Abstract:
:This article describes the results of studies conducted to determine the usefulness of reflex changes as markers of disease severity in Alzheimer's disease (AD). Standardized and quantified muscle stretch reflexes, cutaneous reflexes, and developmental (primitive) reflexes were studied in normal older adults, in individuals with mild memory impairment, and in patients with AD, in all clinical severity stages as assessed with the Global Deterioration Scale (GDS), the Mini-Mental State Examination (MMSE), and the Functional Assessment Staging (FAST) procedure. Changes in frequency and intensity of these individual reflex variables, as well as of variables consisting of combinations of these individual reflexes, appeared to be sensitive indicators of the progression of AD. These neurological reflex variables showed high Pearson correlations with the GDS (.72), the MMSE (.74), and the FAST (.80). Standardized quantified neurological reflex measures are useful as noncognitive, education-independent, and culture-independent markers of the course of AD.
journal_name
Int Psychogeriatrjournal_title
International psychogeriatricsauthors
Franssen EH,Reisberg Bdoi
10.1017/s1041610297005036subject
Has Abstractpub_date
1997-01-01 00:00:00pages
297-306; discussion 317-21eissn
1041-6102issn
1741-203Xjournal_volume
9 Suppl 1pub_type
杂志文章abstract:BACKGROUND:Verbal fluency (VF) tasks are simple and efficient clinical tools to detect executive dysfunction and lexico-semantic impairment. VF tasks are widely used in patients with suspected dementia, but their accuracy for detection of mild cognitive impairment (MCI) is still under investigation. Schooling in partic...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610209990639
更新日期:2009-12-01 00:00:00
abstract::Cross-sectional data from Phase 1 of the Canadian Study of Health and Aging was used to examine the relationship between two self-report health measures: "How would you say your health is these days?"(HEALTH) and "How much do your health troubles stand in the way of your doing the things you want to do?"(TROUBLE). The...
journal_title:International psychogeriatrics
pub_type: 杂志文章,多中心研究
doi:10.1017/s1041610202008165
更新日期:2001-01-01 00:00:00
abstract::ABSTRACTBackground and Purpose:The impact of dementia-related stressors and strains have been examined for their potential to threaten the well-being of either the person with dementia or the family care partner, but rarely have studies considered the dyadic nature of well-being in dementia. The purpose of this study ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161021800203X
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:The Family Group Conference (FGC) is an approach to partnership working which brings together service users, their support network and care professionals in a family-led decision making forum. Evidence, though limited, indicates that that FGC can enhance outcomes for service providers and their users. This s...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610215001507
更新日期:2016-02-01 00:00:00
abstract::Current approaches to the diagnosis of delirium are based upon the recognition of symptoms that emerge in the pathological state. As an alternative, we propose an approach to case identification for research purposes based on the recognition of significant changes in the cognitive or cerebral state of the individual p...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s104161029100073x
更新日期:1991-01-01 00:00:00
abstract::ABSTRACTBackground:Delirium is a complex clinical syndrome characterized by disturbed consciousness, cognitive function, or perception and associated with serious adverse outcomes such as death, dementia, and the need for long-term care. However, recognition and management of delirium is poorly prioritized even though...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218001369
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:The aim of this study was to investigate the clustering of symptoms on the Neuropsychiatric Inventory (NPI) and the relative prevalence of symptom clusters in mild and moderate Alzheimer's disease (AD). METHODS:Confirmatory factor analysis (CFA) was performed on the polychoric correlation matrix of 12 NPI i...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212000609
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Behavioral and psychological symptoms of dementia (BPSD) cause caregiver distress and earlier institutionalization. We compared the prevalence and characteristics of BPSD between institution residents and memory clinic outpatients with Alzheimer's disease (AD) to test the hypothesis that there is more BPSD a...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610209990767
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:Mental capacity has been little studied among older general hospital inpatients. METHODS:A retrospective analysis was undertaken of routinely collected data (age, gender, ethnicity, admission diagnosis, psychiatric diagnosis, Mini-mental State Examination score, whether capacity was assessed, the outcome of...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161020900917X
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Concerns about suicide risk in people with dementia have been increasing in recent years along with a discourse about rational suicide and assisted suicide. METHODS:A systematic narrative literature review of suicidal behavior and assisted suicide in persons with dementia. RESULTS:Most studies that have ex...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/S1041610215000629
更新日期:2015-10-01 00:00:00
abstract::Although individuals aged 65 and over accounted for 12% of the total population of Japan in 1990, suicides in this age group consisted of 29% of all suicides. The elderly population of Japan is expected to grow rapidly to 24% of the total population by the year 2020, and suicide prevention for the elderly is an urgent...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610295002006
更新日期:1995-07-01 00:00:00
abstract:BACKGROUND:Whilst previous surveys of mental health literacy of general practitioners (GPs) have shown high rates of recognition of common mental disorders, few studies have been carried out into GPs' understanding of presentations in late life. This study aims to determine GPs' recognition of mental disorders in older...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610208008235
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Eating disorders in the elderly are often overlooked. When they occur, significant morbidity and mortality result. In this study we review all existing literature on eating disorders in the elderly and provide practical guidelines for clinicians in recognizing and managing eating disorders in the elderly. M...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610210000104
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Most studies examining psychotropic medication use on cognition in older persons with dementia include measures of global cognitive function. The present study examined the relationship between different types of psychotropic medication and specific cognitive functions in older people with dementia. METHODS...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610209008552
更新日期:2009-04-01 00:00:00
abstract::The dynamic processes and the way they interact in shaping a care system for demented patients are analyzed and discussed. The development of disability/dependency, interpreted in a simulation model based on Katz's index of ADL and Berger's scale "Rating the severity of senility," gave insight into the interplay of fo...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610296002888
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate survival time and life-expectancy in people with young-onset dementia (YOD) and to examine the relationship with age, sex, dementia subtype and comorbidity. DESIGN, SETTING AND PARTICIPANTS:Survival was examined in 198 participants in the Needs in Young-onset Dementi...
