Abstract：
:The hippocampal formation plays an important role in cognition, spatial navigation, learning, and memory. High resolution magnetic resonance (MR) imaging makes it possible to study in vivo changes in the hippocampus over time and is useful for comparing hippocampal volume and structure in wild type and mutant mice. Such comparisons demand a reliable way to segment the hippocampal formation. We have developed a method for the systematic segmentation of the hippocampal formation using the perfusion-fixed C57BL/6 mouse brain for application in longitudinal and comparative studies. Our aim was to develop a guide for segmenting over 40 structures in an adult mouse brain using 30 μm isotropic resolution images acquired with a 16.4 T MR imaging system and combined using super-resolution reconstruction.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Richards K,Watson C,Buckley RF,Kurniawan ND,Yang Z,Keller MD,Beare R,Bartlett PF,Egan GF,Galloway GJ,Paxinos G,Petrou S,Reutens DCdoi
10.1016/j.neuroimage.2011.06.025subject
Has Abstractpub_date
2011-10-01 00:00:00pages
732-40issue
3eissn
1053-8119issn
1095-9572pii
S1053-8119(11)00643-4journal_volume
58pub_type
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