Cloacogenic adenocarcinoma of the vulva: one new case and literature review.

Abstract:

:Primary adenocarcinoma of the vulva is uncommon, and cloacogenic adenocarcinoma of the vulva is extremely rare. Here the authors report a vulvar neoplasm, arising in continuity with the epidermis, characterized by villoglandular architecture, and mucinous-type ep- ithelium with intestinal differentiation (goblet cells). Histochemistry, immunohistochemistry, and gene mutation analysis revealed a colon-like pattern, except for CK7 expression. Extensive workup failed to reveal other primary cancers. In order to provide a much bet- ter experience for diagnosis, the authors compared the previously published cases with the present case regarding clinical presentation and histopathologic aspect. They believe that the notion of the tumor arising from cloacal remnants is a more acceptable viewpoint, and its behavior is mostly indolent. In the present case, a wide local excision was sufficient for radical cure.

journal_name

Eur J Gynaecol Oncol

authors

He SR,Deng WH,Yang L,Yang K,Cui D,Liu DG

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

296-302

issue

2

eissn

0392-2936

issn

2709-0086

journal_volume

38

pub_type

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