当前位置： SCI文献检索 > NEUROSCIENCE期刊下所有文献 > Detection of putative dopamine receptors in neurites outgrowing from locust central nervous system explants using anti-idiotypic dopamine antibodies.

Detection of putative dopamine receptors in neurites outgrowing from locust central nervous system explants using anti-idiotypic dopamine antibodies.

Abstract：

:Organotypic cultures established from the third thoracic ganglion of locust embryo have been used to investigate dopamine receptors. In this in vitro system, neurites emerge directly from the explants and form a dense network around the explants, presenting cell surface freely exposed for experimental labelling. Polyclonal anti-idiotypic antibodies raised in rabbits to antibodies against dopamine conjugate, and previously found to bind to dopamine receptors, have been used to investigate putative dopamine receptors in these neurites. Immunocytochemical detection by light microscopy employing immunofluorescence labelling, was correlated with electron microscopy, using peroxidase staining. In addition to a location for dopamine receptors on the neurite surface, intracellular binding sites were also found in neurites. This internal labelling might represent an intracellular pool of dopamine receptor precursors. The labelling was specific in that it was not present when the anti-idiotypic dopamine antibodies were replaced with non-immune serum or when preincubation with conjugated dopamine preceded incubation with anti-idiotypic dopamine antibodies.

journal_name

Neuroscience

journal_title

Neuroscience

authors

Vanhems E,Delbos M,Geffard M,Viellemaringe J

doi

10.1016/0306-4522(94)90088-4

subject

Has Abstract

pub_date

1994-02-01 00:00:00

pages

649-55

issue

3

eissn

0306-4522

issn

1873-7544

pii

0306-4522(94)90088-4

journal_volume

58

pub_type

杂志文章

相关文献

NEUROSCIENCE文献大全
  • Pathological gamma oscillations, impaired dopamine release, synapse loss and reduced dynamic range of unitary glutamatergic synaptic transmission in the striatum of hypokinetic Q175 Huntington mice.

    abstract：:Huntington's disease (HD) is a severe genetically inherited neurodegenerative disorder. Patients present with three principal phenotypes of motor symptoms: choreatic, hypokinetic-rigid and mixed. The Q175 mouse model of disease offers an opportunity to investigate the cellular basis of the hypokinetic-rigid form of HD...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2015.10.039

    authors： Rothe T,Deliano M,Wójtowicz AM,Dvorzhak A,Harnack D,Paul S,Vagner T,Melnick I,Stark H,Grantyn R

    更新日期：2015-12-17 00:00:00

  • Humanized Foxp2 specifically affects cortico-basal ganglia circuits.

    abstract：:It has been proposed that two amino acid substitutions in the transcription factor FOXP2 have been positively selected during human evolution and influence aspects of speech and language. Recently it was shown that when these substitutions are introduced into the endogenous Foxp2 gene of mice, they increase dendrite l...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2010.11.042

    authors： Reimers-Kipping S,Hevers W,Pääbo S,Enard W

    更新日期：2011-02-23 00:00:00

  • Voxel-based morphometry study of the insular cortex in female patients with current and remitted depression.

    abstract：OBJECTIVE:Women are more prone to major depressive disorders (MDDs) and the incidence of MDD in women is almost twice that of men. Insular cortex abnormalities are a common finding in neuroanatomical studies of patients with MDD. However, it remains largely unclear whether female MDD patients at different clinical stag...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2013.12.058

    authors： Liu CH,Jing B,Ma X,Xu PF,Zhang Y,Li F,Wang YP,Tang LR,Wang YJ,Li HY,Wang CY

    更新日期：2014-03-14 00:00:00

  • A Single Bout of High-intensity Interval Exercise Increases Corticospinal Excitability, Brain-derived Neurotrophic Factor, and Uncarboxylated Osteolcalcin in Sedentary, Healthy Males.

    abstract：:Exercise induces neuroplasticity in descending motor pathways facilitating motor learning, and as such it could be utilized as an intervention in neurorehabilitation, for example when re-learning motor skills after stroke. To date, however, the neurophysiological and molecular mechanisms underlying exercise-induced ne...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2020.03.042

    authors： Nicolini C,Michalski B,Toepp SL,Turco CV,D'Hoine T,Harasym D,Gibala MJ,Fahnestock M,Nelson AJ

    更新日期：2020-06-15 00:00:00

  • Role of lateral and feedback connections in primary visual cortex in the processing of spatiotemporal regularity - a TMS study.

    abstract：:Our human visual system exploits spatiotemporal regularity to interpret incoming visual signals. With a dynamic stimulus sequence of four collinear bars (predictors) appearing consecutively toward the fovea, followed by a target bar with varying contrasts, we have previously found that this predictable spatiotemporal ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2014.01.027

    authors： Roebuck H,Bourke P,Guo K

    更新日期：2014-03-28 00:00:00

  • Minimal NF-κB activity in neurons.

