Technical foundations and pitfalls of clinical fMRI.

Abstract:

:Magnetic resonance imaging (MRI) has become an established and invaluable tool in the diagnosis of numerous diseases through its ability to show pathologic contrast in images of soft tissue. More recently, MRI has found application in the study of organ function, principally in the brain and heart. This article deals with MRI imaging of brain function and describes some of the techniques that allow physiological parameters such as cerebral blood volume, cerebral blood oxygenation, and cerebral perfusion to be determined. Additionally, some of the potentially confounding influences in these experiments are discussed.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Jezzard P,Song AW

doi

10.1006/nimg.1996.0056

subject

Has Abstract

pub_date

1996-12-01 00:00:00

pages

S63-75

issue

3 Pt 3

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(96)90056-7

journal_volume

4

pub_type

杂志文章,评审
  • In vivo assessment of human visual system connectivity with transcranial electrical stimulation during functional magnetic resonance imaging.

    abstract::Functional magnetic resonance imaging (fMRI) was used to investigate local and distant cerebral activation induced by transcranial electrical stimulation in order to noninvasively map functional connectivity in the human visual system. Stimulation with lateromedially directed currents and the anode 4.5 cm dorsally to ...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2001.0847

    authors: Brandt SA,Brocke J,Röricht S,Ploner CJ,Villringer A,Meyer BU

    更新日期:2001-08-01 00:00:00

  • Increased neural responses to unfairness in a loss context.

    abstract::Unfairness plays an important role in economic decision making. This fMRI study sought to investigate how the loss and the gain contexts could modulate behavioral and brain responses to unfairness by focusing on participants' rejection behaviors during an Ultimatum Game paradigm. Participants were scanned while they w...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2013.03.048

    authors: Guo X,Zheng L,Zhu L,Li J,Wang Q,Dienes Z,Yang Z

    更新日期:2013-08-15 00:00:00

  • The influence of the diffusion of responsibility effect on outcome evaluations: electrophysiological evidence from an ERP study.

    abstract::Previous studies have revealed that personal responsibility has an influence on outcome evaluation, although the way this influence works is still unclear. This study imitated the phenomenon of responsibility diffusion in a laboratory to examine the influence of the effect of responsibility diffusion on the processing...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2010.04.275

    authors: Li P,Jia S,Feng T,Liu Q,Suo T,Li H

    更新日期:2010-10-01 00:00:00

  • Integrating functional near-infrared spectroscopy in the characterization, assessment, and monitoring of cancer and treatment-related neurocognitive dysfunction.

    abstract::Cancer and cancer treatment-related neurocognitive dysfunction (CRND) (e.g., impairments in key cognitive domains of attention, memory, processing speed, and executive function), commonly referred to as "chemobrain" or "chemo-fog", can negatively impact patients' psychosocial functioning and quality of life. CRND is a...

    journal_title:NeuroImage

    pub_type: 杂志文章,评审

    doi:10.1016/j.neuroimage.2013.06.075

    authors: Jean-Pierre P

    更新日期:2014-01-15 00:00:00

  • A novel framework for segmentation of deep brain structures based on Markov dependence tree.

    abstract::The aim of this work is to develop a new framework for multi-object segmentation of deep brain structures (caudate nucleus, putamen and thalamus) in medical brain images. Deep brain segmentation is difficult and challenging because the structures of interest are of relatively small size and have significant shape vari...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2009.03.010

    authors: Wu J,Chung AC

    更新日期:2009-07-15 00:00:00

  • Precise Inference and Characterization of Structural Organization (PICASO) of tissue from molecular diffusion.

    abstract::Inferring the microstructure of complex media from the diffusive motion of molecules is a challenging problem in diffusion physics. In this paper, we introduce a novel representation of diffusion MRI (dMRI) signal from tissue with spatially-varying diffusivity using a diffusion disturbance function. This disturbance f...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2016.09.057

    authors: Ning L,Özarslan E,Westin CF,Rathi Y

    更新日期:2017-02-01 00:00:00

  • A comparative analysis of mouse and human medial geniculate nucleus connectivity: a DTI and anterograde tracing study.

    abstract::Understanding the function and connectivity of thalamic nuclei is critical for understanding normal and pathological brain function. The medial geniculate nucleus (MGN) has been studied mostly in the context of auditory processing and its connection to the auditory cortex. However, there is a growing body of evidence ...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2014.10.047

    authors: Keifer OP Jr,Gutman DA,Hecht EE,Keilholz SD,Ressler KJ

    更新日期:2015-01-15 00:00:00

  • Hemispheric asymmetries in language-related pathways: a combined functional MRI and tractography study.

