Epidemiology, prevention, and early detection of breast cancer.

abstract：:Over the past year, several research areas have been noteworthy. This article discusses decision making related to breast cancer treatment, the effects of treatment on measures of psychological distress, and studies related to quality-of-life among breast cancer patients. In addition, an area of continued interest inv...

journal_title：Current opinion in oncology

authors： Stefanek ME

更新日期：1993-11-01 00:00:00

abstract：:Thyroid cancers are still the most common endocrine cancers. They are dominated by well-differentiated carcinomas, including papillary carcinoma, follicular carcinoma, and medullary thyroid carcinoma. Diagnosis is based on fine-needle aspiration cytologic examination. Recently, reverse transcription polymerase chain r...

journal_title：Current opinion in oncology

authors： Bi J,Lu B

更新日期：2000-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize recent developments and controversies in the diagnosis and management of nonmuscle invasive bladder cancer (NMIBC). RECENT FINDINGS:The majority of incident bladder cancer diagnoses are noninvasive. The mainstay of diagnosis remains cystoscopy and transurethral resection, with enhanced o...

journal_title：Current opinion in oncology

authors： Bassett JC,Eifler JB,Resnick MJ,Clark PE

更新日期：2014-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The worldwide incidence of melanoma and nonmelanoma skin cancers is increasing alarmingly. The development of new techniques such as dermoscopy leads to a consequent progress in skin cancers screening. The purpose of this review is to highlight recent advances in dermoscopy, reviewing primary research...

journal_title：Current opinion in oncology

authors： Massone C,Di Stefani A,Soyer HP

更新日期：2005-03-01 00:00:00

abstract：PURPOSE OF REVIEW:In this review, we highlight key recent insights into hematopoiesis and hematological malignancies through the application of novel single-cell approaches. We particularly focus on biological insights made through the study of stem/progenitors cells in myeloid malignancy at single-cell resolution. RE...

journal_title：Current opinion in oncology

authors： Brierley CK,Mead AJ

更新日期：2020-03-01 00:00:00

abstract：:The incidence of lung cancer continues to rise. The need and demand for more effective treatment to improve survival and palliate symptoms increases at a great rate. The most recent evidence for the use of chemotherapy in the palliative setting is summarized in this review of the literature from the last few years. It...

journal_title：Current opinion in oncology

authors： Medley L,Cullen M

更新日期：2002-07-01 00:00:00

abstract：:The publication of the proceedings of Fourth Workshop on Carcinoma in situ was an impressive leap in our understanding of the interaction between prenatal and postpubertal factors in the development of germ cell cancer as well as increased insight into the molecular events that are involved in the development of these...

journal_title：Current opinion in oncology

authors： Oliver RT

更新日期：1999-05-01 00:00:00

abstract：:A review of the recent literature about liver cancers shows the increasing role of hepatitis C as a risk factor for the development of hepatocellular carcinoma. A new discussion has arisen with regard to the association between the use of oral contraceptives and hepatocellular carcinoma. Patients at risk for developin...

journal_title：Current opinion in oncology

authors： Weimann A,Oldhafer KJ,Pichlmayr R

更新日期：1995-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to highlight recent studies on mammalian sirtuins that coordinately regulate cellular metabolic homeostasis upon fasting and to summarize the beneficial effects of fasting on carcinogenesis and cancer therapy. RECENT FINDINGS:Recent studies have demonstrated that fasting...

journal_title：Current opinion in oncology

authors： Zhu Y,Yan Y,Gius DR,Vassilopoulos A

更新日期：2013-11-01 00:00:00

abstract：:The bcr-abl fusion protein is present in the vast majority of cases of chronic myelogenous leukemia, and the deregulated tyrosine kinase activity of this protein is essential for leukemic transformation. Thus, bcr-abl is an ideal target for pharmacologic inhibition. In preclinical studies, ST1571 (formerly CGP57148B),...

journal_title：Current opinion in oncology

authors： O'Dwyer ME,Druker BJ

更新日期：2000-11-01 00:00:00

abstract：:The prognosis of pediatric low-grade gliomas is relatively favorable, but residual or unresectable tumors remain a challenge. Conventional radiation therapy is effective but may be associated with unacceptable sequelae in young children. Chemotherapy can delay the need for radiation therapy in young children; however,...

journal_title：Current opinion in oncology

authors： Schmandt SM,Packer RJ

更新日期：2000-05-01 00:00:00

abstract：:Prophylactic platelet transfusion can prevent spontaneous hemorrhage in thrombocytopenic cancer patients undergoing intensive treatment, but it is limited by the development of platelet alloimmunization. Exclusive use of leukocyte-depleted blood products delays or prevents the development of platelet alloimmunization ...

journal_title：Current opinion in oncology

authors： Wallerstein R Jr,Deisseroth AB

更新日期：1991-08-01 00:00:00

abstract：:In testicular cancer epidemiology, the increasing recognition that germinal epithelial atrophy is the final common pathway in the development of this tumor has developed along with reports that elevated follicule-stimulating hormone levels at the time of diagnosis of first tumor correlate with risk of developing a sec...

journal_title：Current opinion in oncology

authors： Oliver RT

更新日期：1991-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Advances in the health system and medical sciences are continuously pushing the barrier of life-expectancy. As a consequence, humans are being increasingly afflicted by age-associated diseases, such as cancer. The challenge now lies in understanding the mechanisms underlying ageing in order to reduce ...

journal_title：Current opinion in oncology

authors： Pereira B,Ferreira MG

更新日期：2013-01-01 00:00:00

abstract：PURPOSE OF REVIEW:In the 1990s, cancer patients were described as poor candidates for ICU admission on the basis of high mortality rates and management costs. Over the last decade, however, advances in the management of malignancies and organ failures have led to substantial increases in survival. This review discusses...