    abstract：:Nuclear factor-kappa B (NF-κB) is a ubiquitous transcription factor that regulates immune and cell-survival signaling pathways. NF-κB has been reported to be present in neurons wherein it reportedly responds to immune and toxic stimuli, glutamate, and synaptic activity. However, because the brain contains many cell ty...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2013.07.013

    authors： Listwak SJ,Rathore P,Herkenham M

    更新日期：2013-10-10 00:00:00

  • Epigallocatechin gallate induces extracellular degradation of amyloid β-protein by increasing neprilysin secretion from astrocytes through activation of ERK and PI3K pathways.

    abstract：:Amyloid-β (Aβ) production and clearance in the brain is a crucial focus of investigations into the pathogenesis of Alzheimer disease. Imbalance between production and clearance leads to accumulation of Aβ. The important Aβ-degrading enzymes in the brain are neprilysin (NEP) and insulin-degrading enzyme (IDE), and defe...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2017.08.030

    authors： Yamamoto N,Shibata M,Ishikuro R,Tanida M,Taniguchi Y,Ikeda-Matsuo Y,Sobue K

    更新日期：2017-10-24 00:00:00

  • Carnosine-like immunoreactivity in astrocytes of the glial tubes and in newly-generated cells within the tangential part of the rostral migratory stream of rodents.

    abstract：:In the nervous system, the aminoacylhistidine dipeptide carnosine (beta-alanyl-L-histidine) has been shown to be expressed in the olfactory receptor neurons and in brain astrocytes. Using immunocytochemical techniques, we report here a dense carnosine-like immunoreactivity in the subependymal layer of the rodent foreb...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(97)00596-4

    authors： Peretto P,Bonfanti L,Merighi A,Fasolo A

    更新日期：1998-07-01 00:00:00

  • Autoradiographic localization in rat brain of kappa opiate binding sites labelled by [3H]bremazocine.

    abstract：:[3H]Bremazocine, in the presence of saturating concentrations of mu and delta receptor blocking agents, was used to label putative kappa opiate binding sites in rat brain. The binding of [3H]bremazocine under these conditions was completely displaced with high affinity by U-50488H and dynorphin1-17, and the potency of...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(86)90302-7

    authors： Morris BJ,Herz A

    更新日期：1986-11-01 00:00:00

  • Closed-head minimal traumatic brain injury produces long-term cognitive deficits in mice.

    abstract：:Victims of minimal traumatic brain injury (mTBI) do not show clear morphological brain defects, but frequently suffer lasting cognitive deficits, emotional difficulties and behavioral disturbances. In the present study we adopted a non-invasive closed-head weight-drop mouse model to produce mTBI. We examined the effec...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(03)00048-4

    authors： Zohar O,Schreiber S,Getslev V,Schwartz JP,Mullins PG,Pick CG

    更新日期：2003-01-01 00:00:00

  • Increase in AMPA receptors in aged memory-impaired rats is not associated with increase in monoamine oxidase B levels.

    abstract：:Aged rats may be behaviorally classified as either cognitively impaired or unimpaired based upon their performance in the Morris water maze task. In aged Long-Evans rats, emergence of functional deficits has been related to the increase in the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor s...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(00)00459-0

    authors： Andrés N,Rodríguez MJ,Andrade C,Rowe W,Quirion R,Mahy N

    更新日期：2000-01-01 00:00:00

  • l-DOPA-induced dyskinesia is associated with a deficient numerical downregulation of striatal tyrosine hydroxylase mRNA-expressing neurons.

    abstract：:l-3,4-Dihydroxyphenylalanine (l-DOPA) is the therapeutic gold standard in Parkinson's disease. However, most patients develop debilitating abnormal involuntary movements termed l-DOPA-induced dyskinesia (LID) as therapy-complicating side effects. The underlying mechanisms of LID pathogenesis are still not fully unders...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2016.06.017

    authors： Klietz M,Keber U,Carlsson T,Chiu WH,Höglinger GU,Weihe E,Schäfer MK,Depboylu C

    更新日期：2016-09-07 00:00:00

  • Membrane specializations and extracellular material associated with host astrocytes in peripheral neural transplants.

    abstract：:The work of Aguayo and colleagues [Aguayo, David and Bray (1981) J. Exp. Biol. 95, 231-240] demonstrates that grafts of peripheral neural tissue are able to induce regenerative elongation of cut axons in the adult central nervous system. Elucidation of the mechanism of this response requires an understanding of the ce...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(87)90261-2

    authors： Lawrence JM,Raisman G

    更新日期：1987-03-01 00:00:00

  • Tissue plasminogen activator contributes to morphine tolerance and induces mechanical allodynia via astrocytic IL-1β and ERK signaling in the spinal cord of mice.

