Orally administered bovine lactoferrin inhibits bacterial translocation in mice fed bovine milk.

Abstract:

:Feeding of bovine milk to mice induced a high incidence of bacterial translocation from the intestines to the mesenteric lymph nodes, and the bacteria involved were mainly members of the family Enterobacteriaceae. Supplementation of the milk diet with bovine lactoferrin or a pepsin-generated hydrolysate of bovine lactoferrin resulted in significant suppression of bacterial translocation. Our findings suggest that this ability of lactoferrin to inhibit bacterial translocation may be due to its suppression of bacterial overgrowth in the guts of milk-fed mice.

journal_name

Appl Environ Microbiol

authors

Teraguchi S,Shin K,Ogata T,Kingaku M,Kaino A,Miyauchi H,Fukuwatari Y,Shimamura S

doi

10.1128/AEM.61.11.4131-4134.1995

subject

Has Abstract

pub_date

1995-11-01 00:00:00

pages

4131-4

issue

11

eissn

0099-2240

issn

1098-5336

journal_volume

61

pub_type

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