's role in synaptogenesis in the central nervous system has, however, not been elucidated. Therefore, we performed immunohistochemical analysis of agrin localization in adult rat brain using agrin-spec...

journal_title：Neuroscience

authors： Cohen NA,Kaufmann WE,Worley PF,Rupp F

更新日期：1997-01-01 00:00:00

abstract：:Glial cell line-derived neurotrophic factor (GDNF) is a potent factor for the ventral mesencephalic dopamine neurons. However, studies on the Gdnf gene deleted (Gdnf(-/-)) mouse have been limited to fetal tissue since these mice die prematurely. To evaluate long-term effects of Gdnf gene deletion, this study involves ...

journal_title：Neuroscience

authors： Nevalainen N,Chermenina M,Rehnmark A,Berglöf E,Marschinke F,Strömberg I

更新日期：2010-12-29 00:00:00

abstract：:The incidence of asthma is more common in boys than in girls during the childhood, and more common in premenopausal female than age-matched males. Our previous study demonstrated a gender difference in histamine-mediated neuroexcitability in nodose ganglia neurons (NGNs), highlighting a possibility of histamine-mediat...

journal_title：Neuroscience

authors： Li JN,Li XL,He J,Wang JX,Zhao M,Liang XB,Zhao SY,Ma MN,Liu Y,Wang YB,Chen H,Qiao GF,Li BY

更新日期：2015-09-10 00:00:00

abstract：:Activation of muscarinic receptors leads to proliferation of astroglial cells and this effect is inhibited by ethanol. Among the intracellular pathways involved in the mitogenic action of muscarinic agonists, activation of the atypical protein kinase C zeta (PKC zeta) appears to be of most importance, and is also affe...

journal_title：Neuroscience

authors： Guizzetti M,Bordi F,Dieguez-Acuña FJ,Vitalone A,Madia F,Woods JS,Costa LG

更新日期：2003-01-01 00:00:00

abstract：:The mirror neuron system (MNS) is currently one of the most prominent areas of research in neuroscience. Some of the work has focused on the identification of factors that modulate its activity, but until now, no one has tried to identify the effect of motor ability on the MNS regions. The aim of the present work is t...

journal_title：Neuroscience

authors： Plata Bello J,Modroño C,Marcano F,González-Mora JL

更新日期：2014-09-05 00:00:00

abstract：:Despite extensive investigations into the mechanisms of aerobic respiration in mitochondria, the spontaneous metabolic activity of individual cells within a whole animal has not been observed in real time. Consequently, little is known about whether and how the level of mitochondrial energy metabolism is regulated in ...

journal_title：Neuroscience

authors： Kazama H,Ichikawa A,Kohsaka H,Morimoto-Tanifuji T,Nose A

更新日期：2008-03-03 00:00:00

abstract：:The aim of this study was to test a possible role of A5 neurons in the expression of the pressor and tachycardic responses to conditioned fear and restraint, two forms of psychological stress. Previous Fos studies have shown that the C1 adrenergic neurons and spinally projecting neurons in the vasopressor region of th...

journal_title：Neuroscience

authors： Vianna DM,Carrive P

更新日期：2010-04-14 00:00:00

abstract：:The cortical representation of the body surface is not fixed, but rather, is continuously modified by ongoing changes in sensory experience. Although the cellular and molecular mechanisms that subserve these changes are uncertain, increasing evidence suggests that synaptically-released zinc may play a role. Zinc is re...

journal_title：Neuroscience

authors： Brown CE,Dyck RH

更新日期：2005-01-01 00:00:00

abstract：:The present studies aimed to determine whether estradiol (E(2)) modulates the stimulation of cocaine- and amphetamine-regulated transcript (CART) peptide in the mesolimbic and nigrostriatal dopaminergic systems. I.c.v. administration of the CART peptide (55-102, 1 microg/3 microl) increased dopamine turnover (3,4-dihy...

journal_title：Neuroscience

authors： Shieh KR,Yang SC

更新日期：2008-07-17 00:00:00

abstract：:Retinal ganglion cell axons of the DBA/2J mouse model of glaucoma, a model characterized by extensive neuroinflammation, preserve synaptic contacts with their subcortical targets for a time after onset of anterograde axonal transport deficits, axon terminal hypertrophy, and cytoskeletal alterations. Though retrograde ...