    abstract：:Accumulating evidence indicates that activation of spinal cord astrocytes contributes importantly to nerve injury and inflammation-induced persistent pain and chronic opioid-induced antinociceptive tolerance. Phosphorylation of extracellular signal-regulated kinase (pERK) and induction of interleukin-1 beta (IL-1β) in...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2013.05.018

    authors： Berta T,Liu YC,Xu ZZ,Ji RR

    更新日期：2013-09-05 00:00:00

  • The relation between transmitter release and Ca2+ entry at the mouse motor nerve terminal: role of stochastic factors causing heterogeneity.

    abstract：:The relation between quantal transmitter release and presynaptic Ca2+/Ba2+ entry at the mouse neuromuscular junction was studied, making use of the finding that in the presence of Ba2+ trains of nerve stimuli or brief nerve terminal depolarizations elicit "tails" of raised miniature end-plate potential frequency (fm) ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(92)90305-l

    authors： Quastel DM,Guan YY,Saint DA

    更新日期：1992-12-01 00:00:00

  • Effects of taurine and ketamine on bovine retinal membrane lipid peroxidation.

    abstract：:Lipid peroxidation disrupts membrane integrity and causes structural and functional alterations in ischemic tissues. Taurine and ketamine are putative ischemic protectants that affect Ca2+ influx. Here we report the influence of these compounds on lipid peroxidation in subcellular fractions, isolated cells and intact ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(91)90241-f

    authors： Zhou M,Ma T,Tseng MT

    更新日期：1991-01-01 00:00:00

  • Selective effects of neonatal handling on rat brain N-methyl-D-aspartate receptors.

    abstract：:Neonatal handling, an experimental model of early life experiences, is known to affect the hypothalamic-pituitary-adrenal axis function thus increasing adaptability, coping with stress, cognitive abilities and in general brain plasticity-related processes. A molecule that plays a most critical role in such processes i...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2009.09.032

    authors： Stamatakis A,Toutountzi E,Fragioudaki K,Kouvelas ED,Stylianopoulou F,Mitsacos A

    更新日期：2009-12-29 00:00:00

  • Myelin-induced inhibition in a spiral ganglion organ culture - Approaching a natural environment in vitro.

    abstract：:The performance of a cochlear implant depends on the defined interaction between afferent neurons of the spiral ganglion and the inserted electrode. Neurite outgrowth can be induced by neurotrophins such as brain-derived neurotrophic factor (BDNF) via tropomyosin kinase receptor B (TrkB). However, neurotrophin signali...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2017.05.053

    authors： Kramer B,Tropitzsch A,Müller M,Löwenheim H

    更新日期：2017-08-15 00:00:00

  • Input-output relations in the entorhinal cortex-dentate-hippocampal system: evidence for a non-linear transfer of signals.

    abstract：:In the current study we analyzed the input-output relations in the entorhinal-dentate-hippocampal system, a major network involved in long-term memory. In anesthetized guinea pigs, the system was driven by activation of perforant path neurons in the entorhinal cortex (ENT), via presubicular fibers directly stimulated ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2006.06.001

    authors： Bartesaghi R,Migliore M,Gessi T

    更新日期：2006-09-29 00:00:00

  • "Compensated hyperosmolarity" of cerebrospinal fluid and the development of hydrocephalus.

    abstract：:Acute osmolar loading of cerebrospinal fluid within one lateral ventricle of dogs was examined as a cause of water extraction from the bloodstream and an increase in intracranial pressure. We have shown that a certain amount of (3)H₂O from the bloodstream enters osmotically loaded cerebrospinal fluid significantly fas...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2013.06.022

    authors： Klarica M,Miše B,Vladić A,Radoš M,Orešković D

    更新日期：2013-09-17 00:00:00

  • Long-term changes of ionotropic glutamate and GABA receptors after unilateral permanent focal cerebral ischemia in the mouse brain.

    abstract：:Long-term hyperexcitability was found after unilateral, permanent middle cerebral artery occlusion in exofocal neocortical areas of the adult mouse [Mittmann et al. (1998) Neuroscience 85, 15-27]. The aim of the present study was to test the hypothesis in an identical paradigm of ischemia. whether alterations in the d...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(97)00656-8

    authors： Qü M,Mittmann T,Luhmann HJ,Schleicher A,Zilles K

    更新日期：1998-07-01 00:00:00

  • Chemically defined feedback connections from infragranular layers of sensory association cortices in the rat.