    abstract::Functional lateralization is a feature of human brain function, most apparent in the typical left-hemisphere specialization for language. A number of anatomical and imaging studies have examined whether structural asymmetries underlie this functional lateralization. We combined functional MRI (fMRI) and diffusion-weig...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2006.03.011

    authors: Powell HW,Parker GJ,Alexander DC,Symms MR,Boulby PA,Wheeler-Kingshott CA,Barker GJ,Noppeney U,Koepp MJ,Duncan JS

    更新日期:2006-08-01 00:00:00

  • Multi-atlas segmentation of the whole hippocampus and subfields using multiple automatically generated templates.

    abstract:INTRODUCTION:Advances in image segmentation of magnetic resonance images (MRI) have demonstrated that multi-atlas approaches improve segmentation over regular atlas-based approaches. These approaches often rely on a large number of manually segmented atlases (e.g. 30-80) that take significant time and expertise to prod...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2014.04.054

    authors: Pipitone J,Park MT,Winterburn J,Lett TA,Lerch JP,Pruessner JC,Lepage M,Voineskos AN,Chakravarty MM,Alzheimer's Disease Neuroimaging Initiative.

    更新日期:2014-11-01 00:00:00

  • Transcranial magnetic stimulation can be used to test connections to primary motor areas from frontal and medial cortex in humans.

    abstract::Surface EMG responses (MEPs) were recorded from the relaxed first dorsal interosseous (FDI) of 16 normal subjects following transcranial magnetic stimulation (TMS) over the hand area of the primary motor cortex. These test responses were conditioned by a subthreshold stimulus applied 2-15 ms beforehand over a range of...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1006/nimg.2001.0918

    authors: Civardi C,Cantello R,Asselman P,Rothwell JC

    更新日期:2001-12-01 00:00:00

  • Segmentation of the mouse hippocampal formation in magnetic resonance images.

    abstract::The hippocampal formation plays an important role in cognition, spatial navigation, learning, and memory. High resolution magnetic resonance (MR) imaging makes it possible to study in vivo changes in the hippocampus over time and is useful for comparing hippocampal volume and structure in wild type and mutant mice. Su...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2011.06.025

    authors: Richards K,Watson C,Buckley RF,Kurniawan ND,Yang Z,Keller MD,Beare R,Bartlett PF,Egan GF,Galloway GJ,Paxinos G,Petrou S,Reutens DC

    更新日期:2011-10-01 00:00:00

  • The facilitative effect of gestures on the neural processing of semantic complexity in a continuous narrative.

    abstract::Gestures are elemental components of social communication and aid comprehension of verbal messages; however, little is known about the potential role of gestures in facilitating processing of semantic complexity in an ecologically valid setting. The goal of this study was to investigate whether cognitive load, as inde...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2019.03.054

    authors: Cuevas P,Steines M,He Y,Nagels A,Culham J,Straube B

    更新日期:2019-07-15 00:00:00

  • The morphometry of auditory cortex in the congenitally deaf measured using MRI.

    abstract::The study of congenitally deaf individuals provides a unique opportunity to understand the organization and potential for reorganization of human auditory cortex. We used magnetic resonance imaging (MRI) to examine the structural organization of two auditory cortical regions, Heschl's gyrus (HG) and the planum tempora...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章

    doi:10.1016/S1053-8119(03)00373-2

    authors: Penhune VB,Cismaru R,Dorsaint-Pierre R,Petitto LA,Zatorre RJ

    更新日期:2003-10-01 00:00:00

  • FMRI of phonemic perception and its relationship to reading development in elementary- to middle-school-age children.

    abstract::Neuroimaging studies suggest that categorical perception of speech phonemes in adults is primarily subserved by a pathway from bilateral primary auditory areas to association areas in the left middle superior temporal cortex, but the neural substrates underlying categorical speech perception in children are not yet kn...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2013.11.055

    authors: Conant LL,Liebenthal E,Desai A,Binder JR

    更新日期:2014-04-01 00:00:00

  • Unbiased tensor-based morphometry: improved robustness and sample size estimates for Alzheimer's disease clinical trials.

    abstract::Various neuroimaging measures are being evaluated for tracking Alzheimer's disease (AD) progression in therapeutic trials, including measures of structural brain change based on repeated scanning of patients with magnetic resonance imaging (MRI). Methods to compute brain change must be robust to scan quality. Biases m...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2012.10.086

    authors: Hua X,Hibar DP,Ching CR,Boyle CP,Rajagopalan P,Gutman BA,Leow AD,Toga AW,Jack CR Jr,Harvey D,Weiner MW,Thompson PM,Alzheimer's Disease Neuroimaging Initiative.

