Abstract:
OBJECTIVE:To assess the impact of surgical staging on treatment modification and outcome in endometrial carcinoma (EC) patients. METHODS:Two groups of histologically confirmed clinical Stage I and II EC patients, diagnosed during two time periods (1976-1984 and 1985-1991), were retrospectively compared. Sixty-five patients diagnosed during the first period were staged only clinically and treated according to a protocol based on this staging system. Fifty-six patients diagnosed during the second period were staged surgically and treatment was modified according to surgical pathological findings. RESULTS:The findings based on the surgical staging spared radiotherapy in some patients and prompted additional treatment in others. The morbidity and survival were similar in the two groups. CONCLUSIONS:Surgical pathological findings in EC patients may modify management and contribute to prognostic significance. No effect on postoperative morbidity or on actuarial survival was demonstrated.
journal_name
Eur J Gynaecol Oncoljournal_title
European journal of gynaecological oncologyauthors
Hourvitz A,Menczer J,Chetrit A,Modan Bsubject
Has Abstractpub_date
1995-01-01 00:00:00pages
357-62issue
5eissn
0392-2936issn
2709-0086journal_volume
16pub_type
杂志文章abstract::Granulosa cell tumors (GCT) constitute 70% of all ovarian sex-cord stromal tumors, which account for less than five percent of all ovarian carcinoma. The authors herein report a rare case of a ruptured GCT of the ovary in a 43-year-old female who was admitted to the emergency department with signs of acute abdomen. ...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
abstract::To investigate the influence of tamoxifen, danazol and triptorelin (a GnRH agonist) on estrogen and progesterone receptors of rat endometrium, 44 castrated Sprague-Dawley rats were divided into four equal groups, and each group received either no treatment or one of the agents. After administration of the agents, estr...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the clinical value of ultrasound-guided resection of non-palpable breast masses. MATERIALS AND METHODS:One hundred thirty-seven cases of non palpable breast mass patients who underwent surgical treatment from June 2007 to June 2012 were enrolled in this study. All patien...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2016-01-01 00:00:00
abstract:SUMMARY:A case of cauda equina metastasis from ovarian serous papillary adenocarcinoma in a 51-year-old patient is reported. The clinical significance and different hypotheses on the metastatic route to the spine are discussed. ...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章,评审
doi:
更新日期:1996-01-01 00:00:00
abstract::The role of a number of parameters was evaluated in 172 patients with advanced ovarian tumors. The clinical stage appears to be one of the most important of these parameters. Thus 3 years survival of patients in stage II was 40% whereas of those in stage IV only 5%. Granulosa cell tumors and mucinous cystadenocarcinom...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
abstract::In a retrospective study, a total of 120 ovarian cancer patients were paired in terms of staging, grading, patent age, and operative and cytostatic therapy. Half of the patients underwent radioimmunoscintigraphy for diagnostic purposes. From the point of view of possible adjuvant immunological therapy, we investigated...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::A 15 year retrospective study of chemotherapy response to multiple regimens employed in 78 evaluable patients with advanced uterine sarcoma was performed. Single agent activity was noted with doxorubicin, methotrexate, and cisplatin (5-11% response rate). Effective multigent regimens included cyclophosphamide, vincris...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:The objective was to improve the design of the indwelling-intrauterine tube (IIUT) for brachy-radiotherapy of cervical cancer or sleeve, specifically one that would not require stitching to retain it properly in the uterus for periods of one to two weeks and to ensure hygiene by making them disposable, thinne...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
abstract::Malignant mixed Müllerian tumor (MMMT) of the female genital tract is uncommon and extremely rare in the Fallopian tube. We describe a case of primary MMMT of the Fallopian tube with carcinomatous and heterologous mesenchymal components in a 60-year-old woman. The patient underwent total abdominal hysterectomy, bilate...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract::A primary leiomyosarcoma (LMS) arising from the left fallopian tube in a perimenopausal 48-year-old woman is reported. Primary tubal LMS is an uncommon, exceedingly rare neoplasm, accounting for only a few reported cases so far. To our knowledge, the present case is the 17th tubal LMS reported in the English-language ...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::Radiotherapy and surgery are important radical treatment options for cervical cancer, but the presence of a pelvic kidney complicates the situation. Fine radiation technique can help avoiding side effects. Radiation to the modified pelvis using intensity modulated radiotherapy (IMRT) followed by brachytherapy, while a...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:To determine the frequency of synchronous primary neoplasia of the ovaries in patients with primary malignant neoplasia of the uterus, and to analyze the clinical and histological characteristics of these cases. MATERIALS AND METHODS:Clinicopathological data from a series of patients treated for primary mali...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::Malignant and non-malignant serosal fluids were found to be associated with high serum levels of CA-125, suggesting that the presence of fluid in the serosal cavities may stimulate its release. In this study, we investigated the relationship between serum CA-125 levels and peritoneal irritation during continuous ambul...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::256 patients of the years 1965-1979 who suffered from collum carcinoma stage T1b were reviewed. Most of the neoplasmas were squamous cell carcinoma (81%). By tumor screening only 21% of the carcinomas were detected. The treatment was in most of the cases a radical hysterectomy (Wertheim-Meigs). Postoperative radiother...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::A case of secretory (juvenile) carcinoma of the breast is reported in a 31-year-old woman. Secretory carcinoma in adults is rare, only twenty-seven cases previously reported. It is known to have a more favourable prognosis than the conventional ductal carcinoma. The most adequate treatment appears to be a simple maste...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::Uterine tumors resembling ovarian sex cord tumors (UTROSCTs) are very rare uterine neoplasms. They mostly behave in a benign fashion but cases were reported with extra-uterine spread. There are less than 50 cases reported in the literature so far according to the present authors' knowledge. We report a case of 45-year...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2016-01-01 00:00:00
abstract::The efficacy of a new device, "the Endopap" endometrial cell sampler in obtaining specimens for cytological examination to detect precursors of malignancy of the endometrium was assessed in 140 asymptomatic and sympomatic women. The cytological results as compared with hystological diagnosis on curettage specimens by ...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract:PURPOSE:To establish whether information leaflets and appointment reminders improve attendance for diagnostic colposcopy. DESIGN & SETTING:Randomised controlled trial in an inner city colposcopy clinic. PARTICIPANTS:500 women newly referred to the colposcopy clinic with abnormal cervical screening smear results were ...