journal_title:International psychogeriatrics
pub_type: 杂志文章,多中心研究
doi:10.1017/S1041610219000152
更新日期:2019-12-01 00:00:00
abstract::Few instruments are available with which to measure behavioral and psychological signs and symptoms in Hispanic patients with dementia. Therefore, the aim of the current study was to develop and evaluate a 17-item scale adapted from the Revised Memory and Behavior Problems Checklist. This measure, the Behavior Problem...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610201007438
更新日期:2001-03-01 00:00:00
abstract:BACKGROUND:The economic cost of dementia is high and can be predicted by cognitive and neuropsychiatric profiles. The differential costs of the various subtypes of dementia are unknown in Argentina, and this study therefore aimed to compare these costs. METHODS:Patients with a diagnosis of dementia of Alzheimer-type (...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610210002012
更新日期:2011-05-01 00:00:00
abstract:UNLABELLED:The aim of the current study was to test the properties of a scale especially developed for use in epidemiological surveys in low sociocultural populations, and to determine whether this scale can be used in a clinical population. MATERIAL AND METHODS:Two hundred fifty subjects took part; 150 were controls ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610200006323
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:Preliminary evidence indicates that the quality of the carer-care recipient relationship predicts those carers most at risk from anxiety. Attachment style is related to higher carer burden, psychological morbidity and increased care recipient institutionalization. We tested, for the first time, the hypothesi...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161020700645X
更新日期:2008-06-01 00:00:00
abstract::ABSTRACTBackground:Walking ability recently emerged as a sub-clinical marker of cognitive decline. Hence, the relationship between baseline gait and future cognitive decline was examined in geriatric patients. Because a "loss of complexity" (LOC) is a key phenomenon of the aging process that exhibits in multiple syste...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217002770
更新日期:2018-09-01 00:00:00
abstract::This case describes the differential diagnosis and treatment of a 70-year-old man with an avoidant personality disorder. It illustrates that diagnostic assessment and treatment of personality problems in the elderly are possible in mental health care. It demonstrates that multiple stand-alone treatment modules can for...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610210001948
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVES:To explore the extent to which staff members in long-term care facilities (LTCF) have experienced situations of sexual harassment, how they commonly and ideally manage the situation, and how their work position influences their responses. DESIGN:Cross-sectional quantitative study, using the vignette techniq...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610219001431
更新日期:2020-03-01 00:00:00
abstract::I read with great interest the study of Petrazzuoli et al. (2017) on exploring dementia management attitudes in primary care. The authors made a laudable effort to evaluate this important issue, which certainly needs timely attention. The high response rate from 25 member countries of the European General Practice Res...
journal_title:International psychogeriatrics
pub_type: 评论,信件
doi:10.1017/S1041610217003003
更新日期:2018-09-01 00:00:00
abstract::Dementia can interfere with the maintenance of social interactions. The ability to participate in social interactions is one of the elements that enables good social health (Hubert et al., 2011), and having dementia does not automatically eliminates the person's opportunity to have good social health (Vernooij-Dassen ...
journal_title:International psychogeriatrics
pub_type: 信件
doi:10.1017/S1041610217002046
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Mild cognitive impairment (MCI) is proposed to describe the transitional stage between normal cognitive aging and dementia. It has had significant impact in the field of dementia research, but it remains controversial whether or not it should be used as a diagnostic category in clinical practice. METHODS:Se...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610208007126
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:Emotional distress associated with Parkinson's disease (PD) increases disease burden and decreases functioning. The literature supports the benefits of psychological interventions for amelioration of emotional distress in persons with PD. The objective of this study is to apply the Contextual Adult Lifespan ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610216000569
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Alterations in iron metabolism have been suggested as potential pathological markers in patients with manifest depression. No data on the association between iron and depression exist from population-based studies, in which milder forms of depressive symptoms are much more common. The aim of this study was t...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610205002759
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVES:To evaluate the impact of external memory devices on the efficacy of a package of internal mnemonic techniques. Participants wrote two types of lists during the study phase: (a) a list of study words and/or (b) a loci list. At recall, participants were not allowed to refer to either of the lists they had wri...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610203008755
更新日期:2003-03-01 00:00:00
abstract::The purpose of this study was to examine the relationship between age-associated changes in central serotonergic function and abnormalities associated with major depression. Under randomized double-blind conditions, prolactin and cortisol responses to the serotonin-releasing agent d,l-fenfluramine hydrochloride (60 mg...
journal_title:International psychogeriatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s1041610296002499
更新日期:1996-04-01 00:00:00