Abstract:
:Genomic mapping has been used to identify a region of the host genome that determines resistance to fusiform rust disease in loblolly pine where no discrete, simply inherited resistance factors had been previously found by conventional genetic analysis over four decades. A resistance locus, behaving as a single dominant gene, was mapped by association with genetic markers, even though the disease phenotype deviated from the expected Mendelian ratio. The complexity of forest pathosystems and the limitations of genetic analysis, based solely on phenotype, had led to an assumption that effective long-term disease resistance in trees should be polygenic. However, our data show that effective long-term resistance can be obtained from a single qualitative resistance gene, despite the presence of virulence in the pathogen population. Therefore, disease resistance in this endemic coevolved forest pathosystem is not exclusively polygenic. Genomic mapping now provides a powerful tool for characterizing the genetic basis of host pathogen interactions in forest trees and other undomesticated, organisms, where conventional genetic analysis often is limited or not feasible.
journal_name
Proc Natl Acad Sci U S Aauthors
Wilcox PL,Amerson HV,Kuhlman EG,Liu BH,O'Malley DM,Sederoff RRdoi
10.1073/pnas.93.9.3859subject
Has Abstractpub_date
1996-04-30 00:00:00pages
3859-64issue
9eissn
0027-8424issn
1091-6490journal_volume
93pub_type
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