journal_title:European journal of gynaecological oncology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2004-01-01 00:00:00
abstract::All malignant cells appear to have increased needs for glucose in vitro as well as in vivo. The enhanced glucose uptake is mediated through transporters (Gluts), whose action and expression are regulated by oncogenes and growth factors. Cyclin D1 is a nuclear protein that plays an important role in regulating the cell...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::The authors present a case of intra-abdominal recurrent leiomyosarcoma invading a large area of the abdominal wall. The patient underwent cytoreductive surgery, including resection of the rectus abdominis muscle, followed by reconstruction of the defect using synthetic mesh. The tumor was surgically removed by en bloc...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
abstract::The purpose of our study was to examine the concordance among colposcopy, cytology, and histology in the diagnoses of intraepithelial lesions of the uterine cervix. We compared the results of Pap tests, biopsies, and colposcopy in 190 patients, who had histologically proven CIN and/or HPV infection, using histology as...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::Primary adenocarcinoma of the vulva is uncommon, and cloacogenic adenocarcinoma of the vulva is extremely rare. Here the authors report a vulvar neoplasm, arising in continuity with the epidermis, characterized by villoglandular architecture, and mucinous-type ep- ithelium with intestinal differentiation (goblet cells...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章,评审
doi:
更新日期:2017-01-01 00:00:00
abstract::This study deals with the monitoring of plasmatic levels of malondialdehyde, as the main indicator of oxidative damage to biomembranes. Malondialdehyde is determined by high-performance liquid chromatography (HPLC) after derivatization employing 2,4-dinitrophenylhydrazine. A clinical study involving 20 female patients...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
abstract:PURPOSE OF INVESTIGATION:Infertility represents one of the main sequelae of cytotoxic therapy given for various malignant diseases. Because dividing cells are more sensitive to cytotoxic effects than are cells at rest, it has been hypothesized that inhibition of the pituitary-gonadal axis may facilitate the preservatio...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract::Four patients with hypersensitivity reaction to carboplatin of variable severity, after previous uneventful cisplatin and carboplatin treatment, are described. Skin testing performed in two of the patients suggests a cross-reaction with cisplatin but was negative with carboplatin in one of them. The mechanism of hyper...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::According to recent epidemiological studies on ovarian cysts during pregnancy one out of 600 are, in most cases, benign neoformations. The most frequent histological type reported is mature cystic teratoma (50% of the cases), followed by functional cysts (13%), benign cystadenomas (20%) and ovarian cancer (0.6%). Most...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章,评审
doi:
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:This study aims to investigate the correlation and clinical significance of hormone receptors and the expressions of HER-2 and Ki-67 in breast cancer primary lesions and lymph node metastatic tissues. METHODS:83 cases were studied, who were performed breast cancer surgeries and confirmed the ipsilateral axil...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2015-01-01 00:00:00
abstract::In an aim to evaluate the diagnostic efficacy of preoperative abdominal-pelvic CT for the prediction of suboptimal cytoreduction of epithelial ovarian carcinoma (EOC) at primary surgery, CT scans of 48 patients who underwent primary surgery for EOC were retrospectively analyzed. The presence of at least one of the fol...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:Polyps are covered with endometrial epithelium and composed of varying proportions of gland, stroma, and blood vessels. Traditionally, endometrial polyps are accepted as a precursor of cancer. The aim of this study was to evaluate the relationship between malignancies arising on endometrial polyps and prec...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Patients with invasive hydatidiform moles (IHM) have a good prognosis. Even if disease has spread, monocytostatic treatment might be sufficient if the diagnosis has been histologically confirmed. Established classifications divide gestational trophoblastic disease (GTD) including choriocarcinoma into cases w...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章,评审
doi:
更新日期:2005-01-01 00:00:00