journal_title：Current opinion in oncology

authors： Darmon M,Azoulay E

更新日期：2009-07-01 00:00:00

abstract：:Some of the most dramatic advances in the treatment of cancer have used the immune system in combination with conventional or transplantation chemotherapy. Adoptive immunotherapy has been used for relapses after allogeneic bone marrow transplantation, and it has been particularly effective for chronic myeloid leukemia...

journal_title：Current opinion in oncology

authors： Ballen K,Stewart FM

更新日期：1997-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Atypical lipomatous tumors/well-differentiated liposarcomas (ALT/WDLs) are one of the more frequent mesenchymal neoplasms and are characterized by specific chromosome aberrations: supernumerary chromosome or giant marker chromosome or both. Extra copies of known oncogenes such as MDM2, CDK4, SAS, HMGA...

journal_title：Current opinion in oncology

authors： Arrigoni G,Doglioni C

更新日期：2004-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The treatment of HIV infection has been transformed by the introduction of highly active antiretroviral therapy. For patients who respond and can tolerate lifelong therapy, HIV infection may become a chronic disease requiring long-term ambulatory care follow-up. The current management of antiretrovira...

journal_title：Current opinion in oncology

authors： Kalkut G

更新日期：2005-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Over the past 20 years, tremendous strides have been made to decrease treatment-related morbidity and mortality following allogeneic transplant, including management of acute and chronic lung injury. Within this context, three distinct entities are recognized, idiopathic pneumonia syndrome (IPS), bron...

journal_title：Current opinion in oncology

authors： Yanik G,Kitko C

更新日期：2013-03-01 00:00:00

abstract：:This review highlights recent advances in understanding the mode of action of retinoids at the level of molecular and cellular biology in relation to the new clinical results achieved with retinoids in various malignancies. All-trans-retinoic acid has been established in the clinic as a first-line differentiation ther...

journal_title：Current opinion in oncology

authors： Holdener EE,Bollag W

更新日期：1993-11-01 00:00:00

abstract：PURPOSE OF REVIEW:PremRNA alternative splicing is more a rule than an exception as it affects more than 90% of multiexons genes and plays a key role in proteome diversity. Here, we discuss some recent studies published in the extensively growing field linking RNA splicing and cancer. RECENT FINDINGS:These last years, ...

journal_title：Current opinion in oncology

authors： Abou Faycal C,Gazzeri S,Eymin B

更新日期：2016-01-01 00:00:00

abstract：PURPOSE OF REVIEW:More therapeutic options are needed for bone and soft tissue sarcomas, especially for patients with metastatic disease. Recent randomized clinical trials conducted in colon, breast and lung cancer have shown the anti-vascular endothelial growth factor agent, bevacizumab, alone or in combination with c...

journal_title：Current opinion in oncology

authors： Balasubramanian L,Evens AM

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This review focuses on the current concepts relating to the use of radiation therapy in the care of surgical patients with retroperitoneal sarcoma. Radiation therapy for retroperitoneal sarcoma patients is complex because it requires decisions on not only the timing of administration, but also the tec...

journal_title：Current opinion in oncology

authors： Pawlik TM,Ahuja N,Herman JM

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Myelodysplastic syndromes (MDSs) are rare disorders in children, showing peculiar clinical manifestations and biological features. This review will summarize biological, genetic and clinical features of childhood MDS and will provide an update of the algorithm of treatment of the different disease var...

journal_title：Current opinion in oncology

authors： Galaverna F,Ruggeri A,Locatelli F

更新日期：2018-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Myxoid/round cell liposarcoma (MRCL) represents about 10% of all soft-tissue sarcomas. Therapeutic options for this subgroup of tumours are limited, essentially doxorubicin-based regimens and trabectedin. Recently, the mammalian target of rapamycin (mTOR) pathway has been identified as a therapeutic t...

journal_title：Current opinion in oncology

authors： Sanfilippo R,Dei Tos AP,Casali PG

更新日期：2013-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The phosphoinositide 3-kinases are lipid kinases that are activated in response to external factors. They regulate a number of intracellular signaling pathways involved in cell motility, metabolism, survival, and growth. This review summarizes the current knowledge about specific contributions of Clas...

journal_title：Current opinion in oncology

authors： Wee S,Lengauer C,Wiederschain D

更新日期：2008-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The remarkable progress witnessed over the past few years in the diagnosis, prognosis, and therapy of chronic lymphocytic leukemia has profoundly changed the clinical approach to this disease. This review focuses on the most recent advances in the diagnostic and prognostic examination of patients with...

journal_title：Current opinion in oncology

authors： Gentile M,Mauro FR,Guarini A,Foà R

更新日期：2005-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to update knowledge on therapy-related myeloid neoplasms (t-MN), taking into account the new 2008 WHO classification, new genome-wide approaches for the definition of susceptibility towards t-MN and the introduction of new more aggressive treatments in cancer patients. R...

journal_title：Current opinion in oncology

authors： Leone G,Fianchi L,Voso MT

更新日期：2011-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe recent advances in the diagnosis and treatment of paraneoplastic neurological syndromes (PNS). RECENT FINDINGS:PNS are rare complications of cancer caused by an immune cross-reaction between antigens expressed by tumor cells and neurons. The target of the immune attack can be an intracell...

journal_title：Current opinion in oncology

authors： Berzero G,Psimaras D

更新日期：2018-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to describe the major steps leading to the immunosuppressive tumor microenvironment and to summarize some of the new immunotherapies that interfere with these mechanisms. RECENT FINDINGS:Immunotherapy has improved the outcome of relapsed/metastatic head and neck squamous cel...

journal_title：Current opinion in oncology

authors： Merlano MC,Denaro N,Garrone O

更新日期：2020-05-01 00:00:00