    更新日期:2013-02-01 00:00:00

  • Age-related grey matter changes in preterm infants: an MRI study.

    abstract::Grey matter (GM) maturation has not been previously studied in healthy preterm children. The purpose of this study was to evaluate the age dependency of GM development in 116 GM areas in preterm subjects. Sixty one preterm infants (corrected age: 13.7+/-9.92 months, gestational age: 33.4+/-1.9 weeks) with normal struc...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2009.03.072

    authors: Tzarouchi LC,Astrakas LG,Xydis V,Zikou A,Kosta P,Drougia A,Andronikou S,Argyropoulou MI

    更新日期:2009-10-01 00:00:00

  • Magnetic resonance imaging of cortical connectivity in vivo.

    abstract::Magnetic resonance imaging of neuronal connectivity in vivo opens up the possibility of performing longitudinal investigations on neuronal networks. This is one main reason for the attention that paramagnetic ion manganese (Mn2+) has attracted as a potential anterograde neuronal tracer for MRI experiments. However, th...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2007.12.007

    authors: Canals S,Beyerlein M,Keller AL,Murayama Y,Logothetis NK

    更新日期:2008-04-01 00:00:00

  • Mirtazapine antagonises the subjective, hormonal and neuronal effects of m-chlorophenylpiperazine (mCPP) infusion: a pharmacological-challenge fMRI (phMRI) study.

    abstract::Aberrant signalling through central 5-HT(2C) receptor pathways has been implicated in various psychiatric disorders but this has not been amenable to experimental investigation in the absence of a valid in-vivo biomarker of functional 5-HT(2C) neurotransmission. One approach is drug-challenge pharmaco-magnetic resonan...

    journal_title:NeuroImage

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.neuroimage.2011.06.049

    authors: McKie S,Richardson P,Elliott R,Völlm BA,Dolan MC,Williams SR,Anderson IM,Deakin JF

    更新日期:2011-09-15 00:00:00

  • Cerebral correlates of alerting, orienting and reorienting of visuospatial attention: an event-related fMRI study.

    abstract::The identification of brain systems contributing to different aspects of visuospatial attention is of both clinical and theoretical interest. Cued target detection tasks provide a simple means to dissociate attentional subcomponents, such as alerting, orienting or reorienting of attention. Event-related functional mag...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.neuroimage.2003.08.044

    authors: Thiel CM,Zilles K,Fink GR

    更新日期:2004-01-01 00:00:00

  • The preparation and readiness for voluntary movement: a high-field event-related fMRI study of the Bereitschafts-BOLD response.

    abstract::Activity within motor areas of the cortex begins to increase 1 to 2 s prior to voluntary self-initiated movement (termed the Bereitschaftspotential or readiness potential). There has been much speculation and debate over the precise source of this early premovement activity as it is important for understanding the rol...

    journal_title:NeuroImage

    pub_type: 临床试验,杂志文章

    doi:10.1016/s1053-8119(03)00291-x

    authors: Cunnington R,Windischberger C,Deecke L,Moser E

    更新日期:2003-09-01 00:00:00

  • Susceptibility-resistant variable-flip-angle turbo spin echo imaging for reliable estimation of cortical thickness: a feasibility study.

    abstract::The thickness of the human cerebral cortex, which provides valuable information in the studies of normal and abnormal neuroanatomy, is commonly estimated using high-resolution, volumetric magnetization-prepared rapid gradient echo (MP-RAGE) magnetic resonance imaging due to its strong T1-weighted contrast and high sig...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2011.07.070

    authors: Lee H,Kim EY,Yang KS,Park J

    更新日期:2012-01-02 00:00:00

  • Switch probability context (in)sensitivity within the cognitive control network.

    abstract::Cognitive control processes refer to the ability to flexibly adapt one's thoughts and actions in the pursuit of an internal goal. Task preparation is a central aspect of cognitive control and has generally been studied using explicitly cued task-switching paradigms. Over the last decade, numerous fMRI studies have ide...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2013.03.057

    authors: De Baene W,Brass M

    更新日期:2013-08-15 00:00:00

  • Neural correlates of processing situational relationships between a part and the whole: an fMRI study.