journal_title：Neuroscience

authors： Smith MA,Plyler ES,Dengler-Crish CM,Meier J,Crish SD

更新日期：2018-10-15 00:00:00

abstract：:The study explored unintentional force changes elicited by removing visual feedback during cyclical, two-finger isometric force production tasks. Subjects performed two types of tasks at 1Hz, paced by an auditory metronome. One - Force task - required cyclical changes in total force while maintaining the sharing, defi...

journal_title：Neuroscience

authors： Reschechtko S,Hasanbarani F,Akulin VM,Latash ML

更新日期：2017-05-14 00:00:00

abstract：:The purpose of this study was to experimentally investigate the applicability of the equilibrium-point hypothesis to the dynamics of single-joint movements. Subjects were trained to perform relatively slow (movement time 600-1000 ms) or fast (movement time 200-300 ms) single-joint elbow flexion movements against a con...

journal_title：Neuroscience

authors： Latash ML,Gottlieb GL

更新日期：1991-01-01 00:00:00

abstract：:Inside-out patch recordings from rat acutely dissociated cerebral cortical neurons revealed time and voltage-dependent activity of a large-conductance calcium-activated potassium channel. Channel activity inactivated within minutes following a depolarizing voltage step, and was recovered from inactivation by membrane ...

journal_title：Neuroscience

authors： Smith MA,Ashford ML

更新日期：2000-01-01 00:00:00

abstract：:Training of a musical skill is known to produce a distributed neural representation of the ability to perceive music and perform musical tasks. In the present study we tested the hypothesis that the audiovisual perception of music involves a wider activation of multimodal sensory and sensorimotor structures in the bra...

journal_title：Neuroscience

authors： Srinivasan N,Bishop J,Yekovich R,Rosenfield DB,Helekar SA

更新日期：2020-10-15 00:00:00

abstract：:Stimulation of cervical vagal afferents inhibits central sympathetic outflows in part by inhibiting the ongoing activity of putative baroreceptive neurons in the rostral ventrolateral medulla oblongata. The aim of the present study was to examine the electrophysiological characteristics of vagal responses and their in...

journal_title：Neuroscience

authors： Zagon A,Rocha I,Ishizuka K,Spyer KM

更新日期：1999-01-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder for which there is currently no effective treatment. Studies indicate that enhancing autophagy in mouse models of neurodegenerative disease can ameliorate the behavioral symptoms and pathological damage associated with the accumulation of pathol...

journal_title：Neuroscience

authors： Li Y,Guo Y,Wang X,Yu X,Duan W,Hong K,Wang J,Han H,Li C

更新日期：2015-07-09 00:00:00

abstract：:The cellular mechanisms underlying the genesis of thalamic ponto-geniculo-occipital waves were studied in reserpinized cats under urethane anaesthesia. Simultaneous field potential and intracellular recordings were performed in the lateral geniculate nucleus after acute lesions of retinal and visual cortical inputs. I...

journal_title：Neuroscience

authors： Hu B,Steriade M,Deschênes M

更新日期：1989-01-01 00:00:00

abstract：:Synucleinopathies including Parkinson's disease (PD) are characterized by the accumulation of alpha-synuclein (α-syn) within neural cell bodies and their processes. Transgenic mice overexpressing human wild-type or mutant forms of α-syn under the control of different promoters were developed to analyse the underlying ...

journal_title：Neuroscience

authors： May VE,Nuber S,Marxreiter F,Riess O,Winner B,Winkler J

更新日期：2012-10-11 00:00:00

abstract：:In the present study the effect of cocaine on thymidine, uridine and leucine incorporation was assessed in primary cortical glial and C6 glioma cells. Cocaine exposure for 24 h inhibited thymidine and uridine incorporation in cortical glial and C6 glioma cells. However, the effect of cocaine on uridine incorporation w...

journal_title：Neuroscience

authors： Garg UC,Turndorf H,Bansinath M

更新日期：1993-11-01 00:00:00