    abstract：:The primary visual (V1), auditory (AI), and somatosensory (SI) cortices are reciprocally connected with their respective sensory association cortices. In the rat, we have previously demonstrated that some of the connections arising from the secondary somatosensory (SII) and parietal insular (PA) cortices and terminati...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2003.08.056

    authors： Bai WZ,Ishida M,Arimatsu Y

    更新日期：2004-01-01 00:00:00

  • Distribution of GABA immunoreactivity in the optic tectum of the frog: a light and electron microscopic study.

    abstract：:GABA immunoreactivity was studied in the optic tectum of the frog, Rana esculenta, by postembedding immunohistochemical methods at the light and electron microscopic levels. Nearly one-third of the total population of tectal cells appeared to be GABA-immunoreactive. The proportion of stained neurons was highest in lay...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(91)90051-o

    authors： Antal M

    更新日期：1991-01-01 00:00:00

  • Lipofectin-facilitated transfer of cholecystokinin gene corrects behavioral abnormalities of rats with audiogenic seizures.

    abstract：:To evaluate the potential for lipofectin-mediated central nervous system gene transfer, the plasmid coding for cholecystokinin was administered intracerebroventricularly to rats, which have congenital audiogenic seizures and high responses to peripheral electric stimulation-induced analgesia. Previous studies had show...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(96)00420-4

    authors： Zhang LX,Li XL,Smith MA,Post RM,Han JS

    更新日期：1997-03-01 00:00:00

  • Laminar organization of the substantia nigra pars reticulata in the cat.

    abstract：:Using a semihorizontal section plane tangential to the ventral surface of the cerebral peduncle, the authors re-examined cyto-, myelo- and dendroarchitecture, acetylcholinesterase activity, afferent fibers, and efferent projection neurons of the substantia nigra pars reticulata. In the semihorizontal section plane, th...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(90)90390-p

    authors： Tokuno H,Nakamura Y,Kudo M,Kitao Y

    更新日期：1990-01-01 00:00:00

  • When a line is a number: color yields magnitude information in a digit-color synesthete.

    abstract：:The phenomenon of synesthesia has received a great deal of interest recently in the scientific literature. Many previous studies stressed the unidirectional nature of this phenomenon. For example, color-grapheme synesthetes automatically perceive achromatic numbers as colored (e.g. 7 is turquoise). Conversely, colors ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2005.08.057

    authors： Cohen Kadosh R,Henik A

    更新日期：2006-01-01 00:00:00

  • Diminished prevalence but preserved synaptic distribution of N-methyl-D-aspartate receptor subunits in the methyl CpG binding protein 2(MeCP2)-null mouse brain.

    abstract：:In this study, we examined the prevalence and distribution of NMDA receptor subunits within crude synaptic membranes derived from the brains of mice lacking methyl CpG binding protein 2 (MeCP2). Our results show that the distribution of NMDA receptor subunits within the detergent soluble, detergent resistant, and post...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2010.03.065

    authors： Maliszewska-Cyna E,Bawa D,Eubanks JH

    更新日期：2010-07-14 00:00:00

  • Topography of centrifugal acetylcholinesterase-positive fibres in the olfactory bulb of the rat: evidence for original projections in atypical glomeruli.

    abstract：:An original pathway of centrifugal acetylcholinesterase-positive fibres is described in the olfactory bulb of the rat. A dense network of positive fibres spreads out superficially at the boundaries of the lateral olfactory tract and the glomerular layer. These labelled fibres converge towards atypical glomerular struc...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(87)90183-7

    authors： Zheng LM,Ravel N,Jourdan F

    更新日期：1987-12-01 00:00:00

  • Ethanol versus lipopolysaccharide-induced hypothermia: involvement of urocortin.

    abstract：:The urocortin1 (Ucn1) neurons of the mid-brain-localized Edinger-Westphal nucleus (EW) are robustly responsive to ethanol (EtOH) administration, and send projections to the dorsal raphe nucleus (DRN), which contains corticotropin-releasing factor type 2 receptors (CRF2) that are responsive to Ucn1. In addition, the DR...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2005.03.037

    authors： Turek VF,Ryabinin AE

    更新日期：2005-01-01 00:00:00

  • Muscle resistance to slow ramp weakly depends on activation level.

    abstract：:The mechanical response of human m. flexor pollicis longus to slow (3.2 degrees/s) linear stretch by 5.5 degrees was measured during sustained (45-60 s, 9-13.5 p.p.s.) unfused tetanus evoked by electrical stimulation. The stiffness increased during unfused tetanus. At the late phase of unfused tetanus it was 1.8 +/- 0...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(97)00130-9

    authors： Gurfinkel VS,Ivanenko YP,Levik YS

    更新日期：1997-09-01 00:00:00