    abstract::Daily situations involve many objects and behaviors. To comprehend the meaning of situations, the relationships between objects, behaviors, and the situational context are important. To reveal the cortical networks involved in processing these relationships we used functional magnetic resonance imaging to compare brai...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2009.06.024

    authors: Wakusawa K,Sugiura M,Sassa Y,Jeong H,Horie K,Sato S,Yokoyama H,Tsuchiya S,Kawashima R

    更新日期:2009-11-01 00:00:00

  • Individuals with schizophrenia present hypo- and hyperactivation during implicit cueing in an inhibitory task.

    abstract:BACKGROUND:The primary purpose of this investigation was to assess the neural correlates of implicit cueing during an inhibitory task in schizophrenia when performance accuracy was matched with healthy comparison subjects. METHODS:We compared 17 individuals with chronic schizophrenia (SZ; medicated, 13.9 average years...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2006.04.189

    authors: Arce E,Leland DS,Miller DA,Simmons AN,Winternheimer KC,Paulus MP

    更新日期:2006-08-15 00:00:00

  • Realistic simulation of artefacts in diffusion MRI for validating post-processing correction techniques.

    abstract::In this paper we demonstrate a simulation framework that enables the direct and quantitative comparison of post-processing methods for diffusion weighted magnetic resonance (DW-MR) images. DW-MR datasets are employed in a range of techniques that enable estimates of local microstructure and global connectivity in the ...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2015.11.006

    authors: Graham MS,Drobnjak I,Zhang H

    更新日期:2016-01-15 00:00:00

  • Imaging dopamine receptors in humans with [11C]-(+)-PHNO: dissection of D3 signal and anatomy.

    abstract::[(11)C]-(+)-PHNO is a D3 preferring PET radioligand which has recently opened the possibility of imaging D3 receptors in the human brain in vivo. This imaging tool allows characterisation of the distribution of D3 receptors in vivo and further investigation of their functional role. The specific [(11)C]-(+)-PHNO signa...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2010.06.044

    authors: Tziortzi AC,Searle GE,Tzimopoulou S,Salinas C,Beaver JD,Jenkinson M,Laruelle M,Rabiner EA,Gunn RN

    更新日期:2011-01-01 00:00:00

  • Task demands modulate sustained and transient neural activity during visual-matching tasks.

    abstract::The extent to which a task demands verbal or non-verbal processing may influence which neural regions underlie performance. In the present study, sustained and transient responses were examined using functional magnetic resonance imaging (fMRI) in conjunction with a mixed blocked/event-related design during three visu...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2004.12.039

    authors: Darcy Burgund E,Lugar HM,Schlaggar BL,Petersen SE

    更新日期:2005-04-01 00:00:00

  • Transferring and generalizing deep-learning-based neural encoding models across subjects.

    abstract::Recent studies have shown the value of using deep learning models for mapping and characterizing how the brain represents and organizes information for natural vision. However, modeling the relationship between deep learning models and the brain (or encoding models), requires measuring cortical responses to large and ...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2018.04.053

    authors: Wen H,Shi J,Chen W,Liu Z

    更新日期:2018-08-01 00:00:00

  • Dynamics of cortical neurovascular coupling analyzed by simultaneous DC-magnetoencephalography and time-resolved near-infrared spectroscopy.

    abstract::Functional magnetic resonance imaging (fMRI) visualizes activated brain areas with a high spatial resolution. The activation signal is determined by the local change of cerebral blood oxygenation, blood volume and blood flow which serve as surrogate marker for the neuronal signal itself. Here, the complex coupling bet...

    journal_title:NeuroImage

    pub_type: 杂志文章

    doi:10.1016/j.neuroimage.2007.09.037

    authors: Mackert BM,Leistner S,Sander T,Liebert A,Wabnitz H,Burghoff M,Trahms L,Macdonald R,Curio G

    更新日期:2008-02-01 00:00:00

  • Meta-analytic clustering of the insular cortex: characterizing the meta-analytic connectivity of the insula when involved in active tasks.

    abstract::The human insula has been parcellated on the basis of resting state functional connectivity and diffusion tensor imaging. Little is known about the organization of the insula when involved in active tasks. We explored this issue using a novel meta-analytic clustering approach. We queried the BrainMap database asking f...

    journal_title:NeuroImage

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.neuroimage.2012.04.012

    authors: Cauda F,Costa T,Torta DM,Sacco K,D'Agata F,Duca S,Geminiani G,Fox PT,Vercelli A

    更新日期:2012-08-01 00:00:00